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Baylor University

Baylor University Patent applications
Patent application numberTitlePublished
20120130129Efficient Method for Preparing Functionalized Benzosuberenes - The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reaction of a 5-phenylpentanoic acid with Eaton's reagent to form the benzosuberone. The process, optionally, further includes steps for adding a functional group at the ketone position.05-24-2012
20120016124SEROTONIN REUPTAKE INHIBITORS - A serotonin reuptake inhibitor which can be used in the treatment of depression and which has a decreased occurrence of unwanted side effects. The serotonin reuptake inhibitors are bi-functional organic molecules which combine serotonin transporter reuptake inhibition with serotonin (5-HT, such as 5-HT01-19-2012
20110294207SPATIALLY-DEFINED MODIFICATION OF FRESH TISSUE USING COVALENT CHEMISTRY - Methods for modification of tissue using covalent chemistry. Tissue can be modified through direct alkylation, reduction followed by alkylation, or oxidation followed by condensation to covalently attach small organic molecules or appropriately modified proteins. The modification can be spatially limited to desired regions of the tissue surface.12-01-2011
20110250814NON-WOVEN FABRIC COMPOSITES FROM COIR FIBERS - A non-woven fabric composite containing coir fibers and a method for producing such composites. The non-woven fabric composite is comprised of coir fibers, which are large diameter, lignin-rich fibers, with a high viscous flow temperature and a high degradation temperature combined with fibers made of a thermoplastic polymer with a lower viscous flow temperature such as polypropylene (“PP”), polyethylene (“PE”), polylactic acid (“PLA”), and polyester (“PET”) or mixtures thereof. A hot-pressed non-woven fabric composite material prepared from the non-woven fabric composite.10-13-2011
20110250813NON-WOVEN FABRIC COMPOSITES FROM COIR FIBERS - A non-woven fabric composite containing coir fibers and a method for producing such composites. The non-woven fabric composite is comprised of coir fibers, which are large diameter, lignin-rich fibers, with a high viscous flow temperature and a high degradation temperature combined with fibers made of a thermoplastic polymer with a lower viscous flow temperature such as polypropylene, polyethylene or a biodegradable thermoplastic polymer fiber such as polylactic acid, or mixture thereof. A hot-pressed non-woven fabric composite material prepared from the non-woven fabric composite.10-13-2011
20100306878HIGHLY EFFICIENT SUPPRESSOR-DEPENDENT PROTEIN EXPRESSION IN PLANTS WITH A VIRAL VECTOR - A series of viral vectors derived from foxtail mosaic virus, sunn hemp mosaic virus and white clover mosaic virus sequences, and which are capable of expressing heterologous proteins in plants, including the tobacco, 12-02-2010
20100093245NON-WOVEN FABRIC COMPOSITES FROM LIGNIN-RICH, LARGE DIAMETER NATURAL FIBERS - A non-woven fabric composite containing natural fibers and a method for producing such composites. The non-woven fabric composite is comprised of large diameter, lignin-rich natural fibers with a high viscous flow temperature and a high degradation temperature combined with fibers made of a thermoplastic polymer with a lower viscous flow temperature such as polypropylene, polyethylene or a biodegradable thermoplastic polymer fiber such as polylactic acid, or mixture thereof. A hot-pressed non-woven fabric composite material prepared from the non-woven fabric composite.04-15-2010
20100045969METHODS FOR DETERMINING ENANTIOMERIC PURITY WITH VARYING CHIRAL ANALYTE CONCENTRATION - A new strategy for the quantitative determination of enantiomeric purity that combines guest-host complexation, spectroscopy, and chemometric modeling. Spectral data for samples of known enantiomeric composition is subjected to a type of multivariate regression modeling known as partial least squares (“PLS-1”) regression. The PLS-1 regression produces a mathematical model that can be used to predict the enantiomeric composition of a set of samples of unknown enantiomeric purity. In this strategy, the concentration of the chiral compound does not have to be fixed or known.02-25-2010
20090137687Compositions and Methods With Enhanced Therapeutic Activity - This invention relates to novel tricyclic quinone and catechol compositions, compositions containing prodrugs of tricyclic quinone and catechol compositions, and methods of use for the treatment of solid tumor cancers and other vascular proliferative disorders. In certain aspects, the compositions of the invention are capable of generating both a vascular targeting effect and tumor cell cytotoxicity (e.g., by oxidative stress) in order to achieve an enhanced anti-tumor response in a patient.05-28-2009
20090076076INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF - The present invention relates to semicarbazone or thiosemicarbazone inhibitors of cysteine proteases and methods of using such compounds to prevent and treat protozoan infections such as trypanosomiasis, malaria and leishmaniasis. The compounds also find use in inhibiting cysteine proteases associated with carcinogenesis, including cathepsins B and L.03-19-2009
20080215253Method and machine for identifying a chemical compound related applications - The present invention is designed to efficiently calculate isotopic distribution in order to simulate mass spectra data for any chemical compound of interest. The simulated spectra considers the various isotopes of the compound based upon a probability calculation that takes into consideration the natural abundance of each isotope of individual elements of the compound. The probability calculation generates a relative probability associated with each isotope species of the subject compound. The simulated spectra are displayed on an x-y coordinate illustrating the calculated formula weight on the abscissa (x-axis) and the intensity of the specific species on the ordinate (y-axis). This theoretical data is then compared to experimental data taken from a mass spectrometer in order to identify the chemical compound at issue.09-04-2008

Patent applications by Baylor University