| Board of Regents, The University of Texas System Patent applications |
| Patent application number | Title | Published |
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| 20120127687 | FLEXIBLE CIRCUITS AND ELECTRONIC TEXTILES - Embodiments of wearable flexible devices and related methods are described herein. Other embodiments and related methods are also disclosed herein. | 05-24-2012 |
| 20120114559 | NANOIMPRINT LITHOGRAPHY FORMATION OF FUNCTIONAL NANOPARTICLES USING DUAL RELEASE LAYERS - Functional nanoparticles may be formed using at least one nanoimprint lithography step. In one embodiment, sacrificial material may be patterned on a multilayer substrate including one or more functional layers between removable layers using an imprint lithography process. At least one of the functional layers includes a functional material such as a pharmaceutical composition or imaging agent. The pattern may be further etched into the multilayer substrate. At least a portion of the functional material may then be removed to provide a crown surface exposing pillars. Removing the removable layers releases the pillars from the patterned structure to form functional nanoparticles such as drug or imaging agent carriers. | 05-10-2012 |
| 20120112385 | PATTERNING OF NON-CONVEX SHAPED NANOSTRUCTURES - Methods of making nano-scale structures with geometric cross-sections, including convex or non-convex cross-sections, are described. The approach may be used to directly pattern substrates and/or create imprint lithography templates or molds that may be subsequently used to directly replicate nano-shaped patterns into other substrates, such as into a functional or sacrificial resist to form functional nanoparticles. | 05-10-2012 |
| 20120111791 | Surface Deposition of Small Molecules to Increase Water Purification Membrane Fouling Resistance - The present invention includes methods and compositions for liquid separation and water purification. The present invention includes a purification membrane having a polymer matrix purification membrane that has been treated with hydroquinone, catechol, and/or dopamine coated membrane with a high water flux. | 05-10-2012 |
| 20120111324 | Dry Powder Drug Delivery Formulations, Methods of Use, and Devices Therefore - The present disclosure relates to systems, methods, and formulations for the pulmonary administration of one or more therapeutic agents, in dry powder form, in a single, large dose quantity. These formulations, methods, and systems are useful in the treatment of patients suffering from toxic or harmful gas exposure, such as nerve gas exposure, as well as in the treatment of patients suffering from diseases of the pulmonary system, including tuberculosis, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). | 05-10-2012 |
| 20120109560 | Remote Interrogation of a Passive Wireless Antenna Sensor - The condition of a structure using remote interrogation of a multi-state passive wireless antenna sensor that has a known resonant frequency when mounted on the structure. The passive wireless antenna sensor is connected to a remotely operated switching circuit that includes a photocell. An interrogation system transmits a series of radio frequency signals with sweeping frequencies around the known resonant frequency to the passive wireless antenna sensor, while simultaneously pulsing a laser to switch the passive wireless antenna sensor between a first state and a second state in which it is exposed to open-circuit or short-circuit conditions. A signal is reflected from the passive wireless antenna sensor in each of the first and second states, and a resonant frequency of the passive wireless antenna sensor is determined by normalizing the received signals to isolate the antenna mode. | 05-03-2012 |
| 20120108676 | AEROSOL-MEDIATED PARTICLE SYNTHESIS - Disclosed are aerosol-mediated methods for synthesizing particles for biomedical and drug delivery applications. The method is based on the production of particles from sprayed polymeric micro or nano-droplets obtained by, for example, an air-jet nebulization process that is followed by gelation and/or hardening in a crosslinking fluid, non-solvent, precipitating solvent, or supercritical fluid. | 05-03-2012 |
| 20120101010 | ALKOXY CARBOXYLATE SURFACTANTS - Provided herein are inter alia novel compositions and methods having application in a variety of fields including the field of enhanced oil recovery, the cleaning industry as well as groundwater remediation. In particular, the alkoxy carboxylate compounds and mixtures thereof presented herein can be used, inter alia, for the recovery of a large range of crude oil compositions from challenging reservoirs. | 04-26-2012 |
| 20120100203 | Fabrication of Biscrolled Fiber Using Carbon Nanotube Sheet - Fabrication of yarns or other shaped articles from materials in powder form (or nanoparticles or nanofibers) using carbon nanotube/nanofiber sheet as a platform (template). This includes methods for fabricating biscrolled yarns using carbon nanotube/nanofiber sheets and biscrolled fibers fabricated thereby. | 04-26-2012 |
| 20120100070 | Cyclic Peptide Analogues For Non-Invasive Imaging of Pancreatic Beta-Cells - Compositions, methods of using and methods of making a cyclic peptide analog imaging agent that includes at least portions of a peptide or protein that binds specifically to the GLP-1 receptor (GLP-1R) and the cyclic analog has one or more conformational restrictions including, but not limited to, lactam bridges, disulfide bridges, hydrocarbon bridges, and their combinations, salts and derivatives thereof wherein the cyclic analog is more stable than a non-cyclic analog when incubated in the presence of enzymes that degrade GLP-1 and have an increased serum half-live, wherein the cyclic analog comprises at least a portion of a GLP-1 peptide or at least a portion of an Exendin peptide salts, derivatives or combinations thereof. | 04-26-2012 |
| 20120094991 | 1, 4-Benzoxazine Compounds and Derivatives Thereof as Therapeutic Drugs for the Treatment of Neurodegenerative Conditions - The present invention includes compositions and methods for inhibiting kinase activity to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such as ischemic stroke comprising the step of providing the subject with a therapeutically affective amount of 1,4-benzoxazine compounds and derivatives thereof. | 04-19-2012 |
| 20120088832 | Anti-Adhesive Barrier Membrane Using Alginate and Hyaluronic Acid for Biomedical Applications - A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components. | 04-12-2012 |
| 20120085094 | Photovoltaic-Thermal (PV-T) System for Desalination - A photovoltaic-thermal (PV-T) system and a method of cooling photovoltaic (PV) cells in the system is described herein. Energy from an excitation source such as the sun hits the PV cells in the PV-T system causing heating that reduces PV efficiency. The PV cells are cooled by fluid in an intact heat-transfer system making a heated water byproduct while the PV cells release a form of energy. In addition, the PV-T system can be implemented in a desalination plant to harvest energy and heat for desalination processes. The present invention also includes methods for transferring heat from PV cells to the earth to improve PV performance and reduce thermal shock to the PV cells. | 04-12-2012 |
| 20120077936 | COVALENTLY FUNCTIONALIZED PARTICLES FOR SYNTHESIS OF NEW COMPOSITE MATERIALS - The present invention includes compositions and methods for synthesis of composite materials involving gas phase plasma polymerization to covalently plasma graft an organic molecule onto particles; covalently binding an organic monomer to the functionalized particles; and, polymerizing the organic monomers into hybrid polymer composite materials. | 03-29-2012 |
| 20120074879 | Methods and Apparatuses for Fault Management in Permanent Magnet Synchronous Machines Using the Field Reconstruction Method - Methods and apparatuses for detecting faults and optimizing phase currents in an electromechanical energy converter are disclosed. An example method comprises: measuring a current of a phase of the electromechanical energy converter, modeling the electromechanical energy converter with the current measurement input into a field reconstruction module, calculating a flux linkage of the electromechanical energy converter, comparing the flux linkage with a flux linkage from a no fault electromechanical energy converter, and optimizing the current of the phase of the electromechanical energy converter in response to the comparison. Other embodiments are described and claimed. | 03-29-2012 |
| 20120073515 | INTRATHECAL NEEDLE GUIDE APPARATUS - An apparatus for inserting a needle into an intrathecal space of small animals is disclosed, where the apparatus includes an animal positioning platform having a curved section, and a needle guide that rotates around the curved section, and to methods for using same. | 03-29-2012 |
| 20120071631 | Isolation and Characterization of Novel Green Fluorescent Proteins from Copepods - The isolation and characterization of two protein isoforms collected green fluorescent copepods is described herein. The new | 03-22-2012 |
| 20120065930 | VICINITY SENSOR SYSTEM AND RELATED SYSTEMS AND METHODS - Embodiments of vicinity sensor systems are described herein. Other embodiments and related methods are also disclosed herein. | 03-15-2012 |
| 20120058596 | METHODS AND APPARATUS FOR REAL-TIME MONITORING OF CADMIUM ION DURING SOLUTION GROWTH OF CADMIUM SULFIDE THIN FILMS - The present invention provides a reaction chamber to monitor a metal ion in solution during the formation of a metal-sulfide layer on a substrate. The reaction chamber houses a solution of an ammonium ion, a metal ion and a buffer. The reaction chamber includes an anion-selective electrode in the solution to monitor the metal ion that measures the metal ion during metal-ammonium complex formation, metal-thiourea complex formation, metal sulfide composition formation, metal sulfide layer formation or a combination thereof. | 03-08-2012 |
| 20120045394 | HUMAN AND MOUSE TARGETING PEPTIDES IDENTIFIED BY PHAGE DISPLAY - The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, including but not limited to gene therapy vectors. A novel class of gene therapy vectors is disclosed. Certain of the disclosed peptides have therapeutic use for inhibiting angiogenesis, inhibiting tumor growth, inducing apoptosis, inhibiting pregnancy or inducing weight loss. Methods of identifying novel targeting peptides in humans, as well as identifying endogenous receptor-ligand pairs are disclosed. Methods of identifying novel infectious agents that are causal for human disease states are also disclosed. A novel mechanism for inducing apoptosis is further disclosed. | 02-23-2012 |
| 20120043225 | Method and Apparatus for Electrocatalytic Amplification on Pre-Oxidized Measuring Electrode - The present invention includes methods and compositions having at least one nanoparticle for analyzing a chemical analyte. The device includes an electrochemical cell connected to a measuring apparatus, wherein the electrochemical cell comprises a container and at least one electrode comprising a surface modification; a solution within the container comprising one or more chemical analytes and one or more metal nanoparticles in the solution, wherein one or more electrocatalytic properties are generated by the one or more metal nanoparticles at the at least one electrode and the contact of individual nanoparticles can be measured. | 02-23-2012 |
| 20120038174 | Storing Carbon Dioxide and Producing Methane and Geothermal Energy from Deep Saline Aquifers - A novel idea involving the coupling of CO | 02-16-2012 |
| 20120035243 | DUAL TARGETING OF MIR-208 AND MIR-499 IN THE TREATMENT OF CARDIAC DISORDERS - The present invention provides a method of treating or preventing cardiac disorders in a subject in need thereof by inhibiting the expression or function of both miR-499 and miR-208 in the heart cells of the subject. In particular, specific protocols for administering inhibitors of the two miRNAs that achieve efficient, long-term suppression are disclosed. In addition, the invention provides a method for treating or preventing musculoskeletal disorders in a subject in need thereof by increasing the expression or activity of both miR-208 and miR-499 in skeletal muscle cells of the subject. | 02-09-2012 |
| 20120035114 | INHIBITORS OF STAT3 AND USES THEREOF - Compounds which inhibit the activity of signal transducer and activator of transcription 3 (STAT3) are provided together with methods of making and using the same. The compounds are designed to bind to the SH2 domain of STAT3, preventing STAT3 from binding to receptors for interleukin-6 family cytokines, growth factors such as the platelet-derived growth factor, the epidermal growth factor, vascular endothelial growth factor, and other signaling molecules such as leptin. Blocking these interactions prevents STAT3 from being phosphorylated on Tyr705, which is required for the dimerization of STAT3, translocation to the nucleus, binding to STAT3 response elements on promotors, and transcription of genes. In addition to these activities, binding to the SH2 domain of STAT3 breaks up pre-formed dimmers, thereby preventing the transcriptional activity of the inhibitor. | 02-09-2012 |
| 20120022322 | Methods and Devices for Treating Obesity - Methods and devices for treating obesity. Pressure is applied to gastric walls in at least one segment of a stomach such that the pressure distends the gastric walls and induces satiety. A hollow capsule can be used to distend the gastric walls. Alternatively, a doughnut- shaped ring may be inflated to an amount sufficient to create intragastric tension and induce satiety. A c-ring including at least one balloon may be placed at a segment of the stomach, where the balloon inflates to a size that creates tension at the segment. A biocompatible material can be injected into the fundus and antrum of the stomach to stiffen the gastric wall to create a fullness feeling. | 01-26-2012 |
| 20120021481 | ELECTROMECHANICAL LYSING OF ALGAE CELLS - Methods and electroporation devices for electrical treatment of algal cell cultures for release of lipids and proteins are described herein. The method of the present invention exploits the differences in electrical time constants for the media inside the cell and outside the cell to produce a net force to cause cellular lysis and extract cellular components. The method of the present invention can be used in the treatment of flocculated as well as unflocculated algal cell cultures. The device of the present invention provides efficient cell lysing in a low-energy cost set-up. | 01-26-2012 |
| 20120019362 | SINGLE ANTENNA SINGLE READER SYSTEM AND METHOD FOR LOCATING A TAG - A single antenna single reader (SASR) system and method for locating a tag. The reader connects to a single antenna that is in motion. The reader transmits an interrogation signal to the tag. The reader receives a response signal from the tag. The reader determines the range of the tag from the reader, the received signal strength (RSS) of the response signal at the reader from the tag, and the maximum correlation of the response signal at the reader from the tag. The reader determines the location of the tag using range of the tag from the reader, received signal strength and maximum correlation of the response signal. | 01-26-2012 |
