Brookhaven Science Associates, LLC. Patent applications |
Patent application number | Title | Published |
20160139302 | Formation of Antireflective Surfaces - Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate. | 05-19-2016 |
20160135765 | ACTIVE WATER PHANTOM FOR THREE-DIMENSIONAL ION BEAM THERAPY QUALITY ASSURANCE - An Active Water Phantom is designed to provide fast, accurate, high resolution, complete Quality Assurance of patient-specific treatment plans utilizing intensity-modulated Ion Beam Therapy, prior to their delivery to the patient. The detection medium is a tissue-equivalent water-based liquid scintillator material. A three-dimensional pattern of scintillation light, emitted upon ion beam irradiation, is reconstructed from three orthogonal two-dimensional light yield profiles, which are read out for each individual beam energy layer. The 3-D information has dose measurement accuracy 1-2% and spatial resolution 1-2 millimeters. The measurement sequence provides up to four orders of magnitude more data characterizing the treatment plan than currently commercially available alternatives, all in a time period no greater than that needed for actual delivery of the dose fraction to a patient. The system provides sophisticated control and readout of the cameras or photo-detectors, data archiving and analysis, simulation capabilities, and 3-D dose image reconstruction and visualization. | 05-19-2016 |
20160002651 | Enhanced Triacylglycerol Accumulation in Vegetative Tissues of Plants - In the tgd1-1 mutant that displays substantially enhanced TAG synthesis and turnover, disruption of SUGAR-DEPENDENT1 (SDP1) TAG lipase or PEROXISOMAL TRANSPORTER1 (PXA1) severely decreases FA turnover, leading to an increase in leaf TAG content up to 9% of dry weight and total leaf lipid by three-fold. The membrane lipid content and composition of tgd1-1 sdp1-4 and tgd1-1 pxa1-2 double mutants are altered and they are compromised in growth and development and fertility. | 01-07-2016 |
20150376803 | Gas Diffusion Electrodes and Methods for Fabricating and Testing Same - Highly effective, standalone gas-diffusion electrodes (GDEs) and the methods for their manufacture and test are disclosed, Nanocataiysis are directly bonded on a gas diffusion layer, so that the integrity of the catalyst layer holds without polymer electrolyte membrane, facilitating minimization of electronic, prottmtc, and diffusion resistances in the catalyst layer. The devised embodiments provide examples showing a facile hanging-strip method for testing the standalone GDEs in a solution electrochemical cell, which removes the mA-cm | 12-31-2015 |
20150252484 | BIOMASS TRANSITION METAL HYDROGEN-EVOLUTION ELECTROCATALYSTS AND ELECTRODES - A catalytic composition from earth-abundant transition metal salts and biomass is disclosed. A calcined catalytic composition formed from soybean powder and ammonium molybdate is specifically exemplified herein. Methods for making the catalytic composition are disclosed as are electrodes for hydrogen evolution reactions comprising the catalytic composition. | 09-10-2015 |
20150217249 | C-11 Cyanide Production System - A method for providing | 08-06-2015 |
20150177376 | ATMOSPHERIC RADAR - Technologies are described effective to implement an atmospheric radar system. An antenna array transmits a wave toward an atmospheric target and receives a reflected wave that includes voltages corresponding to backscattered radar signal measurements. A processor includes a coherency matrix generator module effective to receive the voltages and generate a coherency matrix. The processor further includes an eigenvalue calculator module effective to receive the coherency matrix and calculate eigenvalues of the coherency matrix The processor includes an eigenvalue variable calculator module effective to receive the eigenvalues and calculate eigenvalue meteorological variables from the eigenvalues. The processor further includes an atmosphere display module effective to receive the eigenvalue meteorological variables and generate an output signal that corresponds to the meteorological property of the atmospheric target in response. | 06-25-2015 |
20150122324 | THIN-FILM PHOTOVOLTAIC DEVICE WITH OPTICAL FIELD CONFINEMENT AND METHOD FOR MAKING SAME - A photovoltaic device is provided that includes a first electrode layer and a second electrode layer; and a waveguiding structure disposed between the first electrode layer and the second electrode layer which includes an active layer adapted to convert photons transmitted to the active layer to electrons and holes. The waveguiding structure further includes a first layer adjacent the first electrode layer that includes a hole-conducting material having a first index of refraction, and a second layer including an electron-conducting material having a second index of refraction, wherein the active layer is disposed therebetween. The active layer has an index of refraction that is less than each of the first index of refraction and the second index of refraction and a thickness. The waveguiding structure is characterized by guided modes adapted for optically confining the photons within the active layer. | 05-07-2015 |
20150083585 | Molybdenum and Tungsten Nanostructures and Methods for Making and Using Same - The present invention provides molybdenum and tungsten nanostructures, for example, nanosheets and nanoparticles, and methods of making and using same, including using such nanostructures as catalysts for hydrogen evolution reactions. | 03-26-2015 |
20150045228 | Radio Frequency-Assisted Fast Superconducting Switch - A radio frequency-assisted fast superconducting switch is described. A superconductor is closely coupled to a radio frequency (RF) coil. To turn the switch “off,” i.e., to induce a transition to the normal, resistive state in the superconductor, a voltage burst is applied to the RF coil. This voltage burst is sufficient to induce a current in the coupled superconductor. The combination of the induced current with any other direct current flowing through the superconductor is sufficient to exceed the critical current of the superconductor at the operating temperature, inducing a transition to the normal, resistive state. A by-pass MOSFET may be configured in parallel with the superconductor to act as a current shunt, allowing the voltage across the superconductor to drop below a certain value, at which time the superconductor undergoes a transition to the superconducting state and the switch is reset. | 02-12-2015 |
20150017565 | Core-Shell Fuel Cell Electrodes - Embodiments of the disclosure relate to electrocatalysts. The electrocatalyst may include at least one gas-diffusion layer having a first side and a second side, and particle cores adhered to at least one of the first and second sides of the at least one gas-diffusion layer. The particle cores includes surfaces adhered to the at least one of the first and second sides of the at least one gas-diffusion layer and surfaces not in contact with the at least one gas-diffusion layer. Furthermore, a thin layer of catalytically atoms may be adhered to the surfaces of the particle cores not in contact with the at least one gas-diffusion layer. | 01-15-2015 |
20140370563 | COMPOSITIONS AND METHODS FOR THE RELIEF OF INHIBITION OF ALDEHYDE DECARBONYLASE - The present invention is related to compositions and methods for enhanced synthesis of hydrocarbons, particularly, but not limited to, alkanes. The invention, in one embodiment, utilizes the co-expression of a hydrogen peroxide metabolizing enzyme in the presence of an aldehyde decarbonylase enzyme to relieve hydrogen peroxide inhibition of the aldehyde decarbonylase enzyme by hydrogen peroxide. In a preferred embodiment a catalase-aldehyde decarbonylase expression construct and fusion peptide is used. The present invention also relates to microorganisms engineered to express said enzymes and to produce hydrocarbon molecules. | 12-18-2014 |
20140308520 | Methods for the Bio-programmable Crystallization of Multi-component Functional Nanoparticle Systems - The bio-programmable crystallization of multi-component functional nanoparticle systems is Ascribed, as well as methods for such bio-programmable crystallization, and the products resultant from such methods. Specifically, the systems disclosed and taught herein are directed to improved strategies for the DNA-mediated self-assembly of multi-component functionalized nanoparticles into three-dimensional order surperlattices, wherein the functionalization of the nanoparticles with DNA is independent of either the composition of the material, or the shape of the nanoparticles. | 10-16-2014 |
20140284568 | Azide Functionalized Poly(3-Hexylthiophene) and methods of Forming Same - This disclosure relates to a polymer having the formula: | 09-25-2014 |
20140231657 | RADIATION DETECTOR DEVICE FOR REJECTING AND EXCLUDING INCOMPLETE CHARGE COLLECTION EVENTS - A radiation detector device is provided that is capable of distinguishing between full charge collection (FCC) events and incomplete charge collection (ICC) events based upon a correlation value comparison algorithm that compares correlation values calculated for individually sensed radiation detection events with a calibrated FCC event correlation function. The calibrated FCC event correlation function serves as a reference curve utilized by a correlation value comparison algorithm to determine whether a sensed radiation detection event fits the profile of the FCC event correlation function within the noise tolerances of the radiation detector device. If the radiation detection event is determined to be an ICC event, then the spectrum for the ICC event is rejected and excluded from inclusion in the radiation detector device spectral analyses. The radiation detector device also can calculate a performance factor to determine the efficacy of distinguishing between FCC and ICC events. | 08-21-2014 |
