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Caritas St. Elizabeth Medical Center of Boston, Inc.

Caritas St. Elizabeth Medical Center of Boston, Inc. Patent applications
Patent application numberTitlePublished
20120014879USE OF TUMOR NECROSIS FACTOR-alpha RECEPTOR p75 FOR TREATMENT OF ISCHEMIA-INDUCED NEOVASCULARIZATION - Improvements on the basic method used for BEAMing increase sensitivity and increase the signal-to-noise ratio. The improvements have permitted the determination of intrinsic error rates of various DNA polymerases and have permitted the detection of rare and subtle mutations in DNA isolated from plasma of cancer patients.01-19-2012
20100162419TUMOR-INITIATING CELLS AND METHODS OF USE - Provided herein are an isolated or enriched population of tumor initiating cells derived from normal cells, cells susceptible to neoplasia, or neoplastic cells. Methods of use of the cells for screening for anti-hyperproliferative agents, and use of the cells for animal models of hyperproliferative disorders including metastatic cancer, diagnostic methods, and therapeutic methods are provided.06-24-2010
20100047776Cell-based screening assays for compounds that regulate the expresion of a tumor marker dj-1 - The present invention generally provides compositions and methods that are useful for the treatment or prevention of a neoplasm, and screening methods that can be used to detect compounds that modulate the activity of a DJ-I gene.02-25-2010
20100028312Stably transformed bone marrow-derived cells and uses thereof - The invention provides compositions comprising genetically modified bone marrow cells and related therapeutic and diagnostic methods. Transduced bone marrow cells can be therapeutically administered to a subject, such as a human patient to provide for the expression of an encoded protein in the subject in need thereof.02-04-2010
20090105148COMPOSITIONS AND METHODS FOR TREATING MYOCARDIAL INFARCTION - The invention features compositions and methods that are useful for preventing or treating a cardiac disease or for promoting cardiac health following a myocardial infarction. The invention further features compositions and methods for promoting angiogenesis, cell proliferation, and/or decreasing apoptosis in muscle tissue, such as cardiac tissue. The invention provides for the expression of human growth hormone in cardiac muscle following a myocardial infarction.04-23-2009
20090023794Use of Sumoylation Inhibitors for the Treatment of Neurodegenerative Disease - The invention generally provides screening methods for the identification of therapeutic compounds useful for the treatment of a neurodegenerative disease, and related prophylactic and therapeutic compositions and methods.01-22-2009

Patent applications by Caritas St. Elizabeth Medical Center of Boston, Inc.