| CARL ZEISS MICROIMAGING GMBH Patent applications |
| Patent application number | Title | Published |
|---|
| 20120002274 | MICROSCOPE COMPRISING MULTIPLE OPTICAL SYSTEMS IN THE IMAGING BEAM PATH - A microscope comprising multiple optical systems in the imaging beam path and at least one subassembly, the optical effect of which in relation to the imaging beam path can be modified by controlling the subassembly, e.g. a group of lenses or a diaphragm that can be moved in the direction of the optical axis, a diaphragm having a variable aperture, a digital zoom device, a shutter, or a focusing device. The microscope includes a control unit which is designed to generate control signals for the subassembly in a first mode of operation to regulate or control the functional parameters exclusively of the imaging optical system with which the subassembly is associated, and additionally in a second mode of operation to regulate or control the functional parameters of the entire optical system of the microscope. | 01-05-2012 |
| 20110284767 | COMBINATION MICROSCOPY - A method for generating an image of a sample by a microscopy method including varying local resolution, wherein at least two of the following microscopy methods are combined: laser scanning microscopy, a microscopy method wherein the sample is excited to luminescence by structured line or wide area illumination, and a first microscopy image is generated from the images thus obtained, having increased local resolution greater than the optical resolution of the image, a further microscopy method according to the PAL principle, by which a second microscopy image is generated, indicating geometric locations of marker molecules emitting luminescent radiation at an increased local resolution relative to the optical resolution, and a further microscopy method, wherein the sample is marked using marking molecules suitable for the STED, ESA, or RESOLFT technique, and a third microscopy image is generated of STED, ESA, or RESOLFT, wherein the obtained images are superimposed. | 11-24-2011 |
| 20110255075 | Spectrometric assembly and method for determining a temperature value for a detector of a spectrometer - The invention relates to a spectrometric assembly and method for determining a temperature value for a detector of a spectrometer. It is conventional to record the detector temperature in an optoelectronic detector using a thermal temperature sensor in order to compensate for temperature fluctuations. Due to the finite distance between the detector and the temperature sensor, the accuracy of the temperature detection is limited. According to the invention, the detector temperature should be recordable at high accuracy and with little effort. In addition to means for spectral division of incident tight and an optical detector for spectrally resolved detection of a spectral range of the divided light, a second optical detector is provided for detection of a partial range of this spectral range as a reference detector, wherein sensitivity of the reference detector is substantially temperature-independent. The ratio of the signals of both detectors is a highly accurate measurement for the relative temperature of the first detector due to the temperature independence of the sensitivity of the reference detector, and can be determined with little effort. | 10-20-2011 |
| 20110226965 | INCREASED RESOLUTION MICROSCOPY - Method for spatially high-resolution luminescence microscopy in which label molecules in a sample are activated to emit luminescence radiation comprising activating only a subset of the label molecules in the sample, wherein activated label molecules have a distance to the closest activated molecules that is greater or equal to a length which results from a predetermined optical resolution, detecting the luminescence radiation, generating a frame from the luminescence radiation, identifying the geometric locations of the label molecules with a spatial resolution increased above the predetermined optical resolution, repeating the steps and forming a combined image, and controlling the acquisition of the several frames by evaluating at least one of the frames or a group of the frames and modifying at least one variable for subsequent repetitions of the steps of generating frames for combining into an image. | 09-22-2011 |
| 20110187846 | SYSTEM FOR REMOTE VIEWING AND DISPLAY OF A SLIDE - A method for creating a virtual slide is provided. A virtual slide is a digital representation of an area of interest of a microscope slide. One method is to use a motorized microscope that can move a specimen with respect to a microscope objective. With such a system, one can capture one or more images through a microscope objective, such that a region of interest is imaged. Each image is then joined together to form a composite or “virtual image.” In one embodiment, after a virtual slide is created, a user may fully utilize the full capabilities of the remote microscope. Among these capabilities is a set of “optical objectives” and “virtual objectives.” Optical objectives are images created by digitizing an image through a microscope objective in real time. Virtual objectives are digitally created magnifications created by utilizing the existing virtual slide data to digitally create a field of view. | 08-04-2011 |