| 20120009630 | STABILIZED REVERSE TRANSCRIPTASE FUSION PROTEINS - Stabilized reverse transcriptase fusion proteins including a thermostable reverse transcriptase connected to a stabilizer protein are described. Attaching the stabilizer protein to the thermostable reverse transcriptase stabilizes the fusion protein and can aid in its purification, provide increased solubility, allow for longer storage, or allow the fusion protein to be used under more rigorous conditions such as higher temperature. The stabilized reverse transcriptase fusion protein can also include a linker between the stabilizer protein and the thermostable reverse transcriptase. The stabilized reverse transcriptase fusion proteins are suitable for use in nucleic acid amplification methods such as the reverse transcription polymerase chain reaction and other applications involving cDNA synthesis. | 01-12-2012 |
| 20120000293 | Nanofiber Actuators and Strain Amplifiers - Nanofiber actuators and strain amplifiers having a material that generates a force or generates a displacement when directly or indirectly electrically driven. This material is an aerogel or a related low density or high density network comprising conducting fibers that are electrically interconnected and can substantially actuate without the required presence of either a liquid or solid electrolyte. Reversible or permanently frozen actuation is used to modify the properties of the actuator material for applications. | 01-05-2012 |
| 20110319303 | ALKYLPHOSPHOROFLUORIDOTHIOATES HAVING LOW WEAR VOLUME AND METHODS FOR SYNTHESIZING AND USING SAME - Alkylphosphorofluoridothioates containing alkyl groups of greater than four carbons which exhibit significantly lower wear volume compared to ZDDP, methods of making same with high yields, and methods of using same as lubricant additives. | 12-29-2011 |
| 20110316366 | DOUBLE STATOR SWITCHED RELUCTANCE APPARATUS - A switched reluctance apparatus and method of operating the same. The apparatus has an inner stator having a plurality of poles, a rotor disposed radially outward of the inner stator and having a plurality of segments serving as poles, and an outer stator disposed radially outward of the rotor and having a plurality of poles. A respective winding is disposed between every pair of adjacent poles of either stator. The apparatus operates with a plurality of separately excitable phases, a given phase being excited by energizing the windings corresponding to the given phase. Excitation of a given phase causes induction of magnetic fluxes traversing a region substantially confined to the region of the stators and rotor segments corresponding to the given phase, and causes a substantial amount of flux to enter rotor segments not in the radial direction but perpendicular to the radial direction. | 12-29-2011 |
| 20110311822 | HOLLOW NANOPARTICLES AND NANOCOMPOSITES AND METHODS OF MAKING HOLLOW NANOPARTICLES AND NANOCOMPOSITES - In one aspect, hollow nanoparticles are described herein. In some embodiments, a hollow nanoparticle comprises a metal shell and a cavity substantially defined by the shell, wherein the shell has a thickness greater than or equal to about 5 nm and the cavity has a curved surface. In another aspect, methods of making hollow nanoparticles are described herein. In some embodiments, a method of making hollow nanoparticles comprises forming a plurality of gas bubbles and forming a shell on the surface of at least one of the plurality of gas bubbles, wherein at least one of the gas bubbles is electrochemically generated. In another aspect, composite particles are described herein. In some embodiments, a composite particle comprises at least one nanoparticle and a polycrystalline metal shell substantially encapsulating at least one nanoparticle, wherein at least one surface of at least one nanoparticle is not in contact with the shell. | 12-22-2011 |
| 20110311454 | MOLECULES WITH EXTENDED HALF-LIVES, COMPOSITIONS AND USES THEREOF - The present invention provides molecules, including IgGs, non-IgG immunoglobulins, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. | 12-22-2011 |
| 20110305765 | PREPARATION AND METHODOLOGY OF SILK FIBROIN NANOPARTICLES - Disclosed are nanoparticles for delivery of drugs and/or nutraceuticals that include a fibroin polypeptide and a drug or nutraceutical, wherein the nanoparticle has a diameter of about 1 nm to about 500 nm, and compositions of the nanoparticles. The nanoparticles may further include a chitosan, or a proteoglycan such as decorin. Also disclosed are methods of delivering a drug and/or nutraceutical to a subject that involve administering to the subject nanoparticles of the present invention. Also disclosed are methods of making the nanoparticles of the invention, and kits that include the nanoparticles of the invention. | 12-15-2011 |
| 20110298149 | INORGANIC NANOWIRES - An inorganic nanowire having an organic scaffold substantially removed from the inorganic nanowire, the inorganic nanowire consisting essentially of fused inorganic nanoparticles substantially free of the organic scaffold, and methods of making same. For example, a virus-based scaffold for the synthesis of single crystal ZnS, CdS and free-standing L10 CoPt and FePt nanowires can be used, with the means of modifying substrate specificity through standard biological methods. Peptides can be selected through an evolutionary screening process that exhibit control of composition, size, and phase during nanoparticle nucleation have been expressed on the highly ordered filamentous capsid of the M13 bacteriophage. The incorporation of specific, nucleating peptides into the generic scaffold of the M13 coat structure can provide a viable template for the directed synthesis of a variety of materials including semiconducting and magnetic materials. Removal of the viral template via annealing can promote oriented aggregation-based crystal growth, forming individual crystalline nanowires. The unique ability to interchange substrate specific peptides into the linear self-assembled filamentous construct of the M13 virus introduces a material tenability not seen in previous synthetic routes. Therefore, this system provides a genetic tool kit for growing and organizing nanowires from various materials including semiconducting and magnetic materials. | 12-08-2011 |
| 20110293674 | MICRO-RNAs THAT MODULATE SMOOTH MUSCLE PROLIFERATION AND DIFFERENTIATION - The present invention relates to the identification of microRNAs that regulate smooth muscle cell proliferation and differentiation, including the miR-143/miR-145 cluster. Methods of treating restenosis and neointima formation by increasing expression of miR-143 and/or miR-145 are disclosed. The present invention also relates to the identification of two microRNAs, miR-486 and miR-422a, that regulate cell survival in the heart. Methods of treating or preventing cardiac hypertrophy, heart failure, or myocardial infarction by increasing expression of miR-486 and/or miR-422a in heart tissue are also disclosed. | 12-01-2011 |
| 20110290482 | Surfactant-Less Alkaline-Polymer Formulations for Recovering Reactive Crude Oil - Compositions and methods for oil recovery using a surfactant-less alkaline-polymer system in hard water or hard brine is described in the instant invention. The formulation further includes a chelating agent, an alkaline agent (which can be the same as the chelating agent), and a co-solvent. The formulations as disclosed herein are capable of forming a surfactant in-situ resulting in Winsor Type III micro-emulsions of low interfacial tension. | 12-01-2011 |
| 20110287956 | Nano-Scale Biosensors - Devices, systems, and methods for detecting protein-nucleic acid and cell-nucleic acid hybridization, using surface-tethered aptamer probes, without the use of labeling or target modification and capable of recycling. | 11-24-2011 |
| 20110287085 | LIPOSOMAL CURCUMIN FOR TREATMENT OF CANCER - The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analogue is administered parenterally in a pharmaceutically acceptable carrier. | 11-24-2011 |
| 20110281779 | Novel Anionic Polyalkoxy Group Comprising Surfactants on Basis of Guerbet-Alcohols, Method of Manufacture and Use in Enhanced Oil Recovery (EOR) Applications - Compositions and methods of synthesis of anionic surfactants by alkoxylation of a Guerbet alcohol (GA) having 12 to 36 carbon atoms using butylene oxide, and optionally propylene oxide and/or ethylene oxide followed by the incorporation of a terminal anionic group are described herein. The GA of the present invention is made by a facile and inexpensive method that involves high temperature base catalyzed dimerization of alcohols with 6 to 18 carbon atoms. The large hydrophobe ether surfactants of the present invention find uses in enhanced oil recovery (EOR) applications where it is used for solubilization and mobilization of oil and for environmental cleanup. Further, the hydrophobe alkoxylated GA without anionic terminal group can be used as an ultra-high molecular weight non-ionic surfactant. | 11-17-2011 |
| 20110280864 | Low Viscosity Highly Concentrated Suspensions - The present invention also provides a high concentration low viscosity suspension of an pharmaceutically acceptable solvent with one or more sub-micron or micron-sized non-crystalline particles comprising one or more proteins or peptides. Optionally one or more additives in the pharmaceutically acceptable solvent to form a high concentration low viscosity suspension with a concentration of at least 20 mg/ml and a solution viscosity of between 2 and 100 centipoise that is suspendable upon shaking or agitation, wherein upon delivery the one or more sub-micron or micron-sized peptides dissolves and do not form peptide aggregates syringeable through a 21 to 27-gauge needle. | 11-17-2011 |
| 20110278203 | SEPARATION OF PARTICLES FROM A FLOWING STREAM - This invention provides a process for separating particles. The process is particularly effective in separating particles such as isotopes of a chemical element. In carrying out the process, at least one particle stream that comprises the particles that are to be separated is contacted with a separate carrier gas stream to produce a mixed stream. A portion of the particles in the mixed stream is magnetically activated, and the magnetically activated particles are separated from non-magnetically activated particles the mixed stream. | 11-17-2011 |
| 20110277827 | NANOSTRUCTURED SOLAR CELL - Systems and methods for fabrication of nanostructured solar cells having arrays of nanostructures are described, including nanostructured solar cells having a repeating pattern of pyramid nanostructures, providing for low cost thin-film solar cells with improved PCE. | 11-17-2011 |
| 20110275947 | CARDIOVASCULAR POWER SOURCE FOR AUTOMATIC IMPLANTABLE CARDIOVERTER DEFIBRILLATORS - Aspects according to the present invention provide a method and implant suitable for implantation inside a human body that includes a power consuming means responsive to a physiological requirement of the human body, a power source and a power storage device. The power source comprises a piezoelectric assembly that is configured to generate an electrical current when flexed by the tissue of the body and communicate the generated current to the power storage device, which is electrically coupled to the power source and to the power consuming means. | 11-10-2011 |
| 20110274703 | DETECTION AND TREATMENT OF NON-DERMAL FIBROSIS - The invention relates to methods for the diagnosis, prognosis, and treatment of non-dermal fibrosis, including lung (or pulmonary) fibrosis. | 11-10-2011 |
| 20110274361 | DETERMINING QUALITY OF AN IMAGE OR VIDEO USING A DISTORTION CLASSIFIER - Techniques and structures are disclosed in which one or more distortion categories are identified for an image or video, and a quality of the image or video is determined based on the one or more distortion categories. The image or video may be of a natural scene, and may be of unknown provenance. Identifying a distortion category and/or determining a quality may be performed without any corresponding reference (e.g., undistorted) image or video. Identifying a distortion category may be performed using a distortion classifier. Quality may be determined with respect to a plurality of human opinion scores that correspond to a particular distortion category to which an image or video of unknown provenance is identified as belonging. Various statistical methods may be used in performing said identifying and said determining, including use of generalized Gaussian distribution density models and natural scene statistics. | 11-10-2011 |
| 20110267012 | Methods and Apparatuses for Elimination of Torque Pulsation in Doubly Fed Induction Generators Using the Field Reconstruction Method - Methods and apparatuses for substantially eliminating torque pulsation in a doubly fed induction machine are disclosed. An example method comprises: measuring a stator current of the doubly fed induction machine, measuring a rotor current of the doubly fed induction machine, calculating a total magnetic flux density in an airgap of the doubly fed induction machine, calculating a tangential force density, calculating an electromagnetic torque, repeating the calculation of the electromagnetic torque over one electrical cycle to estimate a torque pulsation, determining a new rotor current that substantially eliminates the torque pulsation by referencing a set of optimal rotor currents in a look-up table, and changing the rotor current in response to the determination. Other embodiments are described and claimed. | 11-03-2011 |
| 20110251075 | SYSTEM AND METHOD FOR THE ANALYSIS OF BODILY FLUIDS - A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. | 10-13-2011 |
| 20110224232 | Treatment of Pulmonary Fungal Infection With Voriconazole via Inhalation - A method of treating fungal infection by pulmonary administration of a solution of voriconazole and cyclodextrin is provided The fungal infection can be a pulmonary infection. The solution can be an inhalable aqueous formulation that can be administered via the mouth or nose. The cyclodextrin can be a water soluble cyclodextrin derivative such as sulfoalkyl ether cyclodextrin. The formulation can be administered via a spray device or nebulizer. | 09-15-2011 |
| 20110224099 | BEAD BOUND COMBINATORIAL OLIGONUCLEOSIDE PHOSPHOROTHIOATE AND PHOSPHORODITHIOATE APTAMER LIBRARIES - The present invention includes composition and methods for making and using a combinatorial library having two or more beads, wherein attached to each bead is a unique nucleic acid aptamer that have disposed thereon a unique sequence. The library aptamers may be attached covalently to the one or more beads, which may be polystyrene beads. The aptamers may include phosphorothioate, phosphorodithioate and/or methylphosphonate linkages and may be single or double stranded DNA, RNA or even PNAs. | 09-15-2011 |
| 20110222710 | METHOD AND APPARATUS FOR AUTOMATICALLY REDUCING A VOLUME LEVEL OF AN AUDIO SIGNAL PROVIDED TO A USER - The present invention provides a method of automatically reducing a volume level of an audio signal provided to a user. An audio signal is received, the audio signal is provided to the and a current hearing threshold for the user based on one or more psychophysical or electrophysiological responses of the user to the audio signal provided to the user is determined. A temporary threshold shift (TTS) based on the current hearing threshold is determined. If the TTS is above the specified TTS, the volume level of the audio signal provided to the user is automatically reduced. | 09-15-2011 |
