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CRC FOR ASTHMA AND AIRWAYS LTD

CRC FOR ASTHMA AND AIRWAYS LTD Patent applications
Patent application numberTitlePublished
20110129845METHOD OF DIAGNOSIS - The present invention relates generally to a method of diagnosing, predicting and/or monitoring the development or progress of an airway tissue inflammatory response in a mammal. More particularly, the present invention relates to a method of diagnosing, predicting and/or monitoring the development or progress of an airway tissue inflammatory response by analysis of activin and/or follistatin levels in the breath condensate of said mammal. The present invention further provides a method for predicting, diagnosing and/or monitoring conditions associated with or characterised by the onset of an airway tissue inflammatory response. Also provided are diagnostic agents useful for detecting activin expression levels.06-02-2011
20110028408 DIAGNOSTIC MOLECULE AND THERAPEUTIC TARGET - Provided herein are methods and compositions for regulating airway tissue remodelling and for treating or preventing conditions associated with airway inflammation and/or airway tissue remodelling. The methods comprise normalising fibulin-1 levels in said tissue relative to normal endogenous levels. In an embodiment the methods comprise administering to a subject in need thereof an effective amount of at least one agent capable of inhibiting the expression and/or activity of fibulin-1.02-03-2011
20100297135EPITOPE FOR NEUTRALIZING ANTIBODIES - Provided herein are immunogenic peptides of GM-CSF comprising an amino acid sequence set forth in any one of SEQ ID NOs:2 to 6, or a portion thereof, and compounds and molecules that specifically interact with or bind to a region of GM-CSF located between, or corresponding to a region located between, about residues 89 and 117 of the human GM-CSF polypeptide sequence as set forth in SEQ NO:1.11-25-2010