| Centre National De La Recherche Scient Patent applications |
| Patent application number | Title | Published |
|---|
| 20120083494 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS - The present invention provides novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and/or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular alcohol disorder, drug abuse, growth retardation, cachexia, short-, medium-, and/or long term regulation of energy balance, short-, medium-, and/or long term regulation (stimulation and/or inhibition) of food intake, intake of rewarding food, adipogenesis, adiposity and/or obesity, body weight gain and/or reduction, diabetes, diabetes type I, diabetes type II, tumor cell proliferation, inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and/or gastrectomy (ghrelin replacement therapy). | 04-05-2012 |
| 20120058037 | BORON CARBIDE AND METHOD FOR MAKING SAME - The invention relates to boron carbide and to a method for making the same, as well as to a super-abrasive material and a machine device including said boron carbide. The boron carbide of the invention has the following formula BC5 and has a diamond-type cubic structure with a mesh parameter a=3.635±0.006 Å. The boron carbide of the invention can particularly be used in the field of machining. | 03-08-2012 |
| 20110128674 | SOLVENTS AND NOVEL ELECTROLYTIC COMPOSITIONS HAVING A LARGE RANGE OF STABILITY AND HIGH CONDUCTIVITY - The present invention is concerned with novel polar solvents and novel electrolytic compositions comprising such solvents, and having a high range of stability, as required for applications in the field of electrochemistry. The present solvents have a highly polar amide function, and preferably combine with a salt soluble in the solvent and having an anion with a delocalized charge, and at least one polymer, to form an electrolytic composition. | 06-02-2011 |
| 20100320088 | MICRODEVICE FOR TREATING LIQUID SPECIMENS - A device for forming at least one circulating flow, or vortex, at the surface of a drop of liquid, including at least two first electrodes forming a plane and having edges facing each other, such that the contact line of a drop, deposited on the device and fixed relatively to the device, has a tangent forming, when projected onto the plane of the electrodes, an angle between 0° and 90° with the edges facing each other of the electrodes. | 12-23-2010 |
| 20100266576 | USE OF A CAMELID SINGLE-DOMAIN ANTIBODY FOR DETECTING AN OLIGOMERIC FORM OF AN AMYLOID BETA PEPTIDE AND ITS APPLICATIONS - Use of camelid single-domain antibodies for detecting an oligomeric form of the amyloid β peptide 42 and their therapeutic and diagnostic applications. | 10-21-2010 |
| 20100255038 | PURIFIED POLYPEPTIDE COMPRISING OR CONSISTING OF A C-TERMINUS MSP1 ANTIGEN FROM PLASMODIUM FALCIPARUM CARRYING A GLYCOSYL-PHOSPHATIDYL-INOSITOL GROUP (GPI) - The present invention relates to a purified polypeptide comprising or consisting of a C-terminus MSP1 antigen from | 10-07-2010 |
| 20100240040 | METHOD FOR SCREENING FOR SELECTIVE MODULATOR OF THE NF-KB PATHWAY ACTIVATION - The invention relates to methods for screening for selective modulator of NF-κB pathway activation. The invention concerns methods for primary screening molecules that potentially modulate (activate or inhibit) the NF-κB pathway activation by identifying and selecting molecules modulate the interaction of NEMO with other proteins. The invention also concerns methods for secondary screening for modulator (activator or inhibitor) of the NF-κB pathway activation. | 09-23-2010 |
| 20100216990 | NOVEL PHOTOCHROMIC MATERIALS - The invention relates to hybrid organic-inorganic materials containing molybdenum and having photochromic properties. The invention also relates to the use thereof, particularly in cosmetics and in the glass industry, e.g. in glazing applications or in the production of ocular glasses. | 08-26-2010 |
| 20100112455 | SOLVENTS AND NOVEL ELECTROLYTIC COMPOSITIONS HAVING A LARGE RANGE OF STABILITY AND HIGH CONDUCTIVITY - The present invention is concerned with novel polar solvents and novel electrolytic compositions comprising such solvents, and having a high range of stability, as required for applications in the field of electrochemistry. The present solvents have a highly polar amide function, and preferably combine with a salt soluble in the solvent and having an anion with a delocalized charge, and at least one polymer, to form an electrolytic composition. | 05-06-2010 |
| 20100041072 | PROCESS FOR IDENTIFYING A LIGAND THAT BINDS TO THE NEP BINDING SITE FOR THE SMR1 PENTAPEPTIDE - The invention relates to the therapeutic use of a SMR1-peptide or a pharmaceutically active amount of said SMR1-peptide, for the preparation of a therapeutic composition for preventing or treating diseases wherein a modulation of the activity of a membrane metallopeptidase, notably a membrane-zinc metallopeptidase, is sought, in a mammal, specifically in a human. | 02-18-2010 |
| 20090206299 | SOLVENTS AND NOVEL ELECTROLYTIC COMPOSITIONS HAVING A LARGE RANGE OF STABILITY AND HIGH CONDUCTIVITY - The present invention is concerned with novel polar solvents and novel electrolytic compositions comprising such solvents, and having a high range of stability, as required for applications in the field of electrochemistry. The present solvents have a highly polar amide function, and preferably combine with a salt soluble in the solvent and having an anion with a delocalized charge, and at least one polymer, to form an electrolytic composition. | 08-20-2009 |
| 20090156503 | CELL PENETRATING PEPTIDES FOR INTRACELLULAR DELIVERY OF MOLECULES - The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX | 06-18-2009 |
| 20090131320 | PEPTIDES MODULATING THE ACTIVITY OF THE ENGRAILED TRANSCRIPTION FACTOR - The invention relates to peptides which can become fixed to the engrailed transcription factor and which can modulate the activity thereof. | 05-21-2009 |
| 20090120997 | SATURABLE ABSORBER COMPONENT AND METHOD FOR MANUFACTURING A SATURABLE ABSORBER COMPONENT - The invention relates to a saturable absorber component comprising an absorbent material located between a front mirror and a rear mirror as well as a method for manufacturing a saturable absorber component. | 05-14-2009 |
| 20090110700 | ACELLULAR IMMUNOGENIC COMPOSITIONS AND ACELLULAR VACCINE COMPOSITIONS AGAINST BACILLUS ANTHRACIS - The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against | 04-30-2009 |
| 20090017454 | BIOSENSORS, METHOD FOR OBTAINING THE SAME AND USES THEREOF - The invention relates to biosensors, methods for obtaining them and their use for detecting, assaying or locating, in direct immunofluorescence, a ligand such as an antigen or hapten, in a heterogeneous population. The biosensor includes (i) at least one fragment of a receptor which is protein in nature, capable of binding to a ligand via an active site, where at least one amino acid residues of the fragment located in the proximity of the active site is naturally present in the form of a cystein (Cys) residue, or is substituted with a Cys residue, and (ii) a fluorophore coupled to the Cys residue. | 01-15-2009 |
