BOEHRINGER INGELHEIM RCV GMBH & CO KG Patent applications |
Patent application number | Title | Published |
20140170702 | METHOD FOR PRODUCING A RECOMBINANT PROTEIN OF INTEREST - Disclosed is a method for producing a recombinant protein of interest, the method being characterised in by the following steps:
| 06-19-2014 |
20140170701 | METHOD FOR PRODUCING A RECOMBINANT PROTEIN OF INTEREST - Disclosed is a method for producing a recombinant protein of interest which is characterised by the following steps:
| 06-19-2014 |
20140154747 | METHODS AND DEVICES FOR PRODUCING BIOMOLECULES - A scalable process and device for producing a bio molecule, in particular pharmaceutical grade plasmid DNA is described. The process includes the steps of alkaline lysis, neutralization and clarification and can be further extended. For separating the lysate and the precipitate an improved floatation method is disclosed. This method is based on attachment of CO | 06-05-2014 |
20130059344 | TRANSCRIPTION TERMINATOR SEQUENCES - The present invention provides new transcription termination signal sequences, especially a polynucleotide comprising at least two consecutive transcription termination signals, characterized in that said consecutive transcription termination signals comprise at least a first and a second transcription termination signal that are at most 1000 nucleotides apart, and at least one of the termination signal has or encodes a RNA hairpin structure. | 03-07-2013 |
20120107869 | ORGANIC COMPOUNDS - Disclosed is a method for the production of a heterologous polypeptide of interest with a homogenous N-terminus, using a fusion polypeptide comprising the polypeptide of interest and N-terminally thereto a polypeptide exhibiting autoproteolytic function, said method comprising the steps of a) binding of the fusion polypeptide in a soluble, autoproteolytically inactive form by an affinity chromatography system, b) refolding of the fusion polypeptide, thereby activating the autoproteolytic function of the fusion polypeptide and causing cleavage of the heterologous polypeptide of interest, and c) subsequently eluting the heterologous polypeptide of interest, wherein said steps are conducted on one affinity chromatography system. | 05-03-2012 |
20110269184 | METHOD FOR CONTROLLING PLASMID COPY NUMBER IN E.COLI - Host vector system and methods for plasmid DNA and recombinant protein production. The system allows copy number control of a ColE1 plasmid in | 11-03-2011 |
20110124101 | METHODS AND DEVICES FOR PRODUCING BIOMOLECULES - A scalable process and device for producing a bio molecule, in particular pharmaceutical grade plasmid DNA is described. The process includes the steps of alkaline lysis, neutralization and clarification and can be further extended. For separating the lysate and the precipitate an improved floatation method is disclosed. This method is based on attachment of CO | 05-26-2011 |
20110045531 | METHOD FOR PRODUCING A RECOMBINANT PROTEIN ON A MANUFACTURING SCALE - A method for producing a protein of interest on a manufacturing scale is based on integration, by homologous recombination, of the DNA encoding the protein of interest into a bacterial cell genome at a pre-selected site. The manufacturing scale production of recombinant proteins is in the fed-batch mode, semi-continuous or in a chemostat. | 02-24-2011 |
20100151530 | METHOD FOR PRODUCING PLASMID DNA ON A MANUFACTURING SCALE - A method for producing plasmid DNA on a manufacturing scale uses | 06-17-2010 |