| DTherapeutics, LLC Patent applications |
| Patent application number | Title | Published |
| 20090322749 | SYSTEMS AND METHODS FOR EXTRACTING A CURVE-SKELETON FROM A VOLUMETRIC IMAGE OF A VESSEL - An accurate analysis of the spatial distribution and intravascular pattern of blood flow in any organ must be based on detailed morphometry (diameters, lengths, vessel numbers, branching pattern, branching angles, etc.) of the organ vasculature. Despite the significance of detailed morphometric data, there is relative scarcity of database on vascular anatomy, mainly because the process is extremely labor intensive. Novel methods in the form of a segmentation algorithm for semi-automation of morphometric data extraction are provided. The extraction algorithm is based on a topological analysis of a vector field generated by the normal vectors of the extracted vessel wall. With this approach, special focus is made on achieving the highest accuracy of the measured values, with excellent results when compared to manual measurements of the main trunk of the coronary arteries with microscopy. | 12-31-2009 |
| 20090319020 | DEVICES, SYSTEMS, AND METHODS FOR PROMOTING ENDOTHELIALIZATION - Devices, systems, and methods for promoting endothelialization and preventing restenosis are disclosed. At least some of the embodiments disclosed herein promote endothelialization and prevent restenosis by reducing local blood flow turbulence. At least some of the embodiments disclosed herein promote endothelialization and prevent restenosis by directing endothelial progenitor cells to a targeted site using magnetic and other means. | 12-24-2009 |
| 20090281650 | SYSTEMS AND METHODS FOR DESIGNING ENERGY EFFICIENT MICROFLUIDIC CHANNEL DEVICES - In at least one embodiment, a method for diagnosing vascular disease is provided, the method comprising the steps of obtaining a vessel image showing a vasculature of a vessel identifying at least two measurements from the vasculature of the vessel, the measurements relating to at least two parameters, calculating a relationship between the at least two parameters from the at least two measurements to generate one or more vasculature data points, and comparing the one or more vasculature data points to data relative to a model vasculature to determine the extent of vascular disease. In an another embodiment, a method for diagnosing vascular disease in a patient's vascular tree is provided, the method comprising the steps of generating a model vascular tree from a minimum energy hypothesis calculation, and comparing the patient's vascular tree with the model vascular tree to determine the extent of vascular disease. | 11-12-2009 |
| 20090082698 | DEVICES, METHODS, AND SYSTEMS FOR SIZING OF A GASTRIC POUCH - Devices, methods, and systems for measuring the size of gastric pouches. At least some embodiments include a catheter comprising an outer elongate tube, an inner elongate tube disposed within the outer elongate tube, a proximal balloon attached to the outer elongate tube, a distal balloon having a first end attached to the outer elongate tube and a second end attached to the inner elongate tube, at least two detection electrodes positioned on the outer elongate tube relative to at least two excitation electrodes, and a pressure transducer positioned on the outer elongate tube. | 03-26-2009 |