| 20110221906 | Multiple Camera System for Automated Surface Distress Measurement - The present invention provides a system for imaging a surface in real time. The system includes two or more real time digital imaging devices positioned to capture two or more images of a surface, wherein the two or more real time digital imaging devices are set in different exposure modes; and an image processing device that processes the two or more images, wherein the two or more images are complementary and together form a complete shadow-free image of the surface. The two or more real time digital imaging devices are line-scan cameras or other types of digital cameras, wherein each of the two or more real time digital imaging devices is independently set at an under-exposure mode, an over-exposure mode or an intermediate exposure mode. Multi-exposed images are fused together through a multi-scale decomposition and reconstruction method for crack detection. | 09-15-2011 |
| 20110217747 | LANDFILL METHANE ENHANCEMENT PROCESS - A zero-discharge landfill process is disclosed herein. The process described in the present invention recycles the exhaust gases from a combustion engine which reheats the landfill and provides moisture. Additionally, the CO | 09-08-2011 |
| 20110212843 | STRUCTURE BASED AND COMBINATORIALLY SELECTED OLIGONUCLEOSIDE PHOSPHOROTHIOATE AND PHOSPHORODITHIOATE APTAMER TARGETING AP-1 TRANSCRIPTION FACTORS - The present invention includes composition and methods for making and using a combinatorial library to identify modified thioaptamers that bind to, and affect the immune response of a host animal, transcription factors such as IL-6, NF-κB, AP-1 and the like. Composition and methods are also provided for the treatment of viral infections, as well as, vaccines and vaccine adjuvants are provided that modify host immune responses. | 09-01-2011 |
| 20110203927 | Method for Measuring Carbon Nanotubes Taken-Up by a Plurality of Living Cells - The present invention provides methods, apparatuses and kits for determining the presence and the concentration of nanoparticles in a given area, solution or region via cellular uptake and/or adsorption monitored through laboratory equipment. For example, the present invention provides a method of quantifying one or more nanoparticles by incubating a nanoparticle solution comprising one or more nanoparticles with one or more cells; isolating the one or more cells; lysing the one or more cells to release a cell lysate; separating the cell lysate electrophoretically on a gel; digitizing the gel to form a gel image; quantifying the nanoparticle intensity in the gel image; and correlating the nanoparticle intensity to a cell-associated nanoparticle concentration. | 08-25-2011 |
| 20110201531 | Method for Treating Hydrocarbon-Bearing Formations with Fluorinated Epoxides - A method of treating a hydrocarbon-bearing formation with a fluorinated epoxide and a treated hydrocarbon-bearing formation. A method of making proppants is also disclosed, which includes combining a plurality of particles with a fluorinated epoxide. The particles comprise at least one of sand, resin-coated sand, ceramic, thermoplastic, clay, bauxite, nut or seed shells, fruit pits, or wood. A particle treated with a ring-opened product of a fluorinated epoxide is also disclosed, wherein the particle comprises one of sand, resin-coated sand, ceramic, thermoplastic, clay, bauxite, nut or seed shells, fruit pits, or wood. | 08-18-2011 |
| 20110190174 | Styrylphenol Alkoxylate Sulfate as a New Surfactant Composition for Enhanced Oil Recovery Applications - A method of making a styryl phenol alkoxylate sulfate surfactant by alkoxylation of a styryl phenol using propylene oxide (PO) and/or ethylene oxide (EO) followed by a sulfation reaction. The styrylphenol alkoxylate sulfate surfactant of the present invention is made by a facile and inexpensive method. The large hydrophobe surfactants of the present invention find uses in EOR applications where it is used for solubilization and mobilization of oil optionally containing asphaltene, and for environmental cleanup. Further, the unsulfated version of the large hydrophobe styrylphenol alkoxylate surfactant of the present invention can be used as an ultra-high molecular weight non-ionic surfactant. | 08-04-2011 |
| 20110183435 | Biodegradable Photoluminescent Polymers - The present invention describes a novel elastomeric biodegradable photoluminescent polymer (BPLP). The BPLPs of the present invention possess great processability and tunable fluorescence emission characteristics and are cell-compatible and biodegradable. The BPLPs of the present invention can serve as both implant materials and bioimaging probes. | 07-28-2011 |
| 20110182946 | Formation of Nanostructured Particles of Poorly Water Soluble Drugs and Recovery by Mechanical Techniques - The present invention provides a composition and method of forming an amorphous drug-loaded particle by forming one or more amorphous drug-loaded nanoparticles comprising one or more active agents stabilized by one or more polymers, desolvating the one or more amorphous drug-loaded nanoparticles to form one or more flocculated amorphous drug-loaded nanoparticles, filtering the one or more flocculated amorphous drug-loaded nanoparticles and drying the one or more flocculated amorphous drug-loaded nanoparticles to form amorphous drug-loaded particles. | 07-28-2011 |
| 20110174734 | Non-Dispersive Process for Insoluble Oil Recovery From Aqueous Slurries - The development and application of a novel non-polar oil recovery process utilizing a non-dispersive solvent extraction method to coalesce and recover oil from a bio-cellular aqueous slurry is described herein. The process could apply to recovery of algal oil from a lysed algae slurry, recovery of Omega fatty acids from a bio-cellular aqueous feed, recovery of Beta-carotene from a bio-cellular aqueous feed and for the removal from produced water in oil production and similar type applications. The technique of the present invention utilizes a microporous hollow fiber (MHF) membrane contactor. The novel non-polar oil recovery process described herein can be coupled to a collecting fluid (a non-polar solvent such as heptane, a biodiesel mixture or the previously extracted oil) that is circulated through the hollow fiber membrane. In cases where the biodiesel mixture or the previously extracted oil is used the solvent recovery step (e.g. distillation) can be eliminated. | 07-21-2011 |
| 20110171309 | Compositions and Methods for Composite Nanoparticle Hydrogels - Provided herein are systems, methods, and compositions for composite nanoparticle hydrogel networks and systems responsive to a first temperature. | 07-14-2011 |
| 20110166465 | SYSTEM, METHOD, AND PROGRAM PRODUCT FOR DELIVERING MEDICAL SERVICES FROM A REMOTE LOCATION - A system, program product, and methods related to enhanced medical services delivery to geographically distributed patient populations by remotely located physicians are provided. An embodiment of the system includes a remote medical services server, a plurality of patient electronic medical records stored in the memory of the remote medical services server, and a remote medical services program product stored in the memory of the remote medical services server adapted to access the plurality of patient electronic medical records to thereby allow display of and data entry in a selected patient electronic medical record. A patient medical service delivery station captures patient video images and displays remote physician video images. A remote physician medical service delivery suite in communication with the patient medical service delivery station through the communications network captures remote physician video images and displays patient video images and patient electronic medical records, to allow the remote physician to perform remote patient medical service delivery. | 07-07-2011 |
| 20110164879 | Compact Multi-Port Optical Signal Processor - In a method and system to fabricate a compact optical device, a periodic group-delay device (PGDD) includes N optical input ports, N being a positive integer number, each port being configured to include one or more wavelength-division- multiplexing (WDM) channels; N corresponding optical output ports, each port being configured to include one or more WDM channels. The PGDD also includes a first slab waveguide region (FSWR) coupled to the N optical input ports, a second slab waveguide region (SSWR) coupled to the said N optical output ports, a first optical grating coupled to the FSWR, a second optical grating coupled to the SSWR, and; a third slab waveguide region (TSWR) coupled to at least one of the first and second optical gratings. The TSWR is configured to provide a configurable amount of dispersion to the N optical output ports. Optical signals carried by each WDM channel are processed concurrently and independently. | 07-07-2011 |
| 20110154288 | Automation Support For Domain Modeling - A domain model generator (DMG) for an integrated development environment (IDE) guides a software engineer through a process of identifying domain-specific concepts for a domain of an object-oriented software application. The DMG also helps the engineer to classify the domain-specific concepts as pertaining to particular object-oriented modeling concepts for the object-oriented software application. Those modeling concepts may include classes, attributes, inheritance, etc. In addition, the DMG may automatically generate a Unified Modeling Language (UML) domain diagram, based at least in part on the domain-specific concepts and the corresponding modeling concepts. Other embodiments are described and claimed. | 06-23-2011 |
| 20110144029 | Model Systems and Materials for the Study and Treatment of Neurodegenerative Diseases - The present invention provides models for studying the development of, and/or pathologies associated with neurodegenerative diseases, and agents that can modulate such development and/or pathologies. | 06-16-2011 |
| 20110136704 | Methods of Treating a Hydrocarbon-Bearing Formation, a Well Bore, and Particles - Methods of treating articles using a compound represented by formula: (I) wherein each of X and Y is independently a thiol, a halogen, a hydrogen, a hydroxyl, a hydroalkyl, a carboxylic acid, an aldehyde, a carboxylic ester, or a carboxamide; R′ is hydrogen, alkyl, or aryl; and x and y are each independently 0 to 10, wherein x+y is at least 1 and articles treated by such methods. In some embodiments, the article is a hydrocarbon-bearing formation. In some embodiments, the article is a particle, and the method further comprises treating the article with a fluorochemical comprising at least one fluoroaliphatic segment and at least one hydrophilic segment. In some embodiments, the method is used to treat a well bore. | 06-09-2011 |
| 20110125333 | System, Program Products, and Methods For Controlling Drilling Fluid Parameters - Embodiments of systems, program product, and methods for controlling drilling fluid pressures are provided. These embodiments, for example, can provide dynamic density control with highly adaptive, real-time, process-control and are scalable to any rig, large or small, on land or water. Combined static and dynamic stresses and displacements can be determined continuously at strategic locations in and around the wellbore of a well so that insitu and operational induced pressure window limitations at specific weak-points or other locations of interest are controlled. | 05-26-2011 |
| 20110125076 | PHOTOKINETIC OCULAR DRUG DELIVERY METHODS AND APPARATUS - The present invention relates generally to transscleral, transcorneal, and transocular delivery of biologically active substances through the tissues, blood vessels and cellular membranes of the eyes of patients without causing damage to the cellular surface, tissue or membrane. The invention provides compositions and methods for enhanced transscleral, transcorneal and transocular delivery of biologically active substances using pulsed incoherent light, and particularly the transcleral, transcorneal or transocular delivery of high molecular weight biologically active substances to a patient using pulsed incoherent light. The invention further provides a device for the application of the pulsed incoherent light to cellular surfaces and membranes of the eye of a subject using those compositions and methods. | 05-26-2011 |
| 20110124765 | Versatile Biodegradable Elastic Polymers Featured with Dual Crosslinking Mechanism for Biomedical Applications - The present invention provides a dual crosslinked biodegradable polymer and methods of making and using the polymer. The dual crosslinked biodegradable polymer composition includes a multifunctional monomer; a diol; and an unsaturated di-acid at least partially polymerized to form a network and photocrosslinked into a dual crosslinked polymer network. | 05-26-2011 |
| 20110118133 | METHODS TO IDENTIFY PATIENTS AT RISK OF DEVELOPING ADVERSE EVENTS DURING TREATMENT WITH ANTIDEPRESSANT MEDICATION - The invention provides a method of screening patients to identify those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation comprising: (a) obtaining a sample of genetic material from the patients, and (b) assaying the sample for the presence of a genotype in the patients which is associated with an increased risk of treatment-emergent suicidal ideation, wherein the genotype is characterized by a polymorphism in a gene selected from the group consisting of glutamine receptor, ionotropic, kainate 2 (GRIK2); glutamate receptor ionotropic AMPA 3 (GRIA3); and combinations thereof. | 05-19-2011 |
| 20110112409 | ROTATING CATHETER PROBE USING A LIGHT-DRIVE APPARATUS - The invention is a rotating tip catheter-imaging probe where electromagnetic energy is delivered to the distal end of a catheter and converted to mechanical energy using a light drive apparatus. The mechanical energy is then used to rotate a mirror that redirects light in fixed pattern on a sample. The rotating element of the light drive apparatus contains vanes, which rotate about an axis and positioned with bearings to minimize friction. A chamber encompasses the rotating element and is set to a vacuum pressure. The rotational speed of the catheter tip can be controlled by varying the optical power delivered to the vanes, the vacuum pressure in the chamber, or by a braking mechanism applied to the rotating element. The vanes may be shaped in a particular geometry to increase forces on the vanes from thermally driven gas flow. | 05-12-2011 |
| 20110110138 | Methods and Systems for Phase Current Reconstruction of AC Drive Systems - Methods and systems for phase current reconstruction are disclosed. An example method comprises: sampling a current from a power stage comprising: three phase legs, a current sensor to measure a dc-link current, and three more current sensors configured to measure three summations of currents for the power stage, storing the sampled current into a current stack if the sampled current comes from a survived sensor and is one of the phase currents from the switching state in the state stack, and reconstructing an unknown phase current by using the previously stored currents along with the sampled current to calculate the unknown phase current. Other embodiments are described and claimed. | 05-12-2011 |
