| DANISCO US INC. Patent applications |
| Patent application number | Title | Published |
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| 20120114948 | Granule With Reduced Dust Potential - A granule with an allergenic component has reduced dust by including antifoam added during the production of the granule. The antifoam may be dispersed throughout the granule or added to one of the components of the granule. The granule with antifoam produces at least 30% less dust than a comparable granule produced according to a process in which no antifoam is added. | 05-10-2012 |
| 20120094867 | High-Throughput Molecular Rotor Viscometry Assay - Described are compositions and methods related to determining the rate of viscosity change in a suspension in real time. The compositions and methods have a broad range of applications, including the measurement of amylase-mediated liquefaction of a starch suspension. | 04-19-2012 |
| 20120061610 | SUBSTANCE COMPOSITION AND METHOD FOR MELTING ICE AND PREVENTING SLIPPERINESS AND USE OF BETAINE FOR MELTING ICE AND PREVENTING SLIPPERINESS - The invention relates to a combination of compounds for de-icing and/or anti-skid treatment, which combination comprises betaine and at least one other de-icing agent, which has been selected from the group consisting of acetates, formates, area and combinations thereof. The invention also relates to a method of de-icing and/or anti-skid treatment, wherein a combination of compounds selected from the group consisting of acetates, formats, urea and combinations thereof, are applied to a slippery surface or a surface vulnerable to slipperiness. The invention further relates to the use of betaine for de-icing and/or anti-skid treatment, when betaine is used in combination with at least one ether de-icing agent, which has been selected from the group consisting of acetates, formates, urea and combinations thereof. | 03-15-2012 |
| 20120058527 | CAL A-RELATED ACYLTRANSFERASES AND METHODS OF USE, THEREOF - Compositions and methods relating to lipase/acyltransferase enzymes identified in prokaryotes and eukaryotes are described. These enzymes can be used in such applications as lipid stain removal from fabrics and hard surfaces and chemical synthesis reactions. | 03-08-2012 |
| 20120045822 | Cleaning System Comprising An Alpha-Amylase And A Protease - Described are compositions and methods involving a | 02-23-2012 |
| 20120045812 | PRODUCTION OF ISOPRENE UNDER NEUTRAL pH CONDITIONS - Embodiments of the present disclosure relate to a process for producing isoprene from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process. | 02-23-2012 |
| 20120045811 | EGVII Endoglucanase and Nucleic Acids Encoding the Same - The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same. | 02-23-2012 |
| 20120040435 | Novel Variant Hypocrea Jecorina CBH2 Cellulases - Described herein are variants of | 02-16-2012 |
| 20120036649 | ENZYMATIC TEXTILE BLEACHING COMPOSITIONS AND METHODS OF USE THEREOF - Described are compositions and methods for enzymatic bleaching of textiles. A perhydrolase enzyme is used in combination with an ester substrate and hydrogen peroxide to produce a peracid for textile bleaching. Textiles bleached by the methods herein exhibit increased dye uptake, decreased textile damage, and/or bulkier softer handle than textiles bleached by conventional chemical bleaching processes. | 02-16-2012 |
| 20120034659 | NEUTRAL pH SACCHARIFICATION AND FERMENTATION - Embodiments of the present disclosure relate to a process for producing downstream products, such as fermentable sugars and end products, from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process. | 02-09-2012 |
| 20120028318 | FUNGAL CUTINASE FROM MAGNAPORTHE GRISEA - Described are compositions and methods relating to a fungal cutinase cloned from | 02-02-2012 |
| 20120024783 | Oxidative Decolorization Of Dyes With Enzymatically Generated Peracid Method, Composition And Kit Of Parts - Described are compositions and methods for the decolorization of dye molecules in an aqueous medium using enzymatically-generated peracid. | 02-02-2012 |
| 20120021485 | HYBRID ALPHA-AMYLASES - Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like ?-amylase, e.g., a | 01-26-2012 |
| 20120015849 | Method of Creating a Library of Bacterial Clones with Varying Levels of Gene Expression - The present invention relates to a method of creating DNA libraries that include an artificial promoter library and/or a modified ribosome binding site library and transforming bacterial host cells with the library to obtain a population of bacterial clones having a range of expression levels for a chromosomal gene of interest. | 01-19-2012 |