20140217297 | Array of Virtual Frisch-Grid Detectors with Common Cathode and Reduced Length of Shielding Electrodes - A radiation detector system is disclosed that effectively solves the electron trapping problem by optimizing shielding of the individual virtual Frisch-grid detectors in an array configuration. | 08-07-2014 |
20140216539 | INTERDIGITATED ELECTRICAL CONTACTS FOR LOW ELECTRONIC MOBILITY SEMICONDUCTORS - Structures useful for forming contacts to materials having low charge carrier mobility are described. Methods for their formation and use are also described. These structures include interdigitated electrodes capable of making electrical contact to semiconducting materials having low electron and/or whole mobility. In particular, these structures are useful for organic semiconducting devices made with conducting polymers and small molecules. They are also useful for semiconducting devices made with nanocrystalline semiconductors. | 08-07-2014 |
20140163301 | Scanning Systems for Particle Cancer Therapy - A particle beam to treat malignant tissue is delivered to a patient by a gantry. The gantry includes a plurality of small magnets sequentially arranged along a beam tube to transfer the particle beam with strong focusing and a small dispersion function, whereby a beam size is very small, allowing for the small magnet size. Magnets arranged along the beam tube uses combined function magnets where the magnetic field is a combination of a bending dipole field with a focusing or defocusing quadrupole field. A triplet set of combined function magnets defines the beam size at the patient. A scanning system of magnets arranged along the beam tube after the bending system delivers the particle beam in a direction normal to the patient, to minimize healthy skin and tissue exposure to the particle beam. | 06-12-2014 |
20140141030 | CHIMERIC OSPA GENES, PROTEINS AND METHODS OF USE THEREOF - The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of | 05-22-2014 |
20140117513 | Production and Distribution of Dilute Species in Semiconducting Materials - Technologies are described effective to implement systems and methods of producing a material. The methods comprise receiving a tertiary semiconductor sample with a dilute species. The sample has two ends. The first end of the sample includes a first concentration of the dilute species lower than a second concentration of the dilute species in the second end of the sample. The method further comprises heating the sample in a chamber. The chamber has a first zone and a second zone. The first zone having a first temperature higher than a second temperature in the second zone. The sample is orientated such that the first end is in the first zone and the second end is in the second zone. | 05-01-2014 |
20140106258 | Truncated Ditetragonal Gold Prisms - Truncated ditetragonal gold prisms (Au TDPs) are synthesized by adding a dilute solution of gold seeds to a growth solution, and allowing the growth to proceed to completion. The Au TDPs exhibit the face-centered cubic crystal structure and are bounded by 12 high-index {310} facets. The Au TDPs may be used as heterogeneous catalysts as prepared, or may be used as substrates for subsequent deposition of an atomically thin layer of a platinum group metal catalyst. When the Au TDPs are used as substrates, the atomically thin layer of metal reproduces the high-index facets of the Au TDPs. | 04-17-2014 |
20140096483 | Transfer Chamber for Air-Sensitive Sample Processing - A transfer chamber is disclosed having a first plate with a first surface configured to receive a sample and a second surface containing a groove. The second surface of the first plate surrounds the first surface of the first plate. A second plate has a first surface and a second surface containing a groove. A sealing component is disposed in the groove of the first plate or the second plate. A pivotable link couples the first plate and the second plate. The pivotable link is configured to hold the first plate, the second plate, and the sealing component together to substantially create an air-tight seal between the first surface of the first plate and the second surface of the second plate. The pivotable link is configured to open the seal in response to a pressure differential across the transfer chamber. | 04-10-2014 |
20140084961 | Method and Apparatus for Analog Pulse Pile-Up Rejection - A method and apparatus for pulse pile-up rejection are disclosed. The apparatus comprises a delay value application constituent configured to receive a threshold-crossing time value, and provide an adjustable value according to a delay value and the threshold-crossing time value; and a comparison constituent configured to receive a peak-occurrence time value and the adjustable value, compare the peak-occurrence time value with the adjustable value, indicate pulse acceptance if the peak-occurrence time value is less than or equal to the adjustable value, and indicate pulse rejection if the peak-occurrence time value is greater than the adjustable value. | 03-27-2014 |
20140082775 | Modular UHV Compatible Angle Physical Contact Fiber Connection for Transferable Fiber Interferometer Type Dynamic Force Microscope Head - A modular transferable ultra-high vacuum compatible device has a body with a tunnel through its thickness. An interferometric sensor is mounted above the body and has a brace on which a cantilever is disposed and through which an optical fiber passes so that the two may be aligned prior to installation in an atomic force measurement apparatus. The sensor-mounted body is coupled to a mount for engaging an atomic force measurement apparatus to act as the interferometric head of the apparatus. | 03-20-2014 |
20140031573 | Enhancing Oil Accumulation in Vegetative Tissue of Plants - Combinations of genes are used to enhance the accumulation of triacylglycerol compounds in vegetative tissues of plants. Fatty acids in the form of triacylglycerol compounds accumulate in vegetative tissues in excess amounts compared to untreated plants. | 01-30-2014 |
20130324414 | SOLID-STATE CATALYSIS OF SUPERCONDUCTING CUPRATES - Catalytically active (001) ceria substrates or buffers are used to modify the structure of the epitaxial high temperature superconductor YBa | 12-05-2013 |
20130320295 | Vacuum Encapsulated, High Temperature Diamond Amplified Cathode Capsule and Method for Making Same - A vacuum encapsulated, hermetically sealed cathode capsule for generating an electron beam of secondary electrons, which generally includes a cathode element having a primary emission surface adapted to emit primary electrons, an annular insulating spacer, a diamond window element comprising a diamond material and having a secondary emission surface adapted to emit secondary electrons in response to primary electrons impinging on the diamond window element, a first high-temperature solder weld disposed between the diamond window element and the annular insulating spacer and a second high-temperature solder weld disposed between the annular insulating spacer and the cathode element. The cathode capsule is formed by a high temperature weld process under vacuum such that the first solder weld forms a hermetical seal between the diamond window element and the annular insulating spacer and the second solder weld forms a hermetical seal between the annular spacer and the cathode element whereby a vacuum encapsulated chamber is formed within the capsule. | 12-05-2013 |
20130316250 | Cubic Ionic Conductor Ceramics for Alkali Ion Batteries - The present invention relates to novel compositions, electrodes, electrochemical storage devices (batteries) and ionic conduction devices that use cubic ionic conductor (“CUBICON”) compounds, preferably nitridophosphate compounds. The cubic ionic conductor compound have a framework formula [MT | 11-28-2013 |
20130293987 | Quench Detection System for Superconducting Magnets - A quench detection device (or method) is provided that receives real-time information of concurrently monitored electrical characteristics of a high temperature superconducting (HTS) device, or any superconducting material, device, or system including low temperature superconductors, during operation. The quench detection device determines whether an electrical threshold is satisfied based on the received real-time information. The quench detection device detects a quench condition if the electrical threshold remains satisfied over a predetermined period of time or a predetermined successive number of times. If a quench detection is detected, the quench detection device sends a signal to terminate the operation of the HTS device. | 11-07-2013 |
20130281285 | MOLYBDENUM AND TUNGSTEN NANOSTRUCTURES AND METHODS FOR MAKING AND USING SAME - The present invention provides molybdenum and tungsten nanostructures, for example, nanosheets and nanoparticles, and methods of making and using same, including using such nanostructures as catlysts for hydrogen evolution reactions. | 10-24-2013 |
