Bausch & Lomb Incorporated Patent applications |
Patent application number | Title | Published |
20160022860 | MINIMIZING BIOLOGICAL LIPID DEPOSITS ON CONTACT LENSES - Method for minimizing the sorption of tear lipids on frequent replacement, or extended-wear, contact lenses, the method comprising (a) contacting the contact lens selected from the group consisting of senofilcon A, lotrafilcon A, lotrafilcon B, and comfilcon A B with a lens care solution for a period of at least three hours to minimize the accumulation of tear lipids on the contact lens. The lens care solution comprises 0.5 ppm to 10 ppm α-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl) ammonium chloride; citrate, citric acid or a mixture thereof; and 0.005 wt. % to 0.05 wt. % hyaluronic acid. The method also includes (b) inserting the soaked contact lens into one's eye, and (c) repeating steps (a) and (b). | 01-28-2016 |
20150175732 | LIGHT ABSORBING COMPOUNDS FOR OPTICAL POLYMERS - An optical polymeric material that can substantially block the transmission of ultraviolet light as well as selected portion of violet light. The polymeric material will include monomeric units of one or more lens monomers, and monomeric units of a monomer of formula (I). | 06-25-2015 |
20140206764 | Poly(Nitrogen/Amine) Derivatives of a Natural Wax and Ophthalmic Compositions - A poly(nitrogen/amine) derivative of a natural wax of formula I, and ophthalmic compositions and contact lens care solutions that contain the poly(nitrogen/amine) derivative of a natural wax of formula I. The invention is also directed to a method of treating a patient with dry eyes, the method comprising instructing a patient to administer one or more eye drops of the ophthalmic composition that includes a poly(nitrogen/amine) derivative of a natural wax of formula I. | 07-24-2014 |
20140179867 | MONOMER MIXTURES FOR FORMING SILICON HYDROGELS - A polymerizable monomer mixture containing one or more silicon-containing biomedical device-forming monomers and a diluent; wherein the diluent comprises a boric acid ester of a monohydric alcohol is disclosed. | 06-26-2014 |
20140179824 | METHOD OF PREPARING WATER EXTRACTABLE SILICON-CONTAINING BIOMEDICAL DEVICES - A method of preparing a water extractable silicon-containing biomedical device is disclosed. The method involves curing a monomer mixture comprising one or more silicon-containing biomedical device-forming monomers in the presence of a diluent to produce a silicon-containing biomedical device; wherein the diluent comprises a boric acid ester of a C | 06-26-2014 |
20140142182 | Aqueous Liquid Composition Containing 2-Amino-3-(4-Bromobenzoyl)Phenylacetic Acid - An aqueous liquid composition comprising: (a) 2-amino-3-(4-bromobenzoyl)phenylacetic acid or its pharmacologically acceptable salt or hydrate; (b) a non-ionic surfactant; and (c) a preservative; wherein at least 90 percent of the original amount of said 2-amino-3-(4-bromobenzoyl)phenylacetic acid or pharmacologically acceptable salt or hydrate remains in the composition after storage at 60° C., for 4 weeks. The composition can satisfy the preservative efficacy of US Pharmacopeia 35 (2012). The composition is useful for the treatment of ocular or nasal inflammation of diverse etiology. | 05-22-2014 |
20140135782 | Hingeless Cartridge for Use with an Intraocular Lens Injector Providing Haptic Control - An IOL injector cartridge, comprising an upper wall, a lower wall, the upper wall and the lower wall combining to define a lumen that extends from a proximal end to a distal end, a slot extending through the entire thickness of the upper wall and extending from the proximal end and having a slot distal end formed by the upper wall, an edge of the upper wall that, at least partially defines the slot, having a convex curvature, the curvature occurring along the thickness of the edge. | 05-15-2014 |
20140128686 | OPHTHALMIC MULTIPLE WAVELENGTH LASER ILLUMINATOR WITH A GRAPHICAL USER INTERFACE - An ophthalmic laser illuminator | 05-08-2014 |
20140125954 | System and Method of Calculating Visual Performance of an Ophthalmic Optical Correction Using Simulation of Imaging by a Population of Eye Optical Systems - A method of calculating clinical performance of an ophthalmic optical correction using simulation by imaging a series of objects of different sizes by each of a plurality of eye optical systems, each of the eye optical systems including the ophthalmic optical correction, the method comprising A.) at an object distance, calculating a set of indicia of image quality, each indicium of the set of indicia corresponding to an object in the series of objects when it is imaged by a given one of the plurality of eye optical systems, B.) at the object distance, comparing the set of indicia to a threshold to determine a just-discernable object size for the given one of the plurality of eye optical systems, and C.) repeating steps A and B for each eye optical system in the plurality of eye optical systems. | 05-08-2014 |
