| CRYOLIFE, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120010725 | Tissue Implants for Implantation and Methods for Preparing the Same - A method is provided for preparing a tissue implant for implantation. The method includes treating a pericardium tissue material, which has been harvested from a donor and rendered essentially acellular, with a chlorine dioxide treatment solution; and thereafter treating the pericardium tissue material with an antioxidant solution, which comprises ascorbic acid or a salt thereof. | 01-12-2012 |
| 20120009679 | Tissue Implants for Implantation and Methods for Preparing the Same - A method is provided for preparing a tissue implant for implantation. The method includes harvesting a tissue material from a human or an animal donor, treating the tissue material in a nuclease-containing solution, and thereafter treating the tissue material with an alkaline alcohol solution. The nuclease-containing solution includes an antimicrobial. The alkaline alcohol solution comprises sodium hydroxide and ethanol. | 01-12-2012 |
| 20120009644 | Tissue Implants for Implantation and Methods for Preparing the Same - A method is provided for preparing a tissue implant for implantation. The method includes harvesting a tissue material from a human or an animal donor, treating the tissue material with water or a hypotonic solution to lyse native cells of the tissue material, treating the tissue material in a nuclease-containing solution which includes an antimicrobial, treating the tissue material with an alkaline alcohol solution, treating the tissue material with a chlorine dioxide treatment solution, and sterilizing the tissue material. | 01-12-2012 |
| 20110208238 | APPLICATOR DELIVERY TIP EXTENSION - A delivery tip extension communicates an adhesive material from a fluid applicator tip to a site within a patient. The delivery tip extension has an elongated shaft with a proximal end portion, a central body portion, and a tapered distal end portion. The central body portion has a length between about 5 cm and about 45 cm. A lumen is defined within and extends along the elongated shaft from a proximal opening to a distal opening. The elongated shaft is relatively more rigid along the central body portion than along the distal end portion to facilitate driving the elongated shaft through the patient with reduced trauma to the patient by the distal end portion. The lumen is sized and shaped along the proximal end portion for securely receiving the fluid applicator tip inserted through the proximal opening such that a dispensing outlet on the fluid applicator tip is in fluid communication with the lumen. The delivery tip extension is sterilized or sterilizable. | 08-25-2011 |
| 20100285587 | Tissue Graft - A method of preparing a tissue graft material is disclosed. The disclosure also relates to a multipurpose tissue graft material and to methods of using same as a replacement for vascular and non-vascular tissue. | 11-11-2010 |
| 20100233669 | BIOBURDEN-REDUCING ANTIBIOTIC COMPOSITION AND METHOD OF USE - An antibiotic composition is provided for use in decontaminating biological tissue, for example, graft tissues for transplantation or preparation for terminal sterilization. The antibiotic composition is a physiological solution includes a lantibiotic, such as nisin. The antibiotic solution is effective to substantially inhibit bacterial growth of at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue. The method may include contacting the tissue with the antimicrobial composition at a temperature and for a period of time effective to substantially inhibit bacterial growth of the at least one type of gram-positive bacteria while substantially maintaining the physiological characteristics of the tissue. | 09-16-2010 |
