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ARKRAY, INC.

ARKRAY, INC. Patent applications
Patent application numberTitlePublished
20120130213ELECTROCHEMICAL SENSOR - An electrochemical sensor includes a base plate including one end portion and another end portion, an electrode portion formed on the one end portion of the base plate, a connecting portion, formed on the another end portion of the base plate, for electrically connecting the electrode portion to a monitoring instrument, and an attaching portion formed on the another end portion, the attached portion being employed for attaching the another end portion to the monitoring instrument in a state where the one end portion is enabled to swing relatively to the monitoring instrument.05-24-2012
20120129174Target Sequence Amplification Method, Polymorphism Detection Method, and Reagents for Use in the Methods - An object of the present invention is to provide an amplification method that inhibits amplification caused by erroneous annealing of a primer. Primers X1 and X2 are used in amplification of a target sequence including a target site showing a polymorphism. The primer X1 includes a sequence A1′ and a sequence E1. The sequence A1′ is complementary to a partial sequence A1 in a template nucleic acid, and has, in its 3′ region, a base x1′ complementary to a first base x1 at the target site in a 5′ region of the sequence A1. The sequence E1 is noncomplementary to a partial sequence B1 adjacent to the 3′ end of the partial sequence A1 in the template nucleic acid, and is bound to the 5′ end of the partial sequence A1′. The primer X2 includes a sequence A2′. The sequence A2′ is complementary to a partial sequence A2 in the template nucleic acid, and has, in its 3′ region, a base x2′ complementary to a second base x2 at the target site in a 5′ region of the partial sequence A2. Each of the primers X1 and X2 has a base complementary to the target site in its 3′ region. By these primers, when only a template in which the target site is the first base x1 is present, erroneous amplification of the target sequence having the second base x2 can be prevented. Thus, a false positive for the polymorphism of the second base x2 can be inhibited.05-24-2012
20120125774Analysis Chip and Analysis Apparatus - An analysis chip that enables an apparatus to be small, analysis to be simple, analysis time to be short and analysis of both glycosylated hemoglobin and glucose to be highly accurate is provided. The electrophoresis chip includes an upper substrate 05-24-2012
20120125773Analysis Chip and Analysis Apparatus - An analysis chip that enables an apparatus to be small, analysis to be simple, analysis time to be short and analysis of both glycosylated hemoglobin and glucose to be highly accurate is provided. The electrophoresis chip includes an upper substrate 05-24-2012
20120116706Analysis Device and Analysis Method - Provided is an analysis device or an analysis method, by which highly reliable analysis results can be obtained even in the circumstances where environment temperature changes, while reducing load on the user. The analysis device (05-10-2012
20120116190Continuous Analysis Device And Sample Component Control System - A continuous analysis apparatus capable of transmitting information about components in body fluid to another apparatus such as medicine dosing apparatus more correctly without giving a user displeasure. The continuous analysis apparatus according to the present invention includes a sensing unit 05-10-2012
20120114771Oxidized Protein Hydrolase Activity Enhancer - The present invention provides an enhancer for enhancing the activity of oxidized protein hydrolase. The oxidized protein hydrolase activity enhancer according to the present invention contains an extract of at least one plant selected from the group consisting of 05-10-2012
20120110054Information Provision System, Information Provision Method, Program, and Server Device - When continuous user biometric information is transmitted to a server device continuously from a handheld device used by a user, the server device can be caused to receive a required measurement value efficiently at a required time, select information desired by the user on the basis of the measurement value and user peripheral information, and provide the user with the information reliably, without imposing excessive communication charges and the like. A server device 05-03-2012
20120109010ELECTROCHEMICAL SENSOR, LANCET, AND BODILY FLUID MEASURING APPARATUS - An electrochemical sensor includes a base plate provided with a concave part formed on one of surfaces thereof, a fluid channel formed so that a bottom part of the concave part and the other one of the surfaces of the base plate are communicated with each other, a plurality of electrodes formed on the concave part; a reagent fixed on the electrodes, a cover which covers the concave part, and an air channel which causes the inside and outside of the concave part to be communicated with each other.05-03-2012
20120107903Mutant Glucose Dehydrogenase - A mutant glucose dehydrogenase having an amino acid sequence at least 80% identical to SEQ ID NO:3 and having glucose dehydrogenase activity, wherein amino acid residues corresponding to positions 326, 365 and 472 of said amino acid sequence are replaced with glutamine, tyrosine and tyrosine, respectively, and wherein said mutant glucose dehydrogenase shows an improved substrate specificity to glucose and a reduced reactivity to disaccharides.05-03-2012
20120107816Primer Set for Detecting EGFR Exon 21 Polymorphism and Application Thereof - The invention provides a primer set for detecting a polymorphism in EGFR exon 21 L858R. The primer set has a P1 oligonucleotide and a P2 oligonucleotide and can performing amplification by using a region including the 172792nd base of SEQ ID NO: 1 as a template. As a base that is complementary to the 172792nd base of SEQ ID NO: 1, the P1 oligonucleotide has cytosine and the P2 oligonucleotide has adenine. The melting temperature of the P1 oligonucleotide is higher than the melting temperature of the P2 oligonucleotide, and/or the P1 oligonucleotide is one or more bases longer than the P2 oligonucleotide. The invention further provides a polymorphism detection primer, a polymorphism detection method using the primer set, a method of evaluating a EGFR tyrosine kinase inhibitor using the primer set, a primer used in the polymorphism detection method, and a kit including the primer set.05-03-2012
20120107815Polymorphism Detection Probe, Polymorphism Detection Method, Evaluation of Drug Efficacy, and Polymorphism Detection Kit - The invention provides a probe which detects a polymorphism in the MDR1 gene. The probe has a P1 and/or a P2 oligonucleotide. The P1 oligonucleotide has a sequence that is complementary to a first base sequence, in which the first base sequence is a partial sequence of SEQ ID NO: 2 having a length of from 13 bases to 68 bases and including the 288th to 300th bases of SEQ ID NO: 2. The base complementary to the 288th base is labeled with a fluorescent dye. The P2 oligonucleotide has a sequence that is complementary to a second base sequence, in which the second base sequence is a partial sequence of SEQ ID NO: 2 having a length of from 6 bases to 93 bases and including the 300th to 305th bases of SEQ ID NO: 2. The base complementary to the 305th base is labeled with a fluorescent dye.05-03-2012
20120105470HbA1c Measurement Result Display Method, and Display Device - A method for displaying HbA1c measurement results is provided, which makes it possible to prevent overlooking a sample that exhibits an HbA1c value at a predetermined level different from a normal value, for example, a sample that exhibits a diabetic type. The method is a display method for displaying spectrum data as results of measurement of hemoglobin A1c (HbA1c) in a sample by separation analysis, and the method includes applying one of at least two different types of designs to a peak area for HbA1c in the spectrum data, according to an amount of HbAlc in the sample, or according to the amount of HbA1c and an amount of blood glucose in the sample.05-03-2012
20120103054CALIBRATION METHOD IN MEASUREMENT OF HEMOGLOBIN A1c - A calibration method that enables calibration easily in a short time in a measurement of hemoglobin A1c by use of a separation analysis is provided. In a measurement of a hemoglobin A1c amount by use of a separation analysis, a one-point calibration using a single calibration standard is performed to obtain calibration data to be used for correcting a measured value.05-03-2012
20120101739Chromatogram Display Method, Data Processing Device, and Analysis Device - A novel method for displaying a chromatogram that is capable of displaying a chromatogram with improved visibility is provided. This is a method for displaying a chromatogram having a time axis as a horizontal axis, based on analysis data of a target object in a sample, the method including displaying a chromatogram in which the scale of the time axis for a predetermined time period is altered.04-26-2012
20120100567Measurement Method Using Oxidase - A method for measuring a target object in a sample by using an oxidase, wherein the influence of dissolved oxygen in the sample can be corrected, is provided. The method comprises: obtaining measurement values by causing the target object in the sample to react with the oxidase under different conditions of two or more types; and performing a correction based on the obtained two or more measurement values and a correction method preliminarily set so as to correct the influence of dissolved oxygen in the sample.04-26-2012
20120087863Peptide Derivative and Use of the Same - A new peptide derivative is provided. The peptide derivative is represented by the following general formula (I),04-12-2012
20120075623ANALYZING APPARATUS - An analyzing apparatus includes a microchip, a detecting unit and an analyzing-measuring unit. The microchip is formed of a light transmissive material formed with a separation fluid channel that is a light measuring part. The detecting unit includes an emitted-light guiding unit that emits light to the separation fluid channel, and a received-light guiding unit that receives light through the separation fluid channel. The emitted-light guiding unit or the received-light guiding unit placed at a position facing a microchip support table via the microchip abuts the microchip, and pushes the microchip in a direction toward the microchip support table. The analyzing-measuring unit includes the detecting unit, the emitted-light guiding unit and the received-light guiding unit, and detects a constituent of a sample filled in the separation fluid channel.03-29-2012
