| Cambridge Enterprise Limited Patent applications |
| Patent application number | Title | Published |
|---|
| 20120115742 | METHODS FOR IDENTIFICATION - The invention relates to methods for the discovery of new chemical entities and pharmaceutical compositions with broad-spectrum chemokine inhibitor (BSCI) activity, together with the use of such agents as anti-inflammatory medicaments. In one aspect, there is provided a method for the identification of a compound or agent with BSCI activity comprising the steps of (a) firstly one or more candidate compounds or agents are screened for binding to a somatostatin receptor such as the type 2 somatostatin receptor (sstr2); then (b) compounds or agents which show binding to the somatostatin receptor are tested for BSCI activity in a functional assay. | 05-10-2012 |
| 20120112178 | OPTOELECTRONIC DEVICES - An optoelectronic device comprises electon donor D and acceptor A semiconducting species and an intervening co-oligomeric or copolymeric species provided to alter the energy transfer characteristics of excitons to or from the interface between the said electron acceptor and donor species. The intervening species may be of the form A | 05-10-2012 |
| 20120087905 | TREATMENT OF DISEASES RELATED TO HYPERACTIVITY OF THE COMPLEMENT SYSTEM - Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the C3b-feedback cycle and the generation and pro-inflammatory effects of iC3b. Methods, agents, and compositions for treatment of such diseases are described. | 04-12-2012 |
| 20120065401 | METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE - Isolated and purified chemokine peptides, variants, and derivatives thereof, as well as chemokine peptide analogs, are provided. | 03-15-2012 |
| 20120046198 | Ligand Libraries for Screening GPCRs - The invention provides compounds of general formulae (I)-(IV) or pharmaceutically acceptable salts thereof: | 02-23-2012 |
| 20120038842 | Phase Modulation Devices for Optical Applications - An optical phase modulation device having a layer of flexoelectro-optic effect liquid crystal material and electrode for applying an electric field to the layer of liquid crystal material. In this way, the optic axis of the liquid crystal layer can be deflected. This provides a phase shift to light transiting the liquid crystal layer. The substrate of the device is based on a liquid crystal over silicon (LCOS) microdisplay. The device is capable of providing multilevel phase shifts, e.g. for holographic displays. | 02-16-2012 |
| 20120037516 | HYDROGEN SENSING APPARATUS AND METHOD - An apparatus and methods are provided for the accurate determination of hydrogen content in fluid media at elevated temperatures. The apparatus consists of a proton conducting solid electrolyte in contact with an internal metal/hydrogen reference standard, in which the electrolyte and the reference material are in a chemically stable contact. The electrical signal generated is a function of the hydrogen concentration on the measuring side. | 02-16-2012 |
| 20120032994 | WIDE TEMPERATURE-RANGE SMECTIC LIQUID CRYSTAL MATERIALS - A method of making a wide temperature-range smectic liquid crystal material comprises taking a wide temperature-range nematic mixture and doping this with a mesogenic silicon-containing material. Aspects of the invention provide wide temperature-range smectic materials and devices using the smectic materials. | 02-09-2012 |
| 20120028903 | MODULATION OF THE ACTIVITY AND DIFFERENTIATION OF CELLS EXPRESSING THE OSTEOCLAST-ASSOCIATED RECEPTOR - This invention relates to the finding that collagen peptides bind to the osteoclast-associated receptor (OSCAR) and stimulate the activation and/or differentiation of OSCAR expressing cells, such as osteoclasts and osteoclast precursor cells. Collagen peptides are described which may be useful in the modulation of the differentiation and/or activation of OSCAR expressing cells, for example in the treatment of bone defects and disorders characterized by altered differentiation and/or activation of OS-CAR expressing cells. | 02-02-2012 |
| 20120027811 | Formulations of Viable Cells for Oral Delivery - This invention relates to solid formulations for the oral delivery of live microbial cells which comprise dried viable cells and small amounts of a bile acid binding agent, for example, an anion exchange resin such as cholestyramine. The presence of bile acid binding agents in the formulation significantly increases the survival of the cells in the intestinal tract and facilitates delivery of the viable cells to the intestine. | 02-02-2012 |
