| BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120018544 | WATER SPRAYS FOR DUST CONTROL ON MINING MACHINES - This invention refers to innovative water sprays applications to significantly improve coal and quartz dust control around a continuous miner Significant dust control is achieved through utilizing different types of sprays at locations on the top and sides of the miner chassis to create water curtains or shrouds of water around zones of high dust concentration and zones of high concentration dust transport. This is called “multiple lines of defense” spray system (MLD.) This invention also provides a method of reducing dust around a continuous miner by configuring a spray system, located at the top or sides of the cutter boom, thereby improving control of respirable dust. | 01-26-2012 |
| 20110250023 | ENGINEERED METAL CRIB FOR USE AS A SUPPORT STRUCTURE - This invention provides improvements through an engineered metal crib element for construction of cribs in mines to provide support between two surfaces and use of crib elements to construct cribs. The engineered metal crib element consists of a center elongate structural element and at least two outer load carrying steel members. The outer load carrying members may be composed of solid or hollow metal with one or more reinforcements within each load carrying member. Each outer load carrying member is attached to the center elongate element at the distal ends of the elongate structural element. The crib structure may be constructed by superimposing only these steel crib elements in 2×2 layers, 2×3 layers, 3×3 layers or in any other suitable layering system. The engineered metal crib elements are lightweight, have controllable higher stiffness and load carrying capacity than current wooden cribs, have engineered plastic yielding characteristics and allow much lower resistance to air flow in underground mine roadways. | 10-13-2011 |
| 20110160279 | METHODS FOR TREATMENT AND PREVENTION OF OTOTOXICITY BY siRNA - The present invention relates to methods for reducing and/or preventing ototoxicity caused by an ototoxic agent, noise or head and/or neck radiation. It is also directed to a method for preventing or reducing generation of reactive oxygen species in the inner ear of a patient. The methods of the present invention include administering at least one siRNA directed against TRPV1 mRNA, NOX3 mRNA or a combination thereof. | 06-30-2011 |
| 20110014302 | USE OF TRANSPLATIN TO PREVENT HEARING LOSS - Methods and compositions for treating and preventing toxic side effects of platinum-based chemotherapy agents are disclosed, in which transplatin is administered to a subject. Transplatin is shown to have protective effects against cisplatin-induced ototoxicity, nephotoxicity and neurotoxicity. Anti-inflammatory activity of transplatin is demonstrated and methods and compositions for treating and preventing inflammatory pain are described. | 01-20-2011 |
| 20100297722 | TRANSGENIC MOSS PRODUCING TERPENOIDS - The present invention generally relates to transgenic moss. One aspect of the invention provides a transgenic moss cell that produces or accumulates a terpenoid compound. Another aspect of the invention provides for methods of producing a terpenoid compound through culturing of the transgenic moss. | 11-25-2010 |
| 20100221073 | Engineered composite wooden crib for use as a mine support - This invention provides improvements through 1) a composite, engineered wooden support element for construction of cribs in mines to provide support between two surfaces, 2) use of support elements to construct cribs, and 3) a wedge system to provide substantial sustained preload on a crib. The wooden support element consists of a center elongate element wherein the wood grain runs transversely to the crib element loading direction, and at least two outer plate elements wherein the wood grain runs axially with the crib element loading direction. Each outer plate element is attached to a surface of the center elongate element using fastening means and the outer plate element wood grain direction is aligned transversely to the grain direction in the center elongate element. The crib structure may be constructed by superimposing only these support elements in 2×2 layers or in conjunction with solid prismatic wooden elements. A wooden wedge system with relatively low angle surface and with wood grain running axially is utilized to apply vertical preload. Due to high stiffness of the wedge in the axial direction, a substantial vertical preload can be applied and sustained to make cribbing structure a more efficient load carrying structure. The wooden support elements are lightweight, have controllable higher stiffness and load carrying capacity than current cribs, engineered yielding characteristics and allow much lower resistance to air flow in underground mine roadways. | 09-02-2010 |
| 20090247479 | Therapeutic Use of Methionine to Reduce the Toxicity of Aminoglycoside Antibiotics - Methods of preventing or reducing ototoxicity in patients undergoing treatment with therapeutically effective amounts of aminoglycoside antibiotics are provided. The methods comprise administering an effective amount of an otoprotective agent comprising methionine or a methionine-like moiety to said patient prior to, simultaneously with, or subsequently to administration of the aminoglycoside antibiotic. Combinations of these time periods can also be employed. | 10-01-2009 |
| 20090137421 | GENETIC SELECTION SYSTEM FOR IDENTIFICATION OF MicroRNA TARGET GENES - There is provided an expression cassette comprising a 3′-UTR cDNA library fragment, mammalian cells transfected with the expression cassette, and kits comprising the same. Furthermore, methods for identifying target genes for microRNAs are provided that utilize the expression cassette hereof. | 05-28-2009 |
