CAROLUS THERPEUTICS, INC. Patent applications |
Patent application number | Title | Published |
20110262386 | METHODS OF TREATING INFLAMMATION - Disclosed herein, in certain embodiments, is a method for treating an MIF-mediated disorder. In some embodiments, the method comprises administering an active agent that inhibits (i) MIF binding to CXCR2 and CXCR4 and/or (ii) MIF-activation of CXCR2 and CXCR4; (iii) the ability of MIF to form a homomultimer; or a combination thereof. | 10-27-2011 |
20110070184 | METHODS AND COMPOSITIONS FOR TREATING ATHEROSCLEROSIS AND RELATED CONDIDTIONS - Described herein are methods for treating or preventing a atherosclerosis by inhibiting the activation or binding of macrophage migration inhibitory factor to CXCR2 and CXCR4. Such inhibition is achieved by administration of either a single agent or a combination of agents. Also described herein are agents that inhibit MIF-binding or MIF-activation of CXCR2 or CXCR4. Further described are pharmaceutical compositions comprising such agents and their use for treating or preventing atherosclerosis. | 03-24-2011 |
20110044988 | METHODS OF TREATMENT USING ANTI-MIF ANTIBODIES - Disclosed herein, in certain embodiments, is a method for treating an inflammatory disorder. In some embodiments, the method comprises administering an active agent that inhibits (i) MIF binding to CXCR2 and CXCR4 and/or (ii) MIF-activation of CXCR2 and CXCR4; (iii) the ability of MIF to form a homomultimer; or a combination thereof. | 02-24-2011 |