20120040466Analytical Method of Hemoglobin - A method for analyzing hemoglobin in a sample by separation analysis while suppressing the denaturation of the hemoglobin includes separating hemoglobin in the presence of at least one of a sulfurous acid compound and a dithionous acid compound.02-16-2012
20120037508Electrophoresis Apparatus and Control Method Thereof - An electrophoresis apparatus that applies voltage from electrodes that are provided in a capillary flow channel and causes component separation by performing electrophoresis on a specimen that is injected into the capillary flow channel comprises: a physical quantity acquisition unit and a physical quantity determination unit. The physical quantity acquisition unit, with migration solution and specimen injected inside the capillary flow channel, acquires an electrical quantity that occurs in the capillary flow channel at a specified time when voltage is being applied to the electrodes. The physical quantity determination unit determines whether or not the electrical quantity that the physical acquisition unit acquires is within a specified range.02-16-2012
20120035441MOUNT UNIT, SENSOR UNIT, MEASUREMENT APPARATUS AND SENSOR FIXATION METHOD - A mount unit 02-09-2012
20120034140SAMPLE ANALYSIS TOOL, METHOD FOR PRODUCING SAMPLE ANALYSIS TOOL, AND METHOD FOR INHIBITING DECREASE IN LIQUID PERMEABILITY OF DEVELOPMENT MEMBER - Provide is a sample analysis tool whose reactivity and reproducibility in analysis can be prevented from decreasing. The sample analysis tool 10 of the present invention includes a development member 11 and a plastic base 16, and at least part of the development member 11 is in contact with the plastic base 16. The sample analysis tool 10 further includes a hydrophilic component layer 15, and the hydrophilic component layer 15 is formed on part or the whole of at least one of a surface of the plastic base 16 and a surface of the development member 11. It is particularly preferable that the hydrophilic component layer 15 contains sucrose or N-methyl glucosamine. In the sample analysis tool 10 of the present invention, since the hydrophilic component layer 15 is formed on part or the whole of at least one of the surface of the plastic base 16 and the surface of the development member 11, it is possible to prevent the adhesion of a hydrophobic component(s) derived from the plastic base 16.02-09-2012
20120031761ANALYSIS APPARATUS - An analysis apparatus enables a plurality of analysis processes to be accurately and efficiently performed. The analysis apparatus includes a detention tank in which a specimen is stored, and a voltage applier. The voltage applier includes a power source and a contact tip to be brought into contact with the specimen for applying a voltage necessary for analyzing the specimen. The voltage applier renews the contact tip from a used state to an unused state after completing an analysis and before starting the subsequent analysis.02-09-2012
20120031206ANALYSIS METHOD, SAMPLE ANALYSIS TOOL, METHOD FOR PREVENTING BACK-FLOW OF SAMPLE SOLUTION, AND METHOD FOR PREVENTING INCREASE IN BACKGROUND - Provided is an analysis method in which increase in a background can be prevented in a simple manner without cost. The analysis method of the present invention is carried out using a sample analysis tool 02-09-2012
20120029942User-Specific Data Provision System, User-Specific Data Provision Method, Server Device, and Handheld Device - A user-specific data provision system includes: a handheld device transmitting user-specific information held specifically by a user and user's biometric information acquired by measuring biometric information of the user; the server device receiving the user-specific information and the user's biometric information; and a medical facility terminal receiving information transmitted from the server device, a server device including an access point information determining unit acquiring access point information representing an access point to which the handheld device belongs at present and determining whether the access point is changed or not, at least one of the handheld device and the server device, further including a biometric information prediction determining unit determining whether or not the user's biometric information satisfies a predetermined criterion, wherein the server device transmits the user-specific information to the medical facility terminal when determining that the access point is changed and/or when determining that the predetermined criterion is satisfied.02-02-2012
20120029332Method of Continuously Measuring Substrate Concentration - Analysis equipment is provided, which is capable of fulfilling a demand for miniaturization and ensuring high sensitivity, and which can be produced easily. The present invention relates to a method of continuously measuring a substrate concentration based on a response when a voltage is applied to a sensor. The present invention includes a response voltage application step of applying a response voltage E2 at which a response attributed to a substrate is obtained and a non-response voltage application step of applying a non-response voltage E1 at which the response attributed to the substrate is not obtained or is not substantially obtained. Preferably, the response voltage application step and the non-response voltage application step are repeated alternately.02-02-2012
20120021451SAMPLE ANALYSIS APPARATUS AND SAMPLE ANALYSIS METHOD - An analysis apparatus includes a plurality of separation channels, a detector, and a control unit. In each separation channel, a particular component contained in a sample is separated from other components. The detector detects the separated particular component. The control unit controls an analysis step and a preprocessing step. The analysis step includes a separation step of performing the separation and a detection step of performing the detection in each separation channel. The preprocessing step is performed to put each separation channel into a state in which it can perform the analysis step. The control unit simultaneously carries out at least parts of the preprocessing steps of at least two of the plurality of separation channels.01-26-2012
20120021438Method of Detecting Target, Method of Suppressing Increase in Background and Detection Apparatus - Provided are a method of detecting a target with high accuracy, a method of suppressing an increase in background, and a detection apparatus.01-26-2012
20120021419Analyzing System, Analyzing Apparatus, Container, Analyzing Method, Program, and Recording Medium - An analyzing system that enables further expansion of analysis items and automation of analysis. In the analyzing system for performing an analysis using container 01-26-2012
20120021413Method for Detecting Mutation in Exon 12 of JAK2 Gene, and Nucleic Acid Probe and Kit Therefor - A probe for detecting a polymorphism in exon 12 of the JAK2 gene, the probe comprising at least one of the oligonucleotides in (a) to (c) below: 01-26-2012
20120018302BIOSENSOR UNIT AND BIOSENSOR SYSTEM - The biosensor unit has a substrate composed of a subcutaneously retained part that is retained under the skin and a base part that is placed on the skin surface. The biosensor unit comprises a sensor part detecting numerical information regarding a substance to be measured as electric signals, a signal amplifying part amplifying the electric signals, a CPU including a calculation part A/D converting the amplified electric signals and processing them to create transmittable data, a storage storing electric signals and data, a transmission part transmitting data to an external device through optical communication, and a battery part for drive. The sensor part is provided on the subcutaneously retained part and the transmission part is provided on the base part.01-26-2012
20120017706Method and Apparatus for Displaying Chromatogram - A method for displaying a chromatogram as a combination of HbA1c region where HbA1c elutes and HbA0 region where HbA0 and one or more variant Hb's elute, the method includes steps of: determining, based on priority levels of HbA0 and one or more variant Hb's, display form of the HbA0 region so that a peak of a component with higher priority level among HbA0 and one or more variant Hb's whose peaks are to be displayed in the HbA0 region is displayed more preferentially; and displaying the HbA0 region in the determined display form and the HbA1c region, concurrently.01-26-2012
20120015450Method for Detecting Prozone Phenomenon, Analysis Method, Device for Detecting Prozone Phenomenon, and Analysis Device - Provided is a prozone phenomenon detecting method, by which generation of a prozone phenomenon can be detected even when a conventional specimen analysis tool is used, and examinations using an immunochromatography method and the like can be performed efficiently. In the method, a specimen analysis tool containing substances that specifically bind to a target component contained in a sample is used. The specimen analysis tool is obtained by arranging a sample supplying portion, a reagent portion, and a detection portion on the porous base material from upstream to downstream in a sample moving direction in this order. The reagent portion contains a labeled substance that specifically binds to the target component. The detection portion contains an immobilized substance that specifically binds to the target component. The target component is detected by detecting a complex of the target component, the labeled substance, and the immobilized substance through detection of a label of the labeled substance in the detection portion. The method includes at least one of the following processes A and B: the process A: a process in which detection results obtained in the detection portion are plotted along the sample moving direction, and generation of a prozone phenomenon is detected on the basis of a position of a peak in plots thus obtained; and the process B: a process in which the label is detected at two or more different time points in the detection portion, and generation of a prozone phenomenon is detected on the basis of a magnitude relationship between two or more detection results thus obtained.01-19-2012
