| BROWN UNIVERSITY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120114214 | METHODS AND APPARATUS FOR IDENTIFYING SUBJECT MATTER IN VIEW DATA - In one aspect, a method and apparatus for detecting subject matter of interest in view data obtained by scanning an object including generating a filter adapted to respond to the subject matter of interest, splatting the filter onto a portion of the view data to provide a filter splat, and performing at least one operation on the portion of the view data using the filter splat to facilitate determining whether the subject matter of interest is present in the portion of the view data. | 05-10-2012 |
| 20120108655 | Methods of Diagnosing and Treating Carcinomas - Methods of diagnosing a carcinoma include comparing the expression of miRNAs in a sample with a control and determining ratios of expression of miRNAs. Methods of treatment include administering a nucleic acid encoding a miR-375 gene product. Methods of optimizing treatment in a subject include determining expression of an miR21-gene product. | 05-03-2012 |
| 20110204219 | SYSTEM AND METHODS FOR DETERMINING MOLECULES USING MASS SPECTROMETRY AND RELATED TECHNIQUES - The present invention generally relates to mass spectrometry and related techniques, and in some cases, to determining single species using mass spectrometry. In certain instances, polymers such as DNA or RNA can also be sequenced. Certain embodiments of the invention relate to passing a polymer, such as DNA, RNA, a protein, a polypeptide, a polysaccharide, etc., through a pore and cleaving the polymer in sequence. For instance, the polymer may be cleaved using a laser or an electric field. In some embodiments, a property of at least one subunit of a polymer is determined using mass spectrometry. In some embodiments, a single ion (which may be a subunit of a polymer, or an ion based on another species) can be isolated in a mass spectrometer and a signal generated from the single ion. | 08-25-2011 |
| 20110125263 | METHOD FOR PRODUCING NANOSTRUCTURES ON A SURFACE OF A MEDICAL IMPLANT - A method for treating a surface of a medical implant to create nanostructures on the surface that results in increased in-vivo chondrocyte adhesion to the surface. Further, disclosed is a method to fabricate a drug delivery system. The drug delivery system includes a medical implant that has undergone a surface treatment process that results in the modification of the surface configuration and topography. The modified surface acts as a depot or reservoir for loaded biological material, biologic agents or pharmaceutical products. Additionally, a device for delivering pharmaceutical products or other biological materials is disclosed. The device includes integrally attached nanostructures that retain or adsorb the loaded pharmaceutical products and/or biological materials. Further disclosed is a medical implant that includes a surface configured to allow for and regulate protein adsorption. The surface of the medical implant has a layer of nanostructures rigidly attached with varying porosity and orientation that allow for surface protein adsorption to be controlled. | 05-26-2011 |
| 20110059904 | SERUM-BASED, DIAGNOSTIC, BIOLOGICAL ASSAY TO PREDICT PREGNANCY DISORDERS - The invention provides serum-based, diagnostic, biological assays for predicting disorders of pregnancy resulting from poor trophoblast and/or placental ischemia, including preeclampsia. Serum samples from such subjects exhibit an ability to disrupt the architecture involving fetal trophoblasts and maternal endothelial cells in a three-dimensional, dual cell co-culture system provided herein, in contrast to normal pregnancy serum samples. Based on these distinctions, the assays are employed to predict pregnancy outcomes as early as first trimester. | 03-10-2011 |
| 20110053766 | NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR - The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano-particles. In a preferred embodiment, the nano-particles are unstabilized nano-Se. Next, the sorbent material is exposed to mercury in an environment. As a result, the sorbent material captures and stabilizes mercury from the environment. In the preferred embodiment, the environment is an indoor space in which a fluorescent has broken. | 03-03-2011 |
| 20110052463 | NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR - The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano-particles. In a preferred embodiment, the nano-particles are unstabilized nano-Se. Next, the sorbent material is exposed to mercury in an environment. As a result, the sorbent material captures and stabilizes mercury from the environment. In the preferred embodiment, the environment is an indoor space in which a fluorescent has broken. | 03-03-2011 |
| 20110049045 | NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR - The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano-particles. In a preferred embodiment, the nano-particles are unstabilized nano-Se. Next, the sorbent material is exposed to mercury in an environment. As a result, the sorbent material captures and stabilizes mercury from the environment. In the preferred embodiment, the environment is an indoor space in which a fluorescent has broken. | 03-03-2011 |
