| ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Patent applications |
| Patent application number | Title | Published |
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| 20120119926 | Encoding and Decoding Information - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time. All of the states of the digits in the received signal are represented by events in the time-based code. | 05-17-2012 |
| 20110299555 | ERROR CONTROL CODING FOR ORTHOGONAL DIFFERENTIAL VECTOR SIGNALING - Using a transformation based, at least in part, on a non-simple orthogonal matrix, data may be transmitted over a data bus in a manner that is resilient to one or more types of signal noise, that does not require a common reference at the transmission and acquisition points, and/or that has a pin-efficiency that is greater than 50% and may approach that of single-ended signaling. Such transformations may be implemented in hardware in an efficient manner. The transformation may be combined with methods from forward error correction to lower the required transmission power. | 12-08-2011 |
| 20110236432 | Coated Medical Device and Method of Coating a Medical Device to Reduce Fibrosis and Capsule Formation - Coating for a medical device comprising cell-adhesive proteins having the ability to reduce fibrous reaction, said coating being in the form of separate islets having an individual area which is less than 12 μm | 09-29-2011 |
| 20110207157 | Labelling of Fusion Proteins With Synthetic Probes - The invention relates to new proteins called alkylcytosine transferases (ACTs) derived from O | 08-25-2011 |
| 20110201514 | Methods Using 06-Alkylguanine-DNA Alkytransferase - A method of using O | 08-18-2011 |
| 20110165593 | Mutants of 06-Alkylguanine-DNA Alkyltransferase - The invention relates to AGT mutants showing, when compared to the wild type human AGT, two or more advantageous properties selected from (a) reduced DNA interaction; (b) localisation of the expressed protein in eukaryotic cells that is no longer restricted to the nucleus; (c) improved expression yield as soluble protein and improved stability in various hosts; (d) improved stability under oxidising conditions; (e) improved stability within cells after reaction with a substrate; (f) improved stability outside cells before and after reaction with a substrate; (g) improved in vitro solubility; (h) improved reactivity against O | 07-07-2011 |
| 20110106062 | System and Method For In Vivo Delivery of Antibodies and Fragments Thereof - The present invention is directed to devices and methods for in situ delivering an antibody or a fragment thereof to a host. In particular, the invention relates to devices and methods for in situ delivering an antibody or a fragment thereof to patient suffering for a neurodegenerative disorder or other diseases treated by antibody administration. | 05-05-2011 |
| 20100248388 | Solid Phase Extraction and Ionization Device - A plate for laser desorption ionization mass spectrometry comprising an electrically conductive substrate ( | 09-30-2010 |
| 20100133636 | SINGLE PHOTON DETECTOR AND ASSOCIATED METHODS FOR MAKING THE SAME - A semiconductor device includes a semiconductor substrate, a photon avalanche detector in the semiconductor substrate. The photon avalanche detector includes an anode of a first conductivity type and a cathode of a second conductivity type. A guard ring is in the semiconductor substrate and at least partially surrounds the photon avalanche detector. A passivation layer of the first conductivity type is in contact with the guard ring to reduce an electric field at an edge of the photon avalanche detector. | 06-03-2010 |
| 20100090105 | Ionization Device - A plate for matrix-assisted laser desorption ionization (MALDI) mass spectrometry comprising an electrically conductive substrate ( | 04-15-2010 |
| 20100075394 | Method of Crosslinking Two Objects of Interest - The invention provides a method of crosslinking two objects of interest, comprising the steps of: i) providing a fusion protein comprising at least a first protein and a second protein, wherein both the first and the second protein are, based on their structure and function, capable of forming a covalent bond with given substrates, and which first and second proteins are of substantially non-overlapping substrate selectivity, preferably of different substrate specificity; ii) providing a first object of interest, comprising a substrate moiety for the first protein of the said fusion protein, and providing a second object of interest, comprising a substrate moiety for the second protein of the said fusion protein; and iii) reacting said first protein of the fusion protein with the substrate moiety of said first object, and reacting said second protein of the fusion protein with the substrate moiety of said second object, thereby covalently crosslinking the first object to the second object via the said fusion protein. Most prominent applications of the disclosed method are, due to the straight-forward, reliable, directional and fast crosslinking reactions: the derivatization of cells, antibodies and the crosslinking of proteins. | 03-25-2010 |
| 20100014642 | COLLIMATOR - The present invention is directed to a collimator that comprises grooves or channels in the submicrometer to micrometer range. The present invention is also related to uses of a collimator and collimator holder as described herein as well as apparatuses comprising the same. | 01-21-2010 |
| 20100009409 | MOLECULAR VARIANT FIBRINOGEN FUSION PROTEINS - Fibrinogen fusion proteins, methods of making, and methods of using fibrinogen fusion proteins are described. In a preferred embodiment the fibrinogen fusion protein contains a truncated Aα chain of fibrinogen. The Aα chain contains truncation site, which is a deletion of amino acids at its C-terminal region. A non-fibrinogen protein or peptide is C-terminally attached to the truncation site. The fibrinogen fusion proteins can be used alone or mixed with native fibrinogen to form fibrin polymer. | 01-14-2010 |
| 20100006441 | APPARATUS FOR MANIPULATING, MODIFYING AND CHARACTERIZING PARTICLES IN A MICRO CHANNEL - Microfluidic system comprising a space for containing a liquid and at least one lateral chamber in communication with said space, said lateral chamber containing a metal electrode. The lateral chamber and the space are designed to be filled by the same or different liquid when the system is active. | 01-14-2010 |
| 20090305286 | Method for the Identification of Suitable Fragmentation Sites in a Reporter Protein - The invention concerns a combinatorial method for the generation of new split-protein sensors, and its application towards the (β/α) | 12-10-2009 |
| 20090143597 | Ionic Liquids Based on Imidazolium Salts Incorporating a Nitrile Functionality - Novel chemical compounds of the general formula | 06-04-2009 |
| 20090068275 | Process for the Manufacture of Powders of Inhalable Medicaments - The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor
| 03-12-2009 |