| 20110104306 | NOVEL COMPOSITIONS AND METHODS FOR THE IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF HUMAN CANCERS - The present invention is directed to the identification of markers that can be used to determine whether tumors are sensitive or resistant to a therapeutic agent. The present invention is also directed to the identification of therapeutic targets. The invention features a number of “sensitivity markers.” These are markers that are expressed in most or all cell lines that are sensitive to treatment with an agent and which are not expressed (or are expressed at a rather low level) in cells that are resistant to treatment with that agent. The invention also features a number of “resistance markers.” These are markers that are expressed in most or all cell lines that are resistant to treatment with an agent and which are not expressed (or are expressed at a rather low level) in cells that are sensitive to treatment with that agent. The invention also features marker sets that can predict patients that are likely to respond or not to respond to an agent. | 05-05-2011 |
| 20110097960 | Testing Electronic Textiles During Assembly and Electronic Textile Displays - Ribbons containing e.g. inorganic NMOS devices are assembled in electrical contact with ribbons containing e.g. PMOS devices (preferably organic) to enable flexible electronic textile circuits, e.g. displays, to be inexpensive and practical for a wide for a variety of functions. The use of ribbons provides flexibility, reduces costs, and allows testing during assembly and different processes to be efficiently used for different components. This is apparently the first time that ribbons (especially inorganic-device-containing ribbons) have been interconnected to form a flexible CMOS electronic textile. | 04-28-2011 |
| 20110097416 | Compositions and Methods for Thermo-Sensitive Nanoparticles and Magnetic Nanoparticles - Provided herein are systems, methods, and compositions for polymer nanoparticles and polymer magnetic nanoparticles. More particularly, the polymer nanoparticles and polymer magnetic nanoparticles are temperature sensitive and responsive to a first temperature. | 04-28-2011 |
| 20110092388 | COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF BREAST CANCER - The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided. | 04-21-2011 |
| 20110092125 | Testing Electronic Textiles During Assembly and Electronic Textile Displays - Ribbons containing e.g. inorganic NMOS devices are assembled in electrical contact with ribbons containing e.g. PMOS devices (preferably organic) to enable flexible electronic textile circuits, e.g. displays, to be inexpensive and practical for a wide for a variety of functions. The use of ribbons provides flexibility, reduces costs, and allows testing during assembly and different processes to be efficiently used for different components. This is apparently the first time that ribbons (especially inorganic-device-containing ribbons) have been interconnected to form a flexible CMOS electronic textile. | 04-21-2011 |
| 20110091647 | GRAPHENE SYNTHESIS BY CHEMICAL VAPOR DEPOSITION - Processes for synthesizing graphene films. Graphene films may be synthesized by heating a metal or a dielectric on a substrate to a temperature between 400° C. and 1,400° C. The metal or dielectric is exposed to an organic compound thereby growing graphene from the organic compound on the metal or dielectric. The metal or dielectric is later cooled to room temperature. As a result of the above process, standalone graphene films may be synthesized with properties equivalent to exfoliated graphene from natural graphite that is scalable to size far greater than that available on silicon carbide, single crystal silicon substrates or from natural graphite. | 04-21-2011 |
| 20110091526 | Parasite Vaccine - Compositions and methods for the development and use of a vaccine that includes one or more FusM antigens in a carrier adapted to trigger a FusM-specific immune response in the human blood stream are disclosed herein. | 04-21-2011 |
| 20110086850 | RADIOSENSITIZATION OF TUMORS WITH INDAZOLPYRROLOTRIAZINES FOR RADIOTHERAPY - Provided herein is a method of radiosensitizing a tumor in a subject, which comprises administering to the subject a radiosensitizing amount of an indazolpyrrolotriazine of Formula I. Also provided herein is a method of treating a tumor in a subject, which comprises the steps of administering to the subject a radiosensitizing amount of an indazolpyrrolotriazine of Formula I, and a therapeutically effective fraction of radiation. | 04-14-2011 |
| 20110086464 | TUNING OF FE CATALYSTS FOR GROWTH OF SPIN-CAPABLE CARBON NANOTUBES - Growing spin-capable multi-walled carbon nanotube (MWCNT) forests in a repeatable fashion will become possible through understanding the critical factors affecting the forest growth. Here we show that the spinning capability depends on the alignment of adjacent MWCNTs in the forest which in turn results from the synergistic combination of a high areal density of MWCNTs and short distance between the MWCNTs. This can be realized by starting with both the proper Fe nanoparticle size and density which strongly depend on the sheet resistance of the catalyst film. Simple measurement of the sheet resistance can allow one to reliably predict the growth of spin-capable forests. The properties of pulled MWCNTs sheets reflect that there is a relationship between their electrical resistance and optical transmittance. Overlaying either 3, 5, or 10 sheets pulled out from a single forest produces much more repeatable characteristics. | 04-14-2011 |
| 20110083360 | IMMOBILIZED RESINS FOR ALGAL OIL EXTRACTION - A reverse phase extraction method for the recovery of triglycerides from aqueous slurries of algae is described herein. The present invention discloses the use of immobilized anion exchange and lipid binding resins. As the algae flows past the resin, triglycerides adhere while the bulk of the algae flows through. The lipids, useful for generating biofuels are then are eluted off the resin. The method of the present invention does not require prior drying of the algae, is inexpensive, and does not destroy the algal biomass which can be used for other purposes. | 04-14-2011 |
| 20110071057 | METHOD OF MANUFACTURE AND USE OF LARGE HYDROPHOBE ETHER SULFATE SURFACTANTS IN ENHANCED OIL RECOVERY (EOR) APPLICATIONS - The present invention describes the method of making anionic ether sulfate surfactants by alkoxylation of a GA using PO and/or EO followed by a sulfation reaction. The GA of the present invention is made by a facile and inexpensive method that involves high temperature base catalyzed dimerization of a linear alcohol. The ether sulfate surfactants of the present invention find uses in EOR applications where it is used for solubilization and mobilization of oil and for environmental cleanup. | 03-24-2011 |
| 20110066217 | Altering temperature in a mammalian body - The present application relates to systems and methods for altering temperature in a mammalian body. Optionally, the systems and methods can be used to lower or raise core body temperature of a mammalian subject. Optionally, the systems and methods can be used to lower or raise the temperature of glabrous skin of a mammalian subject. | 03-17-2011 |
| 20110065505 | VIRTUAL REALITY ENTERTAINMENT SYSTEM FOR TREATMENT OF PHANTOM LIMB PAIN AND METHODS FOR MAKING AND USING SAME - Visual feedback systems and methods implementing the system are disclosed that use computer generated images of lost limbs to display visual images of the limb being used in activities on a display unit providing visual feedback of the use of the missing limb to the brain to ameliorate, reduce, treat or eliminate phantom limb pain. | 03-17-2011 |
| 20110065161 | BIPOLAR SOLID STATE MARX GENERATOR - A high-voltage bipolar rectangular pulse generator using a high efficiency solid-state boosting front-end and an H-bridge output stage is described. The topology of the circuit generates rectangular pulses with fast rise time and allows easy step-up input voltage. In addition, the circuit is able to adjust positive or negative pulse width, dead-time between two pulses, and operating frequency. The intended application for such circuit is algae cell membrane rupture for oil extraction, although additional applications include biotechnology and plasma sciences medicine, and food industry. | 03-17-2011 |
| 20110060538 | Estimation of State-Of-Health in Batteries - Methods and apparatuses for estimation of a state-of-health in a battery are disclosed. An example method comprises: determining if a terminal voltage of the chemical battery differs from a calculated terminal voltage; in response to determining that the terminal voltage of the chemical battery differs from the calculated terminal voltage, calculating a range of voltages by taking the convolution of a terminal current of the chemical battery with a range of impulse responses from a look up table of impulse responses corresponding to different states-of-health; comparing the terminal voltage of the chemical battery with the range of calculated voltages to determine a second impulse response that corresponds to the case where the terminal voltage matches the calculated voltage; and using the look up table of impulse responses corresponding to different states-of-health to determine the state-of-health of the chemical battery from the second impulse response. Other embodiments are described and claimed. | 03-10-2011 |
| 20110060152 | Methods and Systems for Improved Biodiesel Production - In a method and system to produce biodiesel using an improved catalytic transesterification process, a first reactant and a second reactant are dispersed to form a laminar slug flow pattern within a microchannel of a microreactor, the first reactant and the second reactant being immiscible. The first reactant and the second reactant are mixed, thereby triggering a reaction between them to produce the biodiesel and glycerol, the mixing being convection-enhanced by shear stress induced circulation occurring within each slug of the reactants. The reaction takes place under a pressure that is less than 5 psi and under a temperature that is less than 70 degrees Celsius. Separation of the glycerol from the biodiesel occurs simultaneously with the mixing. Several microreactors are coupled in parallel to improve throughput of the biodiesel. | 03-10-2011 |
| 20110059900 | Diagnosing and treating hormone resistant cancers - Provided herein are methods and compositions related to diagnosing and treating hormone resistant cancers. | 03-10-2011 |
| 20110059873 | PROCESS OF USING HARD BRINE AT HIGH ALKALINITY FOR ENHANCED OIL RECOVERY (EOR) APPLICATIONS - The present invention describes the use of EDTA and/or alkali treated hard brine at high pH for making ASP formulations for EOR applications. | 03-10-2011 |
| 20110059872 | COMPOSITIONS AND METHODS FOR CONTROLLING THE STABILITY OF ETHERSULFATE SURFACTANTS AT ELEVATED TEMPERATURES - The present invention describes the method of making an ether sulfate surfactant solution hydrolytically stable by adding one or more alkalinity generating agents at levels greater than 0.05%. The surfactant solutions of the present invention have half-lives >8 months at 100° C. and find uses in EOR applications, environmental cleanups, detergent industry, and any other surfactant based high temperature applications. | 03-10-2011 |
| 20110055327 | System and Method for Service Management - In one aspect, a method for managing a health care plan is disclosed. The method may include accepting input characterizing a service management objective; accepting input representing a message for a client; and affecting the client's behavior with respect to the service management objective by presenting by electronic communication the message to the client according to a schedule. | 03-03-2011 |
| 20110054445 | Devices and Methods for Treatment of Eye Disease - Methods, systems, and apparatus for delivering drugs for treatment of eye disease are described. For example, the methods, systems, and apparatus can be optionally used to treat wet age-related macular degeneration. In some examples, an eye disease is treated by implanting a device comprising a sealed container into the diseased eye. A dosage of drug for treating the diseased eye is disposed within the sealed container. The dosage of the drug is selectively released from the sealed container of the implanted device into eye tissue. The released dosage treats the eye disease. | 03-03-2011 |
| 20110049096 | Functional Nanoparticles - Functional nanoparticles may be formed using at least one nano-lithography step. In one embodiment, sacrificial material may be patterned on a multi-layer substrate using an imprint lithography system. The pattern may be further etched into the multi-layer substrate. Functional material may then be deposited on multi-layer substrate and solidified. At least a portion of the functional material may then be removed to provide a crown surface exposing pillars. Pillars may be removed from multi-layer substrate forming functional nanoparticles. | 03-03-2011 |
| 20110048721 | DI-FUNCTIONAL SURFACTANTS FOR ENHANCED OIL RECOVERY - The present invention describes the synthesis and use of cleavable di-functional anionic surfactants for enhanced oil recovery applications and/or the use of sacrificial surfactants. | 03-03-2011 |
| 20110048518 | Nanostructured thin film inorganic solar cells - Inorganic solar cells having a nano-patterned p-n or p-i-n junction to reduce electron and hole travel distance to the separation interface to be less than the magnitude of the drift length or diffusion length, and meanwhile to maintain adequate active material to absorb photons. Formation of the inorganic solar cells may include one or more nano-lithography steps. | 03-03-2011 |
| 20110047381 | SAFEMASHUPS CLOUD TRUST BROKER - The present invention provides a new method for policy enforcement in a virtualized or cloud environment. We break down the environment into layers, which are further sub-divided into security units. Each security unit has a security profile based on its own security properties and those of the layers below. The security profile also reflects the floor, ceiling and wall security properties. Each security unit has an agent which is used to establish communications with other security units. Such communication is mediated by a cloud trust broker which determines if the communication is permitted based on access control list or else retrieves the security profiles and applies pre-defined rules. If the communications are allowed the cloud trust broker runs a mutual authentication and key distribution protocol that results in the two security units obtaining a session key which they can then use for further communications which can proceed directly. | 02-24-2011 |
