BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS Patent applications |
Patent application number | Title | Published |
20160058297 | DEVICE AND METHOD FOR IN VIVO FLOW CYTOMETRY USING THE DETECTION OF PHOTOACOUSTIC WAVES - A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents. | 03-03-2016 |
20150351640 | DEVICE AND METHOD FOR IN VIVO NONINVASIVE MAGNETIC MANIPULATION OF CIRCULATING OBJECTS IN BIOFLOWS - A device and methods for the non-invasive manipulation and detection of target objects such as cells, pathogens, microparticles, and nanoparticles in vivo using an external magnetic field are described. In one aspect, a device and method for capturing and detecting intrinsically magnetic target objects or target objects labeled with at least one magnetic particle within the area of interest using an in vivo flow cytometer are described. | 12-10-2015 |
20150338398 | METHODS AND KITS FOR ISOLATION AND ANALYSIS OF A CHROMATIN REGION - The present invention encompasses methods of identifying proteins and protein modifications of proteins specifically associated with a chromatin. | 11-26-2015 |
20150328216 | INDOLE COMPOUNDS FOR USE IN TREATING INFLAMMATION AND CANCER - Provided herein are compounds, comprising Formula (I) or Formula (II), and their pharmaceutically acceptable salts. Also provided are pharmaceutical compositions comprising a pharmaceutically acceptable excipient and at least one compound of Formula (I) and (II), singly or in combination with other pharmaceutically active ingredients, such as anti-inflammatory agents or anticancer agents. These compounds and pharmaceutical compositions are useful for treating inflammation or an inflammation related disorder in a subject via administration to the subject. These compounds and pharmaceutical compositions are also useful for inhibiting COX-2, for treating cancer, for reducing the size of a neoplasm, and for inhibiting tubulin polymerization in a cell. | 11-19-2015 |
20150282458 | FLOORING CHALLENGE SYSTEMS FOR CULLING POULTRY - Flooring challenge systems and processes for culling poultry reared in pens by adding torque, stress and strain on key leg joints in to induce lameness attributable to osteochondrosis and osteomyelitis of the proximal femur and tibia. The flooring challenge systems utilize one or more portable panels or sections that can be constructed in a wide range of sizes and configurations for installation in commercial poultry pens. In addition, the flooring challenge systems may utilize a device suspended a predetermined distance above the apex of the flooring challenge panel to subject the poultry's legs to asymmetric twisting and enhanced instability by forcing the birds to straddle opposing slopes near the apex of the flooring challenge panel. After a suitable incidence of lameness has been induced, the panels or sections of the flooring challenge system can be removed to facilitate cleanout of the rearing pens. | 10-08-2015 |
20150159131 | METHODS AND COMPOSITIONS FOR REGULATING MUSASHI FUNCTION - The invention generally features compositions and methods for detecting and regulating cell proliferation, potentiation, and differentiation in a population of cells. In particular, compositions and methods are provided for modulating the activity of Musashi proteins. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. | 06-11-2015 |
20150140016 | Molecular Determinants of Myeloma Bone Disease and Uses Thereof - The present invention is drawn to understanding lytic bone diseases. In this regard, the present invention discloses mechanism by which Wnt signaling antagonist inhibits bone differentiation. Also disclosed herein are methods for treating multiple myeloma, for restoring osteoprotegerin (OPG) expression in a cell, for inhibiting receptor activator of nuclear factor kappa B ligand (RANKL) expression in a cell, and for increasing bone mass in a subject. These methods utilize a DKK1 neutralizing antibody, an anti-sense oligonucleotide against a DKK1 gene, or a shRNA against a DKK1 gene to inhibit the activity of the DKK1 protein. | 05-21-2015 |
20150067910 | SOYBEAN CULTIVAR UA 5213C - A soybean cultivar designated UA 5213C is disclosed. The invention relates to the seeds of soybean cultivar UA 5213C, to the plants of soybean cultivar UA 5213C, to the plant parts of soybean cultivar UA 5213C, and to methods for producing progeny of soybean cultivar UA 5213C. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar UA 5213C. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar UA 5213C, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar UA 5213C with another soybean cultivar. | 03-05-2015 |
20140302995 | METHOD OF FORMING REWORKABLE, THERMALLY CONDUCTIVE AND ELECTRICALLY RESISTIVE BONDING STRUCTURE IN SUPERCONDUCTOR MULTI-CHIP MODULE USING REWORKABLE EPOXY BONDING COMPOSITES AND APPLICATION OF THE SAME - In one aspect, the present invention relates to a method of forming a reworkable, thermally conductive and electrically resistive material as a bonding structure in a module and application of the same. In certain embodiments, a homogeneous solution is prepared with an anisotropic structure, such as single-wall carbon nanotubes (SWCNTs), and an epoxy resin. The homogeneous solution is applied between a carrier and a chip of the module, and cured at a curing temperature for a curing time period to form a reworkable epoxy bonding layer, which has an anisotropic structure loading factor of about 0.1%-1.0% such that the reworkable epoxy bonding layer is thermally conductive and electrically resistive. When the chip is identified as a faulty chip, the module may be heated at a debonding temperature for a debonding time period such that the reworkable epoxy bonding layer debonds, and the chip becomes detachable from the carrier. | 10-09-2014 |
20140287508 | METHOD FOR APPLICATIONS OF NANO-SIZED MATERIALS AS CELL GROWTH REGULATORS / CELL GROWTH ENHANCERS FOR PLANT, AND AGENT INCLUDING NANO-SIZED MATERIALS - One aspect of the disclosure is directed to a method for activation/enhancement of cell growth of a plant. The method includes providing a nano-sized material contained agent, and treating the plant with the nano-sized material contained agent to allow sufficient interaction of cells of the plant with the nano-sized material so as to activate/enhance the cell growth of the plant. | 09-25-2014 |
20140262006 | BIODEGRADABLE POLYMERIC NANOCOMPOSITE MATERIALS AND APPLICATIONS OF THE SAME - A method for producing a polymer film includes: obtaining a load graph representing a functional relationship between a weight percentage of tissue forming nanoparticles in a polymer film and a maximum load of that polymer film; obtaining a stress graph representing a functional relationship between the weight percentage of tissue forming nanoparticles in a polymer film and maximum stress of that polymer film; determining a first weight percentage corresponding to a peak of the load graph and determining a second weight percentage corresponding to a peak of the stress graph; determining an optimal weight percentage based on the first and second weight percentage values; and producing a polymer film having tissue forming nanoparticles at the optimal weight percentage. | 09-18-2014 |
20140248319 | MULTICOMPONENT AND BIOCOMPATIBLE NANOCOMPOSITE MATERIALS, METHODS OF SYNTHESIZING SAME AND APPLICATIONS OF SAME - One aspect of the present invention relates to a method of synthesizing a multicomponent and biocompatible nanocomposite material, which includes: synthesizing a gold/hydroxyapatite (Au/HA) catalyst; distributing the Au/HA catalyst into a thin film; and heating the thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD) to form the nanocomposite material, where the nanocomposite material includes a graphene structure and Au/HA nanoparticles formed by the Au/HA catalyst and distributed within the graphene structure. In another aspect, a multicomponent and biocompatible nanocomposite material includes: a graphene structure formed with a plurality of graphene layers and Au/HA nanoparticles distributed within the graphene structure. The nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD). | 09-04-2014 |
