COSMA S.P.A.
COSMA S.P.A. Patent applications | ||
Patent application number | Title | Published |
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20140343322 | PROCESS FOR PREPARING LEVOMILNACIPRAN HCL - The invention relates to one-pot process for preparing (1S,2R)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-aminomethylcyclopropane of formula (I) comprising the step of reacting (1S,2R)-N,N-diethyl-2-(hydroxymethyl)-1-phenylcyclopropanecarboxamide successively with the following reactants 1) triethyl orthoformate and methanesulfonic acid or triethylamine and methanesulfonyl chloride, 2) a phthalimidating agent, 3) aqueous EtNH | 11-20-2014 |