| 20110042345 | METHODS FOR MANUFACTURING CHUCKING SYSTEMS - Methods for manufacturing chucking systems are described. Generally, a plurality of flow holes may be provided in an optical flat. A surface of the optical flat may be masked and patterned to provide a desired feature (e.g., pins or grooves). The surface may etched to produce the desired feature on the surface of the optical flat. | 02-24-2011 |
| 20110036775 | SEA WATER REVERSE OSMOSIS SYSTEM TO REDUCE CONCENTRATE VOLUME PRIOR TO DISPOSAL - The present invention includes systems and methods for treatment of seawater RO system for recovering most of the water (i.e., 85-90%) from the concentrate of a brackish groundwater reverse osmosis treatment system that may use, e.g., a batch method. With proper pH control and antiscalant dosage, the batch-treatment SWRO system of the present invention can be used to recovery water from silica-saturated RO concentrate without fouling the membranes. Silica concentrations of over 1000 mg/L are attainable with relatively minimal pre-treatment of the silica-saturated feed solution. | 02-17-2011 |
| 20110034855 | NONINVASIVE THERAPIES IN THE ABSENCE OR PRESENCE OF EXOGENOUS PARTICULATE AGENTS - Methods are disclosed for treating cell components, cells, organelles, organs, and/or tissues with acoustic energy, electromagnetic energy, static or alternating electric fields, and/or static or alternating magnetic fields in the presence or absence of exogenous particulate agents for therapeutic applications. | 02-10-2011 |
| 20110033142 | HYBRID AIR FOIL BEARING AND METHOD OF MANUFACTURE - An air foil bearing includes a top foil, one or more orifice tubes and two or more bump foil strips disposed within a housing. The top foil is forms a substantially circular shape having one or more sets of top foil orifice holes. Each set of top foil orifice holes has at least three top foil orifice holes along a circumference of the top foil. An orifice tube is provided for each set of top foil orifice holes. The orifice tube includes a flat side having a set of tube orifice holes connected to an outer surface of the top foil. The bump foil strip is attached to the outer surface of the top foil adjacent to each side of each orifice tube. Another embodiment uses a housing with an inner surface having a curved polygonal cross-sectional shape with an odd number of curved sides. | 02-10-2011 |
| 20110030770 | NANOSTRUCTURED ORGANIC SOLAR CELLS - Solar cells having at least one N-type material layer and at least one P-type material layer forming a patterned p-n junction are described. A conducting layer may provide electrical communication between the p-n junction and an electrode layer. | 02-10-2011 |
| 20110017098 | REMOVAL AND RECOVERY OF DYE WASTE FROM EFFLUENTS USING CLAY - The present invention describes the use of clay (palygorskite) to concurrently remove indigo dye and salts from the wastewater and subsequent conversion of recovery by-products into Maya blue, an organic-inorganic hybrid pigment with applications in the paint and coating industry. The present invention provides an attractive alternative to discharging the untreated effluent into municipal treatment plants or the environment through the production of a secondary commercial product from waste stream through a by-product synergy process. | 01-27-2011 |
| 20110009701 | OCT USING SPECTRALLY RESOLVED BANDWIDTH - The embodiments disclosed herein is related to a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may be comprised and encompass spatial, angle, spectral and polarization domains. More specifically, the embodiments disclosed herein is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically. The multichannel optical coherence tomographic methods can be incorporated into an endoscopic probe for imaging a patient. The endoscope comprises an optical fiber array and can comprise a plurality of optical fibers adapted to be disposed in the patient. The optical fiber array transmits the light from the light source into the patient, and transmits the light reflected by the patient out of the patient. The plurality of optical fibers in the array is in optical communication with the light source. The multichannel optical coherence tomography system comprises a detector for receiving the light from the array and analyzing the light. The methods and apparatus may be applied for imaging a vessel, biliary, GU and/or GI tract of a patient. | 01-13-2011 |
| 20110008919 | Electronic Textiles with Electronic Devices on Ribbons - Ribbons containing e.g. inorganic NMOS devices are assembled in electrical contact with ribbons containing e.g. PMOS devices (preferably organic) to enable flexible electronic textile circuits to be inexpensive and practical for a wide variety of functions. The use of ribbons provides flexibility, reduces costs, and allows testing during assembly and different processes to be efficiently used for different components. This is apparently the first time that ribbons (especially inorganic-device-containing ribbons) have been interconnected to form a flexible CMOS electronic textile. | 01-13-2011 |
| 20110008442 | Dendritic Macroporous Hydrogels Prepared by Crystal Templating - The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel. | 01-13-2011 |
| 20110008368 | METHODS OF MODULATING THE OX40 RECEPTOR TO TREAT CANCER - Numerous disease states, such as human allergic, autoimmune, and autoimmune diseases, and cancer, may be treated by targeting OX40/OX4OL. OX4OL inhibits the generation of Tr1 cells from naïve and memory CD4+ T cells. This unique function of OX4OL is not shared by two other costimulatory TNF-family members, GITR-ligand and 4-1BB-ligand. It has been shown that signaling the OX40-receptor on human T cells by antibodies, small molecules, or the OX4OL modulates the generation and function of IL-10 producing Foxp3 | 01-13-2011 |
| 20110005589 | ASPHALTENE BASED PHOTOVOLTAIC DEVICES - Photovoltaic devices and methods of making the same, are disclosed herein. The cell comprises: a first electrically conductive layer; at least one photoelectrochemical layer comprising metal-oxide particles, an electrolyte solution, an asphaltene dye, and a second electrically conductive layer. | 01-13-2011 |
| 20110003345 | Production and Secretion of Glucose in Photosynthetic Prokaryotes (Cyanobacteria) - The present invention includes compositions and methods for making and using an isolated cyanobacterium that includes a portion of an exogenous bacterial cellulose operon sufficient to express bacterial cellulose, whereby the cyanobacterium produces extracellular glucose. The compositions and methods of the present invention may be used as a new global crop for the manufacture of cellulose, CO | 01-06-2011 |
| 20110002874 | Polymer Network Compositions and Associated Methods - Biomimetic polymer networks comprising a heteropolymer network having a cavity, the cavity having a selective affinity for a moiety, methods for making biomimetic polymer networks, and methods for using biomimetic polymer networks. | 01-06-2011 |
| 20100325072 | SYSTEM AND METHOD FOR SOLVING MULTIOBJECTIVE OPTIMIZATION PROBLEMS - A system and method for solving a set of optimization problems initializes a current region of optimal solutions for the set of optimization problems, performs a reduction phase, and provides the optimal solutions within the current region. The reduction phase creates a random sample of points within the current region and identifies a subregion of the current region that very likely does not contain any optimal solutions. The identified subregion is then removed from the current region. If the current region does not satisfies one or more convergence criteria, the process loops back to create another random sample of points and repeats the above-described steps. If, however, the current region does satisfy the convergence criteria, the optimal solutions within the current region are provided to the output device. | 12-23-2010 |
| 20100324363 | DISPOSABLE SHEATH DESIGNS FOR THE STIMULATING ENDOSCOPE AND NEEDLE ENDOSCOPES HAVING DISTAL ELECTRODES FOR NERVE BLOCK UNDER DIRECT VISION AND METHODS FOR MAKING AND USING SAME - A nerve blocking endoscope apparatus is disclosed having a disposable sheath and a stimulating assembly including an internal electrode and an external electrode for stimulation of a nerve for identification purposes and to methods for making and using same. A needle nerve blocking endoscope apparatus having an internal electrode for nerve stimulation. | 12-23-2010 |
| 20100320978 | SYSTEM, METHOD AND APPARATUS FOR CONTROLLING CONVERTERS USING INPUT-OUTPUT LINEARIZATION - A system, method and apparatus for controlling boost and buck-boost converters using input-output linearization and leading-edge modulation is provided. The controller includes a summing circuit connected to the converter to create a third voltage representing a difference between the first voltage and the second voltage. A gain circuit is connected to the summing circuit to adjust the third voltage by an appropriate gain. A modulating circuit is connected to the gain circuit, the converter, the first voltage, the second voltage and the second current to create a control signal based on the first voltage, the second voltage, the adjusted third voltage, the fourth voltage and the first current. The control signal is used to control the converter. Typically, the first voltage is a converter output voltage, the second voltage is a reference voltage, the fourth voltage is a converter input voltage, and first current is a converter inductor current. | 12-23-2010 |
| 20100319920 | METHODS FOR IMPROVING THE PRODUCTIVITY OF OIL PRODUCING WELLS - Methods for treating formations bearing brine and at least one of black oil or volatile oil using a composition containing a nonionic polymer and solvent. The solvent at least one of solubilizes or displaces at least one of brine or oil in the formation. Methods for making a composition for treating a formation bearing brine an at least one of black oil or volatile oil are also disclosed. | 12-23-2010 |
| 20100317570 | Composition and Method for the Treatment of Diseases Affected by a Peptide Receptor - The present invention includes peptidomimetic compound compositions and methods of making and using peptidomimetic compounds to modulate the activity of a peptide receptor for the treatment of one or more of hyperglycemia, insulin resistance, hyperinsulinemia, obesity, hyperlipidemia, hyperlipoproteinemia or other symptoms that relate to the function of the targeted receptor. The peptidomimetic includes an oligo-benzamide compound having at least three optionally substituted benzamides. | 12-16-2010 |
| 20100317534 | GLOBAL GERM LINE AND TUMOR MICROSATELLITE PATTERNS ARE CANCER BIOMARKERS - The present invention includes a method of identifying an increase in microsatellite DNA from a genomic nucleic acid sample comprising: obtaining a microsatellite profile from a sample suspected of comprising cancer cells; comparing the microsatellite profile to a reference microsatellite profile from a reference genome; and determining in increase in the number of microsatellite DNAs from the sample as compared to the reference genome, wherein an increase in microsatellite DNA indicates a pre-disposition to cancer and the microsatellites are upstream from the estrogen receptor-related gamma gene (ESRRG). | 12-16-2010 |
| 20100314286 | SYNTHESIS OF ACIDIC SILICA TO UPGRADE HEAVY FEEDS - A method and a product made by treating a sulfur-containing hydrocarbon heavy feed, e.g., heavy crude asphaltene reduction is disclosed herein. The method comprises the steps of: mixing the sulfur-containing hydrocarbon heavy feed with a hydrogen donor solvent and an acidified silica to form a mixture and oxidizing the sulfur in the mixture at a temperature between 50° C. and 210° C., wherein the oxidation lowers the amount sulfur in the sulfur-containing hydrocarbon heavy feed by at least 90%. | 12-16-2010 |
| 20100306993 | Method and Apparatus for Detethering Mesoscale, Microscale, and Nanoscale Components and Devices - A method and apparatus for fabricating one or more electronic devices from wafer, die or other holder including designing a plurality of electronic devices ( | 12-09-2010 |
| 20100305291 | Non-Fouling Receptor Labeled Multi-Functional Surfaces - The present invention provides compositions and methods of forming a multifunctional polymer film by plasma discharge by providing one or more monomers to a plasma discharge reactor, wherein the one or more monomers comprising one or more functional groups; polymerizing the one or more monomers into a multifunctional polymer; and forming a polymer film from the multifunctional polymer on a surface. | 12-02-2010 |
| 20100304993 | BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER - The present invention provides methods and compositions for detecting early stage ovarian cancer in a patient. Also, methods for evaluating the ovarian cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biomarkers in biological samples. | 12-02-2010 |
| 20100303877 | Controlled Release Hydrogel Films - The present invention provides hydrogels and methods of making hydrogels with precisely controlled levels of chemical compositions by mixing one or more monomers in a plasma reactor; polymerizing the one or more monomers into a polymer; crosslinking the polymer to form a hydrogel; immersing the hydrogel in a first solution; and adsorbing one or more solute species from the solution, wherein the one or more solute species are released at controlled rates. | 12-02-2010 |
| 20100298716 | METHODS AND COMPOSITIONS TO REDUCE SCATTERING OF LIGHT DURING THERAPEUTIC AND DIAGNOSTIC IMAGING PROCEDURES - Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues. | 11-25-2010 |
| 20100298376 | USE OF NOVEL NEUROPROTECTIVE 3-SUBSTITUTED INDOLONE COMPOSITIONS - The present invention provides compositions and methods of synthesizing optionally substituted 3-substituted indolin-2-ones and methods to employ the resultant compounds to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such as ischemic stroke. | 11-25-2010 |
| 20100297251 | ENCAPSULATED PARTICLES FOR ENTERIC RELEASE - The present invention provides a system for delivery of an enteric coated active agent generally resistant to disintegration in an neutral environment having one or more active agents encapsulated by a polymer coating formed by chemical vapor deposition of one or more monomers on the one or more active agents to form a chemical vapor deposition polymer coating that controls the release of the one or more active agents in the gastrointestinal tract. | 11-25-2010 |
| 20100297248 | ENCAPSULATED PARTICLES FOR AMORPHOUS STABILITY ENHANCEMENT - The present invention provides compositions and methods of making and encapsulating one or more active agents in a chemical vapor deposition layer to enhance the stability. | 11-25-2010 |
| 20100292110 | USE OF FLUOROCARBON SURFACTANTS TO IMPROVE THE PRODUCTIVITY OF GAS AND GAS CONDENSATE WELLS - The present invention includes composition having a nonionic, fluorinated polymeric surfactant, water and solvent. Embodiments of compositions according to the present invention are useful, for example, for recovering hydrocarbons from subterranean clastic formations. | 11-18-2010 |
| 20100291606 | SCREENING SYSTEM FOR DETECTING INHIBITORS OF HIV INTEGRASE-LEDGF/p-75 INTERACTION - The development and validation of a cell-based, homogeneous high throughput screening (HTS) assay for small compounds inhibiting the HIV integrase-LEDGF/p75 interaction is described herein. The HTS strategy has the potential to identify small-molecules interfering with the interaction of HIV integrase-LEDGF/p75. These small molecules represent starting scaffolds for therapeutic drug development. | 11-18-2010 |