| 20110149388 | OPERATING CIRCUIT AND CONTROL METHOD FOR A PHOTOMULTIPLIER - A operating circuit and control method for protecting a PMT having a photocathode, a plurality of dynodes and an anode against overloading with a shorter reaction time, and to allow it to be switched on again rapidly. For this purpose, a switch is provided for electrically short circuiting the photocathode with the first dynode, or a switch is provided for reversing the polarity of the voltage between the photocathode and the first dynode. | 06-23-2011 |
| 20110122491 | ILLUMINATION ARRANGEMENT FOR TIRF MICROSCOPY - A TIRF illumination having a high axial resolution at low complexity. A TIRF illumination device is designed as a module and comprises an optical fiber and a collimating optic, wherein the collimating optic is mounted in front of a light discharge opening of the optical fiber, such that it collimates light exiting divergently from the optical fiber into a parallel light bundle, such that the excitation light can be applied to a sample outside of the detection beam path. The numerical aperture of the excitation is thus decoupled from the numerical aperture of detection, such that a standard microscope objective is sufficient for detection. | 05-26-2011 |
| 20110119034 | METHOD FOR RECORDING PULSE SIGNALS - A method for recording pulse signals which allows the reconstruction of a time reference. The time of every pulse signal event can be determined by counting sampling result bits preceding the respective sampling result bit using the known sampling frequency. For this purpose, every period of the sampling frequency is associated with a bit representing the respective sampling result and the sampling result bits are stored one by one and per channel in data blocks. The sampling frequency is preferably higher than a pixel clock, a sampling result bit associated with a flank of the pixel clock being marked. The pixel clock can thus be synchronized with the individual events exactly per sampling period. The invention further relates to the field of fluorescence correlation spectroscopy using confocal microscopes or laser scanning microscopes. | 05-19-2011 |
| 20110082590 | CONTROLLER FOR ACTUATORS IN MICROSCOPE LENSES - A controller for microscope lenses for correcting spherical aberration and for adjusting particularly difficult to access microscope lenses to an optimum of imaging quality, enabling automatic adjustment of the different actuators of a microscope lens, to effect a simple, cost-effective, user-friendly, and precise balance, particularly of cover slip deviations and different base thicknesses of Petri dishes for the purposes of increasing imaging quality. At least two movable elements of a microscope objective supporting lenses or lens groups, are provided in a movable manner in the axial direction along the optical axis of the microscope objective relative to the housing of the microscope lens in a motor-actuated manner by way of respective adjusting rings. A controller externally controlled and disposed in the microscope lens is provided for storing different characteristic curves for paths of motion of the movable elements. | 04-07-2011 |
| 20110069380 | VARIABLE MICROSCOPE SYSTEM - A variable microscope system, which, beginning at the object plane, includes a main lens system, a zoom lens system consisting of several lens groups, and a relay system connected in series to the zoom lens system. In the microscope system, according to the invention, at least one main lens system for infinite mapping of an object is provided and the zoom lens system is designed in such a way that the infinite beam path from the lens system is mapped in an intermediate image, wherein an aperture collimation is provided in a subsequently positioned relay system. An advantage of the microscope system, according to the invention, versus prior art lies in an improved eye pupil adjustment to the illumination as well as to the observation of samples with the contrast method. | 03-24-2011 |
| 20110062348 | DEVICE AND METHOD FOR THE EVANESCENT ILLUMINATION OF A SAMPLE - A device for the evanescent illumination of a sample, including an optical illumination element with an optical corrective element and an objective arranged downstream from the corrective element, to evanescently illuminate the sample with a supplied ray beam containing optical radiation with at least two different wavelengths. The corrective optical element has a transverse chromatic aberration which, during the illumination, leads to the optical radiation penetrating the pupil of the objective at different heights relative to the optical axis varying according to the wavelength. The corrective optical element is selected in such a way that the wavelength-related difference of the penetration depths of the radiation into the sample is reduced during the evanescent illumination. | 03-17-2011 |
| 20110051232 | MICROSCOPE WITH RETAIN FOCUS CONTROL - A microscope including an imaging optical unit, a sample stage for supporting a sample to be examined, a movement unit, by which the distance between sample stage and imaging optical unit can be altered, a focus measuring unit, which measures the present focus position and outputs a focus measurement signal, a control unit for maintaining a predetermined focus position for examinations of the sample that are separated from one another in time. The control unit receives the focus measurement signal and derives a deviation of the present focus position from the predetermined focus position. Dependent on the deviation derived the movement unit, changes the distance between sample stage and imaging optical unit so that the predetermined focus position is maintained. The control unit drives the movement unit ( | 03-03-2011 |