| 20120010600 | METHOD OF OVERNIGHT CLOSED-LOOP INSULIN DELIVERY WITH MODEL PREDICTIVE CONTROL AND GLUCOSE MEASUREMENT ERROR MODEL - A closed-loop method for insulin infusion overnight uses a model predictive control algorithm (“MPC”). Used with the MPC is a glucose measurement error model which was derived from actual glucose sensor error data. That sensor error data included both a sensor artifacts component, including dropouts, and a persistent error component, including calibration error, all of which was obtained experimentally from living subjects. The MPC algorithm advised on insulin infusion every fifteen minutes. Sensor glucose input to the MPC was obtained by combining model-calculated, noise-free interstitial glucose with experimentally-derived transient and persistent sensor artifacts associated with the FreeStyle Navigator® Continuous Glucose Monitor System (“FSN”). The incidence of severe and significant hypoglycemia reduced 2300- and 200-fold, respectively, during simulated overnight closed-loop control with the MPC algorithm using the glucose measurement error model suggesting that the continuous glucose monitoring technologies facilitate safe closed-loop insulin delivery. | 01-12-2012 |
| 20120003228 | METHODS FOR PREDICTING AUTOIMMUNE DISEASE RISK - The invention relates to means and methods for determining whether a subject is at high or low risk of autoimmune disease progression by determining the CD8 or CD4 cell subtype of the subject. Autoimmune diseases of particular interest include vasculitis, systemic lupus erythematosus (SLE), rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. The invention also relates to means and methods for determining the CD8 or CD4 cell subtype of a subject, e.g. for predicting responses to infection, vaccination and/or transplantation. | 01-05-2012 |
| 20110319268 | SUPERCONDUCTOR FABRICATION - A seed crystal for the fabrication of a superconductor is grown from a rare-earth oxide having the basic formula X | 12-29-2011 |
| 20110280573 | OPTICAL BEAM STEERING - This invention generally relates to an optical beam steering apparatus and a method of manufacturing an optical beam steering apparatus, and more particularly to an optical add drop multiplexer (OADM) such as a reconfigurable OADM (ROADM) comprising the optical beam steering apparatus. In one embodiment, the apparatus comprises a slab and a plurality of optical elements in or on a first surface of said slab, the plurality of optical elements including at least one liquid crystal on silicon element, the apparatus being arranged such that at least one optical beam can propagate freely in the slab from one of said plurality of optical elements to another one of said plurality of optical elements via a reflection from a second surface of the optical beam steering apparatus. | 11-17-2011 |
| 20110273657 | OPTICAL BEAM STEERING - The invention relates to optical beam steering. There is described an optical beam steering apparatus, comprising: a splitter arranged to split an optical beam into at least a first part having a first polarisation and a second part having a second polarisation, said first and second polarisations being substantially mutually orthogonal; a first liquid crystal device region arranged to receive said first part and to have director orientation substantially aligned to said first polarisation; and a second liquid crystal device region arranged to receive said second part and to have director orientation substantially aligned to said second polarisation. | 11-10-2011 |
| 20110202238 | ACTIVE STEERING CONTROLLER - A system for controlling a vehicle. The vehicle has a steerable front axle and at least one further steerable axle and the system comprises means for determining the path of a reference lead point at the front of the vehicle. There is also means for determining the path of a follow point at the rear of the vehicle, and means for driving the at least one further steerable axle of the vehicle such that the deviation between the path of the lead point of the vehicle and the follow point is within a predetermined range whilst the vehicle is in motion. | 08-18-2011 |
| 20110185449 | Modified Xylan Production - Methods and means for producing xylan structures in plants having a non-native saccharide moiety substitution side chain component, plants and plant cells comprising modified xylan structures, methods of identifying mutant plants comprising xylan structures in plants having a non-native saccharide moiety substitution pattern side chain component, uses thereof, and isolated xylan structures and uses thereof. | 07-28-2011 |
| 20110165554 | METHODS AND BIOMARKERS FOR DIAGNOSING AND MONITORING PSYCHOTIC DISORDERS - A method of diagnosing or monitoring a psychotic disorder, or predisposition thereto, comprises measuring, in a sample taken from a subject, the levels of one or more peptide biomarkers listed herein. | 07-07-2011 |
