| China Medical University Patent applications |
| Patent application number | Title | Published |
|---|
| 20130102602 | 2-Aryl-4-Quinazolinones And Their Pharmaceutical Compositions - Provided is a compound of the formula I or a pharmaceutically acceptable salt, solvate or stereoisomer thereof: | 04-25-2013 |
| 20130072452 | PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION - A pharmaceutical composition for inhibiting inflammation is provided. The pharmaceutical composition comprises (a) hyaluronic acid, (b) a vitamin and (c) a pharmaceutically acceptable carrier. | 03-21-2013 |
| 20130053449 | METHOD FOR INHIBITING HISTONE GENE TRANSCRIPTION AND EXPRESSION - A method for inhibiting at least one of histone gene transcription and histone expression in a subject is provided. The method comprises administrating to the subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: | 02-28-2013 |
| 20130023643 | NUCLEAR LOCALIZATION SIGNAL PEPTIDES DERIVED FROM VP2 PROTEIN OF CHICKEN ANEMIA VIRUS AND USES OF SAID PEPTIDES - Disclosed herein are isolated peptides having nuclear localization activity and derived from the VP2 protein of chicken anemia virus (CAV). The isolated peptides are proven to be useful and effective in the nuclear delivery of a selected target substance, such as proteins, peptides, nucleic acids, pharmaceutically active agents, chemical substances, etc. The isolated peptide can transport a target substance, in particular a protein, into the nucleus of a mammalian cell by forming a conjugate with the target substance, or via an expression cassette capable of expressing a fusion protein having the isolated peptide and the target protein. | 01-24-2013 |
| 20130023036 | NUCLEIC ACID CONSTRUCT, RECOMBINANT VECTOR, AND RECOMBINANT E. COLI PRODUCING CHICKEN ANEMIA VIRUS VP1 PROTEIN - Disclosed herein is an expression cassette adapted to be expressed in an | 01-24-2013 |
| 20120322082 | BIOMARKER FOR AMYOTROPHIC LATERAL SCLEROSIS AND DIAGNOSTIC KIT AND METHOD USED THEREOF - A diagnostic marker for determining of a patient with amyotrophic lateral sclerosis (ALS), comprising an autoantibody against a human protein HMGB1 is described. A diagnostic kit for determining of a patient with ALS, comprising: (a) an HMGB1 protein; and (b) an HMGB1 antibody standard is also presented. A method of determining ALS in a subject, comprising the steps: (a) detecting autoantibody against HMGB1 in a biological sample taken from the subject and normal control individuals; and (b) statistically comparing concentrations of the autoantibody against HMGB1 in the subject with that of the normal control individuals obtained from step (a); wherein a higher concentration of the autoantibody against HMGB1 in the subject than a cut-off concentration indicates the subject suffers from ALS is further described. | 12-20-2012 |
| 20120283200 | PHARMACEUTICAL COMPOSITION AND METHOD FOR PREVENTING OR TREATING CHRONIC HEART DISEASE - The present invention provides a pharmaceutical composition for preventing or treating a chronic heart disease, comprising a compound of a formula (I): | 11-08-2012 |
| 20120277182 | ANOECTOCHILUS SPP. POLYSACCHARIDE EXTRACTS FOR STIMULATING GROWTH OF ADVANTAGEOUS BACTERIA, STIMULATING RELEASE OF GRANULOCYTE COLONY-STIMULATING FACTOR, MODULATING T HELPER CELL TYPE I, AND/OR MODULATING T HELPER CELL TYPE II AND USES OF THE SAME | 11-01-2012 |
| 20120238513 | METHOD FOR INHIBITING ACTIVATION OF MACROPHAGES - Provided is a method for inhibiting the activation of macrophages in a subject, comprising administrating to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable ester of the compound, and combinations thereof: | 09-20-2012 |
| 20120231063 | DRESSING COMPRISING ACTIVE COMPONENTS OF CENTELLA ASIATICA AND USE OF THE SAME - Provided is a dressing, comprising (a) a substrate layer and (b) an active layer, which is a nanofiber layer and comprises: (b1) at least one of gelatin and collagen; (b2) polyvinyl alcohol (PVA); and (b3) at least one of asiaticoside and a | 09-13-2012 |
| 20120208875 | METHOD FOR INHIBITING BLOOD VESSEL STENOSIS - Provided is a method for inhibiting blood vessel stenosis in a subject, comprising administrating to the subject an effective amount of an active ingredient selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof. Also provided is a method for inhibiting blood vessel stenosis in a subject, comprising administration to the subject an effective amount of an | 08-16-2012 |
