| Diatos Patent applications |
| Patent application number | Title | Published |
|---|
| 20120010124 | Cell Penetrating Peptide Conjugates for Delivering of Nucleic Acids into a Cell - The invention provides cell penetrating peptide-nucleic acid conjugates having the formula P-L-N, wherein P is a cell penetrating peptide, N is a nucleic acid, preferably an oligonucleotide and more preferably a siRNA, and L is a hydrophilic polymer, preferably a polyethylene glycol (PEG)-based linker linking P and N together. Compositions, methods of use and methods for producing such conjugates are also disclosed. | 01-12-2012 |
| 20100221235 | Compositions and Methods for Treating Lysosomal Storage Diseases - The invention relates to chimeric polypeptides comprising a lysosomal peptide fused or conjugated to at least one cell-penetrating peptide (CPP). Also provided by the invention are methods for treating a subject suffering from lysosomal storage disorders (LSD). | 09-02-2010 |
| 20090186802 | Cell Penetrating Peptide Conjugates for Delivering of Nucleic Acids into a Cell - The invention provides cell penetrating peptide-nucleic acid conjugates having the formula P-L-N, wherein P is a cell penetrating peptide, N is a nucleic acid, preferably an oligonucleotide and more preferably a siRNA, and L is a hydrophilic polymer, preferably a polyethylene glycol (PEG)-based linker linking P and N together. Compositions, methods of use and methods for producing such conjugates are also disclosed. | 07-23-2009 |