| 20110163280 | Optical Nanomaterial Compositions - The present invention provides compositions (“Optical Nanomaterial Compositions”) comprising one or more nanomaterials and an optical coupling gel or an optical adhesive. The invention also provides methods for using the Optical Nanomaterial Compositions as an index-matching gel, an optical adhesive or an optical film, all of which are suitable for optical and sensing devices applications, including but not limited to noise suppression, passive Q-switching, mode-locking, waveform shaping, optical switching, optical signal regeneration, phase conjugation, in filter devices, dispersion compensation, wavelength conversion, soliton stabilization, microcavity applications, in interferometers (such as the Gires-Tournois interferometer), optical, magneto-optical or electro-optical modulation, biochemical sensors and photodetectors. | 07-07-2011 |
| 20110150873 | ANTI-INFLAMMATORY COMPOSITIONS AND COMBINATIONS - The invention relates to the use of Broad-Spectrum Chemokine Inhibitors (BSCIs), and in particular members of the acylaminolactam class of pharmaceutical agents, for the prevention, prophylaxis, treatment or amelioration of symptoms of inflammatory diseases. In particular, improved compositions consisting of BSCI agents combined with one or more additional active pharmaceutical agents in order to achieve improved anti-inflammatory efficacy with a reduced side-effect profile are described and claimed. | 06-23-2011 |
| 20110140091 | Electro-optic Diode Devices - A light emissive or photovoltaic device comprising: a cathode structure for injecting electrons, the cathode structure having one or more constituent regions; an anode structure for injecting holes, the anode structure having one or more constituent regions; and an organic light emissive component located between the anode structure and the cathode structure; the refractive indices and the thicknesses of the or each constituent region of the cathode and anode structures and of the light emissive component being such that the emission or absorption spectrum of the device is substantially angularly dependent. | 06-16-2011 |
| 20110136670 | HIGH TEMPERATURE SUPERCONDUCTORS - Compositions are disclosed of a matrix of a high temperature superconductive oxide such as YBCO, with non-superconductive particles distributed in the matrix. The non-superconductive particles comprise at least one rare earth element (RE) and at least one of tantalum (Ta) and niobium (Nb). Of particular interest are non-superconductive particles of composition RE-Ta | 06-09-2011 |
| 20110038798 | AGENTS FOR DETECTING AND IMAGING CELL DEATH - This invention relates to molecular imaging agents comprising an S78C mutant synaptotagmin I C2A domain. These agents may be useful in detecting or assessing cell death in vitro and in vivo, for example in tumours following cancer treatment. | 02-17-2011 |
| 20110035155 | PROTEIN AGGREGATION PREDICTION SYSTEMS - We describe methods for identifying aggregation-prone regions in structured—that is folded—proteins. Embodiments of the method use a local propensity for aggregation (A | 02-10-2011 |
| 20110021943 | NEURAL INTERFACE - This invention relates to the neural interface comprising one or more electrode-coupled microchannels. Each electrode-coupled microchannel comprises a microchannel for accommodating regenerating nerve axons; and one or more electrodes exposed to the interior of said microchannel. The one or more electrodes may comprise (i) a stimulation array suitable for generating an extracellular stimulus current which induces an action potential in an axon in the microchannel; and/or (ii) a recording array which detects an extracellular signal in the microchannel indicative of an action potential in an axon in the microchannel. Interfaces as described may be useful in blocking pain, treating misrouted motor nerves; repair or treating nerve injury; or controlling or providing sensation and/or proprioception from a prosthesis. | 01-27-2011 |
| 20110020574 | EXTRUDED MATERIALS HAVING CAPILLARY CHANNELS - The present invention’ provides extrusion-processable materials having a plurality of capillary channels therethrough, and apparatus and methods for manufacturing such materials. The capillaries may be occupied by gases, liquids or other phases. The materials may be anisotropic foams which have high voidage. The methods and apparatus include quench cooling ( | 01-27-2011 |
| 20110003792 | ANTI-INFLAMMATORY AGENTS - The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, | 01-06-2011 |
| 20110002912 | COMPOSITION - The present invention relates to a composition for improving stem cell integration. The present invention also relates to a method of improving stem cell integration and kits for improving stem cell integration. | 01-06-2011 |
| 20100330677 | Improved Reprogramming of Mammalian Cells, and Cells Obtained - Expression of reprogramming factors such as Sox2, klf4, c-myc, Nanog, LIN28 and Oct4 followed by culture in a MEK inhibitor and a GSK3 inhibitor reprograms tissue cells. The invention provides new uses of these inhibitors, for example in inducing completion of the transcriptional resetting of so-called pre-pluripotent (pre-iPS) stem cells, for example as obtained from mammalian neural stem cells or epiblast stem cells treated with single or combinations of the reprogramming factors, expressed transiently or by integrative vectors. Also provided are systems for reprogramming an epiplast stem cells independently of the use of there inhibitors. | 12-30-2010 |