20140238410 | Mouth Guard - A mouth guard including a top mouth piece for engaging the top teeth and a bottom mouth piece for engaging the bottom teeth. The mouth guard also includes a central section having one or more ports for receiving an endotracheal tube, oral gastric tube, and/or oral suction tube. In a first preferred embodiment, a top portion of the central section is attached to the top mouth piece, and a bottom portion of the central section is attached to the bottom mouth piece. In a second preferred embodiment, the entire central section is attached to the bottom mouth piece. The top and bottom mouth pieces are capable of interlocking via male engaging members and female recesses. | 08-28-2014 |
20140208451 | SOYBEAN CULTIVAR KK-09 - A soybean cultivar designated KK-09 is disclosed. The invention relates to the seeds of soybean cultivar KK-09, to the plants of soybean cultivar KK-09, to the plant parts of soybean cultivar KK-09, and to methods for producing progeny of soybean cultivar KK-09. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar KK-09. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar KK-09, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar KK-09 with another soybean cultivar. | 07-24-2014 |
20140179545 | Diagnosis, Prognosis and Identification of Potential Therapeutic Targets of Multiple Myeloma Based on Gene Expression Profiling - Gene expression profiling is a powerful tool that has varied utility. It enables classification of multiple myeloma into subtypes and identifying genes directly involved in disease pathogensis and clinical manifestation. The present invention used gene expression profiling in large uniformly treated population of patients with myeloma to identify genes associated with poor prognosis. It also demonstrated that over-expression of CKS1B gene, mainly due to gene amplification that was determined by Fluorescent in-situ hybridization to impart a poor prognosis in multiple myleoma. It is further contemplated that therapeutic strategies that directly target CKS1B or related pathways may represent novel, and more specific means of treating high risk myeloma and may prevent its secondary evolution. | 06-26-2014 |
20140173773 | SOYBEAN CULTIVAR KK-08 - A soybean cultivar designated KK-08 is disclosed. The invention relates to the seeds of soybean cultivar KK-08, to the plants of soybean cultivar KK-08, to the plant parts of soybean cultivar KK-08, and to methods for producing progeny of soybean cultivar KK-08. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar KK-08. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar KK-08, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar KK-08 with another soybean cultivar. | 06-19-2014 |
20140161890 | MULTIFUNCTIONAL Fe3O4 CORED MAGNETIC-QUANTUM DOT FLUORESCENT NANOCOMPOSITES FOR RF NANO-HYPERTHERMIA OF CANCER CELLS - A magnetic oxide-quantum dot nanocomposite has at least one magnetic oxide nanoparticle coated with a silica (SiO | 06-12-2014 |
20140159042 | TOP DOWN ALUMINUM INDUCED CRYSTALLIZATION FOR HIGH EFFICIENCY PHOTOVOLTAICS - Certain aspects of the present disclosure are directed to a method that includes: depositing, in a deposition environment, an amorphous semiconductor material on a substrate to form a semiconductor film on the substrate; filling, in the depositing process, the deposition environment with a first precursor material such that the semiconductor film formed on the substrate includes a first layer having a first material characteristic; filling, in the depositing process, the deposition environment with a crystallization-stop precursor material such that the silicon film includes a crystallization-stop layer having a crystallization characteristic different from a crystallization characteristic of the first layer; depositing a metal film on the semiconductor film; and annealing the semiconductor film and the metal film at an predetermined annealing temperature for a predetermined period of time such that the first layer is at least partially crystallized and the crystallization-stop layer is at least partially amorphous. | 06-12-2014 |
20140155365 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION - The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand. | 06-05-2014 |
20140154393 | CONJUGATED LINOLEIC ACID RICH VEGETABLE OIL PRODUCTION FROM LINOLEIC RICH OILS BY HETEROGENEOUS CATALYSIS - The invention is generally directed to conjugated linoleic acid (CLA)-rich vegetable oil production from linoleic rich oils by heterogeneous catalysis. A heterogeneous catalytic vacuum distillation process is used under high temperature conditions to isomerize linoleic acid in triacylglyceride vegetable oils to CLA to produce CLA-rich oils. After processing, the catalyst may be removed by filtration or centrifugation to obtain high quality, CLA-rich oils. The CLA-rich oils may then serve as a potent and bioactive nutraceutical and can be incorporated into various food products, such as a CLA-rich dressing, margarine or chips. | 06-05-2014 |
20140154372 | FROZEN DESSERT COMPOSITIONS AND METHODS OF PREPARATION THEREOF - The invention relates to frozen dessert compositions and methods of preparation thereof. In particular, the invention is relates to a method for preparing a frozen dessert composition, such as ice cream, fortified with vegetables and/or fruits and soybeans, such as edamame or dried mature soybeans and the resulting enriched frozen dessert compositions having a fine texture, good and creamy mouth-feel and tastes with different flavors. | 06-05-2014 |
20140102988 | USE OF MAGNETIC CARBON COMPOSITES FROM RENEWABLE RESOURCE MATERIALS FOR OIL SPILL CLEAN UP AND RECOVERY - A method of separating a liquid hydrocarbon material from a body of water, includes: (a) mixing magnetic carbon-metal nanocomposites with a liquid hydrocarbon material dispersed in a body of water to allow the magnetic carbon-metal nanocomposites each to be adhered by the liquid hydrocarbon material to form a mixture; (b) applying a magnetic force to the mixture to attract the magnetic carbon-metal nanocomposites each adhered by the liquid hydrocarbon material; and (c) removing the body of water from the magnetic carbon-metal nanocomposites each adhered by the liquid hydrocarbon material while maintaining the applied magnetic force. The magnetic carbon-metal nanocomposites is formed by subjecting one or more metal lignosulfonates or metal salts to microwave radiation, in presence of lignin/derivatives either in presence of alkali or a microwave absorbing material, for a period of time effective to allow the carbon-metal nanocomposites to be formed. | 04-17-2014 |
20140082767 | METHOD FOR PRODUCING STRESS TOLERANT TRANSGENIC PLANT BY SILENCING A GENE ENCODING CALCIUM-DEPENDENT LIPID-BINDING PROTEIN WITH C2 DOMAIN AND APPLICATIONS OF THE SAME - A transgenic plant includes a first gene having a first polynucleotide and a recombinant construct having a second polynucleotide. The first polynucleotide is homologous to a Atclb gene fragment represented by nucleotide acids 963-1205 of SEQ ID NO:1. The first polynucleotide encodes a C2-like domain, and the Atclb gene fragment encodes a C2 domain represented by amino acids 265-345 of SEQ ID NO:2. The C2-like domain is homologous to the C2 domain. The second polynucleotide has at least 90% identity to the first polynucleotide or a sequence complimentary to the first polynucleotide. The recombinant construct is configured to silence the first gene such that the transgenic plant is tolerant to abiotic stress. A method to produce the transgenic plants. | 03-20-2014 |
20140073762 | MULTIPLE STATIONARY PHASE MATRIX AND USES THEREOF - The present invention generally provides a separation matrix comprising at least two stationary phases and a stationary phase comprising at least one chiral modality and at least one achiral modality. Also provided are methods of using the separation matrix or the stationary phase to separate enantiomers of one or more chiral molecules. | 03-13-2014 |