| 20120178803 | METHOD FOR TREATING BRAIN CANCER OR REDUCING TEMOZOLOMIDE-RESISTANCE OF BRAIN CANCER CELLS - Provided is a method for treating brain cancer or reducing temozolomide-resistance of brain cancer cells in a subject, comprising administrating to the subject an effective amount of an active ingredient selected from the group consisting of (Z)-butylidenephthalide of formula (I), a pharmaceutically acceptable salt of (Z)-butylidenephthalide, a pharmaceutically acceptable ester of (Z)-butylidenephthalide, and combinations thereof: | 07-12-2012 |
| 20120164250 | METHOD FOR ANTI-OXIDATION, INHIBITING ACTIVITY AND/OR EXPRESSION OF MATRIX METALLOPROTEINASE, AND/OR INHIBITING PHOSPORYLATION OF MITOGEN-ACTIVATED PROTEIN KINASE USING FLEMINGIA MACROPHYLLA EXTRACT - A method for inhibiting at least one selected from the group consisting of oxidation, the activity of matrix metalloproteinase (MMP), the expression of matrix metalloproteinase, and the phosphorylation of mitogen-activated protein kinase (MAP kinase) in a mammal, comprising administrating to the mammal an effective amount of a | 06-28-2012 |
| 20120120394 | MICROSCANNING SYSTEM AND RELATED METHOD - A microscanning system including a microscope, a relay lens device, a stepping motor and a hyper-spectrometer is disclosed. The microscope is adapted to acquire and enlarge an image of an object to generate an enlarged image which is a 2D image distributed along the first direction and second direction. The relay lenses device disposed behind the microscope receives and transfers the enlarged image outputted by the microscope. The stepping motor electrically connected to the relay lens device reciprocates the relay lens linearly in the first direction device in a stepwise manner along the second direction. . The hyper-spectrometer disposed behind the rely lens device receives the partial enlarged images of the object along the first direction that are transferred by the relay lens device sequentially along the second direction, and transform the partially enlarged images into the corresponding spectrum information. | 05-17-2012 |
| 20120108536 | PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION - A pharmaceutical composition for inhibiting inflammation, comprising (a) hyaluronic acid, (b) a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, and (c) a pharmaceutically acceptable carrier, is provided. Also provided is a method for inhibiting inflammation in a mammal, comprising administrating to the mammal an effective amount of a composition comprising (a) hyaluronic acid and (b) an HMG-CoA reductase inhibitor. | 05-03-2012 |
| 20120064145 | WOUND DRESSING - The present invention discloses a wound dressing which may be a double-layer wound dressing, comprising a polymer material layer in combination with anti-infective antibiotics or anti-infective Chinese herb medicine at the upper layer of the wound dressing, and a porous carbon material layer capable of loading with skin-associated epithelial cells at the lower layer of the wound dressing. The wound dressing with the antibiotics can block effectively the invasion of bacteria in the external environment, thereby preventing the wound from secondary infection. While covering the wound site, the porous carbon material layer with the epithelial cells can thus provide the healthy epithelial cells and attract the surrounding healthy cells to aggregate for secreting collagen so as to promote the wound healing process. According to the present invention, there is an obviously enhancing effect on wound tissue regeneration, restoration and healing, and there is a grant development potential in clinical applications. | 03-15-2012 |
| 20120027676 | MODIFIED SODIUM IODIDE SYMPORTER PROTEINS AND USES THEREOF - A modified sodium iodide symporter (NIS) protein is provided. The modified NIS protein comprises an amino acid sequence of SEQ ID NO.1 with the proviso that at least one amino acid residue within SEQ ID NO. 1 is changed. The modified NIS protein has an enhanced transport function, and the expression of the modified NIS protein in the cells results in higher intracellular levels of a substrate of a NIS protein than does the expression of the same amount of a wild-type NIS protein. | 02-02-2012 |