20120015388Diluent for Preparing Analytical Sample - The ionic strength of a diluent for preparing an analytical sample is set to be 0.06 to 0.16. The analytical sample prepared by using the diluent having the ionic strength within this range can be subjected to both for analyzing a first object in a test sample by electrode method and for analyzing a second object in the test sample by liquid chromatography method, and high-precision measurement can be attained. The analytical sample is especially useful for preparing a sample for measurement used both for measuring glucose concentration in a blood sample by enzyme electrode method and for measuring glycohemoglobin concentration in the blood sample by liquid chromatography method.01-19-2012
20120010821Nucleic Acid Abundance Ratio Measurement Device, Method, and Program Storage Medium, Determination Method and Nucleic Acid Abundance Ratio Measurement Kit - A nucleic acid abundance ratio measurement device includes a detection section that detects a detection signal over different temperature ranges of a melting curve for a nucleic acid mixture having one or more melting temperatures, and an abundance ratio computation section that computes a nucleic acid abundance ratio based on a ratio of characteristic amounts obtained from the detection signal detected by the detection section and based on detection amount data.01-12-2012
20120009611BIOSENSOR AND BIOSENSOR MANUFACTURING METHOD - A biosensor manufacturing method including a sheet material forming process and a dicing process. In the sheet material forming process a sheet material with plural biosensor forming sections is formed. Each of the biosensor forming sections includes a first base plate, a second base plate stacked on the first base plate and forming a capillary between the second base plate and the leading end portion of the first base plate for sucking in sample liquid, and a hydrophilic layer formed on the second base plate at least in a region facing the capillary. In the dicing process plural biosensors are obtained by dicing the sheet material with a blade from the first base plate side at the leading end of each of the biosensor forming sections, such that the leading end of the capillary opens onto the leading end face of the first base plate and the second base plate.01-12-2012
20120009576Probe for Detection of Polymorphism in ABL Gene, and Use Thereof - A probe for detecting a polymorphism in ab1 gene, said probe comprising at least one fluorescence-labeled oligonucleotide selected from P1 below: 01-12-2012
20110318767Method for Measuring Plasma Glucose - A measurement of plasma glucose is carried out through the following steps, a sample preparation step (S12-29-2011
20110308944Electrochemical Sensor and Method for Manufacturing Same - The present invention provides an electrochemical sensor comprising a substrate, an electrically conductive layer made of carbon particles which is disposed on the substrate, a cell membrane mimetic structure layer containing an enzyme at least one of inside the cell membrane mimetic structure layer and on the interface of the cell membrane mimetic structure layer which is disposed on the electrically conductive layer.12-22-2011
20110306957LASER DRILLING DEVICE AND PROTECTIVE MEMBER AND CARTIDGE FOR LASER DRILLING DEVICE - The present invention is directed to a laser perforation apparatus including a laser light oscillator for emitting laser light that radiates skin, and a protection member 12-15-2011
20110300565ANALYSIS METHOD, ANALYSIS DEVICE, PROGRAM USED TO IMPLEMENT SAID ANALYSIS METHOD, AND STORAGE MEDIUM AND RETRIEVAL DEVICE FOR THIS PROGRAM - An analysis apparatus includes a first analysis unit which collects samples by utilizing a first nozzle to analyze the sample, a second analysis unit which collects samples by utilizing a second nozzle to analyze the sample, and a transport apparatus which transports a plurality of sample vessels along a predetermined transport route. When a predetermined waiting state is provided such that the transport of the plurality of sample vessels is interrupted or stopped, then the sample collecting position is changed for at least one of the first and second nozzles, and the samples are collected from the plurality of sample vessels by means of the nozzle having the changed position. Accordingly, it is possible to enhance the efficiency of the analysis process performed by the analysis apparatus, while suppressing the transport apparatus from being large-sized and suppressing the structure from being complicated.12-08-2011
20110300539Method for Detecting Polymorphism at Nucleotide Position -1639 of VKORC1 Gene, and Nucleic Acid Probe and Kit Therefor - A probe for detecting a polymorphism at position −1639 of the VKORC1 gene, the probe comprising an oligonucleotide having a nucleotide sequence having a length of 10 to 50 nucleotides, which nucleotide sequence comprises the nucleotides 80 to 89 of SEQ ID NO:1 or 2 and has a homology to SEQ ID NO:1 or 2 except that the nucleotide corresponding to the nucleotide at position 80 in SEQ ID NO:1 or 2 is cytosine, which nucleotide corresponding to the nucleotide at position 80 is labeled with a fluorescent dye.12-08-2011
20110275126Method for Producing Nucleic Acid Sample and Method for Producing Nucleic Acid Amplification Product Using the Same - Provided are a simple method for producing a nucleic acid sample that does not need to use high-risk chaotropic salt in large amounts, does not need to use a limited special carrier, and offers a superior level of safety; and a method for producing a nucleic acid amplification product using the same. With respect to a cell sample containing cells, by releasing nucleic acid complexes from the cells and bringing this treatment liquid into contact with a carrier, the nucleic acid complexes are held in the carrier. Further, in the presence of a dispersion medium, by applying heat treatment to the carrier, DNAs such as genomic DNA and mitochondrial DNA, and RNA are released. Thereby, a nucleic acid sample can be recovered.11-10-2011
20110269164Measuring Device, Measuring Method, and Program - A measuring device (11-03-2011
20110262992METHOD FOR STABILIZING LABELED ANTIBODY - The present invention relates to a method for stabilizing a labeled antibody in a solution, in which the labeled antibody is stabilized by allowing the labeled antibody to be present together with at least one of amino acid and a derivative thereof in the solution.10-27-2011
20110259741Biosensor - A biosensor includes a first working electrode that a biocatalyst, which has a property that reacts on a specified ground substance, is disposed, a second working electrode that the biocatalyst, which the property is lost, is disposed, and at least one counter electrode for respectively applying a voltage to the first working electrode and the second working electrode.10-27-2011
20110257533BIOLOGICAL INFORMATION MEASUREMENT DEVICE, ILLUMINATION METHOD IN A BIOLOGICAL INFORMATION MEASUREMENT DEVICE, AND BIOLOGICAL INFORMATION MEASUREMENT METHOD - A biological information measurement device that measures biological information of a user includes: a device main body; a fitting-removal section which is provided in the device main body, and to/from which a sensor that measures the biological information is fitted/removed; a light source section that is provided within the device main body at a position spaced apart from the fitting-removal section and that functions as a light source for components of the biological information measurement device other than the fitting-removal section; and a light guide member that guides light emitted by the light source section to a predetermined position in the vicinity of the fitting-removal section to/from which the sensor is fitted/removed.10-20-2011
20110244460METHOD FOR DETECTING CONTROLS FOR NUCLEIC ACID AMPLIFICATION AND USE THEREOF - The present invention provides a control detection method for easily detecting a positive control and a negative control simultaneously in one reaction system. An amplification reaction is carried out by adding a control template nucleic acid to a reaction system for detecting controls. The template nucleic acid can be amplified by a primer capable of amplifying an objective target sequence. An amplification region of the control template nucleic acid amplified by the primer can be hybridized with a detection probe capable of hybridizing to the target sequence. A Tm value (Tm10-06-2011
20110217207ANALYSIS TOOL, IDENTIFICATION APPARATUS, AND ANALYSIS APPARATUS - A technique is provided, which makes it possible to easily judge whether or not an analysis tool to be used for an analysis process for a sample is authentic and which makes it possible to secure the reliability of an analysis result thereby. An identification apparatus for identifying an analysis tool having a reagent portion to be used for an analysis process for a sample is provided, wherein the analysis tool further includes an identifying marker portion which is formed by using an invisible substance, the identification apparatus comprising a light emitter which emits a light toward the identifying marker portion, a light receiver which receives a light emitted by the invisible substance for forming the identifying marker portion exposed with the emitted light emitted by the light emitter, and an identification unit which identifies the analysis tool on the basis of a light-receiving result obtained by the light receiver.09-08-2011
20110206605Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe comprises a polypeptide represented by the following formula (1), (2), or (3), or a polypeptide having homology with the foregoing polypeptide,08-25-2011