20140026250 | SOYBEAN CULTIVAR UA KIRKSEY - A soybean cultivar designated UA Kirksey is disclosed. The invention relates to the seeds of soybean cultivar UA Kirksey, to the plants of soybean cultivar UA Kirksey, to the plant parts of soybean cultivar UA Kirksey, and to methods for producing progeny of soybean cultivar UA Kirksey. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar UA Kirksey. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar UA Kirksey, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar UA Kirksey with another soybean cultivar. | 01-23-2014 |
20140024565 | Nanoparticle Compositions and Methods for Making and Using the Same - A composition that includes solid lubricant nanoparticles and an organic medium is disclosed. Also disclosed are nanoparticles that include layered materials. A method of producing a nanoparticle by milling layered materials is provided. Also disclosed is a method of making a lubricant, the method including milling layered materials to form nanoparticles and incorporating the nanoparticles into a base to form a lubricant. | 01-23-2014 |
20130345080 | Diagnosis, Prognosis and Identification of Potential Therapeutic Targets of Multiple Myeloma Based on Gene Expression Profiling - Gene expression profiling is a powerful tool that has varied utility. It enables classification of multiple myeloma into subtypes and identifying genes directly involved in disease pathogensis and clinical manifestation. The present invention used gene expression profiling in large uniformly treated population of patients with myeloma to identify genes associated with poor prognosis. It also demonstrated that over-expression of CKS1B gene, mainly due to gene amplification that was determined by Fluorescent in-situ hybridization to impart a poor prognosis in multiple myeloma. It is further contemplated that therapeutic strategies that directly target CKS1B or related pathways may represent novel, and more specific means of treating high risk myeloma and may prevent its secondary evolution. | 12-26-2013 |
20130338025 | USE OF GENE EXPRESSION PROFILING TO PREDICT SURVIVAL IN CANCER PATIENT - Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to over-expression of genes such as ASPM, OPN3 and CKS1B which are located in chromosome 1q. Given the frequent amplification of 1q in many cancers, it is possible that these genes can be used as powerful prognostic markers and therapeutic targets for multiple myeloma and other cancer. | 12-19-2013 |
20130310710 | Pneumatic Tocodynamometer - A pneumatic tocodynamometer (“pTOCO”) ( | 11-21-2013 |
20130304229 | BONE REGENERATION USING BIODEGRADABLE POLYMERIC NANOCOMPOSITE MATERIALS AND APPLICATIONS OF THE SAME - A structure of, and a method of producing, a biocompatible structure for bone and tissue regeneration are disclosed. The method includes dissolving a polyurethane polymer in methanol, adding hydroxyapatite (HAP) nanoparticles to form a uniformly distributed mixture, applying the mixture to a polytetrafluoroethylene (PTFE) surface to form a polymer film, cutting the polymer film into strips, stacking the strips with layers of bone particles disposed therebetween, coating the stacked strips and layers by the mixture and allowing it to dry, adding bone particles to the coating, and plasma treating the structure to form the biocompatible structure. A weight percentage of the HAP nanoparticles to the polymer is about 5-50% such that a resorption rate of the biocompatible structure substantially matches a rate of tissue generation in the biocompatible structure. | 11-14-2013 |
20130295714 | SYSTEMS AND METHODS FOR SITE CONTROLLED CRYSTALLIZATION - Systems and methods for site controlled crystallization are disclosed. According to one aspect, a method for forming a composite film is disclosed. In one example embodiment, the method includes forming a layer of amorphous material. The method also includes forming a layer of metal material on each of a plurality of selected regions of the layer of amorphous material to form a structure including the layer of metal material on the layer of amorphous material, and annealing the structure to generate metal-induced crystallization at the interface of the layer of metal material and each of the selected regions of the layer of amorphous material such that crystalline structures are formed. | 11-07-2013 |
20130269762 | CORE-SHELL NANOSTRUCTURE BASED PHOTOVOLTAIC CELLS AND METHODS OF MAKING SAME - A photovoltaic cell includes nanostructures formed of nanowires on a substrate, where the nanostructures include an array of three dimensional nanotrees or nanobushes with a core-shell structure having a core and one or more shells sequentially formed on the core. The core o f the core-shell structure is formed of a highly conductive metal or semiconductor, and the shell o f the core-shell structure is formed of a metal, semiconductor, or polymer, such that the core-shell structure has substantially large surface and interface area for photon energy harvesting and conversion into electricity. | 10-17-2013 |
20130255339 | PROCESS FOR REDUCING WATER SOLUBLE ELEMENTS USING AN AMENDED ANIMAL MANURE FERTILIZER OR LITTER - The invention relates to process for reducing water soluble elements, namely phosphorus, in animal manure fertilizer and/or litter, namely poultry litter, using chitin or chitosan. The amended fertilizer or litter has useful applications in confined animal production for reducing the water solubility of phosphorous and other trace elements in manure and litter. | 10-03-2013 |
20130233802 | RENEWABLE RESOURCE-BASED METAL OXIDE-CONTAINING MATERIALS AND APPLICATIONS OF THE SAME - Metal nanocomposites and methods of producing the same are disclosed. The nanocomposites have metal nanoparticles dispersed in a matrix carrier and can be produced by: treating a matrix material having a functional group with a quaternary amine compound to form a function site; treating the matrix material with a metal salt such that a metal ion of the metal salt is chelated with the functional site; treating the matrix material with an alkali; and microwaving the matrix material to form the metal nanocomposites. | 09-12-2013 |
20130229889 | System and Method for Dissolving Gases in Fluids and for Delivery of Dissolved Gases - Apparatus and methods are disclosed for facilitating dissolution of one or more gases into a liquid. Preferred gases for use with the apparatus are oxygen, air, and ozone. An apparatus of the present invention comprises a dissolution tank that includes a pressure vessel, at least one liquid spray nozzle, and a fluid outlet. The apparatus also comprises a gas source, means for passing fluid into the pressure vessel, and a discharge device connected to the fluid outlet, which discharge device is provided with at least one orifice. Preferred applications include wastewater treatment, treatment of drinking water, fermentation, and bioremediation. | 09-05-2013 |
20130209446 | Copy Number Variant-Dependent Genes As Diagnostic Tools, Predictive Biomarkers And Therapeutic Targets - Provided herein are methods of diagnosing and/or treating malignant or pre-malignant conditions in a subject. Overexpression of copy number variant-dependent genes, e.g., genes encoding a cell surface receptor, resulting from copy number changes compared to control is diagnostic of the condition, such as multiple myeloma or monoclonal gammopathy of undetermined significance. Also provided are methods for treating malignant conditions, such as multiple myeloma or a hyperdiploid subtype, with therapeutic agents, with or without other anti-cancer drugs, to downrregulate the overexpressed CNV genes and/or up-regulate the underexpressed genes. Furthermore, methods for lowering drug resistance in multiple myeloma cells via inhibition of platelet activation or thrombin release and for increasing survivability of a multiple myeloma subject via lithibition of PSMD4 gene to increase b-catenin protein expression are provided. | 08-15-2013 |