20130264198 | Synthesis of Nanoparticles Using Ethanol - The present disclosure relates to methods for producing nanoparticles. The nanoparticles may be made using ethanol as the solvent and the reductant to fabricate noble-metal nanoparticles with a narrow particle size distributions, and to coat a thin metal shell on other metal cores. With or without carbon supports, particle size is controlled by fine-tuning the reduction power of ethanol, by adjusting the temperature, and by adding an alkaline solution during syntheses. The thickness of the added or coated metal shell can be varied easily from sub-monolayer to multiple layers in a seed-mediated growth process. The entire synthesis of designed core-shell catalysts can be completed using metal salts as the precursors with more than 98% yield; and, substantially no cleaning processes are necessary apart from simple rinsing. Accordingly, this method is considered to be a “green” chemistry method. | 10-10-2013 |
20130225831 | Radio-methyl Vorozole and Methods for Making and Using the Same - Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity. | 08-29-2013 |
20130178357 | Method for Removing Strongly Adsorbed Surfactants and Capping Agents from Metal to Facilitate their Catalytic Applications - A method of synthesizing activated electrocatalyst, preferably having a morphology of a nanostructure, is disclosed. The method includes safely and efficiently removing surfactants and capping agents from the surface of the metal structures. With regard to metal nanoparticles, the method includes synthesis of nanoparticle(s) in polar or non-polar solution with surfactants or capping agents and subsequent activation by CO-adsorption-induced surfactant/capping agent desorption and electrochemical oxidation. The method produces activated macroparticle or nanoparticle electrocatalysts without damaging the surface of the electrocatalyst that includes breaking, increasing particle thickness or increasing the number of low coordination sites. | 07-11-2013 |
20130177838 | HOLLOW NANOPARTICLES AS ACTIVE AND DURABLE CATALYSTS AND METHODS FOR MANUFACTURING THE SAME - Hollow metal nanoparticles and methods for their manufacture are disclosed. In one embodiment the metal nanoparticles have a continuous and nonporous shell with a hollow core which induces surface smoothening and lattice contraction of the shell. In a particular embodiment, the hollow nanoparticles have an external diameter of less than 20 nm, a wall thickness of between 1 nm and 3 nm or, alternatively, a wall thickness of between 4 and 12 atomic layers. In another embodiment, the hollow nanoparticles are fabricated by a process in which a sacrificial core is coated with an ultrathin shell layer that encapsulates the entire core. Removal of the core produces contraction of the shell about the hollow interior. In a particular embodiment the shell is formed by galvanic displacement of core surface atoms while remaining core removal is accomplished by dissolution in acid solution or in an electrolyte during potential cycling between upper and lower applied potentials. | 07-11-2013 |
20130177715 | Platinum-Based Electrocatalysts Synthesized by Depositing Contiguous Adlayers on Carbon Nanostructures - High-surface-area carbon nanostructures coated with a smooth and conformal submonolayer-to-multilayer thin metal films and their method of manufacture are described. The manufacturing process may involve initial oxidation of the carbon nanostructures followed by immersion in a solution with the desired pH to create negative surface dipoles. The nanostructures are subsequently immersed in an alkaline solution containing non-noble metal ions which adsorb at surface reaction sites. The metal ions are then reduced via chemical or electrical means and the nanostructures are exposed to a solution containing a salt of one or more noble metals which replace adsorbed non-noble surface metal atoms by galvanic displacement. Subsequent film growth may be performed via the initial quasi-underpotential deposition of a non-noble metal followed by immersion in a solution comprising a more noble metal. The resulting coated nanostructures may be used, for example, as high-performance electrodes in supercapacitors, batteries, or other electric storage devices. | 07-11-2013 |
20130157133 | Process for Producing Defect-Free Lithium Metal Phosphate Electrode Materials - A method of synthesizing defect-free phospho-olivine materials is disclosed. The method is based on direct hydrothermal synthesis of phospho-olivine compound(s) and subsequent lattice reordering at or near the transition temperature to eliminate lattice defects or on one-pot in situ hydrothermal synthesis of phospho-olivine compound(s), where the cation ordering occurs during dwell time after rapid synthesis to eliminate lattice defects. The disclosed methods produce defect-free phospho-olivine compound(s) having a crystal lattice with a Pnma space group. In order to determine the exact transition temperature for complete removal of single- or mixed-transition metals from lithium sites or to monitor the crystal growth and removal of single- or mixed-transition metals from lithium sites during the hydrothermal synthesis, the method encompasses a procedure for determining and monitoring defects in the phospho-olivine phases using X-ray diffraction. | 06-20-2013 |
20130146843 | Segmented Nanowires Displaying Locally Controllable Properties - Vapor-liquid-solid growth of nanowires is tailored to achieve complex one-dimensional material geometries using phase diagrams determined for nanoscale materials. Segmented one-dimensional nanowires having constant composition display locally variable electronic band structures that are determined by the diameter of the nanowires. The unique electrical and optical properties of the segmented nanowires are exploited to form electronic and optoelectronic devices. Using gold-germanium as a model system, in situ transmission electron microscopy establishes, for nanometer-sized Au—Ge alloy drops at the tips of Ge nanowires (NWs), the parts of the phase diagram that determine their temperature-dependent equilibrium composition. The nanoscale phase diagram is then used to determine the exchange of material between the NW and the drop. The phase diagram for the nanoscale drop deviates significantly from that of the bulk alloy. | 06-13-2013 |
20130137602 | ARBITRARY ASSEMBLY OF NANO-OBJECTS INTO DESIGNED 1D AND 2D ARRAYS - The present invention is directed to nanoscale fabrication of nano-materials with application in electronics, energy conversion, bio-sensing and others. Specifically, the invention is directed to arbitrary, that is periodic and non-periodic, assembly of nano-objects on I D and 2D arrays. The present invention utilizes self-organization properties of nanoscale bio-encoded building blocks, programmability of biomolecular interactions, and simple processing techniques for providing arbitrary by-design fabrication capability. Specifically, the present invention utilizes double stranded DNA attached to a surface and intercalating PNA-DNA hybrids attached to nano-objects to bind the nano-objects to the dsDNA in a site specific manner. The present invention allows for an integration of a large number of nano-components in unified well-defined systems. Accordingly, the present invention is applicable for fabrication of I D and 2D structures of various by-design placements of nano-objects of multiple types, including metal, semiconducting and organic nano-objects. | 05-30-2013 |
20130126746 | ARRAY OF VIRTUAL FRISCH-GRID DETECTORS WITH COMMON CATHODE AND REDUCED LENGTH OF SHIELDING ELECTRODES - A novel radiation detector system is disclosed that solves the electron trapping problem by optimizing shielding of the individual virtual Frisch-grid detectors in an array configuration. | 05-23-2013 |
20130056359 | APPARATUS AND METHOD FOR THE SYNTHESIS AND TREATMENT OF METAL MONOLAYER ELECTROCATALYST PARTICLES IN BATCH OR CONTINUOUS FASHION - An apparatus and method for the synthesis and treatment of electrocatalyst particles in batch or continuous fashion is provided. In one embodiment, the apparatus is comprised of a three-electrode cell which includes a reference electrode, a counter electrode, and a working electrode. The working electrode is preferably a cylindrical vessel having an electrically conductive region. The electrode assembly is introduced into a slurry containing metal ions and a plurality of particles. During operation an electrical potential is applied and the working electrode is rotated at a predetermined speed. When particles in the slurry collide with the electrically conductive region the transferred charge facilitates deposition of an ad-layer of the desired metal. In this manner film growth can commence on a large number of particles simultaneously. This process is especially suitable as a commercial thin film deposition process for forming catalytically active layers on nanoparticles for use in energy conversion devices. | 03-07-2013 |
20130045328 | Electrodes Synthesized from Carbon Nanostructures Coated with a Smooth and Conformal Metal Adlayer - High-surface-area carbon nanostructures coated with a smooth and conformal submonolayer-to-multilayer thin metal films and their method of manufacture are described. The preferred manufacturing process involves the initial oxidation of the carbon nanostructures followed by a surface preparation process involving immersion in a solution with the desired pH to create negative surface dipoles. The nanostructures are subsequently immersed in an alkaline solution containing a suitable quantity of non-noble metal ions which adsorb at surface reaction sites. The metal ions are then reduced via chemical or electrical means. The nanostructures are exposed to a solution containing a salt of one or more noble metals which replace adsorbed non-noble surface metal atoms by galvanic displacement. The process can be controlled and repeated to obtain a desired film coverage. The resulting coated nanostructures may be used, for example, as high-performance electrodes in supercapacitors, batteries, or other electric storage devices. | 02-21-2013 |