| 20120022008 | Compounds and Method for Inhibiting the Activity of Gelatinase and Collagenase - Compounds extracted from | 01-26-2012 |
| 20120020943 | Lactobacillus Plantarum and Uses Thereof - Provided is an isolated | 01-26-2012 |
| 20120017907 | Modified Liquid Trap Cup and a Liquid Trap Assembly - A liquid trap cup is provided. The liquid trap cup comprises a hollow cup tube with a upper portion and a lower portion, a piston element with a top portion and a tail portion and a liquid discharge structure, in which the piston element is arranged airtight in the lower portion and is movable between a start point and an end point of the lower portion so as to control the opening and the closing of the liquid discharge structure. | 01-26-2012 |
| 20110300536 | GENE MARKER AND METHOD FOR DETECTION OF ORAL CANCER - A gene marker for the detection of oral cancer, comprising methylated CpG sites in target genes, is provided. The CpG sites in the target genes are selected from a group consisting of the following CpG sites: FLT4_E206_F, ASCL1_E24_F, KDR_E79_F, TFPI2_P9_F, TERT_E20_F, ADCYAP1_P455_R, MT1A_P49_R, and combinations thereof. A method for the detection of oral cancer, comprising the following steps is also provided: a) providing a sample to be examined from an individual; b) detecting a methylation state of at least one CpG site in a target gene on the genomic DNA from cells of the sample, wherein the CpG site in the target gene is selected from a group consisting of the following CpG sites: FLT4_E206_F, ASCL1_E24_F, KDR_E79_F, TFPI2_P9_F, TERT_E20_F, ADCYAP1_P | 12-08-2011 |
| 20110281991 | CORE-SHELL METAL NANOPARTICLES AND METHOD FOR MANUFACTURING THE SAME - A method for manufacturing core-shell metal nanoparticles is provided. The method comprises providing a first solution containing a metal ion; providing a second solution containing Arabinogalactan and having a pH value ranging from about 1 to about 13; mixing the first solution and the second solution to form a third solution; and enabling the third solution to perform an oxidation-reduction reaction to form the core-shell metal nanoparticles. The core-shell metal nanoparticles comprise a core composed of metal; and a shell, composed of Arabinogalactan, covering the surface of he core. | 11-17-2011 |
| 20110278497 | NANOMETAL DISPERSION AND METHOD FOR PREPARING THE SAME - A nanometal dispersion and a method for preparing a nanometal dispersion are provided. The method comprises mixing a metal seed crystal aqueous solution, a polysaccharide aqueous solution, and a metal compound aqueous solution, followed by allowing the resulting mixture to conduct a reduction-oxidation reaction to form a nanometal. The produced nanometal dispersion comprises a polysaccharide and a nanometal. The polysaccharide is composed of N-actyl-D-glucosamine and glucuronic acid, and the nanometal has multimorphology. | 11-17-2011 |
| 20110183014 | PRODUCT CONTAINING EXTRACT FROM ZANTHOXYLUM AVICENNAE (LAM.) DC., AND PREPARATION PROCESS AND USE THEREOF - Disclosed herein are a product containing an extract from | 07-28-2011 |
| 20110178171 | COMPOUNDS FOR CANCER THERAPY - A method of inhibiting the cellular proliferation of at least one selected from the group consisting of androgen dependent prostate cancer cells, androgen independent prostate cancer cells, oral cancer cells, liver cancer cells (hepatoma), and gastric cancer cells in a subject is provided, wherein the method comprises administrating to the subject an effective amount of an active component selected from the group consisting of Z form isochaihulactone (Z-K8) of the following formula (I), E form isochaihulactone (E-K8) of the following formula (II), a pharmaceutically acceptable salt of Z-K8 or E-K8, a pharmaceutically acceptable ester of Z-K8 or E-K8, and combinations thereof: | 07-21-2011 |