20130200386 | CRYSTALLIZATION OF MULTI-LAYERED AMORPHOUS FILMS - In one aspect, crystallization of multiple layers of amorphous materials is disclosed. In one embodiment, multiple layers of amorphous materials such as amorphous silicon, silicon carbide, and/or germanium are deposited using deposition methods such as PECVD or sputtering. A layer of metal such as aluminum is deposited on the surface of the deposited amorphous materials using sputtering or evaporation, and the structure is annealed in a hydrogen environment. The structure is contained on a semiconductor substrate, glass, a flexible metal/organic film, or other type of substrate. | 08-08-2013 |
20130157838 | DOPED-CARBON COMPOSITES, SYNTHESIZING METHODS AND APPLICATIONS OF THE SAME - A method of synthesizing a doped carbon composite includes preparing a solution having a carbon source material and a heteroatom containing additive, evaporating the solution to yield a plurality of powders, and subjecting the plurality of powders to a heat treatment for a duration of time effective to produce the doped carbon composite. | 06-20-2013 |
20130136696 | METALLIC NANOPARTICLES WITH COATED SHELLS AND APPLICATIONS OF SAME - A process or method for treating cancer. In one embodiment, the method includes the steps of providing a plurality of metallic nanoparticles, wherein each of the plurality of metallic nanoparticles has a core formed with a first metallic material, and a shell formed with a non-metallic material containing carbon, and wherein the shell is formed to enclose the metallic core completely, introducing said metallic nanoparticles into a mammal such that said metallic nanoparticles selectively target at least one type of cancerous cell, and subsequently applying at least one radio frequency of electromagnetic waves to said mammal for a period of time effective to induce skin currents in the cores of the first metallic material of said metallic nanoparticles to cause heat generated locally around targeted at least one type of cancerous cell to kill said cancerous cell. | 05-30-2013 |
20130104665 | STRAIN SENSORS, METHODS OF MAKING SAME, AND APPLICATIONS OF SAME | 05-02-2013 |
20130093852 | PORTABLE ROBOTIC DEVICE - A portable robotic device (PRD) as well as related devices and methods are described herein. The PRD includes a 3-D imaging sensor configured to acquire corresponding intensity data frames and range data frames of the environment. An imaging processing module configured to identify a matched feature in the intensity data frames, obtain sets of 3-D coordinates representing the matched feature in the range data frames, and determine a pose change of the PRD based on the 3-D coordinates; and perform 3-D data segmentation of the range data frames to extract planar surfaces. | 04-18-2013 |
20130072392 | Compositions, Kits, and Methods for Identification, Assessment, Prevention, and Therapy of Cancer - The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human cancer. A variety of chromosomal regions (MCRs) and markers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the MCRs and/or alterations in the amount, structure, and/or activity of one or more of the markers is correlated with the presence of cancer. | 03-21-2013 |
20130064863 | MULTICOMPONENT AND BIOCOMPATIBLE NANOCOMPOSITE MATERIALS, METHODS OF SYNTHESIZING SAME AND APPLICATIONS OF SAME - One aspect of the present invention relates to a method of synthesizing a multicomponent and biocompatible nanocomposite material, which includes: synthesizing a gold/hydroxyapatite (Au/HA) catalyst; distributing the Au/HA catalyst into a thin film; and heating the thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD) to form the nanocomposite material, where the nanocomposite material includes a graphene structure and Au/HA nanoparticles formed by the Au/HA catalyst and distributed within the graphene structure. In another aspect, a multicomponent and biocompatible nanocomposite material includes: a graphene structure formed with a plurality of graphene layers and Au/HA nanoparticles distributed within the graphene structure. The nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD). | 03-14-2013 |
20130060122 | DEVICE AND METHOD FOR IN VIVO FLOW CYTOMETRY USING THE DETECTION OF PHOTOACOUSTIC WAVES - A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents. | 03-07-2013 |
20130044919 | SYSTEM AND METHOD OF IN-SEASON NITROGEN MEASUREMENT AND FERTILIZATION OF NON-LEGUMINOUS CROPS FROM DIGITAL IMAGE ANALYSIS - Systems and methods of determining nitrogen levels from a digital image and in-season nitrogen measurement and fertilization of non-leguminous crops from digital image analysis are disclosed herein. In particular, a method of determining leaf nitrogen concentration and yield from a digital photograph of a fully developed leaf (collared leaf) of a crop of non-legumes, such as corn, wheat, rice, cotton, potatoes sugarcane, turfgrass or forage grass species. The digital image is processed to determine a dark green color index (“DGCI”), which is closely related to leaf nitrogen concentration and yield. Standardized color disks having known DGCI values are included in the digital photograph and serve as an comparative standard. The comparative standard allows correction of DGCI of samples when using different cameras and/or when lighting conditions change. The DGCI values can then be used to determine the amount of nitrogen fertilizer that should be applied to recover crop yield potential. | 02-21-2013 |
20130029367 | COMPOSITIONS AND METHODS FOR MONITORING BREAST CANCER TREATMENT - The present invention provides compositions and processes for preparing the same wherein the compositions are useful for monitoring breast cancer treatment. | 01-31-2013 |
20130011404 | Methods and Compositions for Regulating Musashi Function - The invention generally features compositions and methods for detecting and regulating cell proliferation, potentiation, and differentiation in a population of cells. In particular, compositions and methods are provided for modulating the activity of Musashi proteins. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. | 01-10-2013 |
20120325162 | FLOORING CHALLENGE SYSTEMS FOR CULLING POULTRY - Flooring challenge systems for culling poultry that induce lameness attributable to osteochondrosis and osteomyelitis of the proximal femur and tibia in poultry. The flooring challenge systems induce unstable or insecure footing for poultry reared in pens by adding torque, stress and strain on key leg joints in order to exacerbate and accelerate the development of bacterial chondronecrosis with osteomyelitis lesions and lameness. The flooring challenge systems utilize one or more portable panels or sections that can be constructed in a wide range of sizes and configurations for installation in commercial poultry pens. In addition, the flooring challenge systems may utilize a device suspended a predetermined distance above the apex of the flooring challenge panel to subject the poultry's legs to asymmetric twisting and enhanced instability by forcing the birds to straddle opposing slopes near the apex of the flooring challenge panel. | 12-27-2012 |
20120301897 | ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD - The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample. | 11-29-2012 |
20120295974 | TRANS-, TRANS-CONJUGATED LINOLEIC ACID COMPOSITIONS AND USE THEREOF - This invention relates generally to trans-,trans-conjugated linoleic acid compositions and use thereof, and in particular to trans-,trans-conjugated linoleic acid produced from photoisomerization of soy oil in the presence of an antioxidant, and used in pharmaceutical, nutraceutical and human and animal food compositions for improved health. The invention also relates generally to a method for treatment and prevention of health-related disorders of obesity by administration of pharmaceutical, nutraceutical and/or food compositions containing and/or prepared from trans-,trans-conjugated linoleic acid-rich soy oil. | 11-22-2012 |