20130045151 | C-11 Cyanide Production System - A method for providing | 02-21-2013 |
20130040343 | Methods for Detection of Methyl-CpG Dinucleotides - The invention provides methods for enriching methyl-CpG sequences from a DNA sample. The method makes use of conversion of cytosine residues to uracil under conditions in which methyl-cytosine residues are preserved. Additional methods of the invention enable to preservation of the context of me-CpG dinucleotides. The invention also provides a recombinant, full length and substantially pure McrA protein (rMcrA) for binding and isolation of DNA fragments containing the sequence 5′-C | 02-14-2013 |
20130035236 | Fluorinated Precursors of Superconducting Ceramics, and Methods of Making the Same - This invention provides a method of making a fluorinated precursor of a superconducting ceramic. The method comprises providing a solution comprising a rare earth salt, an alkaline earth metal salt and a copper salt; spraying the solution onto a substrate to provide a film-covered substrate; and heating the film-covered substrate in an atmosphere containing fluorinated gas to provide the fluorinated precursor. | 02-07-2013 |
20130014818 | Conductive Polymer/Fullerence Blend Thin Films with Honeycomb Framework for Transparent Photovoltaic Application - Optoelectronic devices and thin-film semiconductor compositions and methods for making same are disclosed. The methods provide for the synthesis of the disclosed composition. The thin-film semiconductor compositions disclosed herein have a unique configuration that exhibits efficient photo-induced charge transfer and high transparency to visible light. | 01-17-2013 |
20130004419 | Carbonylporphyrins and Uses Thereof - The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET. | 01-03-2013 |
20120314827 | System for Active Long Range Detection and Identification of Special Nuclear Materials Using a High Intensity Particle Beam - A long-range method and a system for reliably detecting and identifying special nuclear materials is provided that relies on the emission of delayed neutrons present in the decay of fission products (delayed neutron precursors) as a unique signature for the special nuclear materials, such as highly enriched uranium ( | 12-13-2012 |
20120313323 | Quark Matter Card Games - The disclosed Quark matter card game and methods of playing with cards represent elementary particles which provides first-hand, fun, attractive and enjoyable experience for laypersons such as for example, children, students and researchers to have a hands-on experience of particle and high energy heavy ion or nuclear physics using simple and inexpensive tools. Anyone who knows the colors, red, green, blue, black and white, can start to play one of the games described herein. According an embodiment, the disclosed card game is directed to a deck for playing an educational game, the deck comprises a plurality of card-like devices having a face bearing a representation of an elementary particle. | 12-13-2012 |
20120313003 | Gantry for Medical Particle Therapy Facility - A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of superconducting, variable field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of variable field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing variable field magnets. | 12-13-2012 |
20120293791 | Sample Holder with Optical Features for Holding a Sample in an Analytical Device for Research Purposes - A method for performing time resolved imaging, spectroscopy or diffraction techniques involving a sample held in an analytical device. The method generally includes supporting a sample within an analytical device with a sample holder, conveying a light beam through an internal conduit of a sample holder body of the sample holder and directing the light beam between the sample holder body and the sample with a first light beam positioner of a sample support member of the sample holder, such that the light beam and an energy pulse emitted by an energy source of the analytical device converge on the sample supported by the sample holder within the analytical device. | 11-22-2012 |
20120293351 | Method and Apparatus for Low Power Analog-to-Digital Conversion - A method and apparatus for analog-to-digital conversion. An Analog-to-Digital Converter (ADC) includes M ADC | 11-22-2012 |
20120288433 | Processing of Monolayer Materials Via Interfacial Reactions - A method of forming and processing of graphene is disclosed based on exposure and selective intercalation of the partially graphene-covered metal substrate with atomic or molecular intercalation species such as oxygen (O | 11-15-2012 |
20120270737 | Stable and Metastable Nanowires Displaying Locally Controllable Properties - Vapor-liquid-solid growth of nanowires is tailored to achieve complex one-dimensional material geometries using phase diagrams determined for nanoscale materials. Segmented one-dimensional nanowires having constant composition display locally variable electronic band structures that are determined by the diameter of the nanowires. The unique electrical and optical properties of the segmented nanowires are exploited to form electronic and optoelectronic devices. Using gold-germanium as a model system, in situ transmission electron microscopy establishes, for nanometer-sized Au—Ge alloy drops at the tips of Ge nanowires (NWs), the parts of the phase diagram that determine their temperature-dependent equilibrium composition. The nanoscale phase diagram is then used to determine the exchange of material between the NW and the drop. The phase diagram for the nanoscale drop deviates significantly from that of the bulk alloy. | 10-25-2012 |
20120269053 | Co-Scheduling of Network Resource Provisioning and Host-to-Host Bandwidth Reservation on High-Performance Network and Storage Systems - A cross-domain network resource reservation scheduler configured to schedule a path from at least one end-site includes a management plane device configured to monitor and provide information representing at least one of functionality, performance, faults, and fault recovery associated with a network resource; a control plane device configured to at least one of schedule the network resource, provision local area network quality of service, provision local area network bandwidth, and provision wide area network bandwidth; and a service plane device configured to interface with the control plane device to reserve the network resource based on a reservation request and the information from the management plane device. Corresponding methods and computer-readable medium are also disclosed. | 10-25-2012 |
20120251887 | Carbon-Coated Magneli-Phase TinO2n-1 Nanomaterials and a Method of Synthesis Thereof - A novel Magnéli phase nanomaterial with carbon coating is disclosed. The present Magnéli phase material, which can form a nanowire, a nanobelt, a nanoparticle, a nanocrystal, or a nanosheet, includes at least a Magnéli phase core having a substoichiometric composition of titanium oxide having a formula Ti | 10-04-2012 |
20120245019 | Method and Electrochemical Cell for Synthesis of Electrocatalysts by Growing Metal Monolayers, or Bilayers and Treatment of Metal, Carbon, Oxide and Core-Shell Nanoparticles - An apparatus and method for the synthesis and treatment of electrocatalyst particles in batch or continuous fashion is provided. In one embodiment, the apparatus is comprised of a three-electrode cell which includes a cell body electrode, a reference electrode, and a counter electrode. A slurry containing non-noble metal ions and a plurality of particles is introduced into the apparatus. During operation an electrical potential is applied and the slurry is stirred. When particles in the slurry collide with the electrically conductive region of the cell body electrode the transferred charge facilitates deposition of an adlayer of the desired metal. In this manner film growth can commence on a large number of particles simultaneously. After the non-noble metal ions are deposited onto the particles, they are displaced by noble-metal ions by galvanic displacement. This process is especially suitable for forming catalytically active layers on nanoparticles for use in energy conversion devices. | 09-27-2012 |
20120245017 | Method and Electrochemical Cell for Synthesis and Treatment of Metal Monolayer Electrocatalysts Metal, Carbon, and Oxide Nanoparticles Ion Batch, or in Continuous Fashion - An apparatus and method for synthesis and treatment of electrocatalyst particles in batch or continuous fashion is provided. In one embodiment, the apparatus comprises a sonication bath and a two-compartment chamber submerged in the sonication bath. The upper and lower compartments are separated by a microporous material surface. The upper compartment comprises a cover and a working electrode (WE) connected to a Pt foil contact, with the foil contact connected to the microporous material. The upper chamber further comprises reference counter electrodes. The lower compartment comprises an electrochemical cell containing a solution of metal ions. In one embodiment, the method for synthesis of electrocatalysts comprises introducing a plurality of particles into the apparatus and applying sonication and an electrical potential to the microporous material connected to the WE. After the non-noble metal ions are deposited onto the particles, the non-noble metal ions are displaced by noble-metal ions by galvanic displacement. | 09-27-2012 |
