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CHILDREN HOSPITAL MEDICAL CENTER

Cincinnati, OH US

CHILDREN HOSPITAL MEDICAL CENTER Patent applications
Patent application numberTitlePublished
20100069653METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES - A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained.03-18-2010