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Delenex Therapeutics AG

Shlieren, CH

Delenex Therapeutics AG Patent applications
Patent application numberTitlePublished
20110159008Antibodies Binding To The Extracellular Domain Of The Receptor Tyrosine Kinase ALK - The present invention concerns an antibody specific for human ALK (Anaplastic Lymphoma Kinase), in particular a scFv, a nucleic acid sequence encoding it, its production and its use as a pharmaceutical or for diagnostic purposes. Said antibody is suitable for the local treatment of tumors, in particular glioblastoma.06-30-2011
20110020220HUMANIZED ANTIBODIES AGAINST THE BETA-AMYLOID PEPTIDE - The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerisation of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody; (ii) Administering an effective dose of said antibody intranasally or systemically to a subject; and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.01-27-2011
20110002927ANTIGEN-BINDING POLYPEPTIDES AGAINST CARTILAGE DEGENERATION - The invention provides an antigen-binding polypeptide which is able to penetrate into the cartilage. The disclosed polypeptide, compositions and methods are suitable for the treatment, prevention and/or delay of progression of cartilage degeneration.01-06-2011