20140121608 | IRRIGATION SLEEVE AND PHACOEMULSIFICATION NEEDLE WITH SLEEVE RETENTION FEATURES - A combination of an irrigation sleeve 20 and a phacoemulsification needle 22. The irrigation sleeve 20 has a proximal end 32 and a distal end 30, the proximal end for attachment to a surgical handpiece. The phacoemulsification needle 22 has a proximal end 26, a distal end 24, and a lumen 38 spanning a length of the needle 22 from the proximal end 26 to the distal end 24. The needle proximal end 26 is for connection to the surgical handpiece, and the needle 22 has structure 44 proximate the needle distal end 24 for retaining the sleeve distal end 30 near the needle distal end 24. | 05-01-2014 |
20140074013 | Vibrating Surgical Device for Removal of Vitreous and Other Tissue - An ophthalmic surgical device | 03-13-2014 |
20140034519 | HYDROGEL MONOMER MIX CONTAINING ADDED WATER - Provided herein is a polymerized product formed of a polymerized monomer mixture comprising intentionally added water and at least one hydrophilic monomer wherein the monomer mix does not contain any silicon containing materials. The polymerized monomer mixture of the invention herein is useful in many biomaterial applications. Especially preferred is the use of the biomaterial as a hydrogel contact lens. | 02-06-2014 |
20130314664 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS - A substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis O-hydroxy benzophenone is provided herein. | 11-28-2013 |
20130261190 | Ophthalmic Compositions with Biguanide and PEG-Glycerol Esters - Ophthalmic compositions comprising 0.5 ppm to 5 ppm of alexidine, and 0.005 wt. % to 0.3 wt. % of glycereth-18-ethylhexanoate. The invention is also directed to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone, hydrogel contact lenses. | 10-03-2013 |
20130252946 | Fluoroquinolone Carboxylic Acid Molecular Crystals - Disclosed herein is a molecular crystal form of (R)-(+)-7-(3-amino-2,3,4,5,6,7-hexahydro-1H-azepin-1-yl)-1-cyclopropyl-8-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid. The molecular crystal is characterized by at least one of: (a) an X-ray powder diffraction (“XRPD”) spectrum that comprises peaks at 2θ angles of 10.6, 15, 19.7, 21.1, and 22°±0.2°; (b) a DSC melting peak at 288° C.; (c) a | 09-26-2013 |
20130210912 | Ophthalmic Pharmaceutical Compositions and Methods of Making and Using Same - A stable ophthalmic pharmaceutical composition for relief, treatment, control, alleviation, or prevention of a pathological ocular condition of the eye comprises: (a) a first polymer, a viscosity of which changes with a change in a concentration of an electrolyte, such as a salt, when added to said first polymer; (b) a second polymer that is different from the first polymer and can modify the viscosity of the first polymer; and (c) an oil. In some embodiments, the composition further comprises a non-ionic surfactant. The composition can form a stable oil-in-water emulsion on storage, but separate into an oil phase and a water phase when applied in the eye. The emulsion can comprises an ophthalmic active pharmaceutical ingredient dissolved in the oil or water phase. The emulsion can provide enhanced stability to said active pharmaceutical ingredient. | 08-15-2013 |
20130204269 | Intraocular Lens Injector with Vibration - An intraocular lens injector, comprising an injector body having a lumen wall defining a lumen, a plunger configured and arranged to move an IOL through the lumen, and a vibration source configured and arrange to vibrate at least one of the injector body and the plunger. | 08-08-2013 |
20130203760 | Polymorphs of Brimonidine Pamoate - A brimonidine pamoate polymorph exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system. | 08-08-2013 |
20130201474 | Aberrometer for Measuring Parameters of a Lens Using Multiple Point Sources of Light - A device for measuring a lens, comprising apparatus for maintaining the lens at a location, at least a first point source, a second point source and a third point source, at least a first beam splitter, and a second beam splitter, and a wavefront sensor configured and arranged to receive a wavefront of light from the first source, a wavefront of light from the second source, and a wavefront of light from the third source after the light from each source has passed through the lens. The point sources and beam splitters are arranged such that the first source has a first object distance relative to the location, the second source has a second object distance relative to the location, the third source has a third object distance relative to the location, the first object distance, the second object distance, and the third object distance being different than one another. | 08-08-2013 |