| 20100291401 | RETICULATED MESH ARRAYS AND DISSIMILAR ARRAY MONOLITHS BY ADDITIVE LAYERED MANUFACTURING USING ELECTRON AND LASER BEAM MELTING - Compositions and methods for making a three dimensional structure comprising: designing a three-dimensional structure; melting the three-dimensional structure from two or more layers of a metal powder with a high energy electron or laser beam is described herein. The position where the metal is melted into the structure is formed along a layer of metal powder, wherein the location and intensity of the beam that strikes the metal layer is based on the three-dimensional structure and is controlled and directed by a processor. The instant invention comprises a novel dry state sonication step for removing metal powder that is not melted from the three dimensional structure. | 11-18-2010 |
| 20100291068 | NUCLEIC ACID MOLECULES AND PROTEINS FOR THE IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF OVARIAN CANCER - The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided. | 11-18-2010 |
| 20100286674 | SYSTEMS, DEVICES AND METHODS FOR IMAGING AND SURGERY - Provided herein are devices, systems and methods for imaging of biological tissue. Also provided are devices, systems and methods for surgical manipulation of biological tissue. Further provided are devices, systems and methods for combined imaging and surgical manipulation of biological tissue. | 11-11-2010 |
| 20100280846 | PHARMACEUTICAL TREATMENT EFFECTIVENESS ANALYSIS COMPUTER SYSTEM AND METHODS - Computer-implemented systems, program code, and related methods are provided. The systems, program code, and methods can be employed to analyze the effectiveness of pharmaceutical treatments for medical conditions utilizing real time prescription compliance records. Information related to medical history of a patient can be reviewed while simultaneously reviewing prescription compliance records for the same patient. Trends in target and non-target medical parameters can be identified and correlated with the prescription compliance records to determine the effectiveness of a pharmaceutical treatment on target and non-target medical parameters that various compliance and prescription levels. | 11-04-2010 |
| 20100270019 | METHOD OF OBTAINING A TREATMENT COMPOSITION FOR IMPROVING THE PRODUCTIVITY OF HYDROCARBON PRODUCING WELLS - A method of obtaining a treatment composition for treating a hydrocarbon-bearing clastic formation having brine therein to enhance recovery of hydrocarbon from the formation. The method comprises: obtaining a formation information set comprising a temperature value, brine content value, and brine composition data obtained from a geological zone of the hydrocarbon-bearing clastic formation; comparing the formation information set to a compatibility information set to generate a comparison information set, the compatibility information set comprising compatibility information for at least at least one model brine and at least one model composition at least one model temperature; selecting a treatment composition based, at least in part, on the at least one comparison information set, wherein the treatment composition comprises a second surfactant dissolved in a second solvent; and obtaining the treatment composition for treating the hydrocarbon-bearing clastic formation to enhance recovery of hydrocarbon from the formation. | 10-28-2010 |
| 20100261918 | Novel Process for Separating Lipids From a Biomass - A novel low cost separation process for separating lipid oil from an algal biomass for biofuel production is described herein. The process of the present invention comprises of two steps: (i) breaking the algae cells and (ii) separation of the lipid oils from the broken cells. The separated lipids are extracted by conventional techniques followed by conversion to a biofuel. | 10-14-2010 |
| 20100261281 | ANALYTICAL TECHNIQUE FOR MEASURING BOUND GLYCERIDES IN A BIODIESEL COMPOSITION - A method of estimating the amount of unreacted starting materials (glycerides, methyl esters, etc.) and the composition of a biodiesel using TLC in conjunction with a lipophilic dye, Nile Red is described herein. The dye based TLC method of the present invention is convenient and provides significant advantages over existing methods for estimating the purity of a biodiesel composition. | 10-14-2010 |
| 20100259745 | METHOD FOR OBTAINING FORCE COMBINATIONS FOR TEMPLATE DEFORMATION USING NULLSPACE AND METHODS OPTIMIZATION TECHNIQUES - The present invention is directed towards a method for determining deformation parameters that a patterned device would undergo to minimize dimensional variations between a recorded pattern thereon and a reference pattern, the method including, inter alia, comparing spatial variation between features of the recorded pattern with respect to corresponding features of the reference pattern; and determining deformation forces to apply to the patterned device to attenuate the dimensional variations, with the forces having predetermined constraints, wherein a summation of a magnitude of the forces is substantially zero and a summation of moment of the forces is substantially zero. | 10-14-2010 |
| 20100254897 | Seeds and Markers for Use in Imaging - A contrast marker having a casing and a novel MRI contrast agent comprising metal complexes disposed around, within, or abuting the casing is provided. Such contrast markers may be placed in a strand, with or without a therapy seed, to produce a seeded strand useful for imaging and in connection with brachytherapy. | 10-07-2010 |
| 20100250227 | DETECTING AND CORRECTING OUT-OF-ORDER STATE ACCESSES USING DATA - A method, computer program product and system for detecting that a functional model execution is out-of-order with respect to a target execution. A value of a store instruction to be stored in a memory address, where the store instruction is executed by the functional model, is received by the timing model. This value is stored by the timing model in a target oracle memory at a time when the target system would execute the store instruction. The timing model compares the value in the target oracle memory with the value of a load instruction to be loaded from the same memory address, which is received from the functional model, at a time when the target system would execute the load instruction. The timing model detects an out-of-order instruction stream with respect to the target instruction stream if there is a miscomparison. | 09-30-2010 |
| 20100249609 | MEASUREMENT OF NEURAL FUNCTIONALITY USING PHASE SENSITIVE OPTICAL COHERENCE REFLECTOMETRY - Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents. | 09-30-2010 |
| 20100247611 | TITANIUM DIOXIDE NANOTUBES FOR PRODUCTION AND DELIVERY OF NITRIC OXIDE AND METHODS FOR PRODUCTION THEREOF - The present disclosure describes compositions operable for releasing nitric oxide under photochemical conditions. The compositions include a titanium dioxide nanomaterial and a nitric oxide-releasing compound deposited on the titanium dioxide nanomaterial that is operable to release nitric oxide under photochemical conditions. Titanium dioxide nanomaterials include, for example, titanium dioxide nanotubes. To facilitate the photochemical release of nitric oxide, some embodiments of the compositions further include a semiconductor that is deposited on the titanium dioxide nanotubes. Both the semiconductor and the nitric oxide-releasing compound may be deposited on the interior surface, exterior surface, or both of the titanium dioxide nanotubes. A polymer may wrap the titanium dioxide nanotubes to protect the nitric oxide-releasing compounds from moisture. Also disclosed herein are methods for producing such compositions and medical devices obtained therefrom. | 09-30-2010 |
| 20100247569 | Influenza A Virus Vaccines and Inhibitors - The present invention includes compositions and methods related to the structure and function of the cellular polyadenylation and specificity factor 30 (CPSF30) binding site on the surface of the influenza A non-structural protein 1 (NS1). Specifically, critical biochemical reagents, conditions for crystallization and NMR analysis, assays, and general processes are described for (i) discovering, designing, and optimizing small molecule inhibitors of influenza A (avian flu) viruses and (ii) creating attenuated influenza virus strains suitable for avian and human flu vaccine development. | 09-30-2010 |
| 20100247506 | FORMATION OF STABLE SUBMICRON PEPTIDE OR PROTEIN PARTICLES BY THIN FILM FREEZING - The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets solvent such that the effective ingredient is exposed to a vapor-liquid interface of less than 50, 100, 150, 200, 250, 200, 400 or 500 cm | 09-30-2010 |
| 20100245114 | Thin Flexible Sensor - The present invention provides a sensor ( | 09-30-2010 |
| 20100240060 | Detection and Diagnosis of Smoking Related Cancers - Gene probes for specific regions of chromosome 3 (3p21.3) and chromosome 10 (10q22) have been found to be tools for the diagnosis and prognosis of smoking related cancers such as non-small cell lung cancer (NSCLC). For example, these probes can be used with fluorescence in situ hybridization (FISH), and used to stratify smokers into high and low risk groups, as well as determine a patients susceptibility to the development of smoking related cancers. | 09-23-2010 |
| 20100237258 | Systems and Methods for Altering Visual Acuity - Provided are methods, systems, and apparatus for altering a modulation transfer function of an imaging system. The described methods, systems and apparatus can be used to temporarily alter visual acuity of a subject. | 09-23-2010 |
| 20100226608 | MULTIMODE INTERFERENCE COUPLER FOR USE WITH SLOT PHOTONIC CRYSTAL WAVEGUIDES - The present invention provides an optical apparatus having a multimode interference coupler configured to optically couple a strip waveguide to a slot photonic crystal waveguide. The multimode interference coupler has a coupling efficiency to the slot photonic crystal waveguide greater than or equal to 90%, a width that is approximately equal to a defect width of the slot photonic crystal waveguide, a length that is equal to or less than 1.5 μm, and interfaces with the slot photonic crystal waveguide at an edge of a period that gives a termination parameter of approximately zero. The optical apparatus may also include an insulation gap disposed between the multimode interference coupler and the slot photonic crystal waveguide, wherein the length of the multimode interference coupler is reduced by approximately one half of a width of the insulation gap. | 09-09-2010 |
| 20100224851 | SYNTHESIZING GRAPHENE FROM METAL-CARBON SOLUTIONS USING ION IMPLANTATION - A method and semiconductor device for synthesizing graphene using ion implantation of carbon. Carbon is implanted in a metal using ion implantation. After the carbon is distributed in the metal, the metal is annealed and cooled in order to precipitate the carbon from the metal to form a layer of graphene on the surface of the metal. The metal/graphene surface is then transferred to a dielectric layer in such a manner that the graphene layer is placed on top of the dielectric layer. The metal layer is then removed. Alternatively, recessed regions are patterned and etched in a dielectric layer located on a substrate. Metal is later formed in these recessed regions. Carbon is then implanted into the metal using ion implantation. The metal may then be annealed and cooled in order to precipitate the carbon from the metal to form a layer of graphene on the metal's surface. | 09-09-2010 |
| 20100224361 | Compositions and Methods for Treating a Water Blocked Well - The present invention includes a method of treating a hydrocarbon-bearing clastic formation having non-connate water, the method includes contacting the hydrocarbon-bearing clastic formation with a composition that includes a solvent and a surfactant wherein the solvent at least partially displaces or solubilizes the water in the formation. | 09-09-2010 |
| 20100221343 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING - The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. | 09-02-2010 |
| 20100210835 | Mimetic Drug Delivery Systems for Release with Specific Molecular Triggers - The present invention provides a molecule-imprinted reversible polymeric network composition and methods of making and using the same. In addition, the instant invention provides a composition for the delivery of an active agent. The composition includes a polymer matrix formed from at least a first and a second monomer and one or more active agents deposited within the polymer matrix. One or more recognition sites on at least one of the at least first and second monomers and an active site formed in the polymer matrix by the one or more recognition sites. The template binds to the active site by interacting with at least one of the one or more recognition sites, wherein the template causes the release of the one or more active agents. | 08-19-2010 |
| 20100207101 | INCORPORATING GATE CONTROL OVER A RESONANT TUNNELING STRUCTURE IN CMOS TO REDUCE OFF-STATE CURRENT LEAKAGE, SUPPLY VOLTAGE AND POWER CONSUMPTION - A semiconductor device and method for fabricating a semiconductor device incorporating gate control over a resonant tunneling structure. The semiconductor device includes a source terminal, a gate terminal, a drain terminal, and a resonant tunneling structure located beneath or adjacent to the gate terminal, where the gate terminal controls an electrostatic potential drop through the resonant tunneling structure as well as controlling a potential within a portion of the conduction channel immediately beneath the gate terminal as in a MOSFET. The semiconductor device is fabricated by growing epitaxial layers of tunnel barriers and quantum wells, where a quantum well is formed between each set of two tunneling barriers. Additionally, the epitaxial layers of tunnel barriers and quantum wells are grown, etched and patterned to form a resonant tunneling structure. Further, the semiconductor device is grown, etched and patterned to form a gate, source and drain electrode. | 08-19-2010 |
| 20100204125 | GENETIC ALTERATIONS ASSOCIATED WITH CANCER - The present invention provides new probes for the detection of chromosomal alterations associated with cancer, particularly ovarian cancer. The probes bind selectively with target nucleic acid sequences at 3q26. | 08-12-2010 |
| 20100198421 | Methods and Apparatus for Design and Control of Multi-port Power Electronic Interface for Renewable Energy Sources - Methods and systems for energy management are disclosed. An example system includes a first port connected to an energy storage device for bidirectional flow of energy, a second port connected to an energy source device for unidirectional flow of energy, a third port connected to a utility grid for bidirectional flow of energy, and a unified control system with control logic configured to simultaneously control energy flow between the first, second, and third ports based on at least two factors from the group consisting of: a state of charge of the energy storage device, a state of the energy source device, and a state of the utility grid. Other embodiments are described and claimed. | 08-05-2010 |