| 20100327653 | AIR BRAKING SYSTEM - An air braking unit for use in an air braking system. The air braking unit is arranged to be positioned, in use, at a vehicle wheel, and comprises an inlet for receiving, in use, compressed air from a central source. At least one first valve is arranged to selectively allow compressed air from the inlet to enter a wheel brake chamber in use. At least one second valve is arranged to selectively allow air from the brake chamber to be released via an outlet to the atmosphere in use and control means controls the first and second valves to operate to selectively control the air pressure in the brake chamber in use. | 12-30-2010 |
| 20100324089 | Anti-inflammatory composition - The invention relates to 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one, and its pharmaceutical compositions and its use for preparing a medicament intended to prevent or treat inflammatory disorders. | 12-23-2010 |
| 20100291597 | SECRETOGRANIN AND VGF PEPTIDE BIOMARKERS AND USES THEREOF - Secretogranin II and VGF peptides are biomarkers for major depressive disorder. They are useful in methods of diagnosing, monitoring and screening. | 11-18-2010 |
| 20100280441 | OVERNIGHT CLOSED-LOOP INSULIN DELIVERY WITH MODEL PREDICTIVE CONTROL AND GLUCOSE MEASUREMENT ERROR MODEL - A closed-loop system for insulin infusion overnight uses a model predictive control algorithm (“MPC”). Used with the MPC is a glucose measurement error model which was derived from actual glucose sensor error data. That sensor error data included both a sensor artifacts component, including dropouts, and a persistent error component, including calibration error, all of which was obtained experimentally from living subjects. The MPC algorithm advised on insulin infusion every fifteen minutes. Sensor glucose input to the MPC was obtained by combining model-calculated, noise-free interstitial glucose with experimentally-derived transient and persistent sensor artifacts associated with the FreeStyle Navigator® Continuous Glucose Monitor System (“FSN”). The incidence of severe and significant hypoglycemia reduced 2300- and 200-fold, respectively, during simulated overnight closed-loop control with the MPC algorithm using the glucose measurement error model suggesting that the continuous glucose monitoring technologies facilitate safe closed-loop insulin delivery. | 11-04-2010 |
| 20100248368 | BIOMATERIAL - A process for the preparation of a composite biomaterial comprising: providing a first substantially solid component comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and optionally an inorganic material, said component having at least a surface portion that is porous; providing a fluid composition comprising one or more of collagen, a glycosaminoglycan, albumin, hyaluronan, chitosan, and synthetic polypeptides comprising a portion of the polypeptide sequence of collagen, and a liquid carrier, and optionally an inorganic material; contacting said fluid composition with said porous surface portion of said first component; cooling said fluid composition to a temperature at which the liquid carrier transforms into a plurality of solid crystals or particles; removing at least some of the plurality of solid crystals or particles by sublimation and/or evaporation. | 09-30-2010 |
| 20100247477 | SUPRAMOLECULAR HANDCUFFS IN POLYMERIC ARCHITECTURE - This invention pertains generally to supramolecular polymers comprising a polymeric molecule linked to a first CB[8] guest molecule and an attachment compound linked to a second CB[8] guest molecule, wherein the first and second CB[8] guest molecules form a ternary host-guest complex with a CB[8] molecule which non-covalently links the polymeric molecule and the attachment compound in a supramolecular polymer. These polymers are useful as vehicles for delivery of a therapeutic compound for use in a method of treatment of the human or animal body, in particular for use in a method of delivering the therapeutic compound to a target site in an individual. The invention also provides methods for the preparation of the supramolecular polymers. | 09-30-2010 |
| 20100242592 | SHEAR STRESS SENSORS - This invention relates to hot film shear stress sensors and their fabrication. We describe a hot film shear stress sensor comprising a silicon substrate supporting a membrane having a cavity underneath, said membrane bearing a film of metal and having electrical contacts for heating said film, and wherein said membrane comprises a silicon oxide membrane, where in said metal comprises aluminium or tungsten, and wherein said membrane has a protective layer of a silicon-based material over said film of metal. In preferred embodiments the sensor is fabricated by a CMOS process and the metal comprises aluminium or tungsten. | 09-30-2010 |