20120270311 | FEMALE SPECIFIC INSECT EXPRESSION SYSTEM - The present invention provides an insect expression system that may be used to provide biological control of pest insects and control transmission of infectious diseases transmitted to the human population by insects. | 10-25-2012 |
20120264123 | Extracellular Serine Protease - The present invention provides a DNA encoding a novel extracellular serine protease termed Tumor Antigen Derived Gene-14 (TADG-14) which is overexpressed in ovarian, breast and colon carcinoma samples. Also provided are vector and host cells capable of expressing the DNA of the present invention, as well as the uses of the DNA and protein of the present invention. Also provided is a TADG-14 protein variant that has a potential role for detecting and targeting of ovarian carcinomas. | 10-18-2012 |
20120244224 | NANOSTRUCTURAL MATERIALS THAT INCREASE MINERALIZATION IN BONE CELLS AND AFFECT GENE EXPRESSION THROUGH miRNA REGULATION AND APPLICATIONS OF SAME - A method of inducing mineralization in a bone cell is described. The method comprises contacting a bone cell with a composition comprising nanoparticles. The nanoparticles can be single-walled carbon nanotubes, hydroxyapatite nanoparticles, TiO | 09-27-2012 |
20120226054 | MULTIPLE STATIONARY PHASE MATRIX AND USES THEREOF - The present invention generally provides a separation matrix comprising at least two stationary phases and a stationary phase comprising at least one chiral modality and at least one achiral modality. Also provided are methods of using the separation matrix or the stationary phase to separate enantiomers of one or more chiral molecules. | 09-06-2012 |
20120121821 | RENEWABLE RESOURCE-BASED METAL-CONTAINING MATERIALS AND APPLICATIONS OF THE SAME - In accordance with certain aspects of the present disclosure, a method of producing carbon-metal nanocomposites includes (a) treating a material containing at least one o-catechol unit with a first solution of hexamine such that the material becomes hexamine treated; (b) treating the material with a second solution having a plurality of metal ions such that the material becomes metal treated; (c) treating the material with a third solution of alkali such that the material becomes alkali treated; and (d) heating the alkali, metal and hexamine treated material after (a), (b), and (c) for a predetermined period of time such that a plurality of carbon-metal nanocomposites having metal nanoparticles dispersed in the material are produced. | 05-17-2012 |
20120065490 | DEVICE AND METHOD FOR IN VIVO DETECTION OF CLOTS WITHIN CIRCULATORY VESSELS - A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described. | 03-15-2012 |
20110304934 | BROADBAND OPTICAL LIMITER BASED ON NANO-GRAPHENE AND METHOD OF FABRICATING SAME - The present invention in one aspect relates to a low-cost, nano-graphene based broadband optical limiter with limiting properties superior to current standards, carbon fullerenes (C | 12-15-2011 |
20110301232 | PROCESS OF EXTRACTING PROCYANIDINS BY ALKALINE HYDROLYSIS - A process of extracting procyanidins by alkaline hydrolysis. In particular, a procyanidin-containing material, pomace or residue is treated with an alkali, such as sodium or potassium hydroxide, for a predetermined amount of time and at a predetermined temperature to release procyanidins bound to polysaccharides and/or proteins of the cell wall or depolymerize polymeric procyanidins. After the procyanidins are released by alkaline hydrolysis, the extracts are acidified to obtain a pH level where the procyanidins do not degrade. The process of extracting procyanidins may be utilized to estimate the total amount of bound procyanidins in a plant material, enhance the bioavailability of beneficial procyanidins monomers and/or to treat the residue remaining after conventional solvent extraction for increased procyanidin extraction. | 12-08-2011 |
20110291049 | INDIUM ARSENIDE NANOCRYSTALS AND METHODS OF MAKING THE SAME - The present invention provides high quality monodisperse or substantially monodisperse InAs nanocrystals in the as-prepared state. In some embodiments, the as-prepared substantially monodisperse InAs nanocrystals demonstrate a photoluminescence of between about 700 nm and 1400 nm. | 12-01-2011 |
20110286636 | System and method of determining nitrogen levels from a digital image - A system and method of determining nitrogen levels from a digital image. In particular, a method of determining leaf nitrogen concentration and yield from a digital photograph of a fully developed leaf (collared leaf) of a crop of nonlegumes, such as corn, rice, wheat, cotton, potatoes or sugarcane. The digital image is processed to determine a dark green color index (“DGCI”), which is closely related to leaf nitrogen concentration and yield. Standardized color disks having known DGCI values are included in the digital photograph and serve as an internal standard. The internal standard allows correction of DGCI of samples when using different cameras and/or when lighting conditions change. | 11-24-2011 |
20110285992 | METHODS OF FABRICATING SURFACE ENHANCED RAMAN SCATTERING SUBSTRATES - A method of fabricating a surface enhanced Raman scattering (SERS) substrate. In one embodiment, the method has the steps of simultaneously evaporating a metal at a first evaporation rate and a polymer at a second evaporation rate different from the first evaporation rate, to form a nanocomposite of the metal and the polymer, depositing the nanocomposite onto a substrate, and applying an etching process to the deposited nanocomposite on the substrate to remove the polymer material, thereby forming an SERS substrate. | 11-24-2011 |
20110237862 | MULTIFUNCTIONAL Fe3O4 CORED MAGNETIC-QUANTUM DOT FLUORESCENT NANOCOMPOSITES FOR RF NANO-HYPERTHERMIA OF CANCER CELLS - A magnetic oxide-quantum dot nanocomposite and methods of synthesizing it. In one embodiment, the magnetic oxide-quantum dot nanocomposite has at least one magnetic oxide nanoparticle coated with a silica (SiO | 09-29-2011 |
20110236495 | ANTI-CANCER NANOPARTICLE COMPOSITIONS AND METHODS OF USE - The present invention encompasses a composition capable of delivering and expressing a nucleic acid encoding UDP-Glucuronosyltransferases, p53 or a combination thereof into a cell, and methods for treating tumors. | 09-29-2011 |
20110236435 | ENHANCED BONE CELLS GROWTH AND PROLIFERATION ON TiO2 NANOTUBULAR SUBSTRATES TREATED BY RADIO-FREQUENCY PLASMA DISCHARGE - A method for growing bone cells. In one aspect, the present invention provides a method for growing bone cells, comprising the steps of (a) anodizing a titanium substrate to form an array of titanium dioxide nanotubes on a surface of the titanium substrate, (b) subjecting the anodized titanium substrate to a radio frequency plasma discharge to chemically modify the array of titanium dioxide nanotubes formed on the surface of the titanium substrate, (c) seeding bone cells onto the surface of the titanium substrate that has an array of titanium dioxide nanotubes thereon after the subjecting step, and (d) incubating the seeded bone cells for a period of time effective for the cells to grow and proliferate. | 09-29-2011 |
20110225662 | FEMALE SPECIFIC INSECT EXPRESSION SYSTEM - The present invention provides an insect expression system that may be used to provide biological control of pest insects and control transmission of infectious diseases transmitted to the human population by insects. | 09-15-2011 |
20110213018 | COMPOSITIONS AND METHODS FOR REGULATION OF SMOOTH MUSCLE CELLS AND BLOOD PRESSURE - The invention encompasses a composition for regulating smooth muscle cells. In particular, the invention encompasses a vector comprising a smooth muscle promoter operably-linked to a nucleic acid encoding a calcium-activated potassium channel. | 09-01-2011 |
20110200561 | Method for Bacteriophage Delivery and Amplification - Disclosed are methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods. Also disclosed are methods of treating a subject infected with a pathogenic bacterium using bacteriophage and methods of decontaminating objects using bacteriophage. Also disclosed are methods of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are disclosed. | 08-18-2011 |