20130197125 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 08-01-2013 |
20130178936 | BRUSH COPOLYMERS - Brush copolymers containing (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units are disclosed. | 07-11-2013 |
20130138093 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX - An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer. | 05-30-2013 |
20130103148 | Intraocular Lens - An intraocular lens comprising: (a) monomeric units derived from at least one cationically polymerizable branched alkene monomer; (b) monomeric units derived from at least one cationically polymerizable monomer having a pendant benzocyclobutene group; and (c) a UV-absorbing benzotriazole component having the formula I. | 04-25-2013 |
20100318185 | Biomedical Devices - Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed. | 12-16-2010 |
20100317817 | Biomedical devices - Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent are disclosed. | 12-16-2010 |
20100317816 | Biomedical devices - Biomedical devices such as contact lenses formed from a comprising a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one or more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed. | 12-16-2010 |
20100317809 | Biomedical devices - Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer comprising one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming monomers are disclosed. | 12-16-2010 |
20100315588 | Biomedical devices - Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a hydrophilic polymer comprising one or more hydrophilic units and one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed. | 12-16-2010 |
20100305514 | INTRAVITREAL INJECTION SYSTEM HAVING COAXIAL CANNULAE AND USE THEREOF - An ophthalmic injection system having coaxial cannulae includes a plurality of syringe bodies and a plurality of cannulae, wherein a first non-flexible cannula is configured to accommodate and guide a second cannula that moves inside the first cannula and penetrates into the internal cavity of an eye globe. The first cannula is long enough to penetrate one or more outer layers of the eye globe. A syringe body is connected to the second cannula for accommodation and infusion of a pharmaceutical composition. A plunger is inserted into an annular space of the second syringe body at its distal end for injecting the pharmaceutical composition to the surgical site. | 12-02-2010 |
20100164129 | Heated Mold Tooling - A method for varying a radius of an optical quality surface of a casting mold formed in a tooling cavity, the tooling cavity at least partially defined by an optical tool having an optical quality surface of a given radius, includes imparting a compressive stress within the optical quality surface of the casting mold to predictably decrease the radius of the optical quality surface of the casting mold. | 07-01-2010 |
20100039613 | SILICONE CONTACT LENSES WITH WRINKLED SURFACE - At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens. | 02-18-2010 |
20100003334 | Combination of loteprednol etabonate and tobramycin for topical ophthalmic use - This invention relates to formulations for topical use comprising antibiotics in combination with anti-inflammatory steroids for treating ophthalmic infections and attendant inflammation. More specifically, this invention relates to pharmaceutical ophthalmic formulations comprising a pH stabilizing amount of tobramycin and the soft steroid loteprednol etabonate. | 01-07-2010 |
20090274745 | Drug delivery systems based on catonic siloxanyl macromonomers - Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: | 11-05-2009 |
20090274744 | Drug delivery system based on cationic siloxanyl macromonomers - Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: | 11-05-2009 |
20090231693 | Device and Method for Demonstrating Optical Effects - An optical system includes two lens systems, one that provides viewing of an object with relatively no spherical aberration, and another that provides viewing of the object with significant spherical aberration. Preferably, both lens systems provide viewing of the object with relatively no chromatic aberration. The optical system may have the configuration of binoculars. | 09-17-2009 |
20090143556 | Polymerizable siloxane-quaternary amine copolymers - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups. | 06-04-2009 |
20090121370 | Molds for Production of Ophthalmic Devices - A mold assembly for the manufacture of at least one ophthalmic device used in or on the eye is disclosed, the mold assembly comprising a mateable pair of mold parts wherein at least one of the mold parts is made from a polymeric resin comprising a polymer backbone and one or more pendent groups having peroxide functionality and covalently linked to the polymer backbone. | 05-14-2009 |