20110204139Data output method in analysis of sample, analytical device, and analytical system - An analytical device is provided that can easily determine whether analysis results are affected by drug administration for the test subject when a sample such as urine or blood is analyzed. The analytical device includes reading means capable of reading test subject identification information recorded on an information recording portion of a sample container, and data output means capable of outputting data on analysis results of a sample contained in the sample container, the analytical device further having: information acquiring means capable of acquiring, from a source external to the analytical device, drug administration information on the test subject corresponding to the test subject identification information read by the reading means, wherein when the data on analysis results of a sample are outputted by the data output means, data on the drug administration information on the test subject corresponding thereto are also outputted.08-25-2011
20110204133CODE READING DEVICE AND DATA COLLECTION SYSTEM USING THE SAME - The present invention provides a code reading device capable of associating various kinds of information with obtained data with ease simply by connecting the code reading device to a data holding device. A code reading device (08-25-2011
20110186511LIQUID CHROMATOGRAPHY APPARATUS AND LIQUID CHROMATOGRAPHY - A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.08-04-2011
20110185797ANALYZING DEVICE AND METHOD FOR CONTROLLING SAME - An analyzing device includes a feeder connected to a container in which a sample is contained for sucking the sample from the container and feeding the sample, and a controller for performing control for feeding from the feeder to a measurer. In measuring the sample, the controller performs control so that results of a plurality of times of measurement are obtained with respect to the single container in which the sample is contained, without changing the container. This arrangement allows quick accuracy check.08-04-2011
20110182775ANALYTICAL INSTRUMENT AND METHOD FOR MANUFACTURING SAME - An analytic instrument (07-28-2011
20110179856ANALYZING DEVICE - A liquid chromatography device includes a column containing a filler, an injection valve capable of introducing a sample into the column and also capable of introducing a liquid mobile phase into the column, and a mobile phase feeder for feeding the liquid mobile phase from a mobile phase container containing the liquid mobile phase to the column via the injection valve. Between the mobile phase container and the injection valve is provided a storage chamber for temporarily storing the liquid mobile phase sent from the mobile phase container. The device further includes a liquid level detection sensor for detecting the liquid level of the liquid mobile phase in the storage chamber. This structure allows the liquid for use in analysis to be used completely without being wasted.07-28-2011
20110174708SAMPLE STIRRING DEVICE, LIQUID CHROMATOGRAPHY DEVICE USING SAME, AND SAMPLE CONTAINER STAND - A sample stirring device of the present invention includes a driving roller and two follower rollers for coming into contact with a sample container including a cylindrical portion for containing a sample to be stirred. The driving roller is driven for rotation to stir the sample contained in the sample container. The two follower rollers have rotation axes inclined with respect to an axial direction of the cylindrical portion. This arrangement allows the sample container such as a blood collection tube to be rotated stably.07-21-2011
20110174638MONITORING DEVICE AND MONITORING METHOD - A monitoring device which measures numerical value information on a subject substance in a body fluid has an electrochemical sensor including a sensor unit for detecting the subject substance which is used in the way of being embedded subcutaneously and generating an electric signal correlating to the numerical value information on the subject substance, and a temperature control unit which adjusts the detected ambient temperature as a temperature ambient to a sensor unit when detecting the subject substance so as to reach a target setting temperature when measuring the subject substance.07-21-2011
20110174081ANALYSIS DEVICE PROVIDED WITH FLOW SENSOR, AND FLOW SENSOR ADJUSTMENT METHOD - The present invention relates to a method of adjusting a flow rate sensor 07-21-2011
20110171129Molecular Probe Precursor for Imaging of Pancreatic Islet, and Use Thereof - A precursor of a molecular probe for imaging of pancreatic islets is provided. The precursor includes a polypeptide represented by any one of the following formulae (1) to (12), or a polypeptide having a homology with the foregoing polypeptide:07-14-2011
20110162458FLOW SENSOR AND ANALYSIS DEVICE PROVIDED WITH SAME - The present invention relates to a flow rate sensor 07-07-2011
20110155573METHOD OF ANALYZING HEMOGLOBIN BY ELECTROPHORESIS - A method for analyzing hemoglobin by electrophoresis, capable of analyzing hemoglobin A1c (HbA1c) and modified hemoglobin with improved accuracy in a shortened analysis time is provided. The method for analyzing hemoglobin by electrophoresis includes performing electrophoresis under conditions in which an acidic substance having two or more carboxyl groups is present in an electrophoresis solution. At least two of the carboxyl groups of the acidic substance each have an acid dissociation constant (pK06-30-2011
20110154910ANALYSIS DEVICE AND ANALYSIS METHOD - The present invention relates to an analysis apparatus 06-30-2011
20110154888ANALYSIS DEVICE - The present invention relates to an analysis apparatus 06-30-2011
20110130781METHOD OF SETTING LANCING MEMBER TO LANCING DEVICE, LANCING DEVICE, AND CAM MECHANISM - A lancing member (06-02-2011
20110130681SAMPLE COLLECTION IMPLEMENT - A sample collection implement S06-02-2011
20110117568Method for Amplifying Target Nucleic Acid Sequence, Method for Detecting Mutation Using the Same, and Reagent Used for the Same - The present invention provides a method for detecting a mutation capable of detecting a mutation with high sensitivity and high reliability in one reaction system. Using primers (Xmt) and (Xwt), a target nucleic acid sequence whose objective base to be detected is a mutant-type is amplified with amplification efficiency higher than a target nucleic acid sequence whose objective base to be detected is a normal-type. The (Xmt) is a primer that is complementary to a region including a mutant-type base in the template nucleic acid and has a base complementary to a mutant-type base at a 3′ region, and the (Xwt) is a primer that is complementary to a region including a normal-type base in the template nucleic acid and has a base complementary to a normal-type base at a 3′ region. It is preferable that amplification efficiency by the (Xmt) with reference to a mutant-type template nucleic acid is higher than that by the (Xwt) with reference to a normal-type template nucleic acid. Then, a signal value that shows a molten state of a hybridization product between the thus obtained amplification product and the probe is measured, and the presence or absence of the mutation of the objective base site is determined from a change in the signal value accompanying a change in the temperature.05-19-2011
20110117136DEHYDROEPIANDROSTERONE PRODUCTION PROMOTER AND USE THEREOF - A new orally administerable DHEA production promoter is provided. A composition containing an extract of at least one selected from the group consisting of plants of Rosaceae 05-19-2011
20110094881SENSOR CARTRIDGE AND MEASURING DEVICE - A sensor cartridge for supplying a sensor is used. The sensor cartridge includes a casing within which the plurality of sensors can be arranged, and that allows a sample to be introduced to a sensor located at a preset location, and a connection structure. The connection structure electrically connects an external device and a sensor electrode of the sensor located at the preset location. The casing is formed so as to be held by the external device when the external device and the sensor electrode of the sensor are electrically connected via the connection structure.04-28-2011
20110081663Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - A molecular probe for imaging of pancreatic islets is provided. The molecular probe includes a polypeptide represented by the following formula (1), or a polypeptide that has a homology with the foregoing polypeptide.04-07-2011
20110076707MUTANT GLUCOSE DEHYDROGENASE - Substrate specificity for glucose of a glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 13 is improved by substituting another amino acid residue for the amino acid residue at position 472 and/or 475.03-31-2011
20110076695IMMUNOASSAY ANALYZER AND IMMUNOASSAY METHOD - The present invention provides an immunoassay analyzer capable of discriminating between normal coloring due to a specific immunoreaction and abnormal coloring due to a cause other than the specific immunoreaction in a measurement region of a sample analysis tool. An immunoassay analyzer 03-31-2011
20110074450Method for Measuring Target Component in Erythrocyte-Containing Specimen - [Object] To provide a method for measuring a target component in an erythrocyte-containing specimen with high reliability while suppressing the influence of the Ht value of the specimen.03-31-2011
20110070633ANALYTICAL TOOL, ANALYTICAL TOOL PACK, CARTRIDGE INCLUDING PLURALITY OF PACKS, METHOD OF MAKING ANALYTICAL TOOL PACK, ANALYZER, AND MECHANISM FOR TAKING OUT OBJECT - The present invention relates to an analytical tool pack (03-24-2011
20110065099METHOD OF PRETREATING SPECIMEN AND IMMUNOASSAY USING THE SAME - The present invention provides a method of pretreating a specimen, which allows measurement according to an immunoassay to be carried out on a specimen from nasal secretion while preventing non-specific reactions. According to this method, the specimen from nasal secretion is treated with a protease beforehand and then an immunoassay is performed. As the protease, it is preferable to use semi-alkaline protease (EC 3.4.21.63). Furthermore, it is preferable that a substance to be pretreated by the pretreatment method according to the present invention is an influenza virus contained in the specimen from nasal secretion. The immunoassay preferably is an immunoagglutination assay. Examples of the immunoagglutination assay include a turbidimetric immunoassay, a latex turbidimetric immunoassay, and a latex agglutination assay that is performed on a slide glass.03-17-2011