| 20120009651 | Production of Thermolysin and Variants Thereof and Use In Liquid Detergents - The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation. | 01-12-2012 |
| 20120009635 | Metabolically Engineered Bacterial Strains Having Non-Functional Endogenous Gluconate Transporters - The present invention relates to engineering metabolic pathways in bacterial host cells which results in enhanced carbon flow for the production of ascorbic acid (ASA) intermediates. In particular, the invention relates to increasing the production of ASA intermediates in bacterial cells by enhancing the availability of gluconate resulting from the inactivation of endogenous gluconate transporter genes. | 01-12-2012 |
| 20120003718 | Protease Comprising One Or More Combinable Mutations - The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided. | 01-05-2012 |
| 20110312064 | METHODS OF REMOVING OILY STAINS FROM FABRICS - Described are compositions and methods for removing oily stains from fabrics by treating the fabrics with cyclodextrins. Cyclodextrins can be added to the fabrics or generated in situ by converting a substrate of starch or dextrin with cyclomaltodextrin glucanotransferase. | 12-22-2011 |
| 20110312031 | TRICHODERMA PROMOTER - A promoter for use in producing proteins in filamentous fungal host cells is provided. In one embodiment, the promoter comprises SEQ ID NO:1, or a variant or a truncated form thereof that has promoter activity in a host cell. Also provided are recombinant nucleic acids, vectors containing the promoter and host cells containing a recombinant nucleic acid or vector. Methods of producing a protein using the host cells are also provided. | 12-22-2011 |
| 20110302722 | LACCASES AND METHODS OF USE THEREOF AT LOW TEMPERATURE - Laccase enzymes and nucleic acid sequences encoding such laccase enzymes are described. The laccase enzymes may be employed in conjunction with mediators in improved methods for modifying the color of denim fabrics. Low temperature and single-bath textile processing using laccase enzymes are also described. | 12-15-2011 |
| 20110300201 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE - The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a water-soluble polymeric matrix and a substrate for the enzyme in a carrier liquid in which the polymeric matrix is insoluble. When water is added, the polymeric matrix is solubilized and enzyme is released from the matrix, permitting catalytic action upon the substrate. | 12-08-2011 |
| 20110294191 | INCREASED PRODUCTION OF ASPARTIC PROTEASES IN FILAMENTOUS FUNGAL CELLS - Described are compositions and methods relating to filamentous fungal cells genetically engineered to provide increased production of aspartic proteases, such as PEPAa, PEPAb, PEPAc, and PEPAd. Also described are nucleic acids and methods for making the engineered filamentous fungal cells. | 12-01-2011 |
| 20110287511 | Novel Trichoderma Genes - Described herein are novel gene sequences isolated from | 11-24-2011 |
| 20110281328 | Compositions and Methods Comprising A Subtilisin Variant - The present invention provides a | 11-17-2011 |
| 20110281327 | Compositions And Methods Comprising Variant Proteases - The present invention provides variant proteases, compositions comprising such variant proteases, and methods of cleaning comprising such variant proteases. | 11-17-2011 |
| 20110281326 | PULLULANASE VARIANTS WITH INCREASED PRODUCTIVITY - The invention relates to novel variants of the enzymatic peptide pullulanase, the gene sequences encoding said novel peptides, expression vectors comprising those gene sequences as well as organisms expressing the novel pullulanase variants. The novel pullulanase variants of the present invention were made empirically by the use of codon-optimization procedures, selective truncation of “wild-type” molecules and through the replacement of selected amino acid residues. Furthermore, the invention relates to the use of these novel pullulanase peptides in the textile, fermentation, food and other industries. | 11-17-2011 |
| 20110281325 | LIPOLYTIC ENZYME LIP1 - The present invention provides a novel nucleic acid sequence, designated LIP1, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same. | 11-17-2011 |
| 20110281324 | Enzymes With Lipase Activity - Described are detergent compositions comprising at least one lipase enzyme selected from SriII, ScoIIA, ScoIIB, CefII, and variants, thereof. The compositions are useful for removing oily stains from fabric. | 11-17-2011 |