| 20110043905 | MICROSCOPE HAVING FOCUS-HOLDING UNIT - The invention relates to a microscope having a stage for supporting a sample to be examined, a recording sensor, an imaging optic for imaging the sample onto the recording sensor, a moving unit by means of which the distance between the stage and the imaging optic can be changed, a control unit for controlling an image recording of the sample and a focus-holding unit for maintaining a prescribed focal position for image recording of the sample at temporal intervals, wherein the focus-holding device comprises at least one hardware element and one software module, wherein the focus-holding unit is fully integrated in the control unit, on both the hardware and software sides. | 02-24-2011 |
| 20110042555 | DETECTOR ARRANGEMENT HAVING INCREASED SENSITIVITY - To increase the sensitivity of detector arrangements, it is known that light deflection elements in the form of a line arrays having spherical elements may be used to focus incident light onto light-sensitive regions of the detector. Manufacturing such line arrays is complex and cost intensive, especially in small lot numbers. The increased sensitivity of the detector array can be achieved easily and inexpensively by using a novel light deflection element. The detector arrangement therefore has a light deflection element having light entrance surfaces, deflecting incident light by refraction onto light-sensitive regions of the detector. Light entrance surfaces of the light deflection element are inclined with respect to one another and are designed as planar surfaces. The detector arrangement is suitable in particular for detection of light emanating from a specimen in a microscope, preferably in a laser-scanning microscope. | 02-24-2011 |
| 20110038041 | OPERATING DEVICE FOR THE FOCUSING OPERATION OF A MICROSCOPE - The focusing operation of a microscope, control rotary knobs which receive the motion of fingers or hand of an operator to change the focus position relative to a sample under observation. Two of the control rotary knobs are on a common shaft and coaxial with one another and rotationally fixed with respect to one another, and are connected to a position encoder. A toggle switch which is connected to the control circuit and can be actuated by touching or moving one or both rotary control knobs. Whereby the drive circuit is configured such that it generates, as a function of the rotation of the two rotary knobs and as a function of the actuation or position of the toggle switch, a rough or fine adjustment of the focus position relative to the sample under observation. | 02-17-2011 |
| 20110007319 | Arrangement for Determining the Reflectivity of a Sample - The invention relates to an arrangement for measuring the reflectivity of the direct or scattered reflection of a sample ( | 01-13-2011 |
| 20110007311 | METHOD AND ARRANGEMENT FOR THE TIME-RESOLVED SPECTROSCOPY USING A PHOTON MIXING DETECTOR - The present invention relates to a solution for time-resolved spectroscopy, wherein the sample to be analyzed is illuminated by a modulated light source, and the spectrum reflected therefrom is recorded in a time-resolved manner and evaluated. In the method according to the invention for time-resolved spectroscopy, a sample to be analyzed is irradiated by a modulated light source having short light pulses, and the radiation emitted by the sample is represented via imaging optical elements and a spectral-selective element on a sensor disposed in the image plane, and the signals thereof are evaluated by a control and regulating unit, and/or stored. The sensor disposed in the image plane is a PMD sensor, which in addition to the intensity values also determines the running times of the radiation emitted by the sample, and forwards the same to the control and regulating unit. Although PMD sensors were originally intended for object recognition, particularly in traffic, the use thereof in many other technical fields is conceivable and advantageous. The solution provided herein describes the use of PMD sensors in spectroscopy, particularly for the time-resolved analysis of samples. However, the use of PMD sensors is also possible in Raman spectrometry, or for the measurement of luminescence, such as for differentiating phosphorescence and fluorescence light. | 01-13-2011 |
| 20100321752 | METHOD FOR CORRECTING A CONTROL OF AN OPTICAL SCANNER AND THE OPTICAL SCANNER - In a method for correcting a control of an optical scanner ( | 12-23-2010 |
| 20100321686 | DEVICE FOR OPTICAL SPECTROSCOPY AND MECHANICAL SWITCH FOR SUCH A DEVICE - The disclosure provides a device for optical spectrometry, wherein the reference beam and the measuring beam between the deflector and the detector input, in particular between the deflector output and the detector or between a device connecting the optical paths and the detector exhibit the same (the identical) etendue and the same (the identical) optical axis. | 12-23-2010 |