20120219942 | Methods Employing McrA to Detect 5-Methyl Cytosine - The invention provides methods for using the rMcrA protein, and derivatives thereof, for direct or semi-direct determination of the methylation status of CpG dinucleotides in methyl-CpG island sequences of interest. | 08-30-2012 |
20120211668 | Beam Current Controller for Laser Ion Source - The present invention relates to the design and use of an ion source with a rapid beam current controller for experimental and medicinal purposes. More particularly, the present invention relates to the design and use of a laser ion source with a magnetic field applied to confine a plasma flux caused by laser ablation. | 08-23-2012 |
20120205785 | Technique for Etching Monolayer and Multilayer Materials - A process is disclosed for sectioning by etching of monolayers and multilayers using an RIE technique with fluorine-based chemistry. In one embodiment, the process uses Reactive Ion Etching (RIE) alone or in combination with Inductively Coupled Plasma (ICP) using fluorine-based chemistry alone and using sufficient power to provide high ion energy to increase the etching rate and to obtain deeper anisotropic etching. In a second embodiment, a process is provided for sectioning of WSi | 08-16-2012 |
20120187373 | Stepwise Surface Assembly of Quantum Dot-Fullerene Heterodimers - The present invention relates to high-purity quantum dot-fullerene dimers with controllable linker length and the process of fabricating the same. More particularly, this invention relates to the design, synthesis, and application of high-purity quantum dot-fullerene dimers by applying a novel stepwise surface assembly procedure that ensures the formation of conjugates due to steric repulsion effects between the quantum dots. | 07-26-2012 |
20120183866 | Fluorinated Arylboron Oxalate as Anion Receptors and Additives for Non-Aqueous Battery Electrolytes - The present invention relates to electrochemical storage devices containing a non-aqueous lithium based electrolyte with high ionic conductivity, low impedance, and high thermal stability. More particularly, this invention relates to the design, synthesis and application of novel fluorinated arylboron oxalate based compounds which act as anion receptors and/or additives for non-aqueous batteries. When used as an anion receptor for non-aqueous battery electrolytes, the fluorinated arylboron oxalate enhances conductivity, lithium ion transference number and Solid Electrolyte Interface (SEI) formation capability during the formation cycling. | 07-19-2012 |
20120181435 | Detection System for High-Resolution Gamma Radiation Spectroscopy with Neutron Time-of-Flight Filtering - A γ-radiation detection system that includes at least one semiconductor detector such as HPGe-Detector, a position-sensitive α-Detector, a TOF Controller, and a Digitizer/Integrator. The Digitizer/Integrator starts to process the energy signals of a γ-radiation sent from the HPGe-Detector instantly when the HPGe-Detector detects the γ-radiation. Subsequently, it is determined whether a coincidence exists between the α-particles and γ-radiation signal, based on a determination of the time-of-flight of neutrons obtained from the α-Detector and the HPGe-Detector. If it is determined that the time-of-flight falls within a predetermined coincidence window, the Digitizer/Integrator is allowed to continue and complete the energy signal processing. If, however, there is no coincidence, the Digitizer/Integrator is instructed to be clear and reset its operation instantly. | 07-19-2012 |
20120145897 | Transmission Electron Microscope Sample Holder with Optical Features - A sample holder for holding a sample to be observed for research purposes, particularly in a transmission electron microscope (TEM), generally includes an external alignment part for directing a light beam in a predetermined beam direction, a sample holder body in optical communication with the external alignment part and a sample support member disposed at a distal end of the sample holder body opposite the external alignment part for holding a sample to be analyzed. The sample holder body defines an internal conduit for the light beam and the sample support member includes a light beam positioner for directing the light beam between the sample holder body and the sample held by the sample support member. | 06-14-2012 |
20120141797 | Zwitterion-Linker Coatings for Nano-objects in Solutions of Multivalent Counterions - The disclosure is directed to nanoparticles used in creating nanostructure complexes in the presence of divalent cations. In particular, the disclosure is directed to nanoparticles that are coated with zwitterions and linker portions in a manner that facilitates nanostructure complex assembly while reducing or preventing non-specific spontaneous aggregation of nanoparticle in the presence of divalent cations. The disclosure also provides a method for preparing a nanoparticle coating of the present invention. Furthermore, the disclosure provides a method for assembling nanostructure complexes using coated nanoparticles with a scaffold. | 06-07-2012 |
20120129826 | Method of Treating Depression - Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K | 05-24-2012 |
20120121050 | Method and Apparatus for Analog Pulse Pile-Up Rejection - A method and apparatus for pulse pile-up rejection are disclosed. The apparatus comprises a delay value application constituent configured to receive a threshold-crossing time value, and provide an adjustable value according to a delay value and the threshold-crossing time value; and a comparison constituent configured to receive a peak-occurrence time value and the adjustable value, compare the peak-occurrence time value with the adjustable value, indicate pulse acceptance if the peak-occurrence time value is less than or equal to the adjustable value, and indicate pulse rejection if the peak-occurrence time value is greater than the adjustable value. | 05-17-2012 |
20120117694 | Novel Monolignol 4-O-Methyltransferases and Uses Thereof - Modified (iso)eugenol 4-O-methyltransferase enzymes having novel capacity for methylation of monolignols and reduction of lignin polymerization in plant cell wall are disclosed. Sequences encoding the modified enzymes are disclosed. | 05-10-2012 |
20120063569 | Two-Axis Sagittal Focusing Monochromator - An x-ray focusing device and method for adjustably focusing x-rays in two orthogonal directions simultaneously. The device and method can be operated remotely using two pairs of orthogonal benders mounted on a rigid, open frame such that x-rays may pass through the opening in the frame. The added x-ray flux allows significantly higher brightness from the same x-ray source. | 03-15-2012 |
20120039446 | INTERWOVEN MULTI-APERTURE COLLIMATOR FOR 3-DIMENSIONAL RADIATION IMAGING APPLICATIONS - An interwoven multi-aperture collimator for three-dimension radiation imaging applications is disclosed. The collimator comprises a collimator body including a plurality of apertures disposed in a two-dimensional grid. The collimator body is configured to absorb and collimate radiation beams emitted from a radiation source within a field of view of said collimator. The collimator body has a surface plane disposed closest to the radiation source. The two-dimensional grid is selectively divided into at least a first and a second group of apertures, respectively defining at least a first view and a second view of an object to be imaged. The first group of apertures is formed by interleaving or alternating rows of the grid, and the second group of apertures is formed by the rows of apertures adjacent to the rows of the first group. Each aperture in the first group is arranged in a first orientation angle with respect to the surface plane of said collimator body, and each aperture in the second group is arranged in a second orientation angle with respect to the surface plane of said collimator body such that the apertures of the first group are interwoven with the apertures of the second group. | 02-16-2012 |
20120028191 | Azide Functionalized Poly(3-Hexylthiophene) and Method of Forming Same - The invention relates azide functionalized poly(3-hexylthiophene)s. Various azide functionalized poly(3-hexylthiophene)s and intermediates are disclosed and described, as well as method for making novel monomers that are synthesized and transformed into P3HT-N | 02-02-2012 |
20110321194 | ACCUMULATION OF OMEGA-7 FATTY ACIDS IN PLANT SEEDS - Compositions and methods include genetically encoding and expressing a novel Δ | 12-29-2011 |
20110286576 | Compact Endocavity Diagnostic Probes for Nuclear Radiation Detection - This invention relates to the field of radiation imaging. In particular, the invention relates to an apparatus and a method for imaging tissue or an inanimate object using a novel probe that has an integrated solid-state semiconductor detector and complete readout electronics circuitry. | 11-24-2011 |
20110272589 | Hybrid Anode for Semiconductor Radiation Detectors - The present invention relates to a novel hybrid anode configuration for a radiation detector that effectively reduces the edge effect of surface defects on the internal electric field in compound semiconductor detectors by focusing the internal electric field of the detector and redirecting drifting carriers away from the side surfaces of the semiconductor toward the collection electrode(s). | 11-10-2011 |