20110059483Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - To provide a molecular probe for imaging of pancreatic islets. A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe includes any one of the following polypeptides; polypeptides represented by the following formulae (1), (5), and (9); and polypeptides having homology with the foregoing polypeptides;03-10-2011
20110058995OPTICAL MEASUREMENT APPARATUS - An object is to provide an optical measurement apparatus for performing an efficient test by optical measurement without incurring incorrect measurements.03-10-2011
20110058994TEST INSTRUMENT AND OPTICAL MEASUREMENT APPARATUS - It is an object to provide a test instrument and an optical measurement apparatus which enable easy matching of test results when tests by optical measurement are performed with respect to a large number of patients.03-10-2011
20110058993OPTICAL MEASUREMENT APPARATUS - An optical measurement apparatus is provided for conducting a test by efficiently reading color development of a reagent after reaction by optical measurement.03-10-2011
20110048981Sample collection implement - A sample collection implement S03-03-2011
20110042212ANALYZING TOOL - The present invention relates to an analyzing tool including: a plurality of electrodes 02-24-2011
20110040207ANALYSIS DEVICE - This invention is regard to an analysis device that analyze a specific component in bodily fluid extracted from the skin using an analysis tool. The analysis device comprise a laser beam oscillation section that emits a laser beam for extracting the bodily fluid from the skin, and a detection mechanism that detects whether or not the analysis tool exists at a target position. The analysis device is adapted to emit the laser beam from the laser beam oscillation section when the analysis tool is detected by the detection mechanism.02-17-2011
20110040160ANALYSIS DEVICE HAVING A DISCARDING MECHANISM - An analyzing device which fits an analyzing instrument 02-17-2011
20110038766MICROCHANNEL AND ANALYZING DEVICE - A microchannel 02-17-2011
20110036729CONTROL LIQUID JUDGING METHOD AND ANALYSIS DEVICE - The present invention relates to a method for distinguishing between a sample and a control liquid in a system for analyzing a specific component in the sample by using an analyzing tool having a working electrode and an counter electrode. This discriminating method includes a first step of applying a voltage between the working electrode and the counter electrode, a second step of measuring a response current at certain intervals by use of the working electrode and the counter electrode, a third step of calculating a relative value for a peak value or an end value of the response current, a fourth step of calculating a change rate of the relative value, and a fifth step of distinguishing between the sample and the control liquid based on the change rate.02-17-2011
20110036712ANALYZING SYSTEM - The present invention relates to an analysis system including a laser beam oscillator 02-17-2011
20110033381MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME - A precursor of molecular probe for imaging of pancreatic islets is provided. A polypeptide represented by any one of the following formulae (1) to (4), or a polypeptide having a homology with the foregoing polypeptide.02-10-2011
20110027915METHOD OF PRODUCING INSOLUBLE CARRIER PARTICLES, INSOLUBLE CARRIER PARTICLES, MEASUREMENT REAGENT, SPECIMEN ANALYZING TOOL, AND IMMUNOTURBIDIMETRIC ASSAY - The present invention provides a measurement reagent that is capable of suppressing nonspecific aggregation even when the amount of antibody to be carried is increased, and is capable of measuring in a wide measurement concentration range with high measurement sensitivity; an immunoturbidimetric assay using the same; and a method of producing thereof. A method of producing an insoluble carrier particle of the present invention is a method of producing an insoluble carrier particle carrying an antibody or an antigen on a particle surface thereof. The method includes a sensitization reaction processes in which the antibody or the antigen is brought into contact with the insoluble carrier particle in the presence of an amino acid with a charged polar side chain in a sensitization reaction solution. The insoluble carrier particles obtained by the producing method of the present invention show favorable dispersibility because nonspecific aggregation is suppressed. As can be seen from Examples 1-1 to 1-4 in FIG. 02-03-2011
20110027826LEUKOCYTE ANALYSIS METHOD AND ANALYSIS REAGENT FOR USE IN THE METHOD - The present invention provides a method for analyzing leukocytes, by which the leukocytes can be classified and measured stably with high accuracy even when a dilution ratio of a sample containing the leukocytes is low or a flow velocity during the analysis is slow, and an analysis reagent used for the analysis method. The analysis method of the present invention includes the steps of mixing a sample containing leukocytes and erythrocytes and an analysis reagent containing a surfactant that reacts with leukocytes; and measuring the leukocytes by passing a mixed solution of the sample and the analysis reagent through a fine through-hole, measuring a signal detected when the mixed solution passes through the fine through-hole, and classifying and counting the leukocytes in the sample. The analysis reagent further contains a nonionic surfactant, and the nonionic surfactant has a sugar residue as a hydrophilic region and an aliphatic chain as a hydrophobic region.02-03-2011
20110027129Method for formation of reagent layer in analysis apparatus, method for manufacture of anlalysis apparatus, and analysis apparatus - The present invention relates to a method for forming a reagent layer in an analytical tool including a first step of holding a reagent-containing liquid onto a substrate, and a second step of drying the reagent-containing liquid. A liquid containing a tetraborate as a drying accelerator is used as the reagent-containing liquid. A content of a tetraborate in the reagent-containing liquid is, for example 1 g or more based on 100 mL of the reagent-containing liquid. The tetraborate is, for example, tetrasodium borate or tetrapotassium borate.02-03-2011
20110023635TANK FOR INTRODUCING LIQUID DROP THEREINTO AND ANALYZING DEVICE - A liquid droplet introducing tank 02-03-2011
20110021884MEDICAL DEVICE AND COVER STRUCTURE - A medical device includes a casing, a cover member that covers a portion on one-direction side of the same, and a sheet member interposed therebetween. The cover member includes on its periphery a hook part having a hook-like portion and a protrusion. The casing includes a latch part configured to engage with the hook part and a fitted portion for the protrusion to fit in. The sheet member includes an alignment part for aligning itself with the cover member. The cover member preferably has optical transparency. The casing preferably includes a recess shaped to fit with an outer shape of the cover member at a portion to be covered by the cover member.01-27-2011
20110020943DRY TESTING TOOL, METHOD FOR MEASURING METAL, AND METHOD FOR PRODUCING DRY TESTING TOOL - The present invention provides a dry testing tool with which a metal in the various types of samples such as biological samples, food, and the like can be measured very easily, rapidly, high sensitively, and specifically by a simple colorimetric method and a method for measuring the metal. The dry testing tool of the present invention is a dry testing tool for measuring a metal in a sample, including a porous support and a chelate dye, wherein the chelate dye is bound to the porous support by a hydrophobic bond. The measuring method of the present invention is a method for measuring a metal in a sample, including the steps of: forming a composite of the chelate dye and the metal in the sample by supplying the sample to the porous support to which a chelate dye is bound by a hydrophobic bond; and detecting the metal in the sample using a developed color of the composite.01-27-2011
20110019497FLUID AGITATION METHOD, FLUID AGITATION SYSTEM, AND CARTRIDGE - A fluid agitation method is provided, whereby a swirling flow is generated in a trace amount of fluid, thereby agitating the fluid. The fluid agitation method includes introducing the fluid into an agitation chamber (01-27-2011
20110015391STABILIZER OF COLOR FORMER AND USE THEREOF - The present invention provides a stabilizer that can stabilize a salt of 10-(carboxymethylaminocarbonyn-3,7-bis(dimethylamino)phenothiazine or a derivative thereof even under the existence of moisture or under light irradiation. A compound described in at least one of (1) and (2) below is used as the stabilizer of the salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or the derivative thereof. 01-20-2011
20110005605LIQUID DELIVERY CONTROL METHOD AND LIQUID DELIVERY CONTROL SYSTEM - The present invention provides a liquid delivery control method for delivering a liquid 01-13-2011
20110002813ANALYSIS METHOD, ANALYSIS DEVICE AND PRODUCTION METHOD THEREFOR - The present invention relates to a technique for analyzing the concentration of a specific component in a sample liquid, such as a method for analyzing a sample. The analyzing method includes a first detection step for irradiating light from a light source (01-06-2011
20100323382METHOD FOR ASSAYING BILIRUBIN AND ASSAY INSTRUMENT USED IN BILIRUBIN ASSAY - A method for assaying bilirubin in which a dry reagent is used, which is capable of accelerating the reaction of bilirubin oxidase, and an assay instrument to be used in the method for assaying bilirubin, are provided. The method for assaying bilirubin is characterized in that a biological sample and a bilirubin oxidase-containing dry reagent are mixed first, and then the mixture obtained and a surfactant-containing dry reagent are mixed. An assay instrument (12-23-2010
20100312266PUNCTURE DEVICE - The present invention relates to a puncture device 12-09-2010
20100305597LANCET DEVICE AND PUNCTURE DEVICE - The present invention relates to a lancet device 12-02-2010
