| BLUEGNOME LIMITED Patent applications |
| Patent application number | Title | Published |
|---|
| 20110230362 | COMPARATIVE GENOMIC HYBRIDIZATION ARRAY METHOD FOR PREIMPLANTATION GENETIC SCREENING - A method for determining the presence of a copy number imbalance in genomic DNA of a test sample is provided. The method can separately measure hybridization of a single test sample to a first hybridization array and hybridization of a plurality of reference samples to a plurality of other, respective test arrays. A determination of copy number can be based on the best fit reference array, relative to the test array. The best fit can be determined based on the closest or most similar signal-to-noise ratio of the measured signals. | 09-22-2011 |
| 20100113289 | Method and system for non-competitive copy number determination by genomic hybridization DGH - A method and system for determining a copy number of one or more nucleic acid sequences in a test sample are provided. A solid surface with a plurality of probe sets labeled with a first detectable label material bound to the solid surface is provided. The labeled probes are contacted with one or more nucleic acid molecules of the test sample, under conditions suitable for hybridization, so as to form a modified solid surface. The one or more nucleic acid molecules is/are labeled with a second detectable label material. The modified solid surface is scanned to obtain first and second data, which is then mathematically transformed so as to determine the copy number of one or more nucleic acid sequences in the test sample relative to the copy number of the one or more different nucleic acid sequences in the test sample or a reference genome. | 05-06-2010 |