20110245465 | Methods for Detection of Methyl-CpG Dinucleotides - The invention provides methods for enriching methyl-CpG sequences from a DNA sample. The method makes use of conversion of cytosine residues to uracil under conditions in which methyl-cytosine residues are preserved. Additional methods of the invention enable to preservation of the context of me-CpG dinucleotides. The invention also provides a recombinant, full length and substantially pure McrA protein (rMcrA) for binding and isolation of DNA fragments containing the sequence 5′-C | 10-06-2011 |
20110151356 | Electrocatalyst for Oxygen Reduction with Reduced Platinum Oxidation and Dissolution Rates - The invention relates to platinum-metal oxide composite particles and their use as electrocatalysts in oxygen-reducing cathodes and fuel cells. The invention particularly relates to methods for preventing the oxidation of the platinum electrocatalyst in the cathodes of fuel cells by use of these platinum-metal oxide composite particles. The invention additionally relates to methods for producing electrical energy by supplying such a fuel cell with an oxidant, such as oxygen, and a fuel source, such as hydrogen. | 06-23-2011 |
20110120517 | Synthesis of High-Efficiency Thermoelectric Materials - A process for the fabrication of high efficiency thermoelectric materials using non-equilibrium synthesis routes is described. In one embodiment a molten alloy comprising a predetermined ratio of elements which will constitute the thermoelectric material is quenched at a cooling rate in excess of, for example, 10 | 05-26-2011 |
20110116092 | Wide Size Range Fast Integrated Mobility Spectrometer - A mobility spectrometer to measure a nanometer particle size distribution is disclosed. The mobility spectrometer includes a conduit and a detector. The conduit is configured to receive and provide fluid communication of a fluid stream having a charged nanometer particle mixture. The conduit includes a separator section configured to generate an electrical field of two dimensions transverse to a dimension associated with the flow of the charged nanometer particle mixture through the separator section to spatially separate charged nanometer particles of the charged nanometer particle mixture in said two dimensions. The detector is disposed downstream of the conduit to detect concentration and position of the spatially-separated nanometer particles. | 05-19-2011 |
20100276731 | Inorganic Nanocrystal Bulk Heterojunctions - A bulk heterojunction comprising an intermixed blend of fully inorganic n- and p-type particles and its method of manufacture are described. The particles are preferably nanometer-scale, spherical-shaped particles known as nanocrystals which are assembled into a densely packed three-dimensional array. The nanocrystals are preferably fabricated from a photo-active material which, in combination with the nanocrystal shape and size, can be engineered to produce a bulk heterojunction with a specific absorption spectrum. The bulk heterojunction is preferably formed by dispersing a predetermined ratio of the desired n- and p-type nanocrystals in an organic solvent and employing low-cost solution processing techniques to deposit a film having the desired thickness, relative concentration of nanocrystal types, and degree of intermixing onto a substrate. When incorporated as the active layer in optoelectronic devices such solar cells, fully inorganic bulk heterojunctions offer significant improvements in performance while maintaining the low costs associated with organic processing techniques. | 11-04-2010 |
20100230620 | Achromatic and Uncoupled Medical Gantry - A medical gantry that focus the beam from the beginning of the gantry to the exit of the gantry independent of the rotation angle of the gantry by keeping the beam achromatic and uncoupled, thus, avoiding the use of collimators or rotators, or additional equipment to control the beam divergence, which may cause beam intensity loss or additional time in irradiation of the patient, or disadvantageously increase the overall gantry size inapplicable for the use in the medical treatment facility. | 09-16-2010 |
20100216632 | High Stability, Self-Protecting Electrocatalyst Particles - High-stability, self-protecting particles encapsulated by a thin film of a catalytically active noble metal are described. The particles are preferably nanoparticles comprising a passivating element having at least one metal selected from the group consisting of columns IVB, VB, VIB, and VIIB of the periodic table. The nanoparticle is preferably encapsulated by a Pt shell and may be either a nanoparticle alloy or a core-shell nanoparticle. The nanoparticle alloys preferably have a core comprised of a passivating component alloyed with at least one other transition metal. The core-shell nanoparticles comprise a core of a non-noble metal surrounded by a shell of a noble metal. The material constituting the core, shell, or both the core and shell may be alloyed with one or more passivating elements. The self-protecting particles are ideal for use in corrosive environments where they exhibit improved stability compared to conventional electrocatalyst particles. | 08-26-2010 |
20100197490 | Platinum-Coated Non-Noble Metal-Noble Metal Core-Shell Electrocatalysts - Core-shell particles encapsulated by a thin film of a catalytically active metal are described. The particles are preferably nanoparticles comprising a non-noble core with a noble metal shell which preferably do not include Pt. The non-noble metal-noble metal core-shell nanoparticles are encapsulated by a catalytically active metal which is preferably Pt. The core-shell nanoparticles are preferably formed by prolonged elevated-temperature annealing of nanoparticle alloys in an inert environment. This causes the noble metal component to surface segregate and form an atomically thin shell. The Pt overlayer is formed by a process involving the underpotential deposition of a monolayer of a non-noble metal followed by immersion in a solution comprising a Pt salt. A thin Pt layer forms via the galvanic displacement of non-noble surface atoms by more noble Pt atoms in the salt. The overall process is a robust and cost-efficient method for forming Pt-coated non-noble metal-noble metal core-shell nanoparticles. | 08-05-2010 |
20100177462 | Platinum-Based Electrocatalysts Synthesized by Depositing Contiguous Adlayers on Carbon Nanostructures - High-surface-area carbon nanostructures coated with a smooth and conformal submonolayer-to-multilayer thin metal films and their method of manufacture are described. The preferred manufacturing process involves the initial oxidation of the carbon nanostructures followed by immersion in a solution with the desired pH to create negative surface dipoles. The nanostructures are subsequently immersed in an alkaline solution containing non-noble metal ions which adsorb at surface reaction sites. The metal ions are then reduced via chemical or electrical means and the nanostructures are exposed to a solution containing a salt of one or more noble metals which replace adsorbed non-noble surface metal atoms by galvanic displacement. Subsequent film growth may be performed via the initial quasi-underpotential deposition of a non-noble metal followed by immersion in a solution comprising a more noble metal. The resulting coated nanostructures may be used, for example, as high-performance electrodes in supercapacitors, batteries, or other electric storage devices. | 07-15-2010 |
20100171096 | Segmented Nanowires Displaying Locally Controllable Properties - Vapor-liquid-solid growth of nanowires is tailored to achieve complex one-dimensional material geometries using phase diagrams determined for nanoscale materials. Segmented one-dimensional nanowires having constant composition display locally variable electronic band structures that are determined by the diameter of the nanowires. The unique electrical and optical properties of the segmented nanowires are exploited to form electronic and optoelectronic devices. Using gold-germanium as a model system, in situ transmission electron microscopy establishes, for nanometer-sized Au—Ge alloy drops at the tips of Ge nanowires (NWs), the parts of the phase diagram that determine their temperature-dependent equilibrium composition. The nanoscale phase diagram is then used to determine the exchange of material between the NW and the drop. The phase diagram for the nanoscale drop deviates significantly from that of the bulk alloy. | 07-08-2010 |
20100160300 | Method of Treating Depression - Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K | 06-24-2010 |
20100159618 | Assembly of ordered carbon shells on semiconducting nanomaterials - In some embodiments of the invention, encapsulated semiconducting nanomaterials are described. In certain embodiments the nanostructures described are semiconducting nanomaterials encapsulated with ordered carbon shells. In some aspects a method for producing encapsulated semiconducting nanomaterials is disclosed. In some embodiments applications of encapsulated semiconducting nanomaterials are described. | 06-24-2010 |
20100144029 | Facilitating Protein Solubility by Use of Peptide Extensions - Expression vectors for expression of a protein or polypeptide of interest as a fusion product composed of the protein or polypeptide of interest fused at one terminus to a solubility enhancing peptide extension are provided. Sequences encoding the peptide extensions are provided. The invention further comprises antibodies which bind specifically to one or more of the solubility enhancing peptide extensions. | 06-10-2010 |