20100300898Analysis Tool, Analyzer, Sample Shortage Detection Method, and Sample Analysis Method - There is provided an analysis tool having a plurality of electrodes formed on a substrate. The plurality electrodes include two or more first electrodes having working electrodes and one or more second electrodes having counter electrodes. The analysis tool may also additionally have a flow channel for transferring a sample. The electrodes are preferably disposed so that the working electrodes and the counter electrodes have a symmetrical positional relationship with each other in a transferring direction of the sample in the flow channel.12-02-2010
20100299072SUBSTRATE CONCENTRATION MEASUREMENT METHOD AND SUBSTRATE CONCENTRATION MEASUREMENT APPARATUS - This invention is a method for a substrate concentration measurement method including measuring a concentration of a substrate in a blood specimen containing hemoglobin. In the method, the substrate concentration is calculated by using a measurement value correlating with a substrate concentration influenced by hemoglobin, and a hemoglobin concentration or a value correlating with the hemoglobin concentration. A substrate concentration is calculated by correcting the measurement value Re correlating with the substrate concentration based on the following Formulae 1 and 2: [Formula 1] Corrected value=100×Re/V (%), wherein V (%) represents a value with respect to plasma (a ratio of a measurement value influenced by hemoglobin with respect to a measurement value obtained by measuring plasma), and Re represents the measurement value correlating with the substrate concentration influenced by hemoglobin; [Formula 2] Value with respect to plasma V (%)=(Vmax×Re)/(Km+Re)+B, wherein Vmax represents a value obtained by subtracting an intercept (B) from the value (V) with respect to plasma which is maintained constant even when the measurement value influenced by hemoglobin increases, Km represents a value of Re at which the value V (%) with respect to plasma becomes Vmax/2, and B represents a value (constant) of V (%) with respect to plasma when Re is 0.11-25-2010
20100298856LANCET DEVICE - A lancet device is configured for performing a puncture by mounting a lancet including a puncture needle to the tip of a puncture body holder. The lancet device has a simple configuration that makes it possible to strengthen the retaining force for retaining the lancet when the lancet is used. In the lancet device, an insertion portion of a puncture body that is inserted into a mounting portion of the puncture body holder is retained by means of the frictional force. A fastening member provided in a main body side makes contact with the outer peripheral portion of the mounting portion of the puncture body holder and inwardly fastens the mounting portion when the fastening member is moved in the puncture direction relative to the puncture body holder.11-25-2010
20100297617PRIMER SET FOR AMPLIFYING NAT2 GENE, REAGENT FOR AMPLIFYING NAT2 GENE CONTAINING THE SAME, AND THE USES THEREOF - Primer sets for amplifying target regions containing sites to be detected in the NAT2 gene by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Three pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 7, 33, and 60 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 18, 48 and 81, respectively. The use of these primer sets makes it possible to amplify three target regions including parts where three types of polymorphisms (NAT2*5, NAT2*6, and NAT2*7) of the NAT2 gene are generated, respectively, in the same reaction solution at the same time.11-25-2010
20100292608ANALYSIS INSTRUMENT - An analysis instrument (11-18-2010
20100291691METHOD OF MEASURING GLYCATED HEMOGLOBIN CONCENTRATION AND CONCENTRATION MEASURING APPARATUS - When the concentration of glycated hemoglobin is measured, a plurality of wavelengths are selected as measurement wavelengths from the wavelength range of 400 to 450 nm. Preferably, by use of a liquid chromatography, at least the light of different peak wavelengths in the wavelength range of 415 to 430 nm are continuously or intermittently received to obtain a three dimensional chromatogram having as variables the wavelength, the elution time and the amount of detection. The concentration of glycated hemoglobin is calculated based on this three dimensional chromatogram.11-18-2010
20100288650METHOD FOR MEASURING SUBSTRATE CONCENTRATION AND APPARATUS FOR MEASURING SUBSTRATE CONCENTRATION - This invention provides a substrate concentration measuring method for measuring a concentration of a substrate included in a specimen based on an output for measurement from an enzyme electrode when the enzyme electrode and the substrate are reacted with each other, the substrate concentration is calculated using an output for correction from the enzyme electrode obtained when a reference solution whose substrate concentration is known and the enzyme electrode are reacted with each other before or after the enzyme electrode and the substrate are reacted with each other. For example, the output for correction is measured by each specimen. In this method, the substrate concentration may be calculated using the output for correction for the specimen to be measured and an output for correction corresponding to the at least one other specimen and measured prior to the output for correction.11-18-2010
20100288024DEGASIFIER AND LIQUID CHROMATOGRAPH EQUIPPED THEREWITH - The present invention relates to a deaerator 11-18-2010
20100282854METHOD FOR FORMING OPTICAL READING CODE AND ANALYTICAL TOOL - The method for forming an optical reading code and an analytical tool includes performing pattern formation of a plurality of pits by irradiating a target surface for code formation with a laser in order to form a desired optical reading code. The analytical tool includes a substrate on which a cover is laminated and an optical reading code being formed by pattern formation of a plurality of pits.11-11-2010
20100280789MELTING CURVE ANALYZING METHOD AND MELTING CURVE ANALYZING DEVICE - The present invention provides a melting curve analyzing method that can automatically analyze whether or not a peak is present in at least one of two temperature ranges. A signal differential value (A) having a maximum absolute value is searched for among signal differential values at respective temperatures. When a temperature (t11-04-2010
20100276286ANALYZER - The present invention relates to an analyzing device to be used by inserting an analytical instrument 11-04-2010
20100276285Analysis Tool and Manufacturing Method Thereof - This aims to provide an analyzing tool including a substrate, a first electrode formed on the substrate and having an action pole, a second electrode formed on the substrate and having an opposed pole, and a first regulating element for regulating such a contact area in the action pole as to contact a specimen. The analyzing tool further comprises second regulating elements for regulating the effective area for electron transfers in at least one of the action pole and the opposed pole.11-04-2010
20100274499NUCLEIC ACID AMPLIFICATION DETERMINING METHOD AND NUCLEIC ACID AMPLIFICATION DETERMINING DEVICE - The present invention provides an amplification determining method that can determine whether or not an objective nucleic acid has been amplified with respect to a sample treated so as to amplify the nucleic acid. Signal values showing molten states of the treated sample at respective temperatures are provided, and the maximum signal value (A) is searched for. Further, signal differential values at the respective temperatures are calculated by differentiation of the signal values at two successive points, and second-order differential values of the differential values are calculated by differentiation at four successive points. Among the second differential values, from those in a predetermined temperature range including a Tm value of the objective nucleic acid, the maximum second differential value (D10-28-2010
20100273173METHOD FOR AMPLIFYING TARGET NUCLEIC ACID SEQUENCE AND PROBE USED FOR THE SAME - The present invention provides a method for amplifying a target sequence while suppressing inhibition of an amplification reaction in nucleic acid amplification in the presence of the probe. At the time of amplifying the target sequence, as the probe caused to coexist in amplification of the target sequence, a probe having a base sequence in which a melting temperature of the double-stranded nucleic acid is equal to or lower than a reaction temperature of the elongation reaction is used. In the presence of such a probe, for example, annealing of a primer and an elongation reaction from the primer are hardly inhibited by the presence of the probe so that amplification of the target sequence can be conducted sufficiently. Therefore, when a polymorphism of a target site in the target sequence is analyzed by a Tm analysis or the like, high reliability can be achieved.10-28-2010
20100264942Control Liquid Identifying Method and Analysis Device - Disclosed is a method of distinguishing between a specimen and a control solution in a system for analyzing a specific component within the specimen using an analysis tool. The distinguishing method includes a first step (S10-21-2010
20100261264TEST APPARATUS - A test apparatus is disclosed for measuring a component. The test apparatus maintains the amount of a specimen to be used for a reaction with a reagent at a constant value by allowing all of a fluid specimen to be measured and thus improves the accuracy and reproducibility of a test. The test apparatus includes a solution storage unit capable of holding a solution beforehand or allowing a solution to be filled therein, a capillary having a first end part and a second end part for storing the fluid specimen, and a test piece for measuring the component to be measured in the specimen. The solution storage unit and the second end part of the capillary are communicable with each other, and the first end part of the capillary is placed so as to be in contact with the test piece.10-14-2010
20100259747SAMPLE DETECTOR AND MEASUREMENT DEVICE EQUIPPED WITH THE SAME - A sample detector B includes a member 10-14-2010
20100258440ANALYSIS APPARATUS AND ANALYSIS METHOD FOR CAPILLARY ELECTROPHORESIS - A capillary electrophoresis analysis apparatus is provided for analyzing samples by a capillary electrophoresis method that allows for rapid and highly accurate separation and detection, wherein the apparatus may be used in the diagnosis and/or monitoring of selected diseases.10-14-2010