| 20100203650 | BIOMOLECULE BINDING LIGANDS - The invention provides biomolecule binding ligands, collections of biomolecule binding ligands, and their use in the purification of biological mixtures and in the identification of ligands having an affinity for a substance. The ligand is a compound of formula (III) or a compound of formula (IV): wherein for compounds of formula (I) one of R | 08-12-2010 |
| 20100190201 | Methods - The invention relates to a method of detecting an altered behaviour in a population of cells, said method comprising determining at least one of the following characteristics of the population of cells; (i) the proportion of stem cells, proliferating cells and differentiated cells in said cell population; or (ii) the size of stem cell clusters in said cell population; or (iii) the separation of stem cell clusters in said cell population; and comparing said at least one characteristic to a reference value, wherein a difference between the determined value and the reference value indicates an altered behaviour in said population of cells. Preferably the cells are mammalian, more preferably human epithelial cells, more preferably human epidermal cells. | 07-29-2010 |
| 20100136542 | NUCLEIC ACID AMPLIFICATION AND TESTING - Methods for amplifying a target nucleic acid by self-sustained amplification methods are described. The methods are designed, in particular, to be carried out without use of specialised lab facilities or instruments. Compositions, lyophilised formulations, and kits for carrying out the methods are also described. | 06-03-2010 |
| 20100134629 | Strain Image Display Systems - A method of displaying strain image data for an imaged object, the method comprising: capturing strain image data defining deformation of said object over an imaged region of said object; processing said strain image data to determine local image quality data, said local image quality data comprising a measure of the quality of said strain image data varying over said imaged region; and displaying a representation of said strain image data for said imaged region of said object, using said local image quality data to provide a visual indication of the quality of said displayed representation varying over said imaged region or to improve a quality of said displayed representation of said strain image data. | 06-03-2010 |
| 20100128877 | Systems and Methods for Providing Opportunistic Security for Physical Communication Channels - Systems and methods of providing opportunistic security for physical communication channels are disclosed. One disclosed method is for opportunistic secure communication on a main channel between a sender device and a receiver device when an eavesdropper device is listening on an eavesdropper channel. This example method includes transmitting, in a first time period in which signal quality on the main channel is better than signal quality on the eavesdropper channel, symbols that are randomly selected from a set of symbols. The method also includes transmitting, in a second time period in which signal quality on the main channel is not better than signal quality on the eavesdropper channel, coding information associated with the randomly selected symbols. The method also includes reconciling the randomly selected symbols using the coding information. | 05-27-2010 |
| 20100113518 | METHODS OF USING ANTI-INFLAMMATORY COMPOUNDS - The invention relates to the use of 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one for preparing a medicament intended to prevent or treat inflammatory disorders. | 05-06-2010 |
| 20100060326 | CONTROL OF POWER SEMICONDUCTOR DEVICES - This invention relates to a control method and a circuit for MOS-gated power semiconductor switching devices such as IGBTs or MOSFETs, which allows control and optimisition of the current and voltage commutation of a power semiconductor switching device and freewheel diode pair in the basic half-bridge circuit found in a wide range of equipment. The method comprises the stages of: applying, upon receipt of a switch-on command signal, a voltage function to the control terminal or the gate of the power semiconductor switching device that allows a regulated current rise in the device whilst maintaining the voltage across the device falling at a predetermined rate; and at the instant when the voltage across the diode begins to change from the on-state towards the off-state level, applying a voltage function to the control terminal or the gate of the power semiconductor switching device to enable the voltage falling across the power semiconductor switching device to track the voltage falling across the diode in order to ensure a fast and controlled completion of the switching operation without diode reverse voltage overshoot. The gate drive automatically modifies the voltage function according to the working condition thereby accounting for the actual operating conditions. | 03-11-2010 |