20100102248 | Transmission Electron Microscope Sample Holder with Optical Features - A sample holder for holding a sample to be observed for research purposes, particularly in a transmission electron microscope (TEM), generally includes an external alignment part for directing a light beam in a predetermined beam direction, a sample holder body in optical communication with the external alignment part and a sample support member disposed at a distal end of the sample holder body opposite the external alignment part for holding a sample to be analyzed. The sample holder body defines an internal conduit for the light beam and the sample support member includes a light beam positioner for directing the light beam between the sample holder body and the sample held by the sample support member. | 04-29-2010 |
20100099012 | Electrocatalyst Synthesized by Depositing a Contiguous Metal Adlayer on Transition Metal Nanostructures - Transition metal nanostructures coated with a contiguous, conformal submonolayer-to-multilayer noble metal film and their method of manufacture are described. The manufacturing process involves the initial formation of suitably sized transition metal or alloy nanostructures which may be nanorods, nanobars, or nanowires. A monolayer of a non-noble metal is deposited onto the surface of the nanostructures by underpotential deposition. This is followed by the galvanic displacement of the non-noble metal by a second metal to yield a conformal coating of a monolayer of the second metal on the surface of the nanostructures. The replacement of atoms of the first metal by atoms of the second metal is an irreversible and spontaneous redox reaction which involves the replacement of a non noble metal by a more noble metal. The process can be controlled and repeated to obtain the desired film coverage. The resulting coated nanostructures provide heightened catalytic activity and can be used as high-performance electrodes in fuel cells. | 04-22-2010 |
20100097742 | Electrodes Synthesized from Carbon Nanostructures Coated with a Smooth and Conformal Metal Adlayer - High-surface-area carbon nanostructures coated with a smooth and conformal submonolayer-to-multilayer thin metal films and their method of manufacture are described. The preferred manufacturing process involves the initial oxidation of the carbon nanostructures followed by a surface preparation process involving immersion in a solution with the desired pH to create negative surface dipoles. The nanostructures are subsequently immersed in an alkaline solution containing a suitable quantity of non-noble metal ions which adsorb at surface reaction sites. The metal ions are then reduced via chemical or electrical means. The nanostructures are exposed to a solution containing a salt of one or more noble metals which replace adsorbed non-noble surface metal atoms by galvanic displacement. The process can be controlled and repeated to obtain a desired film coverage. The resulting coated nanostructures may be used, for example, as high-performance electrodes in supercapacitors, batteries, or other electric storage devices. | 04-22-2010 |
20100081174 | Methods for Detection of Methyl-CpG Dinucleotides - The invention provides methods for enriching methyl-CpG sequences from a DNA sample. The method makes use of conversion of cytosine residues to uracil under conditions in which methyl-cytosine residues are preserved. Additional methods of the invention enable to preservation of the context of me-CpG dinucleotides. The invention also provides a recombinant, full length and substantially pure McrA protein (rMcrA) for binding and isolation of DNA fragments containing the sequence 5′-C | 04-01-2010 |
20100051818 | Method and Apparatus for the Measurement of Signals from Radiation Sensors - The preferred embodiments of the present invention include a device for measuring an ionizing event in a radiation sensor. The device can include a charge amplifier and a timing shaper. The charge amplifier receives a cathode signal and is configured to output an amplified cathode signal. The timing shaper is operatively connected to the charge amplifier to receive the amplified cathode signal. The timing shaper is configured to generate a first pulse in response to a beginning of the ionizing event and a second pulse in response to an end of the ionizing event. The first and second pulses are associated with a depth of interaction of the ionizing event and are generated in response to a slope of the amplified cathode signal changing. | 03-04-2010 |
20100049459 | High Dynamic Range Charge Measurements - A charge amplifier for use in radiation sensing includes an amplifier, at least one switch, and at least one capacitor. The switch selectively couples the input of the switch to one of at least two voltages. The capacitor is electrically coupled in series between the input of the amplifier and the input of the switch. The capacitor is electrically coupled to the input of the amplifier without a switch coupled therebetween. A method of measuring charge in radiation sensing includes selectively diverting charge from an input of an amplifier to an input of at least one capacitor by selectively coupling an output of the at least one capacitor to one of at least two voltages. The input of the at least one capacitor is operatively coupled to the input of the amplifier without a switch coupled therebetween. The method also includes calculating a total charge based on a sum of the amplified charge and the diverted charge. | 02-25-2010 |
20100038552 | Gantry for Medical Particle Therapy Facility - A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of fixed field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of fixed field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing fixed field magnets. | 02-18-2010 |
20100037674 | Test Surfaces Useful for Calibration of Surface Profilometers - The present invention provides for test surfaces and methods for calibration of surface profilometers, including interferometric and atomic force microscopes. Calibration is performed using a specially designed test surface, or the Binary Pseudo-random (BPR) grating (array). Utilizing the BPR grating (array) to measure the power spectral density (PSD) spectrum, the profilometer is calibrated by determining the instrumental modulation transfer function (IMTF). | 02-18-2010 |
20100021471 | CARBON NANOTUBE-BASED DRUG DELIVERY SYSTEMS AND METHODS OF MAKING SAME - The present invention includes a conjugates comprising a carbon nanotube with at least one covalently attached recognition module, and at least one covalently attached pharmaceutical compound or a precursor of the pharmaceutical compound, | 01-28-2010 |
20100012851 | Multi-Anode Ionization Chamber - The present invention includes a high-energy detector having a cathode chamber, a support member, and anode segments. The cathode chamber extends along a longitudinal axis. The support member is fixed within the cathode chamber and extends from the first end of the cathode chamber to the second end of the cathode chamber. The anode segments are supported by the support member and are spaced along the longitudinal surface of the support member. The anode segments are configured to generate at least a first electrical signal in response to electrons impinging thereon. | 01-21-2010 |
20100004133 | Fluorinated Precursors of Superconducting Ceramics, and Methods of Making the Same - This invention provides a method of making a fluorinated precursor of a superconducting ceramic. The method comprises providing a solution comprising a rare earth salt, an alkaline earth metal salt and a copper salt; spraying the solution onto a substrate to provide a film-covered substrate; and heating the film-covered substrate in an atmosphere containing fluorinated gas to provide the fluorinated precursor. | 01-07-2010 |
20090317880 | Simple, Rapid Method for the Preparation of Isotopically Labeled Formaldehyde - Isotopically labeled formaldehyde (*C | 12-24-2009 |
20090302232 | MULTI-WINDOW SIGNAL PROCESSING ELECTRONICS ARCHITECTURE FOR PHOTON COUNTING WITH MULTI-ELEMENT SENSORS - A radiation detection and counting system ( | 12-10-2009 |
20090291045 | Regeneration of Aluminum Hydride - The present invention provides methods and materials for the formation of hydrogen storage alanes, AlH | 11-26-2009 |
20090275465 | DNA-Guided Nanoparticle Assemblies - In some embodiments, DNA-capped nanoparticles are used to define a degree of crystalline order in assemblies thereof. In some embodiments, thermodynamically reversible and stable body-centered cubic (bcc) structures, with particles occupying <˜10% of the unit cell, are formed. Designs and pathways amenable to the crystallization of particle assemblies are identified. In some embodiments, a plasmonic crystal is provided. In some aspects, a method for controlling the properties of particle assemblages is provided. In some embodiments a catalyst is formed from nanoparticles linked by nucleic acid sequences and forming an open crystal structure with catalytically active agents attached to the crystal on its surface or in interstices. | 11-05-2009 |