20100255563CONTAINER AND ANALYSIS CONTAINER USING THE SAME - A vessel, which can easily be opened and closed without detaching and attaching a cover, is provided. The vessel of the present invention includes a vessel body 10-07-2010
20100244862Analysis Tool - The present invention relates to an analysis tool including a reagent portion and electrodes. The electrodes include a porous conductive portion where the reagent portion is formed. The porous conductive section is formed by, for instance, coating at least a part of a surface and an inner surface of a porous body with a conductive film. The porous body is, for instance, an insulating fiber mesh cloth. Preferably, the electrodes are formed in a sheet shape.09-30-2010
20100243901PELLET FOR USE IN SPECTROMETRY, METHOD OF PREPARING THE SAME, AND METHOD OF SPECTROMETRY09-30-2010
20100240603EXPRESSION INHIBITOR OF NUCLEAR TRANSCRIPTION FACTOR AP-1 AND PHARMACEUTICALS AND PRODUCTS USING THE SAME - An expression inhibitor of a nuclear transcription factor AP-1 is provided that is excellent in safety and activity of inhibiting the expression of a nuclear transcription factor AP-1. The AP-1 expression inhibitor of the present invention is characterized by containing chamaemeloside. In the present invention, chamaemeloside may be contained as an extract of Roman chamomile or German chamomile. The chamaemeloside is contained in Roman chamomile or German chamomile. Conventionally, Roman chamomile and German chamomile have been used as cosmetic materials and herb teas and have no problems in safety. An extract of Roman chamomile or German chamomile and chamaemeloside inhibit the expression of the AP-1 at the gene level (see FIG. 09-23-2010
20100240150MEASURING REAGENT AND TURBIDIMETRIC IMMUNOASSAY AND SAMPLE ANALYSIS TOOL USING THE SAME - A measuring reagent is provided that allows the amounts of insoluble carrier particles and monoclonal antibodies to be reduced, can improve measurement sensitivity with respect to an object to be measured in a low concentration range, allows the object to be measured in a wide concentration range, and is used for a turbidimetric immunoassay applicable to a sample analysis tool such as a test piece. The measuring reagent includes two types of insoluble carrier particle groups that are different in mean particle size from each other. The insoluble carrier particles contained in one insoluble carrier particle group support polyclonal antibodies and monoclonal antibodies, and the insoluble carrier particles contained in the other insoluble carrier particle group support at least one of the polyclonal antibodies and the monoclonal antibodies. Preferably, the former is an insoluble carrier particle group with a small mean particle size and the latter is an insoluble carrier particle group with a large mean particle size.09-23-2010
20100217095MEDICAL DEVICE - In a medical device that measures a condition of a living body, a first recess is formed on the exterior (first and second surfaces) of its casing. An anti-slip member is attached to the inside of the first recess. Moreover, another recess (second recess) is provided inside the first recess. The second recess is formed such that an end of the second recess protrudes from the anti-slip member when the anti-slip member is attached to the inside of the first recess. In the case where a display screen that displays a measurement result is provided on the casing, it is preferable that the first and second surfaces are adjacent to a third surface on which the display screen is provided.08-26-2010
20100216123METHOD OF DETECTING MUTATION AND KIT USED IN THE SAME - A method of detecting a mutation is provided that uses Tm analysis and is excellent in detection sensitivity. A detection probe consisting of a polynucleotide complementary to a sequence to be detected containing a detection site that has been mutated and an inhibitory polynucleotide complementary to a sequence not to be detected containing the detection site that is unmutated are added to a sample containing a DNA to be detected in which the detection site has been mutated and a DNA not to be detected in which the detection site is unmutated, so that the detection probe is hybridized with the DNA. Then while the hybridization product between the DNA and the detection probe is heated, a signal variation associated with an increase in temperature is measured, then the signal variation is analyzed, and thereby a Tm value is determined, based on which the presence of the mutation is determined.08-26-2010
20100209964METHOD AND APPARATUS FOR ANALYZING SAMPLE - A method for analyzing a sample includes the step of irradiating a reaction portion of a sample BL and a reagent 08-19-2010
20100196201CARTRIDGE AND ANALYZING SYSTEM - The present invention relates to a cartridge 08-05-2010
20100190194POSTPRANDIAL HYPERGLYCEMIA MARKER, METHOD OF MEASURING THE SAME, AND USAGE THEREOF - A new method of diagnosing postprandial hyperglycemia by indirectly measuring a blood glucose level is provided. Postprandial hyperglycemia is detected by measuring a glycation degree of lysine in hemoglobin, in which a side chain amino group of lysine is glycated (GHbLys %). Measurement of GHbLys % can be performed by cleaving hemoglobin by protease, treating a glycated part of a lysine residue in the obtained cleavage product of hemoglobin with fructosyl amino acid oxidase, and measuring a redox reaction between the glycated part and fructosyl amino acid oxidase.07-29-2010
20100187110PROCESS FOR ANALYZING SAMPLE BY CAPILLARY ELECTROPHORESIS METHOD - A process for analyzing a sample by a capillary electrophoresis method is provided that allows the apparatus to be reduced in size, allows a high analytical precision to be obtained, and can be carried out easily. The analytical process of the present invention is a process for analyzing a sample by a capillary electrophoresis method. The analytical process includes preparing a capillary tube to be used for the capillary electrophoresis method, and performing electrophoretic separation of a complex of a sample and an anionic group-containing compound that are bonded together, in the capillary tube, wherein the capillary tube includes an anionic layer that is formed of the anionic group-containing compound and that is coated on the inner wall of the capillary tube, and the anionic layer is fixed to the inner wall of the capillary tube by a covalent bond.07-29-2010
20100187107Enzyme electrode - The present invention relates to an enzyme electrode including: a carbon particle; a metal particle held on the carbon particle, the metal particle having a catalytic activity against a redox reaction; a redox enzyme. The enzyme electrode of the present invention further includes a high-resistance particle enhancing an electrical resistance, the high-resistance particle being chemically stable. The high-resistance particle contains an inorganic substance, for example. The inorganic substance is aluminum oxide or smectite, for example.07-29-2010
20100181199ANALYSIS APPARATUS FOR CAPILLARY ELECTROPHORESIS - A capillary electrophoresis analysis apparatus is provided for analyzing samples by a capillary electrophoresis method that allows for rapid and highly accurate separation and detection.07-22-2010
20100178659METHOD OF MEASURING HbA1c - A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be maintained. Whole blood is stored in a presence of a glycolytic inhibitor and protease is added to the stored whole blood sample to cleave hemoglobin in the whole blood sample. Then a glycated part of a hemoglobin fragment thereby obtained is treated with fructosyl amine oxidase. Thereafter, a glycation degree of HbA1c is determined by measuring a redox reaction between the glycated part and the fructosyl amine oxidase. Further, instead of storage of the whole blood in a presence of the glycolytic inhibitor, a strong electrolyte substance such as KCl, K07-15-2010
20100175996PROCESS FOR ANALYZING SAMPLE BY CAPILLARY ELECTROPHORESIS METHOD - A process for analyzing a sample by a capillary electrophoresis method is provided that allows the apparatus to be reduced in size, allows a high analytical precision to be obtained, and can be carried out easily. The analytical process of the present invention is a process for analyzing a sample by a capillary electrophoresis method. The process includes a step of preparing a capillary channel to be used for the capillary electrophoresis method and a step of electrophoresing a complex of a sample and an anionic group-containing compound that are bonded together, in the capillary channel, wherein the capillary channel includes an A layer that is coated on an inner wall thereof and a B layer that is coated on the A layer.07-15-2010
20100173299MUTANT NUCLEIC ACID RELATED TO CHRONIC MYELOPROLIFERATIVE DISORDER AND METHOD OF EVALUATING CHRONIC MYELOPROLIFERATIVE DISORDER - A new mutant gene related to the onset of CMPD, particularly, the new mutant gene related to the onset of CMPD in patients who develop CMPD despite of JAK207-08-2010
20100168526MEDICAL DEVICE - In a medical device that measures a condition of a living body, a recess is formed on the exterior (first and second surfaces) of its casing. An attachment member is attached to the inside of the recess. In the case where a display screen that displays a measurement result is provided on the casing, it is preferable that the first and second surfaces are adjacent to a third surface on which the display screen is provided. Preferably, the attachment member includes an adhesive material layer, a print layer, and an anti-slip layer that is formed of at least one of a resin material and a rubber material, and the adhesive material layer, the print layer, and the anti-slip layer are stacked in sequence.07-01-2010
20100160741MEDICAL DEVICE - A medical device measures a condition of a living body. The medical device includes a main body containing a measuring device inside, and a sheet member. The sheet member displays information on a user on one principal surface, with the other principal surface being attached to an outer surface of the main body. The sheet member may include a sheet-like base, a protective layer formed on one principal surface of the base, and an adhesive material layer formed on the other principal surface of the base. At this time, it is preferable that the protective layer is formed of a material having optical transparency, and that the information on the user is displayed on the one principal surface of the base.06-24-2010
