| CHILDRENS HOSPITAL LOS ANGELES Patent applications |
| Patent application number | Title | Published |
|---|
| 20120078267 | INTRATHORACIC PACEMAKER - The present invention provides a fully intrathoracic artificial pacemaker. The pacemaker is of sufficiently compact size to allow for implantation of both the electrode and the power source within the chest cavity. In exemplary embodiments, a screw-type electrode is used for connection to heart tissue, and a relatively short lead is used to connect the electrode to a battery unit, which can comprise electronics for control of the pacemaker. An assembly for implanting the pacemaker, as well as methods of implanting the pacemaker, are disclosed. In embodiments, the device is designed as a fetal pacemaker. | 03-29-2012 |
| 20120039858 | METHODS AND COMPOSITIONS FOR INHIBITING PROPAGATION OF VIRUSES USING RECOMBINANT TETHERIN CONSTRUCTS - The present invention provides chimeric protein constructs having anti-viral activity, compositions and methods of using them, and nucleic acids encoding them. The chimeric proteins include an extracellular domain of a Tetherin protein fused to the transmembrane domain, and optionally cytoplasmic tail, of a different protein. The chimeric proteins have normal anti-viral tethering activity but are resistant to inhibition by anti-Tetherins. Ex vivo methods of gene therapy are also provided. | 02-16-2012 |
| 20110256110 | AMNIOTIC FLUID CELLS AND USES THEREOF - The present invention relates generally to amniotic fluid derived renal progenitor cells positive for CD24 and OB-cadherin and subpopulations thereof, as well as methods of isolating and uses thereof. The invention is further directed to preventing and treating kidney damage with a population of amniotic fluid derived c-kit positive stem cells. | 10-20-2011 |
| 20110212858 | SYNTHETIC POLY D/L LYSINE FOR CONTROL OF DIRECTION AND RATE OF NEURITE GROWTH AND REGENERATION - The present invention provides for use of poly-D/L-lysine (PLL) to control the growth of neural cells in vitro and in vivo. The invention describes the activity of defined PLL lines on neural cells and the ability to use the compound to control the direction and rate of growth of neurites on solid substrates. High-throughput screening assays are provided as are medical devices and therapies for treatment of neuronal injury or malfunction. | 09-01-2011 |