| 20100046695 | APPARATUS AND METHOD FOR ACQUIRING SECTIONAL IMAGES - Disclosed is a computer implemented method of interrogating volumetric data, the method including the steps of: defining a reference surface relative to the volumetric data; providing an interrogation window lying in a movable interrogation plane intersecting the reference surface and the interrogation window intersecting the volumetric data, said interrogation plane having a pole lying in it about which pole said interrogation plane is rotatable, wherein movement of the interrogation plane provides a corresponding movement of the interrogation window; for each movement of the interrogation plane, determining the point of intersection of said pole and said reference surface, determining the relative angle of rotation of said interrogation plane about said pole and determining the angle of inclination of said pole to said reference surface; and on the basis of said determinations, providing a sectional image through the volumetric data corresponding to the position of the interrogation window within the volumetric data. Also disclosed is a computer system for implementing the method according to any one of the preceding claims, the system includes a processor for performing the steps of the method and a visual display for displaying said sectional image. | 02-25-2010 |
| 20100044684 | BLENDED POLYMER FETS - A method for forming a semiconductor body, the method comprising: forming a mixture of an organic semiconducting material and a binder material; causing the semiconducting material to at least partially solidify; and causing the binder material to crystallize in such a way as to cause the semiconducting material to at least partially segregate from the binder material. | 02-25-2010 |
| 20100043837 | METHOD OF CONTROLLING CONTAMINATION OF A SURFACE - A method is described of controlling contamination of a surface exposed to a carbonaceous material and ionising radiation, such as EUV radiation, DUV radiation or electrons. The method comprises cyclically supplying to the surface a first gas comprising an oxidising species, for example NO, for reacting with carbonaceous deposits formed on the surface from the carbonaceous material, followed by a second gas comprising a reducing species, for example CO, for reacting with oxidising species on the surface. | 02-25-2010 |
| 20100040938 | LEAD RECYCLING - The present invention describes a method of recycling lead from lead containing waste, the method comprising the steps of mixing the battery paste with aqueous citric acid solution so as to generate lead citrate; isolating lead citrate from the aqueous solution; and converting the lead citrate to lead and/or lead oxide. | 02-18-2010 |
| 20100003528 | Nanomaterial Polymer Compositions and Uses Thereof - The present invention is directed to compositions (“Nanomaterial Polymer Compositions”) comprising a silicone polymer and a nanomaterial, including but not limited to, a single or multi-walled nanotube, a nanowire, a nanodot, a quantum dot, a nanorod, a nanocrystal, a nanotetrapod, a nanotripod, a nanobipod, a nanoparticle, a nanosaw, a nanospring, a nanoribbon, a branched nanomaterial, or any combination thereof. The Nanomaterial Polymer Compositions are useful for optical and sensing devices including but not limited to noise suppression, passive Q-switching, mode-locking, waveform shaping, optical switching, optical signal regeneration, phase conjugation or filter devices, dispersion compensation, wavelength conversion, a soliton stabilization, microcavity applications, interferometers; optical, magneto-optical or electro-optical modulation; and biochemical sensors and photodetectors. The Nanomaterial Polymer Compositions are also useful in soft lithography processes. | 01-07-2010 |
| 20100002324 | Optical Nanomaterial Compositions - The present invention provides compositions (“Optical Nanomaterial Compositions”) comprising one or more nano-materials and an optical coupling gel or an optical adhesive. The invention also provides methods for using the Optical Nanomaterial Compositions as an index-matching gel, an optical adhesive or an optical film, all of which are suitable for optical and sensing de-vices applications, including but not limited to noise suppression, passive Q-switching, mode-locking, waveform shaping, optical switching, optical signal regeneration, phase conjugation, in filter devices, dispersion compensation, wavelength conversion, soliton stabilization, microcavity applications, in interferometers (such as the Gires-Tournois interferometer), optical, magneto-optical or electro-optical modulation, biochemical sensors and photodetectors. | 01-07-2010 |