| 20100315706 | TUBE UNIT FOR MICROSCOPES - A tube unit for microscopes which has a tube lens, including two components with an intermediate, large air separation and an overall positive refractive power. The air separation is at least half the size of the focal length f of the tube lens. A roof edge mirror or another suitable deflection element is arranged between the two components of the tube lens. The roof edge mirror includes two mirrors which can be tilted with respect to one another, and which is able to be tilted around its roof edge. The tilting movement or the tilting angle of the tiltable mirror or deflection element corresponds to half the tilt or half the tilting angle of the tube or eyepiece viewing system. | 12-16-2010 |
| 20100309573 | Optics Changer - The invention relates to an optics changer for arranging an optical element in a target position in a changer chamber g of an optical device accessible from the outside via a insertion channel, comprising a base frame and the optical element that is pivotally fastened to the base frame via a swivel mechanism, wherein the swivel mechanism effects a pivoting movement of the optical element when the optics changer is inserted through the insertion channel in the changer chamber starting at o a predetermined insertion depth such that after inserting, the optical element is placed and pivoted in the target position. | 12-09-2010 |
| 20100253942 | METHOD AND DEVICE FOR CHARACTERIZING SILICON LAYER ON TRANSLUCENT SUBSTRATE - A method for the characterization of a silicon layer on a translucent substrate, in particular, for the characterization of a solar cell blank, includes detecting by at least one optical detector, the light transmitted through the silicon layer and/or reflected on the silicon layer. The method also includes determining a degree of absorption of the silicon layer for at least one wavelength by means of the detected light. The method further includes determining a quantity ratio between an amorphous fraction and a crystalline fraction of the silicon layer or between one of these fractions and the total of these fractions by means of the degree of absorption. | 10-07-2010 |
| 20100108188 | Arrangement for Filling a Container with Bulk Material - The invention relates to an arrangement for filling a container ( | 05-06-2010 |
| 20100063681 | METHOD AND ARRANGEMENT FOR THE STEERING OF A VEHICLE - The invention relates to a method by which image data from the terrain lying in front of a vehicle ( | 03-11-2010 |
| 20100033811 | AUTOFOCUS DEVICE FOR MICROSCOPY - A microscope including an objective which images a sample along a microscope beam path, and an autofocus device, which is coupled into the microscope beam path via a beam splitter at a location behind the objective direction, a A light modulator for generating a two-dimensional, intensity-modulated modulation object, is located in the autofocus beam path in a plane conjugated to the focal plane of the objective or intersects the latter and is imaged into the focal plane of the objective. A camera records a two-dimensional image onto which the modulation object's image is imaged. The image plane of the camera intersects a plane that is conjugated to the modulation object or is located in the plane and the camera detecting the contrast of the modulation object's image located in the sample. | 02-11-2010 |
| 20100014159 | STAGE DRIVE FOR MICROSCOPES - A stage drive for moving a microscope stage designed as a mechanical stage including a first drive element linked to a first output element, and a second drive element, which is linked to a second output element. Through first and second transmission means, the first output element is linked to a first stage element and the second output element is linked to a second stage element of the mechanical stage supported by the first stage element. The stage elements are supported so as to be displaceable relative to a fixed base element in orthogonal directions X, Y in a plane extending normal to the optical axis of the microscope beam path. The at least one stage drive includes at least one drive element and at least one output element and is arranged in the base element so as to be displaceable in X direction and/or Y direction within an adjustment range and lockable. | 01-21-2010 |
| 20090284841 | MICROSCOPE OBJCTIVE - The invention relates to a microscope objective with preferably anti-symmetric lenses or lens groups with an optical magnification of −100 and a visual field factor of 20. | 11-19-2009 |
| 20090168060 | Spectrometric Measurement System and Method for Compensating for Veiling Glare - The present solution is directed to a measuring system and a method for determining spectrometric measurement results with high accuracy. The spectrometric measuring system, comprises a radiation source, an entrance slit, a dispersion element, and a detector with detector elements arranged in a linear or matrix-shaped manner in one or more planes. The detector has an even distribution of at least two different wavelength-selective filters on its detector elements. While detectors from photography and video applications are used for this purpose, use of the invention is not limited to the visible spectral region. Further, color filters on the pixels may be omitted or modified in the manufacturing process. It is also possible to use other types of detectors in which the wavelength-selective filters and associated detectors are arranged one behind each other in a plurality of planes in which complete color information is available to each individual picture point. | 07-02-2009 |