20110198569 | APPARATUS AND METHODS OF NANOPATTERNING AND APPLICATIONS OF SAME - A method for patterning nanostructures in a semiconductor heterostructure, which has at least a first layer and a second layer, wherein the first layer has a first surface and an opposite, second surface, the second layer has a first surface and an opposite, second surface, and the first layer is deposited over the second layer such that the second surface of the first layer is proximate to the first surface of the second layer. The method includes the steps of making indentations in a pattern on the first surface of the first layer of the semiconductor heterostructure; bonding the semiconductor heterostructure to a support substrate such that the first surface of the first layer of the semiconductor heterostructure is faced to the support substrate; etching off the second layer of the semiconductor heterostructure; and depositing a third layer over the second surface of the first layer of the semiconductor heterostructure. | 08-18-2011 |
20110189841 | FABRICATION OF LARGE GRAIN POLYCRYSTALLINE SILICON FILM BY NANO ALUMINUM-INDUCED CRYSTALLIZATION OF AMORPHOUS SILICON - One aspect of the present invention relates to a method for fabricating a polycrystalline silicon film. In one embodiment, the method includes the steps of providing a substrate having a thermally-grown silicon dioxide layer, forming an amorphous silicon film on the thermally-grown silicon dioxide layer of the substrate, forming an aluminum layer on the amorphous silicon film to form a structure having the substrate, the amorphous silicon film and the aluminum layer, and annealing the structure at an annealing temperature for a period of time in an N | 08-04-2011 |
20110174738 | METHODS OF SYNTHESIZING CARBON-MAGNETITE NANOCOMPOSITES FROM RENEWABLE RESOURCE MATERIALS AND APPLICATION OF SAME - A method of synthesizing carbon-magnetite nanocomposites. In one embodiment, the method includes the steps of (a) dissolving a first amount of an alkali salt of lignosulfonate in water to form a first solution, (b) heating the first solution to a first temperature, (c) adding a second amount of iron sulfate (FeSO | 07-21-2011 |
20110171110 | MICROWAVE-ASSISTED SYNTHESIS OF CARBON NANOTUBES FROM TANNIN, LIGNIN, AND DERIVATIVES - A method of synthesizing carbon nanotubes. In one embodiment, the method includes the steps of: (a) dissolving a first amount of a first transition-metal salt and a second amount of a second transition-metal salt in water to form a solution; (b) adding a third amount of tannin to the solution to form a mixture; (c) heating the mixture to a first temperature for a first duration of time to form a sample; and (d) subjecting the sample to a microwave radiation for a second duration of time effective to produce a plurality of carbon nanotubes. | 07-14-2011 |
20110171108 | MICROWAVE-ASSISTED SYNTHESIS OF NANODIAMONDS FROM TANNIN, LIGNIN, ASPHALT, AND DERIVATIVES - A method of synthesizing nanodiamonds. In one embodiment, the present invention provides a method of synthesizing nanodiamonds, which includes the step of subjecting an amount of tannin to a microwave radiation for a duration of time effective to produce a plurality of nanodiamonds. | 07-14-2011 |
20110170208 | BROADBAND OPTICAL LIMITER BASED ON NANO-GRAPHENE AND METHOD OF FABRICATING SAME - The present invention in one aspect relates to a low-cost, nano-graphene based broadband optical limiter with limiting properties superior to current standards, carbon fullerenes (C | 07-14-2011 |
20110165555 | Capillary-Column-Based Bioseparator/Bioreactor with an Optical/Electrochemical Detector for Detection of Microbial Pathogens - The present invention is directed to satisfying the need to detect microbial contamination of food products. The described bioseparator/bioreactor coupled with an optical/electrochemical biosensor was able to specifically detect | 07-07-2011 |
20110152180 | BIOACTIVE PENTAPEPTIDES FROM RICE BRAN AND USE THEREOF - In general, the invention relates to novel bioactive pentapeptides from heat stabilized defatted rice bran having anti-cancer, anti-obesity, anti-Alzheimer and other health-promoting activities proteins. The bioactive pentapeptides can be incorporated into pharmaceutical, nutraceuticals and food compositions having at least the bioactive pentapeptide as an active ingredient. | 06-23-2011 |
20110132380 | Mouth guard - A mouth guard comprising a top mouth piece for engaging the top teeth and a bottom mouth piece for engaging the bottom teeth. The mouth guard also comprises a central section having one or more ports for receiving an endotracheal tube, oral gastric tube, and/or oral suction tube. In a first preferred embodiment, a top portion of the central section is attached to the top mouth piece, and a bottom portion of the central section is attached to the bottom mouth piece. In a second preferred embodiment, the entire central section is attached to the bottom mouth piece. The top and bottom mouth pieces are capable of interlocking via male engaging members and female recesses. | 06-09-2011 |
20110117028 | DEVICE AND METHOD FOR IN VIVO NONINVASIVE MAGNETIC MANIPULATION OF CIRCULATING OBJECTS IN BIOFLOWS - A device and methods for the non-invasive manipulation and detection of target objects such as cells, pathogens, microparticles, and nanoparticles in vivo using an external magnetic field are described. In one aspect, a device and method for capturing and detecting intrinsically magnetic target objects or target objects labeled with at least one magnetic particle within the area of interest using an in vivo flow cytometer are described. | 05-19-2011 |
20110091919 | pH-INSENSITIVE GLUCOSE INDICATOR PROTEIN - The present invention encompasses a glucose indicator protein, a biosensor comprising one or more glucose indicator proteins, and methods of use thereof. | 04-21-2011 |
20110086030 | INHIBITION OF CANCER METASTASIS - The present invention provides methods for inhibiting tumor cell metastasis. In particular, the invention provides methods for reducing tumor cell malignancy by administering to a subject an antibody that inhibits glycoprotein Ibα, such that tumor cell malignancy is reduced. | 04-14-2011 |
20110046081 | CLASSICAL CANNABINOID METABOLITES AND METHODS OF USE THEREOF - The present invention encompasses classical cannabinoid metabolites and uses thereof. | 02-24-2011 |
20110025571 | Circularly Polarized Microstrip Antennas - The present invention in one aspect relates to a circularly polarized antenna having a conductive ground layer, a conductive patch and a dielectric substrate formed between the conductive ground layer and the conductive patch. The conductive patch formed in a square shape with four equal sides and has four square slots with each formed in the central portion of each side, and two rectangular slots orthogonally formed in the central area of the square such that one rectangular slot is aligned with one diagonal of the square, the other rectangular slot is aligned with the other diagonal of the square, and the junction of the two rectangular slots is coincident with the geometrical center of the square. | 02-03-2011 |
20110024792 | Photovoltaic Device Using Single Wall Carbon Nanotubes and Method of Fabricating the Same - A photovoltaic device and methods for forming the same. In one embodiment, the photovoltaic device has a silicon substrate, and a film comprising a plurality of single wall carbon nanotubes disposed on the silicon substrate, wherein the plurality of single wall carbon nanotubes forms a plurality of heterojunctions with the silicon in the substrate. | 02-03-2011 |
20110024697 | Methods of Producing Carbon Nanotubes and Applications of Same - The present invention in one aspect relates to a method for producing carbon nanotubes. In one embodiment, the method includes the steps of forming a substrate, depositing a loading amount of catalyst including iron and cobalt nanoparticles on the surfaces of the substrate, and heating the catalyst deposited on the substrate in a radio frequency reactor having a flow of a methane carbon source at a predetermined temperature so as to cause the growth of carbon nanotubes on the substrate. | 02-03-2011 |