| 20090317413 | DETECTION OF HUMAN PLATELET ANTIGEN (HPA) ANTIBODIES - This invention relates to recombinant GPIIIa molecules that lack the ligand binding βA domain and bind to HPA-1 antibodies in monomeric form. These GPIIIa molecules can be recombinantly expressed at high levels and may be useful, for example, in the detection of HPA-1 antibodies. Such detection may be useful, for example, in the diagnosis and therapy of HPA antibody disorders such as Neonatal Alloimmune Immune Thrombocytpenia (NAIT), Post Transfusion Purpura (PTP) and Platelet Refractoriness (PR). | 12-24-2009 |
| 20090203535 | ACOUSTIC WAVE TRANSDUCER SUBSTRATE AND MEASUREMENTS USING THE SAME - An acoustic wave transducer substrate is provided, the substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites. The growth-promotion sites are preferably for promoting fibril formation. The invention also provides a method of screening a candidate compound for an effect on fibril growth, including the steps of: providing an acoustic wave transducer substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites; causing oscillation of the substrate; contacting the substrate surface with a sample fluid comprising polypeptide molecules and a candidate compound; and measuring one or more parameters of the substrate oscillation to monitor the accumulation of said polypeptide molecules of interest in the presence and absence of said candidate compound. Alteration of the accumulation of said polypeptide molecules of interest in the presence of said candidate compound as compared with that in the absence of said candidate compound indicates that the candidate compound has an effect of fibril growth. | 08-13-2009 |
| 20090186196 | Multistable Structural Member and Method for Forming a Multistable Structural Member - Disclosed is a multistable structural member ( | 07-23-2009 |
| 20090158749 | Magnetocaloric Refrigerant - The invention provides the use of a material of general formula (I): | 06-25-2009 |
| 20090128875 | Phase retrieval and phase hologram synthesis - A method of retrieving phase information from input intensity information, representative of a target image, in which a Fourier transform is performed on data and the result used in forming a phase estimate, the phase estimate being inverse Fourier transformed, thereby producing magnitude and phase replay, and wherein not only is the phase reply component but also data derived from the magnitude replay component, iteratively fed back. | 05-21-2009 |
| 20090128872 | Method of forming an image and image projection device - A method of forming an image comprising providing a device for imparting respective phase shifts to different regions of an incident wavefront, wherein the phase shifts give rise to an image in a replay field, and causing zero-order light to be focused into a region between the replay field and the device. | 05-21-2009 |
| 20090116128 | Viewing device - A viewing device comprises: a pair of optically aligned lenses which are moveable relative to each other to vary the gap between facing surfaces of the lenses, and a linkage for controlling the relative motion. The linkage includes first and second elongate members which crossover each other at a crossover pivot connection. The first elongate member extends between a slidably moveable pivot connection which is arranged to transmit relative motion to the first lens of the pair and a pivot connection which is arranged to transmit relative motion to the second lens of the pair. The second elongate member extends between a slidably moveable pivot connection which is arranged to transmit relative motion to the second lens and a pivot connection which is arranged to transmit relative motion to the first lens. The connections are arranged such that the linkage can open and close in a concertina- or scissor-like fashion. | 05-07-2009 |
| 20090022771 | BIOMATERIAL - A process for the preparation of a composite biomaterial comprising an inorganic material and an organic material, the process comprising: (a) providing a first slurry composition comprising a liquid carrier, an inorganic material and an organic material; (b) providing a mould for the slurry; (c) depositing the slurry in the mould; (d) cooling the slurry deposited in the mould to a temperature at which the liquid carrier transforms into a plurality of solid crystals or particles; (e) removing at least some of the plurality of solid crystals or particles by sublimation and/or evaporation to leave a porous composite material comprising an inorganic material and an organic material; and (f) removing the material from the mould. | 01-22-2009 |
| 20090008261 | Oxygen Generation Apparatus and Method - An oxygen generator for an oxygen-generation apparatus has a proton-conducting membrane ( | 01-08-2009 |
| 20080274901 | COMPOSITE ELECTRICAL CONDUCTORS AND METHOD FOR THEIR MANUFACTURE - An elongate composite electrical conductor with at least one superconducting core region including processed core material surrounded by sheath material such as Cu. The processed core material has a peripheral portion of ex situ reacted MgB | 11-06-2008 |