| 20090129032 | MODULAR SYSTEM CONTROLLED ACCORDING TO POWER REQUIREMENTS - The invention relates to a modular system comprising a primary module, several individual modules that can be connected to said primary module and a power supply unit that is connected to the primary module and supplies the connected individual modules with a voltage. According to the invention, the system is equipped with a descriptor element for each individual module. The descriptor element is read by the primary module and encodes or displays the power requirements of the assigned individual module. The primary module reads the descriptor elements of the connected individual modules and uses said elements to determine the total power requirements of the modular system, or of all connected individual modules. | 05-21-2009 |
| 20090109447 | Microscope and Microscope Microexamination Procedure Method for the Measurement of the Surface Profile of an Object - The invention provides a microscope for measuring the surface profile of an object, including (1) an illumination module which directs illumination radiation with different wavelengths to different surface portions of the object in such a way that a predetermined object intersection length range is illuminated for every portion, and (2) a detection module which detects sample radiation of every portion successively in time. Wherein the detection module directs the sample radiation into a detection beam path via a scanner and confocally images another wavelength of the sample radiation in a plane for every intersection length to be detected. The detection module also detects the intensity of the confocally imaged sample radiation in a wavelength-dependent manner and derives therefrom the position of the corresponding surface portion of the object. Wherein the detection module has a color module arranged between the scanner and the plane, through which the sample radiation passes. | 04-30-2009 |
| 20090103089 | SPECTROMETER WITH A SLIT FOR INCIDENT LIGHT AND FABRICATION OF THE SLIT - A spectrometer including an entrance slit and the production of the entrance slit. The spectrometer includes a housing, an entrance slit, and an imaging diffraction grating inside the housing for splitting and imaging the light onto an optoelectric detector. The detector is arranged inside the housing. The housing and the base plate are connected to each other by mutually cooperating positioning members. The entrance slit, the positioning members of the base plate and the holding members for receiving and mounting the detecting device are integral parts of the base plate and are produced from the base plate in a precise manner, in a suitable form and in defined mutual positions by, for example, laser cutting or liquid jet cutting. The positioning members of the base plate and/or the holding members for the detecting device can be provided as resilient elements. | 04-23-2009 |
| 20090052020 | Stereoscopic microscope with high numerical aperture - The invention is directed to a telescope-type stereomicroscope which is outfitted with an objective and two magnification changers which are arranged downstream of the objective. The invention provides a telescope-type stereomicroscope in which the light coming from an object that is being examined enters the objective, two light bundles of the light re-exiting from the objective which are oriented parallel to one another enter the magnification changers, the optical axes of the magnification changers are arranged at a fixed distance B from one another, each magnification changer has an entrance pupil for the light bundle associated with it, which entrance pupil has a diameter D | 02-26-2009 |
| 20080310017 | MICROSCOPE FOR OBSERVING A SAMPLE IN THE BRIGHT FIELD ILLUMINATION BY TRANSMITTED LIGHT OR IN FLUORESCENCE-CONTRAST EPI-ILLUMINATION - A microscope for observing an object selectably using the bright-field transmitted light contrast procedure or the incident-light fluorescence contrast procedure. During the bright-field transmitted light contrast procedure, an illumination beam path is directed from a bright-field light source to the object and an imaging beam path is directed from the object through the microscope objective into the microscope tube, which includes a fluorescence unit that includes a fluorescence excitation light source, an illumination optical system, a filter set having at least one excitation filter and at least one emission filter, as well as a beamsplitter. The fluorescence unit is mounted movably, so that in a first end position of movement the beamsplitter and the emission filter are out of the imaging beam path of the microscope and in a second end position of movement they are in the imaging beam path between the microscope objective and the microscope tube. | 12-18-2008 |
| 20080247050 | MICROSCOPE OBJECTIVE - The invention relates to a microscope objective which consists of at least four lenses or groups of lenses and can preferably be used to improve image contrast. | 10-09-2008 |