20100328647 | CARBON NANOTUBE-HYDROGEN PEROXIDE HYBRID BASED OPTICAL SENSING METHOD FOR ASSESSMENT OF ANTIOXIDANT POTENCY - An ultrasensitive dual optical method for measuring antioxidant concentration and total antioxidant capacity is provided. Using the process, the detection limit for vitamin C is as low as 7 nM. The method is based on a hybrid of single walled carbon nanotubes (SWNT) with hydrogen-peroxide. The method provides is a robust, cheap, fast, and reusable optical sensing method for antioxidant and total antioxidant capacity measurement in foods and plasma. The method can also be developed as a miniature assay for both in vitro and in vivo detection. | 12-30-2010 |
20100310442 | MICROWAVE-ASSISTED SYNTHESIS OF TRANSITION METAL PHOSPHIDE - A method of synthesizing transition metal phosphide. In one embodiment, the method has the steps of preparing a transition metal lignosulfonate, mixing the transition metal lignosulfonate with phosphoric acid to form a mixture, and subjecting the mixture to a microwave radiation for a duration of time effective to obtain a transition metal phosphide. | 12-09-2010 |
20100307983 | USE OF MAGNETIC CARBON COMPOSITES FROM RENEWABLE RESOURCE MATERIALS FOR OIL SPILL CLEAN UP AND RECOVERY - A method for separating a liquid hydrocarbon material from a body of water. In one embodiment, the method includes the steps of mixing a plurality of magnetic carbon-metal nanocomposites with a liquid hydrocarbon material dispersed in a body of water to allow the plurality of magnetic carbon-metal nanocomposites each to be adhered by an amount of the liquid hydrocarbon material to form a mixture, applying a magnetic force to the mixture to attract the plurality of magnetic carbon-metal nanocomposites each adhered by an amount of the liquid hydrocarbon material, and removing said plurality of magnetic carbon-metal nanocomposites each adhered by an amount of the liquid hydrocarbon material from said body of water while maintaining the applied magnetic force, wherein the plurality of magnetic carbon-metal nanocomposites is formed by subjecting one or more metal lignosulfonates or metal salts to microwave radiation, in presence of lignin/derivatives either in presence of alkali or a microwave absorbing material. | 12-09-2010 |
20100285138 | COMPOSITIONS COMPRISING NANOPARTICLES AND APOPTOTIC AGENTS AND METHODS OF USE - Compositions comprising nanoparticles, such as silver or gold nanoparticles or carbon nanotubes (CNTs), and apoptotic agents are described. The nanoparticles can significantly enhance the cancer chemotherapeutic effects of the apoptotic agents. In particular, a highly increased anti-tumor activity has been demonstrated for the combination of etoposide and CNTs against HeLa cells compared to the administration of either etoposide alone or nanoparticles alone. Data provided by flow cytometry, Caspase 3 and other methods, suggest a strong interaction between the nanoparticles and the cellular structure, which can result in the improved effectiveness of chemotherapeutic agents. These findings provide potential new cancer therapies by carefully selecting the right combination of cytostatic drugs and nanostructural materials which synergistically provide significantly greater curative rates. | 11-11-2010 |
20100279084 | Superhydrophobic Surface and Method of Forming Same - A superhydrophobic surface and method for forming same. In one embodiment, the method has the steps of preparing a surface of a substrate of a first material, modifying the surface through an etching process to generate a plurality of nucleation sites, and depositing a source material of a second material on the modified surface by using glancing angle deposition to form a plurality of nano-rods corresponding to the plurality of nucleation sites. | 11-04-2010 |
20100273203 | METHODS AND COMPOSITIONS FOR DETECTING METABOLITES - The present invention provides a metabolic profile, a database comprising a metabolic profile, a method for determining a metabolic profile, uses for a metabolic profile, and warfarin metabolites. | 10-28-2010 |
20100272871 | COATING COMPOSITION AND PROCESS FOR BAKED PRODUCTS TO IMPART THE ATTRIBUTES OF FRIED PRODUCTS - A composition and process for baked food products is provided to impart the sensorial attributes of fried food products. The composition is in the form of a batter coating, either powdered or wet, which is applied to a food product, and when baked, has the taste, texture and appearance of a fried food product. The batter coating includes at least an enzyme-modified starch or flour or other starch-containing material having oil absorbing capabilities. The enzyme-modified starch is plated with a liquid cooking oil in order to bring the liquid cooking oil into the process, and the batter coating retains the incorporated liquid cooking oil during processing to impart a fat fried texture, appearance and taste to the baked food product. | 10-28-2010 |
20100139563 | FABRICATION OF LARGE GRAIN POLYCRYSTALLINE SILICON FILM BY NANO ALUMINUM-INDUCED CRYSTALLIZATION OF AMORPHOUS SILICON - One aspect of the present invention relates to a method for fabricating a polycrystalline silicon film. In one embodiment, the method includes the steps of providing a substrate having a thermally-grown silicon dioxide layer, forming an amorphous silicon film on the thermally-grown silicon dioxide layer of the substrate, forming an aluminum layer on the amorphous silicon film to form a structure having the substrate, the amorphous silicon film and the aluminum layer, and annealing the structure at an annealing temperature for a period of time in an N | 06-10-2010 |
20100113861 | METALLIC NANOPARTICLES WITH COATED SHELLS AND APPLICATIONS OF SAME - A process or method for treating cancer. In one embodiment, the method includes the steps of providing a plurality of metallic nanoparticles, wherein each of the plurality of metallic nanoparticles has a core formed with a first metallic material, and a shell formed with a non-metallic material containing carbon, and wherein the shell is formed to enclose the metallic core completely, introducing said metallic nanoparticles into a mammal such that said metallic nanoparticles selectively target at least one type of cancerous cell, and subsequently applying at least one radio frequency of electromagnetic waves to said mammal for a period of time effective to induce skin currents in the cores of the first metallic material of said metallic nanoparticles to cause heat generated locally around targeted at least one type of cancerous cell to kill said cancerous cell. | 05-06-2010 |
20100097273 | NANO AND MICRO BASED ANTENNAS AND SENSORS AND METHODS OF MAKING SAME - A method of fabricating an antenna. In one embodiment, the method includes the steps of providing a substrate treated with a plasma treatment, providing a nanoparticle ink comprising nanoparticles, painting the nanoparticle ink on the substrate to form an antenna member in which the nanoparticles are connected, determining a feed point of the antenna member, and attaching an feeding port onto the substrate at the feed point to establish a contact between the feeding port and the antenna member. | 04-22-2010 |
20100086910 | Surface-modified single-walled carbon nanotubes and methods of detecting a chemical compound using same - A method for surface modification of single walled carbon nanotubes. In one embodiment, the method includes the steps of providing a detergent solution, adding a plurality of single walled carbon nanotubes into the detergent solution, performing a first sonication to disperse the single walled carbon nanotubes in the detergent solution, and performing a second sonication after the first sonication to make detergent encased single walled carbon nanotubes. At least one of the plurality of single walled carbon nanotubes is at least partially wrapped by one or more detergent molecules to make it a detergent encased single walled carbon nanotube. In one embodiment, the detergent comprises SDS, PSS or a combination of them. | 04-08-2010 |