| 20100198080 | Optical Methods to Intraoperatively Detect Positive Prostate and Kidney Cancer Margins - The present invention includes using optical spectroscopy as an innovative technique for ex-vivo demonstration of renal and prostate tumors. The apparatus and methods disclosed herein demonstrate the ability of optical spectroscopy to reliably differentiate tumor from normal tissue in renal specimens. | 08-05-2010 |
| 20100197031 | FUNCTIONALIZED EXPANDED PORPHYRINS - Disclosed are functionalized expanded porphyrins that can be used as spectrometric sensors for high-valent actinide cations. The disclosed functionalized expanded porphyrins have the advantage over unfunctionalized systems in that they can be immobilized via covalent attachment to a solid support comprising an inorganic or organic polymer or other common substrates. Substrates comprising the disclosed functionalized expanded porphyrins are also disclosed. Further, disclosed are methods of making the disclosed compounds (immobilized and free), methods of using them as sensors to detect high valent actinides, devices that comprise the disclosed compounds, and kits. | 08-05-2010 |
| 20100190176 | TUMOR SUPPRESSOR DESIGNATED TS10Q23.3 - A specific region of chromosome 10 (10q23.3) has been implicated by series of studies to contain a tumor suppressor gene involved in gliomas, as well as a number of other human cancers. One gene within this region was identified, and the corresponding coding region of the gene represents a novel 47 kD protein. A domain of this product has an exact match to the conserved catalytic domain of protein tyrosine phosphatases, indicating a possible functional role in phosphorylation events. Sequence analyses demonstrated the a number of exons of the gene were deleted in tumor cell lines used to define the 10q23.3 region, leading to the classification of this gene as a tumor suppressor. Further analyses have demonstrated the presence of a number of mutations in the gene in both glioma and prostate carcinoma cells. Methods for diagnosing and treating cancers related to this tumor suppressor, designated as TS10q23.3, also are disclosed. | 07-29-2010 |
| 20100189718 | MOLECULES WITH EXTENDED HALF-LIVES, COMPOSITIONS AND USES THEREOF - The present invention provides molecules, including IgGs, non-IgG immunoglobulins, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. | 07-29-2010 |
| 20100188558 | Automatic Focusing Apparatus and Method for Digital Images Using Automatic Filter Switching - An apparatus and method for automatically focusing a lens of a digital imaging device, such as a digital still or video camera or camera phone, that reduces the auto focus time while not compromising image sharpness quality and simultaneously reducing device power consumption due to focus actuator movement, all without tuning or adjustment of thresholds or parameters is disclosed. The present invention automatically computes a set of digital band-pass filters matched to the imaging device specifications along with corresponding step-size magnitudes. A filter-switching search for the in-focus focus actuator position is formulated such that filters are switched and step-sizes are reduced as the search gets closer to the in-focus position by utilizing local estimates of the first and second-order differential information of the focus value surface. | 07-29-2010 |
| 20100185660 | DETERMINING SUITABILITY OF ENTITY TO PROVIDE PRODUCTS OR SERVICES BASED ON FACTORS OF ACQUISITION CONTEXT - A method, system and computer program product for determining the suitability of an entity to provide products or services. Category and measurement data is received concerning the entity where each category is assigned a value based on the acquisition context. If the value assigned to a category exceeds a threshold, then the measurement data for that category is used in evaluating the entity. This measurement data is weighted according to the acquisition context. A binary value is generated for each weighted measurement value that exceeds a threshold. These binary values are summed and weighted according to the confidence that the source of the data is correct. Further, the past performance and reputation of the entity is used in applying a weight to the summed binary values to generate a suitability value. If the suitability value exceeds a threshold, then it is deemed suitable to conduct business with the entity. | 07-22-2010 |
| 20100183925 | Cation-Substituted Spinel Oxide and Oxyfluoride Cathodes for Lithium Ion Batteries - The present invention includes compositions and methods of making cation-substituted and fluorine-substituted spinel cathode compositions by firing a LiMn | 07-22-2010 |
| 20100183721 | ENHANCED DELIVERY OF IMMUNOSUPPRESSIVE DRUG COMPOSITIONS FOR PULMONARY DELIVERY - The present invention includes compositions and methods for making and using a rapid dissolving, high potency, substantially amorphous nanostructured aggregate for pulmonary delivery of tacrolimus and a stabilizer matrix comprising, optionally, a polymeric or non-polymeric surfactant, a polymeric or non-polymeric saccharide or both, wherein the aggregate comprises a surface area greater than 5 m | 07-22-2010 |
| 20100183702 | Therapies For Cancer Using RLIP76 - The present invention is a composition identified as a region of ralA binding protein 1, wherein the region neighbors a membrane-associated portion of the ralA binding protein 1, reduces transport activity and membrane association of the ralA binding protein 1 and kills cells undergoing uncontrolled cell growth in a subject that has cells undergoing uncontrolled cell growth. The region is used to generate medicines that kill malignant cells and tumorigenic cells. Medicines may be in the form of antibodies, si-RNA and small molecules that recognize the region. | 07-22-2010 |
| 20100181655 | ESTABLISHING A UNIFORMLY THIN DIELECTRIC LAYER ON GRAPHENE IN A SEMICONDUCTOR DEVICE WITHOUT AFFECTING THE PROPERTIES OF GRAPHENE - A method and semiconductor device for forming a uniformly thin dielectric layer on graphene. A metal or semiconductor layer is deposited on graphene which is located on the surface of a dielectric layer or on the surface of a substrate. The metal or semiconductor layer may act as a nucleation layer for graphene. The metal or semiconductor layer may be subjected to an oxidation process. A thin dielectric layer may then be formed on the graphene layer after the metal or semiconductor layer is oxidized. As a result of synthesizing a metal-oxide layer on graphene, which acts as a nucleation layer for the gate dielectric and buffer to graphene, a uniformly thin dielectric layer may be established on graphene without affecting the underlying characteristics of graphene. | 07-22-2010 |
| 20100181068 | Method and System for Treating Hydrocarbon Formations - The present invention includes compositions and methods for treating a hydrocarbon-bearing formation having brine and at least one temperature, wherein the brine has at least one first composition by obtaining first compatibility information for a first model brine and a first treatment composition at a model temperature, wherein the first model brine has a composition selected at least partially based on the first brine composition, wherein the model temperature is selected at least partially based on the formation temperature, and wherein the first treatment composition comprises at least one first surfactant and at least one first solvent; based at least partially on the first compatibility information, selecting a treatment method for the hydrocarbon-bearing formation, and treating the hydrocarbon-bearing formation with the selected treatment method. | 07-22-2010 |
| 20100173033 | Device for Holding a Template for Use in Imprint Lithography - An imprint lithography template may be used to form an imprinted layer in a light curable liquid disposed on a substrate. During use, the template may be disposed within a template holder. The template holder may include a body with an opening configured to receive the template, a support plate, and an actuator system coupled to the body. The actuator system may be configured to alter a physical dimension of the template during use. | 07-08-2010 |
| 20100168587 | CATHETER IMAGING PROBE AND METHOD - A catheter imaging probe for a patient. The probe includes a conduit through with energy is transmitted. The probe includes a first portion through which the conduit extends. The probe includes a second portion which rotates relative to the conduit to redirect the energy from the conduit. A method for imaging a patient. The method includes the steps of inserting a catheter into the patient. There is the step of rotating a second portion of the catheter relative to a conduit extending through a first portion of the catheter, which redirects the energy transmitted through the conduit to the patient and receives the energy reflected back to the second portion from the patient and redirects the reflected energy to the conduit. | 07-01-2010 |
| 20100167964 | Compositions and Methods for Treating a Water Blocked Well - The present invention includes a method of treating a hydrocarbon-bearing clastic formation having non-connate water by contacting the hydrocarbon-bearing clastic formation with a composition that includes a solvent and a nonionic fluorinated polymeric surfactant wherein the solvent at least partially displaces or solubilizes the water in the formation. | 07-01-2010 |
| 20100167177 | Carbon nanofiber with skin-core structure, method of producing the same, and products comprising the same - This invention relates to carbon nanofiber having a skin-core structure containing pitch and polyacrylonitrile, to a method of producing the carbon nanofiber, and to a product including the carbon nanofiber. The carbon nanofiber includes polyacrylonitrile and pitch having different properties respectively constituting a skin layer and/or a core layer, with a diameter of 1 μm or less, and thus functions of the carbon nanofiber vary depending on change in composition thereof. | 07-01-2010 |
| 20100160994 | CARDIOVASCULAR POWER SOURCE FOR AUTOMATIC IMPLANTABLE CARDIOVERTER DEFIBRILLATORS - Aspects according to the present invention provide a method and implant suitable for implantation inside a human body that includes a power consuming means responsive to a physiological requirement of the human body, a power source and a power storage device. The power source comprises a sheathed piezoelectric assembly that is configured to generate an electrical current when flexed by the tissue of the body and communicate the generated current to the power storage device, which is electrically coupled to the power source and to the power consuming means. | 06-24-2010 |
| 20100160791 | PORCINE BILIARY TRACT IMAGING - The present invention includes apparatus and method to prevent surgical injury. The invention incorporates near infrared (NIR) spectroscopy, which capitalizes on near infrared light's ability to penetrate deeply into tissues and spectroscopic capability to discern tissue's chemical properties. The present invention further characterized the NIR optical properties of bile containing structures as a clinically useful probe. | 06-24-2010 |
| 20100154993 | SEPARATION METHODS FOR IMPRINT LITHOGRAPHY - Methods for separating a template from a substrate are described. Generally, the template and the substrate have a template-substrate interface. A tilting motion may be generated about a tilting axis located at the template-substrate interface. The tilting motion may include forming a wedge between the template and the substrate at one end of the template-substrate interface. The substrate may be titled with respect to the template, and the template may remain stationary. Additionally, a force may be applied to increase a distance between the template and the substrate, such that the template is spaced apart from the substrate. | 06-24-2010 |
| 20100152071 | Method for Treating a Formation with a Solvent - The present invention includes compositions and methods for treating a hydrocarbon-bearing formation by contacting the hydrocarbon-bearing formation with a fluid that includes at least one of a polyol or polyol ether, wherein the polyol and polyol ether independently have from 2 to 25 carbon atoms; and at least one of a monohydroxy alcohol, ether, or ketone, wherein the monohydroxy alcohol, ether, and ketone independently have from 1 to 4 carbon atoms, and wherein the at least one of a polyol or polyol ether is present in the fluid at at least 50 weight percent, based on the total weight of the fluid. | 06-17-2010 |
| 20100148126 | GENOMIC SEQUENCING USING MODIFIED PROTEIN PORES AND IONIC LIQUIDS - The present invention is a nanopore stochastic sensing system comprising modified protein pores for detection and sequencing of oligonucleotides. The system comprises a genetically modified protein pore with a variety of non-covalent bonding recognition sites to significantly slow down the translocation of ssDNA in the pores. The present invention also describes identification and application of DNA fingerprints, which are a sequence of small current modulation events for the determination of the sequence of ssDNA molecules. In separate embodiments the present invention describes a system and a method for the detection of monovalent cations, liquid explosives, water-insoluble compounds, biomolecules and oligonucleotides. The system comprising a wild-type or genetically modified protein pore with or without a molecular adaptor. Analyte samples and mixtures are added along with specially synthesized ionic liquids. | 06-17-2010 |
| 20100144743 | COMPOSITIONS AND METHODS FOR INHIBITION OF TYROSINE KINASES - Compositions for inhibiting the catalytic activity of tyrosine kinases comprising compounds represented by Formulas (I), (II), and (III). Methods for treating proliferative diseases comprising administering a therapeutically effective amount of the above compositions. | 06-10-2010 |
| 20100144333 | SYSTEM, METHOD AND APPARATUS FOR PROVIDING COMMUNICATIONS THAT CONFORM TO A CELLULAR COMMUNICATION STANDARD AND A NON-CELLULAR COMMUNICATION STANDARD - The present invention provides a software defined radio transceiver that includes a programmable cellular radio front end and a programmable baseband processor. The programmable cellular radio front end is typically a digital radio frequency processor configured to support a cellular communication standard. The programmable baseband processor is connected to the digital radio frequency processor. The programmable baseband processor (a) selectively reconfigures the cellular configured digital radio frequency processor to support a non-cellular communication standard by bypassing one or more cellular communication standard specific function, and modifying one or more operating parameters to conform to the non-cellular communication standard, (b) processes input data in accordance with the non-cellular communication standard and provides the processed input data to the digital radio frequency processor for transmission, and (c) receives output data from the digital radio frequency processor and processes the received output data to obtain transmitted data. | 06-10-2010 |