| 20110048982 | NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR - The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano-particles. In a preferred embodiment, the nano-particles are unstabilized nano-Se. Next, the sorbent material is exposed to mercury in an environment. As a result, the sorbent material captures and stabilizes mercury from the environment. In the preferred embodiment, the environment is an indoor space in which a fluorescent has broken. | 03-03-2011 |
| 20110028333 | DIAGNOSING, PROGNOSING, AND EARLY DETECTION OF CANCERS BY DNA METHYLATION PROFILING - A method of employing DNA methylation analysis for the diagnosis, prognosis, and prediction of cancer. | 02-03-2011 |
| 20100323262 | REACTANT DELIVERY TO A REACTIVE SURFACE IN A CHANNEL - The present invention provides geometric arrangements for channels through which liquids or other fluids can be made to flow, for enhanced performance of fuel cells or other chemical or biochemical reactors or analyzers. Systems and methods including these improved geometries are described herein for enhanced performance of a variety of devices. Specifically, in one set of embodiments, the reactors comprise one or more microchannels comprising a tapered cross-sectional area and at least one reactive surface portion. By flowing a liquid comprising one or more reactants through the channel such that the cross-sectional area decreases in a downstream direction, relatively more reactant may be supplied to the wall at downstream positions relative to the amount that would be supplied in a system without a tapered cross-section. In some embodiments, the microchannel may be constructed and arranged such that the amount of reactant supplied to the wall conforms to a predetermined distribution. | 12-23-2010 |
| 20100228745 | SYSTEM, METHOD, AND APPARATUS FOR SORTING AT LEAST PARTIALLY DYNAMIC DATA - Embodiments of methods, apparatuses, devices and systems associated with sorting candidate values are disclosed. | 09-09-2010 |
| 20100110935 | Efficient Content Authentication In Peer-To-Peer Networks - A method and distributed network are provided. The method includes: providing an abstract tree structure having a root node, a plurality of tree nodes, and a plurality of leaf nodes, wherein each leaf node corresponds to at least a portion of data (box | 05-06-2010 |
| 20100050276 | Transgenic non-human animal models of apoptosis-mediated conditions - A transgenic non-human animal whose genome comprises a stable integration of a transgene that encodes at least one Fas-ligand protein operably-linked to a tetracycline-inducible promoter includes cells that express the transgene and undergo apoptosis. The transgenic non-human animal can be used to screen for compounds that inhibit apoptosis and to identify cells that are capable of differentiating in vivo. | 02-25-2010 |
| 20090191099 | HIGH-THROUGPUT SOLVENT EVAPORATOR AND GAS MANIFOLD WITH UNIFORM FLOW RATES AND INDEPENDENT FLOW CONTROLS - The evaporator ( | 07-30-2009 |
| 20090123053 | METHODS AND APPARATUS FOR MODEL-BASED DETECTION OF STRUCTURE IN VIEW DATA - In one aspect, a method and apparatus for determining a value for at least one parameter of a configuration of a model associated with structure of which view data has been obtained including detecting at least one feature in the view data, and determining the value for the at least one parameter of the configuration of the model based at least in part on the at least one feature. In another aspect, a method and apparatus for detecting at least one blood vessel from object view data obtained from a scan of the at least one blood vessel including generating a model of the at least one blood vessel, the model having a plurality of parameters describing a model configuration, determining a hypothesis for the model configuration based, at least in part, on at least one feature detected in the object view data, and updating the model configuration according to a comparison with the object view data to arrive at a final model configuration, so that the final model configuration represents the at least one blood vessel. | 05-14-2009 |
| 20090092875 | FUEL CELL, MEMBRANE ELECTRODE ASSEMBLY - An acid resistant composite catalyst comprising dumbbell-shaped composite nanoparticles each comprising a noble metal nanoparticle epitaxially conjugated to a ferrite particle, and/or flower-shaped composite nanoparticles each comprising a noble metal nanoparticle epitaxially conjugated to at least two ferrite particles. The acid resistant composite catalyst is useful to facilitate the reduction of oxygen. The acid resistant composite catalyst can be used in a fuel cell comprising a fuel electrode, an oxygen electrode, and a polymer electrolyte membrane placed between the fuel electrode and the oxygen electrode. The oxygen electrode includes the acid resistant composite catalyst. | 04-09-2009 |
| 20090022777 | Methods for progenitor cell recruitment and isolation - The invention relates to the use of one or more growth factors in a drug delivery system, optionally with an external mesh housing, to recruit and optionally harvest progenitor cells. These cells include those that normally reside in the bone marrow. | 01-22-2009 |