| 20110172579 | INFLATION TYPE CERVICAL VERTEBRAE REHABILITATION DEVICE AND METHOD FOR USING THE SAME - An inflation type cervical vertebrae rehabilitation device includes at least one cervical vertebrae cell, a head cell connected to the at least one cervical vertebrae cell, an electric inflation portion and a control portion. The method includes a preparing step, a setting inflation processes step, an inflating step, and a completion step. One or more cervical vertebrae cells are inflatable and positioned between a support position and an operation position to support and rehabilitate the user's neck. The head cell is provided to support the user's head. So, the cervical vertebrae cells can support the user's head and neck with rehabilitation functions. The head cell is an auxiliary for support the user's head. It is easy to carry. This invention could be remote controlled. It contains the far infra-red heating function. In addition, there is a pose balance feature. | 07-14-2011 |
| 20110172578 | PLANTAR FASCIITIS REHABILITATION CONTROLLING DEVICE - The present invention relates to a plantar fasciitis rehabilitation controlling device. It mainly comprises a securing portion, a rotatable portion, a torque pivoting portion, a pulling portion, and a controller. The securing portion and the rotatable portion are provided for securing a user's shank and foot. This torque pivoting portion can create a torque causing the rotatable portion moving back. The pulling portion has a controller so as to pull the rotatable portion to rotate between a first angle and a second angle so that it can reduce possibility of the plantar fasciitis and ease pain of the plantar fasciitis. Hence, this invention can achieve an active rehabilitation exercise. The belt's pulling interval time can be adjusted. It has a safety switch to ensure its product safety. It is convenient that the user can use a wireless device to operate this system. In addition, the user can be informed about current condition via an audio device. | 07-14-2011 |
| 20110142966 | AQUEOUS EXTRACTS OF ANOECTOCHILUS SPP. KINSENOSIDE AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR HEPATOPROTECTION - A pharmaceutical composition useful for hepatoprotection is provided. The composition comprises an effective amount of kinsenoside or a pharmaceutically acceptable salt or ester thereof. An aqueous extract of | 06-16-2011 |
| 20110123448 | OIL BODY CARRIERS, USES IN TARGET THERAPY AND/OR DETECTION OF THE SAME, AND FUSION PROTEINS COMPRISED THEREIN - An oil body carrier, its uses in target therapy and/or detection, and a fusion protein comprised therein are provided. The oil body carrier comprises: | 05-26-2011 |
| 20110082197 | Method for inhibiting formation and/or activation of osteoclasts using flemingia macrophylla extract or lespedeza flavanone A - A method for inhibiting the formation and/or activation of osteoclasts in a mammal comprising administrating an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or ester thereof to the mammal is provided: | 04-07-2011 |
| 20110082103 | Anoectochilus SPP. polysaccharide extracts for stimulating growth of advantageous bacteria, stimuating release of granulocyte colony-Stimulating factor, modulating T helper cell type I, and/or modulating T helper cell type II and uses of the same | 04-07-2011 |
| 20110081625 | Denture - A denture is adapted to communicate with a radio frequency identification (RFID) reader. The denture includes a denture main body and at least one RFID tag embedded in the denture main body for storage of identification information of a user of the denture. The RFID tag transmits the information to the RFID reader by radio frequency wave. | 04-07-2011 |
| 20100168064 | NOVEL HYDROPHILIC DERIVATIVES OF 2-ARYL-4-QUINOLONES AS ANTICANCER AGENTS - 2-aryl-4-quinolones are converted into phosphates by reacting with tetrabenzyl pyrophosphate to form dibenzyl phosphates thereof, which are then subject to hydrogenation to replace dibenzyl groups with H, followed by reacting with Amberlite IR-120 (Na+ form) to form disodium salts. The results of preliminary screening revealed that these phosphates showed significant anti-cancer activity. A novel intermediate, 2-selenophene 4-quinolone and Λ/, Λ/-dialkylaminoalkyl derivatives of 2-phenyl-4-quinolones are also synthesized. These novel intermediates exhibited significant anticancer activities. | 07-01-2010 |
| 20080241283 | Aqueous extracts of anoectochilus spp. kinsenoside-comprising pharmaceutical compositions useful for hepatoprotection and uses of the same - A pharmaceutical composition useful for hepatoprotection is provided. The composition comprises an effective amount of kinsenoside or a pharmaceutically acceptable salt or ester thereof. An aqueous extract of | 10-02-2008 |