| 20110269210 | ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES - Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and that exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions generally comprise at least one of an additional enzyme, a detergent,.a surfactant, a chelator, an oxidizing agent, an acidulant, an alkalizing agent, a source of peroxide, a source of hardness, a salt, a detergent complexing agent, a polymer, a stabilizing agent, or a fabric conditioner. Also disclosed are detergent formulations comprising the variants. Methods of using the compositions for desizing woven material and washing or cleaning items, such as dishes or laundry, are disclosed. Kits related thereto are also provided. | 11-03-2011 |
| 20110263517 | Cytokines and Cytokine Receptors with Reduced Immunogenicity - The present invention provides methods for the identification of CD4+ T-cell epitopes in the sequences of various proteins, namely, human cytokines and cytokine receptors, as well as the production of peptides which when incorporated into the protein sequence, are no longer capable of initiating the CD4+ T-cell response. In some embodiments, the present invention provides means and compositions suitable for reducing the immunogenicity of cytokines and cytokines receptors such as interferon-β, soluble tumor necrosis factor receptor-1, erythoropoietin, and thrombopoietin. | 10-27-2011 |
| 20110262999 | Compositions and Methods Comprising Protease Variants - The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions. | 10-27-2011 |
| 20110262996 | METHODS AND MATERIALS FOR DEGRADING PYRETHROID - Methods and compositions are provided for enzymatic detoxification of pyrethroid such as permethrin. The methods involve application of compositions of organophosphorus hydrolase OPH to surfaces or substances contaminated with pyrethroid such as permethrin. | 10-27-2011 |
| 20110262953 | Phosphate Limited Inducible Promoter and A Bacillus Expression System - An evolvable production strain of | 10-27-2011 |
| 20110262419 | SPECIFICALLY TARGETED CATALYTIC ANTAGONISTS AND USES THEREOF - This invention provides chimeric molecules that are catalytic antagonists of a target molecule. The catalytic antagonists of this invention preferably comprise a targeting moiety attached to an enzyme that degrades the molecule specifically bound by the targeting moiety. The catalytic antagonists of this invention thus bind to a target recognized by the targeting moiety (e.g., a receptor) the enzyme component of the chimera then degrades all or part of the target. This typically results in a reduction or loss of activity of the target and release of the chimeric molecule. The chimeric molecule is then free to attack and degrade another target molecule. | 10-27-2011 |
| 20110256608 | Modified Variant Bowman Birk Protease Inhibitors - The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care. | 10-20-2011 |
| 20110251116 | MULTIPLE MUTATION VARIANTS OF SERINE PROTEASE - The present invention provides novel | 10-13-2011 |
| 20110244526 | ALPHA-AMYLASE BLENDS AND METHODS FOR USING SAID BLENDS - The present invention relates to an alpha-amylase blend, including a | 10-06-2011 |
| 20110229956 | Novel Variant Hyprocrea Jecorina CBH1 Cellulases - Described herein are variants of | 09-22-2011 |
| 20110229943 | METHODS FOR CONVERTING GLUCOSE TO ASCORBIC ACID - Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. | 09-22-2011 |
| 20110212505 | BGL3 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same. | 09-01-2011 |
| 20110201535 | Expression of Streptomyces Subtilisin Inhibitor (SSI) Proteins In Bacillus and Streptomyces sp. | 08-18-2011 |
| 20110195059 | Enzymatic Prevention and Control of Biofilm - The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm. | 08-11-2011 |
| 20110183401 | Kappa-Carrageenase And Kappa-Carrageenase-Containing Compositions - The present invention provides cleaning compositions comprising at least one carrageenase enzyme, methods for producing carrageenase enzymes in host cells, host cells comprising recombinant polynucleotides encoding at least one carrageenase, and recombinant polynucleotides encoding carrageenase. | 07-28-2011 |
| 20110177561 | Novel CBH1 Homologs And Varian CBH1 Cellulase - Disclosed are a number of homologs and variants of | 07-21-2011 |
