| Devgen NV Patent applications |
| Patent application number | Title | Published |
| 20100170000 | Rna constructs - The present invention concerns concatemer and/or stabilized RNA constructs capable of forming dsRNA, optionally comprising a sequence capable of protecting the dsRNA against RNA processing in a host cell. The invention also relates to methods of producing these constructs and to methods for using these constructs. The constructs according to the present invention are particularly useful in plant pest control. | 07-01-2010 |
| 20100168102 | Amide Derivatives as Kinase Inhibitors - The present invention relates to new AGC kinase inhibitors, in particular to compounds of Formula (I) or (II) or a stereoisomer tautomer, racemic, metabolite, pro- or predrug, salt, hydrate, or solvate thereof, wherein Ar | 07-01-2010 |
| 20100068172 | Nematode Control - The present invention concerns methods for controlling nematode infestation via dsRNA mediated gene silencing, whereby the intact nematodes are contacted with a double-stranded RNA and whereby the double-stranded RNA is taken up by the intact nematodes. In one particular embodiment, the methods of the invention are used to alleviate plants from nematode pests. Alternatively, the methods are used for treating and/or preventing nematode infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable nematode target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed. | 03-18-2010 |
| 20100011654 | RNAI FOR THE CONTROL OF INSECTS AND ARACHNIDS - The present invention describes a new non-compound based approach for insect and/or arachnid control. The present inventors have identified for the first time novel targets for RNAi, which can effectively control insect and/or arachnid pest populations. Accordingly, the invention provides both nucleotide and amino acid sequences for the novel targets. Also provided are RNA constructs including double stranded RNA regions for mediating RNAi in insects, DNA constructs, expression vectors, host cells and compositions for controlling insects and/or arachnids using RNAi. Finally, the invention also provides for the use of the constructs, vectors, host cells and compositions in control of insects and/or arachnids populations and suitable kits for use in an RNAi based method of controlling insect and/or arachnid pests. | 01-21-2010 |
| 20090298787 | Dsrna as Insect Control Agent - The present invention relates to methods for controlling pest infestation using double standard RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants. | 12-03-2009 |
| 20090285784 | DSRNA As Insect Control Agent - The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed. | 11-19-2009 |
| 20090263364 | Method and constructs for delivering double stranded rna to pest organisms - The present invention relates in generally to RNAi and its use in gene silencing. In particular, the present invention relates to methods and constructs for delivering double stranded RNA (dsRNA) to pest organisms. | 10-22-2009 |
| 20090238805 | METHODS AND COMPOSITIONS FOR INCREASING RNA INTERFERENCE - The present invention relates to compositions containing a combination of a first active component comprising one or more sulfated polysaccharides and/or glycosaminoglycans and a second active component comprising one or more RNAi-inducing molecules, and methods for using these compositions to enhance double-stranded RNA (dsRNA)-mediated gene silencing in pest or pathogen species. The invention further relates to methods for controlling pests or pathogens, methods for preventing pest infestations or pathogen infections and methods for knocking down gene expression in pests or pathogens using the compositions and methods of the invention. | 09-24-2009 |
| 20090209605 | NEMATICIDAL COMPOSITIONS - The present invention concerns nematicidal compounds, their formulation as nematicidal composition and their use for controlling nematodes, preferably plant parasitic nematodes. | 08-20-2009 |
| 20090126038 | Rna constructs - The present invention concerns concatemer and/or stabilized RNA constructs capable of forming dsRNA, optionally comprising a sequence capable of protecting the dsRNA against RNA processing in a host cell. The invention also relates to methods of producing these constructs and to methods for using these constructs. The constructs according to the present invention are particularly useful in plant pest control. | 05-14-2009 |
| 20090118283 | Amide Derivatives as Kinase Inhibitors - The present invention relates to new AGC kinase inhibitors, in particular to compounds of Formula (I) or (II) or a stereoisomer tautomer, racemic, metabolite, pro- or predrug, salt, hydrate, or solvate thereof, wherein Ar | 05-07-2009 |
| 20080317881 | METHOD FOR SUSTAINABLE TRANSGENE TRANSCRIPTION - The present invention relates to constructs and methods for improving expression of transgenes in plants, animals and humans. | 12-25-2008 |
| 20080241894 | VECTOR CONSTRUCTS - Improved vector constructs useful in the expression of double-stranded RNA are provided. The constructs are particularly useful for expression of double-stranded RNA in vitro and in vivo. | 10-02-2008 |