20090112222 | IOL Insertion Apparatus - An apparatus for inserting an intraocular lens through a small incision into an eye is disclosed comprising a hollow tube including an interior wall defining a hollow space through which an intraocular lens may be passed and an outlet through which the intraocular lens may be passed from the hollow space into the eye, wherein at least the hollow tube of the apparatus is obtained from at least a polymeric resin comprising a polymer backbone and one or more pendent groups having peroxide functionality and covalently linked to the polymer backbone. | 04-30-2009 |
20090111942 | Method for Making Surface Modified Biomedical Devices - Disclosed are methods for making a surface modified biomedical device involving (a) exposing a biomedical device having a plurality of biomedical device surface functional groups to one or more ethylenically unsaturated-containing organic compounds having a reactive group that is co-reactive to the biomedical device surface functional groups of the biomedical device; and (b) graft polymerizing a hydrophilic reactive monomer having a complementary reactive functionality with the ethylenically unsaturated functionalities of the ethylenically unsaturated-containing organic compounds on or near the surface of the biomedical device thus forming a biocompatible surface on the biomedical device. The methods disclosed are two-step methods and do not include any additional surface treatment steps. | 04-30-2009 |
20090108479 | Method for Making Biomedical Devices - A method of preparing a biomedical device is disclosed. The method involves the steps: (a) cast molding at least one biomedical device formed from a monomer mixture comprising at least one silicone-containing monomer and at least one hydrophilic monomer in a mold assembly, the mold assembly comprising at least one anterior mold part made of a first plastic material and one posterior mold part made of a second plastic material, wherein the first plastic material is more polar relative to the second plastic material; and (b) contacting a surface of the biomedical device with a solution comprising a proton-donating wetting agent, whereby the wetting agent forms a complex with the hydrophilic monomer on the surface of the biomedical device. | 04-30-2009 |
20090108478 | Molds for production of ophthalmic devices - A mold assembly for the manufacture of at least one ophthalmic device used in or on the eye is disclosed. The mold assembly includes a mateable pair of mold parts wherein at least one of the mold parts comprises at least an oxygen-absorbing mold material and an oxygen scavenger composition containing (i) an oxygen scavenging polymer comprising a polymer backbone and one or more substituted or unsubstituted cyclic olefinic groups covalently linked to the polymer backbone; and (ii) an oxygen scavenging catalytic amount of a transition metal catalyst. | 04-30-2009 |
20090100801 | Packaging Solutions - A packaging system for the storage of an ionic, hydrogel contact lens employs an aqueous packaging solution including a phosphorylcholine polymer. Preferably, the solution has an osmolality of at least about 200 mOsm/kg, a pH of about 6 to about 8 and is heat sterilized. | 04-23-2009 |
20080314767 | Ophthalmic Solutions - Disclosed are ophthalmic solutions such as packaging solutions for storing ophthalmic devices and lens care solutions for cleaning, disinfecting, rinsing and/or storing ophthalmic devices. The ophthalmic solutions contain at least a polymerization product obtained from a monomeric mixture comprising (a) a monomer bearing a center of permanent positive charge and (b) a non-ionic ethylenically unsaturated monomer, wherein the solution has an osmolality of at least about 200 mOsm/kg, and a pH of about 4 to about 9. | 12-25-2008 |
20080312397 | Silicone-Containing Prepolymers - Prepolymers comprising at least one block of Formula II and terminated with a polymerizable ethylenically unsaturated radical are useful in hydrogel materials are disclosed: | 12-18-2008 |
20080206481 | SILICONE CONTACT LENSES WITH WRINKLED SURFACE - At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens. The wrinkled surface is formed by subjecting the surface to a high energy source. | 08-28-2008 |
20080196748 | System and Method for Cleaning Process Trays - An electronically controlled programmable system and method for removing debris such as stray contact lenses adhered to process trays. A combination of low and high pressure aqueous sprays is applied to surfaces of a process tray to be cleaned thereby disturbing and removing stray lenses adhered to the tray. The sprays also hydrate dried contact lenses to assist in breaking their adhesive bond to the tray. After removal of stray lenses the system washes and rinses the trays using filtered mains water, purified or distilled water. Trays are automatically loaded and unloaded to and from a cleaning zone within the system. | 08-21-2008 |