| 20110171718 | Proteases With Modified Pre-Pro Regions - The invention relates to modified polynucleotides encoding modified proteases, and methods for altering the production of proteases in microorganisms. In particular, the modified polynucleotides comprise one or more mutations that encode modified proteases having modifications of the pre-pro region that enhance the production of the active enzyme. The present invention further relates to methods for altering the production of proteases in microorganisms, such as | 07-14-2011 |
| 20110159557 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE - Provided herein are improved compositions and methods for the increased production of isoprene. Also provided herein are improved compositions and methods for the increased production of heterologous polypeptides capable of biological activity. | 06-30-2011 |
| 20110154581 | POLYOL OXIDASES - The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting. | 06-30-2011 |
| 20110136182 | SWOLLENIN COMPOSITIONS AND METHODS OF INCREASING THE EFFICIENCY OF A CELLULASE - Described are compositions and methods relating to enhancing the efficiency of cellulases for sugar production from cellulosic biomass using the polypeptide swollenin. | 06-09-2011 |
| 20110117598 | Enhanced Protein Production in Bacillus - The present invention relates to cells that have been genetically manipulated to have an altered capacity to express and/or produce proteins of interest. In particular, the present invention relates to modified host cells of Gram-positive microorganisms, such as | 05-19-2011 |
| 20110110912 | STORAGE-STABLE GLUCOSE OXIDASE - The present invention provides methods and compositions comprising at least one glucose oxidase enzyme, wherein the glucose oxidase has improved storage stability. In some preferred embodiments, the glucose oxidase enzyme is stable after exposure to elevated temperatures. In some alternative preferred embodiments, the glucose oxidase has improved storage stability in liquid formulations. In some particularly preferred embodiments, the present invention provides methods and compositions comprising glucose oxidase(s) obtained from | 05-12-2011 |
| 20110091959 | Multiply-Substituted Protease Variants - Novel enzyme variants including protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 27, 45, 170, 181, 251 and 271 of | 04-21-2011 |
| 20110091958 | Multiply-Substituted Protease Variants - Novel enzyme variants including protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 27, 45, 170, 181, 251 and 271 of | 04-21-2011 |
| 20110086412 | Multiply-Substituted Protease Variants - Novel enzyme variants including protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 27, 45, 170, 181, 251 and 271 of | 04-14-2011 |
| 20110086408 | Hemicellulase Enriched Compositions for Enhancing Hydrolysis of Biomass - Described are compositions and methods relating to cellulase/hemicellulase enzyme blends for improving the enzymatic hydrolysis of cellulosic and hemicellulosic materials, as commonly found in biomass | 04-14-2011 |
| 20110082048 | Systematic Evaluation of Sequence and Activity Relationships Using Site Evaluation Libraries For Engineering Multiple Properties - The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. | 04-07-2011 |
| 20110045571 | Proteases With Modified Pro Regions - The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. | 02-24-2011 |
| 20100221780 | Modified Variant Bowman Birk Protease Inhibitors - The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care. | 09-02-2010 |
| 20100041104 | Compositions and Methods Comprising Cellulase Variants with Reduced Affinity to Non-Cellulosic Materials - The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions. | 02-18-2010 |
| 20090121177 | SUBSTANCE COMPOSITION AND METHOD FOR MELTING ICE AND PREVENTING SLIPPERINESS AND USE OF BETAINE FOR MELTING ICE AND PREVENTING SLIPPERINESS - The invention relates to a combination of compounds for de-icing and/or anti-skid treatment, which combination comprises betaine and at least one other de-icing agent, which has been selected from the group consisting of acetates, formates, urea and combinations thereof. The invention also relates to a method of de-icing and/or anti- skid treatment, wherein a combination of compounds selected from the group consisting of acetates, formats, urea and combinations thereof, are applied to a slippery surface or a surface vulnerable to slipperiness. The invention further relates to the use of betaine for de-icing and/or anti-skid treatment, when betaine is used in combination with at least one other de-icing agent, which has been selected from the group consisting of acetates, formates, urea and combinations thereof. | 05-14-2009 |
