| Board of Governors for Higher Education, State of Rhode Island and Providence Plantations Patent applications |
| Patent application number | Title | Published |
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| 20110316189 | SELF-MENDING COMPOSITES INCORPORATING ENCAPSULATED MENDING AGENTS - A cement mixture is disclosed that includes an aqueous mending agent that is disbursed within but isolated from the cement mixture, wherein the aqueous mending agent will form molecular bonds with hardened cement that is formed by the cement mixture when the mending agent is permitted to flow within the hardened cement. | 12-29-2011 |
| 20110281369 | ANALYSIS OF MYCOPHENOLIC ACID IN SALIVA USING LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY - A method for mass spectrometric analysis of a saliva sample possibly containing mycophenolic acid or its metabolites mycophenolic acid phenyl glucuronide (MPAG) or mycophenolic acid acyl-glucuronide (Acyl-MPAG), including the steps: (a) providing a saliva sample containing one or more drug or metabolites; (b) deproteinating the sample; (c) separating the one or more drug or metabolites from the saliva sample; and (d) analyzing the one or more drug or metabolites using a mass spectrometer. The sample containing one or more MPA or metabolites is obtained from in an oral fluid based biological samples i.e. whole saliva or saliva obtained by chemical or mechanical stimulation or from specific salivary glands. The size of the sample contains one or more MPA or metabolites is at least about 100 microL. A kit for use in mass spectrometric analysis of a sample may contain one or more MPA or metabolites from saliva samples, comprising: (a) reagents for deproteinating of the saliva sample, including internal standards; (b) reagents for separating the one or more MPA or metabolites from the saliva sample; (c) reagents for analyzing the one or MPA or metabolites using a mass spectrometer; (d) a solution of one or more MPA or metabolites in saliva samples; and (e) instructions for analyzing the one or more MPA or saliva using a mass spectrometer. The kit includes (a) mobile phase solutions; (b) a chromatography column; and (c) a quality control specimen. | 11-17-2011 |
| 20110264635 | SYSTEMS AND METHODS FOR PROVIDING CONTINUOUS FILE PROTECTION AT BLOCK LEVEL - A system and method are disclosed for providing continuous file protection in a computer processing system. In accordance with an embodiment, the system includes a configuration module, a filter driver, and a storage module. The configuration module permits a user to elect certain files or folders for protection. The configuration module runs at an application layer without involving the computer processing system's operating system. The filter driver intercepts and splits write input and outputs addressed at protected files or folders. The storage module is also run without involving the computer processing system's operating system. The storage module is for performing functions including data logging, version managements, and data recovery. | 10-27-2011 |
| 20110034670 | BISUBSTRATE INHIBITORS OF PROTEIN KINASES AS THERAPEUTIC AGENTS - A bisubstrate inhibitor of Src kinases, having a nucleotide or N-heteroaromatic moiety; and a peptide/phosphopeptide, peptidomimetic, or phosphopeptide mimic moiety. The moieties are linked by a rigid or a flexible linker. The nucleotide or N-heteroaromatic moiety is ATP, ATP-mimics, N-heteroaromatics including purine-based derivatives, pyrimidine-based derivatives such as 2,4-diamino-5-substituted pyrimidine derivatives, pyrazole[3,4-d]pyrimidine derivatives, pyrrolo[2,3-d]pyrimidine derivatives, pyrido[2,3-d]pyrimidine derivatives, amino-substituted dihydropyrimido[4,5-d]pyrimidinone derivatives, thieno- and furo-substituted derivatives, quinazoline derivatives, and quinoline derivatives, and several natural products such as aminogenistein. The phosphopeptide mimics comprise phosphonate-based phosphotyrosine mimetics such as phosphonomethylphenylalanine (Pmp) and its analogues, carboxylic acid-based phosphotyrosine mimetics such as malonyltyrosine or phenylalanine analogues and their derivatives such as carboxymethyl phenylalanine, uncharged pTyr mimetics, and conformationally constrained peptides. The phosphopeptide or phosphopeptide mimics inhibits the Src kinases SH2 domain. | 02-10-2011 |
| 20100148758 | SYSTEMS AND METHODS FOR ON-CHIP POWER MANAGEMENT - A power measurement system is disclosed for use on an integrated circuit for measuring the power used by the integrated circuit. The power measurement system includes a low-dropout voltage regulator and a signal input unit. The low-dropout voltage regulator includes a power transistor that couples a supply voltage to a circuit to be powered by the supply voltage, and the low-dropout voltage regulator provides an internal adjustment signal (V | 06-17-2010 |
| 20100116379 | COMPOSITE USED FOR THERMAL SPRAY INSTRUMENTATION AND METHOD FOR MAKING THE SAME - A superalloy article which comprises a substrate comprised of a superalloy, a bond coat comprised of MCrAlY wherein M is a metal selected from the group consisting of cobalt, nickel and mixtures thereof applied onto at least a portion of the substrate and a ceramic top coat applied over at least a portion of the bond coat. The bond coat is exposed to a temperature of within the range of between about 1600-1800° F. subsequent to its application onto the substrate. | 05-13-2010 |
| 20100113305 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES - This invention provides a novel method for synthesizing an ensemble of peptides that allows for the generation of an unlimited number of antibiotic compounds. More specifically, the method comprises utilizes synthetic heterocyclic amino acids containing thaizole and/or oxazole as building blocks in a solid phase combinatorial synthesis to yield natural and unnatural antibiotic compounds. | 05-06-2010 |
