| CARA THERAPEUTICS, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120015930 | SUBSTITUTED IMIDAZOHETEROCYCLE DERIVATIVES - The present invention provides substituted imidazoheterocycles having the general structure of formula I: | 01-19-2012 |
| 20110275609 | BICYCLIC PYRAZOLO-HETEROCYCLES - The present invention provides substituted pyrazolo-heterocycles having the general structure of formula I | 11-10-2011 |
| 20110257105 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF - The invention relates to synthetic peptide amide ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 10-20-2011 |
| 20110212882 | USES OF KAPPA OPIOID SYNTHETIC PEPTIDE AMIDES - The invention relates to methods of use of synthetic peptide amides that are ligands of the kappa opioid receptor in the treatment and prevention of kappa opioid receptor-associated diseases and conditions; and particularly to uses of these agonists in the prophylaxis, inhibition and treatment of pain, inflammation and pruritis associated with a variety of diseases, disorders and conditions. Inflammatory conditions preventable or treatable by the methods of the invention include diseases and conditions associated with elevated levels of a proinflammatory cytokines, such as TNF-α, IL-β, IL-6, MMP-1 and MMP-3. Such diseases and conditions include cardiovascular inflammation, neurological inflammation, skeletal inflammation, muscular inflammation, gastrointestinal inflammation, ocular inflammation, otic inflammation, inflammation due to insect bites and inflammation due to wound healing; atherosclerosis, ischemia, restenosis and vasculitis; of asthma, Sjogren's syndrome, pulmonary inflammation, chronic airway inflammation and chronic obstructive pulmonary disease (COPD), allergy, psoriasis, psoriatic arthritis, eczema, scleroderma, atopic dermatitis and systemic lupus erythematosus, arthritis, synovitis, osteomyelitis, rheumatoid arthritis, osteoarthritis and ankylosing spondylitis; septicemia and septic shock, diabetes, glucose intolerance, insulin resistance and obesity, colitis, ulcerative colitis, Crohn's disease, IBD and IBS, and the inflammatory diseases and conditions due to tumor proliferation, tumor metastasis or transplantation rejection. | 09-01-2011 |
| 20110190336 | AZABENZIMIDAZOLONES - Compounds are provided having the general structure of formula I: | 08-04-2011 |
| 20110144121 | BICYCLIC PYRAZOLO-HETEROCYCLES - The present invention provides substituted pyrazolo-heterocycles having the general structure of formula I | 06-16-2011 |
| 20110118186 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF - The invention relates to synthetic peptide amides that are ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 05-19-2011 |
| 20110034443 | USES OF SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides methods of prevention and treatment of cannabinoid receptor-associated diseases and conditions, wherein the method includes administering a substituted imidazoheterocyclic compounds having the structure of formula I or a pharmaceutically acceptable salt, acid salt, hydrate, solvate or stereoisomer of a compound having the structure of formula I. | 02-10-2011 |
| 20100105777 | AMIDE OR THIOAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PAIN - The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders related thereto as well as a method for treatment of pain and disorders related thereto, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification. | 04-29-2010 |
| 20100075910 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF - The invention relates to synthetic peptide amides that are ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 03-25-2010 |
| 20090312271 | Method For Elevating Prolactin in Mammals - Methods for elevating and stabilizing prolactin levels in a mammal including methods of treating disorders and conditions associated with reduced serum levels of prolactin are provided. Also provided are methods of using certain synthetic tetrapeptide amides which are peripherally selective kappa opioid receptor agonists to elevate or stabilize serum prolactin levels. | 12-17-2009 |
| 20090264373 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF - The invention relates to synthetic peptide amide ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 10-22-2009 |
| 20090247502 | SUBSTITUTED PYRIDOXAZINES - The invention provides compounds having the structure of formula I, | 10-01-2009 |
| 20090156508 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF - The invention relates to synthetic peptide amides that are ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 06-18-2009 |
| 20090149450 | SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides substituted imidazoheterocyclic compounds having the structure of formula I | 06-11-2009 |
| 20090075973 | BENZO-FUSED HETEROCYCLES - The present invention provides benzo-fused heterocyclic compounds having the structure of formula I, as well as prodrugs, stereoisomers, racemates, salts, hydrates, solvates, acid salt hydrates and isomorphic crystalline forms thereof. | 03-19-2009 |
| 20090075907 | SYNTHETIC PEPTIDE AMIDES - The invention relates to synthetic peptide amide ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P | 03-19-2009 |
| 20080318935 | SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides substituted imidazoheterocyclic compounds having the structure of formula I | 12-25-2008 |
| 20080214537 | BRIDGED PHENANTHRIDINES - Bridged phenanthridine compounds having the structure of formula I or of formula II are provided: | 09-04-2008 |