20100035775 | MICROWAVE-ASSISTED SYNTHESIS OF CARBON AND CARBON-METAL COMPOSITES FROM LIGNIN, TANNIN AND ASPHALT DERIVATIVES AND APPLICATIONS OF SAME - A plurality of carbon-metal nanocomposites. In one embodiment, the plurality of carbon-metal nanocomposites includes a plurality of carbons with a molecular structure that shows a first peak in the range of 1585 to 1565 cm | 02-11-2010 |
20100032849 | MICROWAVE-ASSISTED SYNTHESIS OF CARBON AND CARBON-METAL COMPOSITES FROM LIGNIN, TANNIN AND ASPHALT DERIVATIVES - A process for synthesizing carbon-metal nanocomposites. In one embodiment, the process includes the steps of preparing a metal derivative or a metal chelated derivative of a carbon-containing precursor in solid form, and subjecting the metal derivative or metal chelated derivative of a carbon-containing precursor in solid form to microwave radiation at a frequency in the range of 900 MHz to 5.8 GHz, for a period of time effective to generate a heat flow from inside of the metal derivative or metal chelated derivative of a carbon-containing precursor in solid form to the outside such that the temperature of the metal derivative or metal chelated derivative of a carbon-containing precursor in solid form reaches 1,000° C. in less than 6 minutes with a temperature (T) derivative over time (t), ΔT/Δt, no less than 2.5° C./second to form carbon-metal nanocomposites. | 02-11-2010 |
20090263839 | ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD - The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample. | 10-22-2009 |
20090257945 | METHODS OF MAKING HORIZONTALLY ORIENTED LONG CARBON NANOTUBES AND APPLICATIONS OF SAME - An apparatus and method for synthesizing nanostructures in a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. In one embodiment, the method has the steps of placing a semiconductor plate having a film of a catalyst in the reaction zone such that the semiconductor plate is supported by the conductive susceptor; transporting a gas mixture having a feedstock gas having hydrocarbon and a carrier gas into the reaction zone of the chamber; inductively heating the reaction zone; and regulating the heating so that the temperature of the conductive susceptor increases from a first temperature to a second temperature when the gas mixture is introduced into the cavity of the chamber to allow nanostructures to be grown from the interaction of the gas mixture with the film of a catalyst of the semiconductor plate. | 10-15-2009 |
20090156932 | DEVICE AND METHOD FOR IN VIVO FLOW CYTOMETRY USING THE DETECTION OF PHOTOACOUSTIC WAVES - A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents. | 06-18-2009 |
20090124608 | CB2 Receptor Modulators In Neurodegenerative Diseases And Applications Of The Same - Compositions for the treatment of neurodegenerative diseases are disclosed. Methods of treating and monitoring progression of a neurodegenerative disease are disclosed. According to the present invention, a selective CB2 receptor modulator may be administered to a mammal for the treatment of a neurodegenerative disease. | 05-14-2009 |
20090060903 | Pharmaceutical Compositions Comprising an Anti-Teratogenic Compound and Applications of the Same - Pharmaceutical compositions comprising anti-teratogenic agents are disclosed. Additionally, pharmaceutical compositions comprising anti-neoplastic agents and anti-teratogenic agents are disclosed. Methods of assessing the teratogenicity of a compound are disclosed. The present invention further comprises applications of the aforementioned compositions and methods. | 03-05-2009 |
20090042850 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION - The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand. | 02-12-2009 |
20080318044 | TITANATE NANOWIRE, TITANATE NANOWIRE SCAFFOLD, AND PROCESSES OF MAKING SAME - In one aspect, the present invention relates to a synthetic nanostructure. In one embodiment, the synthetic nanostructure has a top region substantially comprising titanate nanowires, a middle region substantially comprising titanate nanoparticles and titanate nanowires, and a bottom region substantially comprising titanium, wherein some of the titanate nanowires of the top region are extending into the middle region, wherein the middle region is between the top region and the bottom region, and wherein some of the titanate nanowires of the top region are substantially perpendicular to the bottom surface of the titanium substrate. At least some of the titanate nanowires in the top region form 3D macroporous scaffolds with interconnected macropores. | 12-25-2008 |
20080274280 | Apparatus and methods for synthesis of large size batches of carbon nanostructures - An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The method includes the steps of transporting a gas mixture having an aerosolized catalyst, a feedstock and a carrier gas into the reaction zone of the reactor, inductively heating the reaction zone, and regulating a flow rate of the gas mixture to allow the catalyst to spend a sufficient amount of time in the reaction zone for the growth of nanostructures. | 11-06-2008 |
20080269159 | COMPOSITIONS AND METHODS FOR REGULATION OF SMOOTH MUSCLE CELLS AND BLOOD PRESSURE - The invention encompasses a composition for regulating smooth muscle cells. In particular, the invention encompasses a vector comprising a smooth muscle promoter operably-linked to a nucleic acid encoding a calcium-activated potassium channel. | 10-30-2008 |
20080264330 | Production of nanostructure by curie point induction heating - An apparatus for synthesizing nanostructures. In one embodiment, the apparatus includes a heating device that defines a reaction zone therein and a susceptor made of a ferromagnetic material with a Curie temperature and placed in the reaction zone, where the Curie temperature substantially corresponds to a temperature at which the growth of desired nanostructures occurs and the heating device is capable of heating the susceptor substantially at the Curie temperature. | 10-30-2008 |
20080229436 | METHODS FOR IDENTIFYING MODULATORS OF LIFESPAN AND RESISTANCE TO OXIDATIVE STRESS - The present invention provides methods for identifying agents that increase lifespan and increase resistance to oxidative and/or electrophilic stress. Also provided are methods for identifying biomarkers of longevity or identifying pathways governing longevity in response to phosphatidylinositol 3,4,5-triphosphate signaling. | 09-18-2008 |
20080223851 | APPARATUS AND METHODS FOR SYNTHESIS OF LARGE SIZE BATCHES OF CARBON NANOSTRUCTURES - An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The method includes the steps of transporting a gas mixture having an aerosolized catalyst, a feedstock and a carrier gas into the reaction zone of the reactor, inductively heating the reaction zone, and regulating a flow rate of the gas mixture to allow the catalyst to spend a sufficient amount of time in the reaction zone for the growth of nanostructures. | 09-18-2008 |
20080206791 | METHOD FOR DETECTING AN UNKNOWN CONTAMINANT CONCENTRATION IN A SUBSTANCE - A method for determining a concentration of a contaminant in a first sample, the method including producing the first sample, including adding a plurality of immuno-beads to a test substance; exposing a crystal microbalance immunosensor to the first sample; determining a change in a first motional resistance of the crystal microbalance immunosensor following exposure to the first sample (ΔR | 08-28-2008 |
20080199434 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR CONDITIONS - The present invention provides methods and compositions for treating a cardiovascular condition. In particular, provided is a method comprising administering to a subject an agent that increases the level and/or activity of angiotensin II type 2 receptors. Also provided is a method for evaluating the risk of having or developing a cardiovascular condition | 08-21-2008 |