| Core Dynamics Limited Patent applications |
| Patent application number | Title | Published |
|---|
| 20120090160 | METHOD AND APPARATUS FOR FREEZING OF A BIOLOGICAL MATERIAL - Provided is a method of designing a system for use in a process for freezing a biological material at a desired cooling rate, the system including a device for freezing biological material including a cooling unit and a heat insulation unit, and a container configured for receiving therein the biological material; the method including: designing the container to have a first portion and a second portion; designing the heat insulation unit to have a first receiving portion and a second receiving portion; configuring the first and second portions of the heat insulation unit to receive therein the first and second portions of the container, respectively, to ensure that the second portion of the container is in thermal contact with the cooling unit; determining dimensions of the first and second portions of the container and of the heat insulation unit in accordance with the desired cooling rate. | 04-19-2012 |
| 20110177488 | BIOLOGICAL MATERIAL AND METHODS AND SOLUTIONS FOR PRESERVATION THEREOF - Provided is a preservation solution for preserving biological material at low temperature including one or more polyphenols and a method for preservation of biological material, the method includes adding the preservation solution to biological material, cooling the biological material and storing it under appropriate storing conditions. The present method may be used for hypothermic preservation or for cryopreservation, including freezing and lyophilization, and may be used with any biological material, including cells selected from RBC, WBC, MNC, UCB MNC and bacteria. In the case of RBC, also disclosed is a method for its freezing such that upon thawing, the material has less than 2% free hemoglobin. | 07-21-2011 |
| 20100281886 | SYSTEMS, DEVICES AND METHODS FOR FREEZING AND THAWING BIOLOGICAL MATERIALS - There are provided a system and a method for cryopreserving a liquid biological material disposed in a bag having a longitudinal axis. The system comprises a bag holder for holding the bag, so that the biological material therein has a surface area S, and a volume V, a tank containing a cryogenic fluid, a mechanism for the immersion of the bag holder into the tank along the longitudinal axis, an opening in the tank for insertion therethrough of the bag holder, and a guide member extending from the opening into the tank. There are further provided a system and a method for warming a cryopreserved liquid biological material disposed in a bag. The system comprises a heat source, a warming device having a space for placing the bag therein, connected to the heat source and adapted to transfer heat from the heat source to the bag, and means for maintaining the heat source in heat transfer contact with a cryogenically preserved portion of the material to allow receiving the heat by said cryogenically preserved portion. | 11-11-2010 |
| 20100197017 | METHOD FOR STERILIZATION OF BIOLOGICAL PREPARATIONS - Provided is a method for the sterilization of a biological preparation including desired viable biological entities. The method includes irradiating a dried (e.g. freeze-dried) biological preparation with UV radiation at an intensity and for a duration sufficient to reduce the amount or activity of living-matter contaminants in the biological preparation, the intensity and duration selected such that at least part of the desired biological entities in the sample remains viable. The described method is particularly suitable for the reduction of the amount or activity of contaminants such as bacteria or viruses from biological preparations including red blood cells or platelets. | 08-05-2010 |
| 20100105133 | Somatic Cells for Use in Cell Therapy - The present invention generally concerns cell therapy and products for use in such therapy. Particularly, the invention provides a preserved cell preparation essentially free of one or more members of a group of cryoprotecting agents consisting of polyalcohols, DMSO and cryoprotecting proteins, the preserved cell preparation comprising somatic cells and at least one polyphenol, wherein upon reconstitution of cells in the cell preparation, at least a portion of said stem cells are viable, said portion being sufficient for use of the cell preparation in stem cell therapy. The invention also provides cells reconstituted from preserved somatic cells, and the use of the reconstituted cells in cell therapy. A preferred cell preparation in accordance with the invention comprises stem cells, preferably human stem cells. | 04-29-2010 |