| 20100137562 | MAVS IN THE PREVENTION AND TREATMENT OF VIRAL DISEASE - The present invention includes compositions and methods for the identification, characterization and use of a novel anti-viral protein that includes a mitochondrial anti-viral signaling protein. | 06-03-2010 |
| 20100137169 | Method for Treating a Fractured Formation - The present invention includes compositions and methods of treating a hydrocarbon-bearing formation, the formation having at least one fracture, by contacting the fracture with a composition that includes a solvent and a nonionic fluorinated polymeric surfactant, wherein the composition interacts with at least a portion of the proppants in the fracture. | 06-03-2010 |
| 20100134276 | Location and Tracking System, Method and Device Using Wireless Technology - A system, method, and devices for locating an object, in which the system includes objects having location tags for projecting data about the object, a processing unit for receiving data about the object, and an algorithm for processing the data. Typically, the location tag includes at least one mobility sensor that projects sensory data about the object, a wireless transceiver that projects received signal strength indication data about the object and a microprocessor. The processing unit receiving the sensory data and the received signal strength indication data about the object. The algorithm processes the data, provides a location estimate about the object and thereby locates the object. | 06-03-2010 |
| 20100130434 | Hexose Compounds to Treat Cancer - Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a hexose compound to a subject in need thereof The subject invention includes methods of treating brain and pancreatic cancer comprising the administration of a therapeutically effective amount of a mannose compound to a subject in need thereof The subject invention further includes methods of treating the proliferation of tumors comprising the administration of a therapeutically effective amount of 2-FM to a subject in need thereof. | 05-27-2010 |
| 20100129308 | Polymers Functionalized with Ion-Specific Recognition Elements - Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution. | 05-27-2010 |
| 20100126297 | Microrobots with large actuation volumes, and controllers, systems, and methods - Robots, and atomic force microscopes including robots, that utilize in-plane actuators to provide large out-of-plane working volumes and forces. | 05-27-2010 |
| 20100125098 | TREATMENT OF CANCER WITH COMPLEX ORGANIC-INORGANIC PIGMENT COMPOSITIONS - The present invention includes compositions and methods for treating disorders of the skin or mucosa resulting from cancer therapies comprising: identifying a patient receiving cancer treatment; and administering to said patient an effective dose of a treated organic/inorganic complex material with an organic dye molecule or derivative thereof, in a pharmaceutically acceptable carrier. | 05-20-2010 |
| 20100124566 | Protection against and treatment of ionizing radiation - Methods of preparing a proteoliposome comprise the step of contacting a liposome with an effective portion of RalBP1 to create a proteoliposome. RalBP1 is effective for the protection and treatment of mammals and the environment against the accumulation of toxic compounds, and prevents accumulation of one or more toxic compounds, reduces the concentration of toxic compounds, and protects against further contamination with one or more toxic compounds. In addition, RalBP1 is effective for the protection and treatment of mammals against the effects of ionizing radiation. | 05-20-2010 |
| 20100122904 | INCORPORATING CMOS INTEGRATED CIRCUITS IN THE DESIGN OF AFFINITY-BASED BIOSENSOR SYSTEMS - A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a complementary metal-oxide-semiconductor (“CMOS”) integrated circuit. The biosensor system further includes an optical filter fabricated on the CMOS integrated circuit. Additionally, a plurality of capturing probes is optically coupled to the CMOS integrated circuit. Alternatively, another type of biosensor system includes a silicon substrate. The alternative biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the alternative biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the alternative biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the alternative biosensor system includes a plurality of probes attached to the sensing electrode. | 05-20-2010 |
| 20100120251 | Large Area Patterning of Nano-Sized Shapes - Methods for creating nano-shaped patterns are described. This approach may be used to directly pattern substrates and/or create imprint lithography molds that may be subsequently used to directly replicate nano-shaped patterns into other substrates in a high throughput process. | 05-13-2010 |
| 20100120097 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING - The present invention includes novel compositions and method for nucleic acid sequencing. The methods and compositions permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number of different oligonucleotides with superior output and quality. | 05-13-2010 |
| 20100119708 | Filling structures of high aspect ratio elements for growth amplification and device fabrication - The present invention includes compositions, devices and methods for filling structures of high aspect ratio elements for growth amplification and device fabrication. A method includes a method of filling a structure comprising the steps of providing one or more structures, each structure having a plurality of high aspect ratio elements, wherein the aspect ratio is at least 5; and coating the plurality of high aspect ratio elements with at least one solidifying material produced by a form of chemical vapor deposition thereby forming a structured-film. Compositions of the present invention are solid formed structures that are less fragile, do not require such delicate handling to avoid serious degradation, are more stable, last longer, do not deform, and exhibit little stress as well as improved properties that include mechanical, chemical, electrical, biologic, and optical. | 05-13-2010 |
| 20100113932 | Rapid and Accurate Detection of Bone Quality Using Ultrasound Critical Angle Reflectometry - The present invention is an apparatus, method and system for determining the coefficient of elasticity of a target by detecting an ultracritical reflection of ultrasound waves directed at the target using an ultrasound transducer at two or more angles simultaneously and calculating the elasticity coefficient of the target. | 05-06-2010 |
| 20100112750 | Post-Processing Treatment of Conductive Polymers to Enhance Electrical Conductivity - A method for enhancing electrical conductivity of a film which includes at least one conductive polymer. The method includes providing the film comprising the at least one conductive polymer and at least one polymer acid, agitating the film in at least one reagent; and, placing the film on a heated surface. The at least one reagent includes a reagent acid that is stronger than the polymer acid. The conductivity of the treated film is significantly greater than the conductivity of the untreated film. | 05-06-2010 |
| 20100111136 | OPTICAL FIBER BASED POLYMER CORE SENSOR - An optical fiber based polymer core sensor includes an optical fiber having a core and an end having a cured polymer core affixed to the core of the optical fiber. The cured polymer core extends outward from the end of the optical fiber and has a diameter approximately equal to the core of the optical fiber. Note the cured polymer core can be substantially cylindrical, tapered or geometrically shaped. The optical fiber based polymer core sensor can be used to measure a temperature, measure a strain, measure a distance, measure a refractive index, detect or measure an analyte, detect a toxin, detect a biological agent, monitor a chemical process, or a combination thereof | 05-06-2010 |
| 20100104148 | METHOD AND APPARATUS FOR DETECTING SPICULATED MASSES IN MAMMOGRAPHY - A method and apparatus detects one or more spiculated masses in an image using a processor. The image is received in the processor. The received image is filtered using one or more Gaussian filters to detect one or more central mass regions. The received image is also filtered using one or more spiculated lesion filters to detect where the one or more spiculated masses converge. In addition, the received image is filtered using one or more Difference-of-Gaussian filters to suppress one or more linear structures. An enhanced image showing the detected spiculated masses is created by combining an output from all of the filtering steps. The enhanced image is then provided to an output of the processor. | 04-29-2010 |
| 20100102403 | METHOD AND APPARATUS FOR FABRICATING PIEZORESISTIVE POLYSILICON BY LOW-TEMPERATURE METAL INDUCED CRYSTALLIZATION - The present invention provides a method and apparatus for fabricating piezoresistive polysilicon on a substrate by low-temperature metal induced crystallization by: (1) providing the substrate having a passivation layer; (2) performing, at or near room temperature in a chamber without breaking a vacuum or near-vacuum within the chamber, the steps of: (a) creating a metal layer on the passivation layer, and (b) creating an amorphous silicon layer on the metal layer, wherein the metal layer and the amorphous silicon layer have approximately the same thickness; (3) annealing the substrate, the passivation layer, the metal layer and the amorphous silicon layer at a temperature equal to or less than 600° C. and a period of time equal to or less than three hours to form a doped polysilicon layer below a residual metal layer; and (4) removing the residual metal layer to expose the doped polysilicon layer. | 04-29-2010 |
| 20100099198 | APPARATUS AND SYSTEM FOR PATTERN RECOGNITION SENSING FOR BIOMOLECULES - The present invention is an array nanopore stochastic sensing system for detection of single biomolecules and oligonucleotides. The system comprises a multi-channel system with multiple genetically modified protein pores for detection of analytes using the pattern recognition mechanism. By monitoring current blockade patterns, identity of single biomolecules can be determined in complex mixtures. | 04-22-2010 |
| 20100094341 | NEEDLE-ELECTRODE AND TISSUE ANCHOR SYSTEM - The disclosure provides a needle-electrode anchor system having a needle and an optional electrode with one or more anchors. The system can provide an electrical cutting current to the needle-electrode to create an opening in a tissue portion. An anchor coupled to the needle-electrode can be pushed through the opening with a pusher and pulled into position to set the anchor on a distal surface of the opening. If the tissue portion is to be approximated to another tissue portion, the system can be relocated to another tissue portion and another opening created with the cutting current with another anchor pushed through the opening and secured on a distal surface. Lines coupled to the anchors can be pulled together, approximating the tissue portions. If the tissue portion is to be retracted, an anchor line can be grasped to retract the tissue portion from an adjacent tissue portion. | 04-15-2010 |
| 20100090341 | NANO-PATTERNED ACTIVE LAYERS FORMED BY NANO-IMPRINT LITHOGRAPHY - Patterned active layers formed by nano-imprint lithography for use in devices such as photovoltaic cells and hybrid solar cells. One such photovoltaic cell includes a first electrode and a first electrically conductive layer electrically coupled to the first electrode. The first conductive layer has a multiplicity of protrusions and recesses formed by a nano-imprint lithography process. A second electrically conductive layer substantially fills the recesses and covers the protrusions of the first conductive layer, and a second electrode is electrically coupled to the second conductive layer. A circuit electrically connects the first electrode and the second electrode. | 04-15-2010 |
| 20100086442 | Biosensor to Detect Infectious Agents - The present invention provides a sensor for the detection of chemical agents in real time. The sensor includes a sample region having a detector disposed about a substrate where a chemical agent binds to the detector to generate in a signal. The sensor includes a microcontroller in communication with the detector, an analog to digital converter, and a communication module to process the signal into an analytical signal. In addition, the sensor includes an antenna in communication with the microcontroller to enable a wireless communication network, wherein the analytical signal can be transmitted and a power source in operable communication with the microcontroller to supply a source of power to the sensor. | 04-08-2010 |
| 20100085563 | Illumination Sources and Customizable Spectral Profiles - Methods for generating a customized spectral profile, which can be used to generate a corresponding filter, lamp or other type of illuminant. A trial spectrum can be generated. A reference spectrum can be determined or otherwise obtained. A SOURCE spectrum can be determined or otherwise obtained. One or more optical indices can be calculated using the trial spectrum and one or more of the optical indices are optimized by varying the trial spectrum to generate the customized spectral profile. A radiation force parameter can be used to minimize unsafe build-up of light in spectral regions. Adaptations of color rendering parameters can be used in the optimization process. Smoothing parameters can be used to enable easier design of filter structures. A reflectance camera can be used to measure reflectance data at one or more pixels of a digital representation of an object to be illuminated. | 04-08-2010 |
| 20100080987 | POLYMERIC FILMS TO ENHANCE CELL GROWTH - The present invention provides a method for creating surface-tailored polymer coating for improved cells proliferation by converting one or more carbonaceous monomers each comprising one or more functional groups to a monomer vapor; contacting the monomer vapor and a substrate; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored polymer coating on the substrate at a thicknesses of between 25 and 300 nm and has a functional group surface density of between 3 and 9%, wherein the surface-tailored polymer coating enhances cell proliferation. | 04-01-2010 |
| 20100075325 | COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF BREAST CANCER - The invention relates to nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided. | 03-25-2010 |
| 20100068724 | Biomaker for ovarian and endometrial cancer: hepcidin - The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry. | 03-18-2010 |
| 20100059433 | POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE - The present invention describes methods and compositions for the reduction, prevention and elimination of biofilm formation on a surface. The present invention provides a method of depositing a coating material to reduce or prevent biofilm formation on a surface by adding a dopamine coating material to a liquid solvent to form a solution mixture, adjusting a pH of the solution mixture to 8, 9, or 10 and dissolving the dopamine coating material in the liquid solvent. The solution mixture is then placed into contact with one or more surfaces to form a dopamine coating on the surface to reduce biofilm formation. | 03-11-2010 |