20090258355 | Nanoscale Clusters and Methods of Making Same - The present invention is a method of making a nanocluster. The method comprises providing a surface comprising at least one anchoring biomolecule, wherein the surface is in a solution; adding an initial recognition-nano-component to the solution wherein the initial recognition-nano-component comprises i) a nanoparticle and one specifically-bindable-biomolecule, or ii) a nanoparticle and two different types of specifically-bindable-biomolecules, wherein a biomolecule of the initial recognition-nano-component specifically binds to the anchoring biomolecule; and adding a releasing biomolecule to the solution, wherein the releasing biomolecule binds to the anchoring biomolecule with a greater binding strength than the anchoring biomolecule binds to the initial recognition-nano-component, or wherein the releasing biomolecule binds to the initial recognition-nano-component with a greater binding strength than anchoring biomolecule binds to the initial recognition-nano-component, thereby making a nanocluster. | 10-15-2009 |
20090258051 | Microbes Encapsulated Within Crosslinkable Polymers - The invention relates to porous films comprising crosslinked electrospun hydrogel fibers. Viable microbes are encapsulated within the crosslinked electrospun hydrogel fibers. The crosslinked electrospun hydrogel fibers are water insoluble and permeable. The invention also relates to methods of making and using such porous films. | 10-15-2009 |
20090253190 | Enhanced Metabolite Generation - The present invention relates to the enhanced production of metabolites by a process whereby a carbon source is oxidized with a fermentative microbe in a compartment having a portal. An electron acceptor is added to the compartment to assist the microbe in the removal of excess electrons. The electron acceptor accepts electrons from the microbe after oxidation of the carbon source. Other transfers of electrons can take place to enhance the production of the metabolite, such as acids, biofuels or brewed beverages. | 10-08-2009 |
20090177025 | Mercury Contamination Extraction - Mercury is removed from contaminated waste by firstly applying a sulfur reagent to the waste. Mercury in the waste is then permitted to migrate to the reagent and is stabilized in a mercury sulfide compound. The stable compound may then be removed from the waste which itself remains in situ following mercury removal therefrom. | 07-09-2009 |
20090171592 | Homology Models of Mammalian Zinc Transporters and Methods of Using Same - The present invention is a method of identifying a compound that has a sufficient level of binding with a target site on a mammalian zinc transporter, or a portion thereof. The method comprises (a) providing a homology model of a mammalian zinc transporter, or portion thereof, comprising at least one target site; and (b) employing computational means to evaluate the level of binding of the compound with the target site, or a portion thereof. If a sufficient level of binding is found, then a compound is identified. | 07-02-2009 |
20090137398 | High Temperature Interfacial Superconductivity - High-temperature superconductivity confined to nanometer-scale interfaces has been a long standing goal because of potential applications in electronic devices. The spontaneous formation of a superconducting interface in bilayers consisting of an insulator (La | 05-28-2009 |
20090117384 | Titania Nanocavities and Method of Making - Disclosed herein are compositions of metal oxide nanoparticles having regular polyhedral nanocavities, where the metal oxide can be titania, and where the nanoparticles be nanorods. Also disclosed are titania nanoparticles with nanocavities that are doped with dopants. Methods of making metal oxide nanoparticles with nanocavities are also disclosed. Also disclosed are ultraviolet-blocking compositions including metal oxide nanoparticles with nanocavities, as well as methods of enhancing ultraviolet absorbance efficiency of an ultraviolet blocking composition. Additional uses of metal oxide nanoparticles with nanocavities include solar energy conversion systems and lithium-ion batteries. | 05-07-2009 |
20090093863 | Method and Devices for Performing Stereotactic Microbeam Radiation Therapy - A radiation delivery system generally includes either a synchrotron source or a support frame and a plurality of microbeam delivery devices supported on the support frame, both to deliver a beam in a hemispherical arrangement. Each of the microbeam delivery devices or synchrotron irradiation ports is adapted to deliver at least one microbeam of radiation along a microbeam delivery axis, wherein the microbeam delivery axes of the plurality of microbeam delivery devices cross within a common target volume. | 04-09-2009 |
20090068505 | Electrocatalyst for Alcohol Oxidation at Fuel Cell Anodes - In some embodiments a ternary electrocatalyst is provided. The electrocatalyst can be used in an anode for oxidizing alcohol in a fuel cell. In some embodiments, the ternary electrocatalyst may include a noble metal particle having a surface decorated with clusters of SnO | 03-12-2009 |
20090057649 | Assembly of Ordered Carbon Shells on Semiconducting Nanomaterials - In some embodiments of the invention, encapsulated semiconducting nanomaterials are described. In certain embodiments the nanostructures described are semiconducting nanomaterials encapsulated with ordered carbon shells. In some aspects a method for producing encapsulated semiconducting nanomaterials is disclosed. In some embodiments applications of encapsulated semiconducting nanomaterials are described. | 03-05-2009 |
20090048510 | Fiducial Marker for Correlating Images - The invention relates to a fiducial marker having a marking grid that is used to correlate and view images produced by different imaging modalities or different imaging and viewing modalities. More specifically, the invention relates to the fiducial marking grid that has a grid pattern for producing either a viewing image and/or a first analytical image that can be overlaid with at least one other second analytical image in order to view a light path or to image different imaging modalities. Depending on the analysis, the grid pattern has a single layer of a certain thickness or at least two layers of certain thicknesses. In either case, the grid pattern is imageable by each imaging or viewing modality used in the analysis. Further, when viewing a light path, the light path of the analytical modality cannot be visualized by viewing modality (e.g., a light microscope objective). By correlating these images, the ability to analyze a thin sample that is, for example, biological in nature but yet contains trace metal ions is enhanced. Specifically, it is desired to analyze both the organic matter of the biological sample and the trace metal ions contained within the biological sample without adding or using extrinsic labels or stains. | 02-19-2009 |
20090026371 | High-Energy Detector - The preferred embodiments are directed to a high-energy detector that is electrically shielded using an anode, a cathode, and a conducting shield to substantially reduce or eliminate electrically unshielded area. The anode and the cathode are disposed at opposite ends of the detector and the conducting shield substantially surrounds at least a portion of the longitudinal surface of the detector. The conducting shield extends longitudinally to the anode end of the detector and substantially surrounds at least a portion of the detector. Signals read from one or more of the anode, cathode, and conducting shield can be used to determine the number of electrons that are liberated as a result of high-energy particles impinge on the detector. A correction technique can be implemented to correct for liberated electron that become trapped to improve the energy resolution of the high-energy detectors disclosed herein. | 01-29-2009 |
20080279781 | Glycosylated Carboranylporphyrins and Uses Thereof - The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity glycosylated carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, and head and neck. The invention is also directed to using these glycosylated carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET. | 11-13-2008 |
20080247512 | Sagittal Focusing Laue Monochromator - An x-ray focusing device generally includes a slide pivotable about a pivot point defined at a forward end thereof, a rail unit fixed with respect to the pivotable slide, a forward crystal for focusing x-rays disposed at the forward end of the pivotable slide and a rearward crystal for focusing x-rays movably coupled to the pivotable slide and the fixed rail unit at a distance rearward from the forward crystal. The forward and rearward crystals define reciprocal angles of incidence with respect to the pivot point, wherein pivoting of the slide about the pivot point changes the incidence angles of the forward and rearward crystals while simultaneously changing the distance between the forward and rearward crystals. | 10-09-2008 |
20080241907 | Extracellular Bioreduction - A method for processing environmental or industrial samples to remove, reclaim or otherwise reduce the level of chemical species present in the sample that act as redox active species. The redox active species is kept in a waste chamber and is separated from an aqueous bacterial culture that is held in a culture chamber. The waste chamber and the culture chamber are separated by a porous membrane through which electron transfer can occur but through which the aqueous bacterial culture cannot pass. The redox active species substantially remains in the waste chamber and is in non-contact with the aqueous bacterial culture during the process of removal, reduction or reclamation. | 10-02-2008 |
20080233047 | Symmetric and Asymmetric Halogen-Containing Metallocarboranylporphyrins and Uses Thereof - The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET. | 09-25-2008 |