| BUCK INSTITUTE FOR AGE RESEARCH Patent applications |
| Patent application number | Title | Published |
| 20120071468 | METHODS OF TREATING MILD COGNITIVE IMPAIRMENT (MCI) AND RELATED DISORDERS - The invention provides compositions and methods for the treatment of mild cognitive impairment (MCI), and for inhibiting, reducing, delaying and/or preventing the progression of MCI to Alzheimer's disease. The methods entail administering an effective amount of one or more compounds selected from the group consisting of tropisetron, disulfuram, honokiol and nimetazepam. The methods also are useful for prophylactic and therapeutic treatment of amyloidogenic diseases, including Alzheimer's disease. | 03-22-2012 |
| 20110135689 | Vaccine, therapeutic composition and methods for treating or inhibiting francisella tularenis - The present invention is directed to compounds and methods for treating a mammal exposed to | 06-09-2011 |
| 20100099609 | eAPP AND DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE - This invention provides methods of reducing levels of amyloid beta (Aβ) protein and/or netrin-1 in a mammal. In certain embodiments the methods involve administering to the mammal a fragment of an amyloid precursor protein, or a mutant amyloid precursor protein, in an amount sufficient to decrease circulating levels of free Aβ protein in said mammal, wherein said fragment is a fragment of the extracellular domain of APP or a mutant thereof that binds amyloid beta protein and/or netrin-1. | 04-22-2010 |