BIOTEST AG Patent applications |
Patent application number | Title | Published |
20150064170 | Antibody Preparations - An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5% IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5a and/or substantially no C3a. The antibody preparation can have medical uses. | 03-05-2015 |
20140220008 | Humanized Anti-CD4 Antibody With Immunosuppressive Properties - A humanized antibody derived from mouse monoclonal anti-CD4 antibody B-F5 is able to activate CD25+CD4+ regulatory T cells and is useful for preparing immunosuppressive compositions. | 08-07-2014 |
20130045199 | Antibody Preparations - An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5% IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5 | 02-21-2013 |
20120321618 | HUMANIZED ANTI-IL 10 ANTIBODIES FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) - Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (Th-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provided are methods of treatment involving the use of the antibody or fragment thereof. | 12-20-2012 |
20120321617 | HUMANIZED ANTI-IL 10 ANTIBODIES FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) - Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof: (i) binds to the same region of IL-10 as the 1L-10 receptor α (IL-I10Ra) and is not capable of binding IL-10 when the IL-10 is bound to the IL-10 receptor; and (ii) binds to IL-10 in homodimeric form by binding a discontinuous epitope comprising residues of both monomers. Further provided are related products and methods involving the use of the antibody or fragment thereof. | 12-20-2012 |
20100129784 | PERFUSION DEVICE FOR HOLLOW ORGANS, AND THE USE THEREOF FOR THE PERFUSION OF AN EXPLANTED HOLLOW ORGAN - A perfusion liquid is suctioned from a perfusion liquid reservoir ( | 05-27-2010 |
20090237659 | High Throughput Particle Counter - The particle counter is equipped with a scroll pump adapted to create a gas flow through the measurement chamber with a maximum flow rate of at least 50 liters per minute. Light scattered from particles entrained in the gas flow is collected by an optical system. The product of the smallest diameter of the minimum aperture and the magnification amounts to at least 2 mm. Especially preferred is a minimum aperture with a smallest diameter of at least 2.5 mm and a magnification of at least 1.5. The optical system images a projection of the measurement volume created by intersection of the gas flow and the beam of light onto the active area of the sensor module. The sensor module | 09-24-2009 |