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CellCentric Limited

CellCentric Limited Patent applications
Patent application numberTitlePublished
20110138491Compositions and Method for Epigenetic Modification of Nucleic Acid Sequences in Vivo - Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilising a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy.06-09-2011