20100155242Method of Analyzing a Sample by Capillary Electrophoresis - The present invention is directed to the described capillary electrophoresis apparatus and methods of using such apparatus for separating and analyzing components of a sample.06-24-2010
20100137697MEASUREMENT DEVICE - A measurement device A includes a display section 06-03-2010
20100128262Analyzer Having Light Shield - The invention relates to an analyzing apparatus including an installation portion having an insertion port 05-27-2010
20100117675LIQUID CRYSTAL DISPLAY DEVICE AND ANALYSIS DEVICE INCLUDING THE SAME - In order to provide a liquid crystal display device which can detect a defective indication due to short circuit which occurs between a common electrode and a counter electrode by a conductive impurity enters into a liquid crystal display panel, and an analysis device including the same, a blood glucose meter includes a display section and a microcomputer. For performing an inspection for a defective indication on a liquid crystal display panel of the display section, the microcomputer uses ports as input/output ports for a defective indication inspection. The microcomputer detects whether an inspection signal sent from the port can be received at the other port or not to perform the inspection for a defective indication.05-13-2010
20100116660Electrophoresis Chip, Electrophoresis Apparatus, and Method for Analyzing Sample by Capillary Electrophoresis - An electrophoresis chip that can be small and simple and that can analyze a sample with high accuracy is provided. The electrophoresis chip includes an upper substrate 05-13-2010
20100112622METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN - The present invention provides a phenothiazine-derivative color-measuring method that can detect a phenothiazine-derivative color even at a wavelength longer than the wavelength that exhibits maximum absorption. A phenothiazine-derivative color is detected, by adding a 5-hydroxy-1-(4-sulfophenyl)-4-(4-sulfophenylazo)pyrazole-3-carboxylic acid salt, 6-hydroxy-5-(4-sulfophenylazo)-2-naphthalenesulfonic acid salt, 3-hydroxy-4-(4-sulfonaphthylazo)-2,7-naphthalenedisulfonic acid salt, 7-hydroxy-8-(4-sulfonaphthylazo)-1,3-naphthalenedisulfonic acid salt, 3′,6′-dihydroxy-2′,4′,5′,7′-tetraiodospiro[isobenzofuran-1(3H),9′-(9H)xanthene]-3-one salt, 3′,6′-dihydroxy-2′,4′,5′,7′-tetrabromo-4,5,6,7,-tetrachlorospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-3-one salt, 4,5,6,7-tetrachloro-3′,6′-dihydroxy-2′,4′,5′,7′-tetraiodospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-3-one salt or flavonoid-based color to the reaction system containing a phenothiazine-derivative color, and then measuring the light absorbance at a wavelength of 610 to 730 nm.05-06-2010
20100112559PRIMER SET FOR AMPLIFYING OBESITY GENE, REAGENT FOR AMPLIFYING OBESITY GENE CONTAINING THE SAME, AND THE USES THEREOF - Primer sets for amplifying target regions containing sites to be detected in the obesity gene (the β2AR gene, the β3AR gene, and the UCP1 gene) by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Three pairs of primer sets are used including forward primers composed of the base sequences of SEQ ID NO: 9 or SEQ ID NO: 109, SEQ ID NO: 25, and SEQ ID NO:43 as well as reverse primers composed of the base sequences of SEQ ID NO: 18, SEQ ID NO: 30, and SEQ ID NO: 63, respectively. The use of these primer sets makes it possible to specifically amplify a target region including a site where a polymorphism to be detected is generated in the β2AR gene, the β3AR gene, and the UCP1 gene, in the same reaction solution at the same time.05-06-2010
20100108887PELLET FOR SPECTROMETRY, PROCESS FOR PRODUCING THE PELLET, AND METHOD FOR SPECTROMETRY USING THE PELLET - A pellet used for spectrometry is manufactured by, for example, mixing polyethylene powder having an average particle size not greater than 35 μm with powder of an analysis target, and compressing the mixture. A sample pellet (B) prepared by compacting only polyethylene powder having an average particle size not grater than 35 μm exhibits a high transmittance in the wave number range of 10-340 cm05-06-2010
20100108520ELECTROPHORESIS CHIP AND ELECTROPHORESIS UNIT HAVING THE SAME - In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contrast and decrease in resolution, an electrophoresis chip is provided with a sample introduction groove, an electrophoresis groove, and a through hole. The sample introduction groove, the electrophoresis groove, and the through hole are formed on different substrates. In the electrophoresis chip, by combining the substrates, the sample introduction groove and the electrophoresis groove are located in different planes.05-06-2010
20100108518ELECTROPHORESIS CHIP AND ELECTROPHORESIS UNIT HAVING THE SAME - In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contrast and decrease in resolution, an electrophoresis chip is provided with a sample introduction groove, an electrophoresis groove, and a through hole. The sample introduction groove, the electrophoresis groove, and the through hole are formed on different substrates. In the electrophoresis chip, by combining the substrates, the sample introduction groove and the electrophoresis groove are located in different planes.05-06-2010
20100099125METHOD FOR MEASURING LOW-DENSITY LIPOPROTEIN (LDL) CHOLESTEROL AND TEST PIECE FOR MEASURING LDL CHOLESTEROL - An LDL cholesterol measurement method that can be used with a test piece is provided. The LDL cholesterol measurement method for measuring LDL cholesterol in a sample has (A) a step of providing a total-cholesterol measurement portion and a non-LDL cholesterol measurement portion for measuring non-LDL cholesterol, which is cholesterol other than LDL cholesterol; (B) a step of measuring the total cholesterol in the sample in the total-cholesterol measurement portion; (C) a step of measuring the non-LDL cholesterol in the sample in the non-LDL cholesterol measurement portion; and (D) a step of obtaining the LDL cholesterol level in the sample by subtracting the non-LDL cholesterol value measured in the step (C) from the total-cholesterol value measured in the step (B).04-22-2010
20100086989MUTANT GLUCOSE DEHYDROGENASE - A mutant glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 3 or an amino acid sequence of SEQ ID NO: 3 including substitution, deletion, insertion or addition of one or more amino acid residues other than the amino acid residue at the 365th position and having glucose dehydrogenase activity, wherein an amino acid residue at a position corresponding to the 365th position of, the amino acid sequence is replaced with another amino acid residue, and the mutant glucose dehydrogenase shows an improved substrate specificity to glucose.04-08-2010
20100075426CARTRIDGE, RESIDUAL LIQUID REMOVING METHOD, AND AUTOMATIC ANALYZER - A cartridge is provided that can remove a residual liquid all around the leading end of a pipette, without requiring any new equipment, regardless of the viscosity of the residual liquid. This cartridge includes a plurality of tanks, each of which has an upper opening, and a liquid is introduced into or led out from at least one of the plurality of tanks 03-25-2010
20100068713PROBE FOR DETECTING MUTATION IN JAK2 GENE AND USE THEREOF - A probe for detecting a mutation in the JAK2 gene is provided that can detect a target sequence containing a mutation even when the target sequence containing the mutation and a non-target sequence containing no mutation coexist, which are different only in a single base from each other. The probe to be used is an oligonucleotide that is at least one oligonucleotide having a sequence identical to that of a region extending from a cytosine base (C) at position 84 to be considered as the first base to any one of the 17th to 22nd bases in the direction toward the 5′ end in exon 12 of the JAK2 gene consisting of the base sequence of SEQ ID NO: 1, with the cytosine base (C) being the 3′ end. Even in the case of a sample containing both the JAK2 genes with a mutation that has occurred and without a mutation that has occurred, the use of such a probe in, for example, Tm analysis allows the former mutation to be detected. Preferably, the probe is labeled with a fluorescent dye.03-18-2010
20100054992SPECIMEN SUPPLYING TOOL AND SPECIMEN ANALYSING INSTRUMENT USING THE SAME - A specimen supplying tool in which structure is simple, and a liquid specimen and air bubbles do not remain within a through-bore for introduction of a specimen, is provided. The specimen supplying tool includes a substrate 03-04-2010
20100051464ANALYSIS CHIP AND ANALYSIS APPARATUS - An analysis chip that enables an apparatus to be small, analysis to be simple, analysis time to be short and analysis of both glycosylated hemoglobin and glucose to be highly accurate is provided. The electrophoresis chip includes an upper substrate 03-04-2010
20100051456ANALYSIS IMPLEMENT WITH OPENING IN INSULATION FILM - The present invention relates to an analytical tool (X) which includes a substrate (03-04-2010
20100047806PROBES FOR DETECTING IMMUNE-RELATED GENE POLYMORPHISMS AND APPLICATIONS OF THE SAME - Polymorphism detection probes that can distinguish polymorphisms that have only one different base are provided. At least one oligonucleotide selected from the group consisting of the oligonucleotides of SEQ ID NOS. 4, 23, 30, 47, 57 and 64 is used as a probe in a Tm analysis. A Tm analysis using such probes allows easy detection of specific polymorphisms of the FCGR3A gene, the FCGR2A gene, the IL-10 gene, the TNF α gene and the TNF 8 gene that have an effect on the pharmaceutical effects of antibody drugs or the like. Moreover, such probes allow detection of two or more types of polymorphisms in a single reaction system by introducing two or more types of the probes concomitantly.02-25-2010
20100036281Integrated Sensor and Lancet Device and Method for Collecting Body Fluid Using the Same - The present invention relates to a sensor/lancet integrated device 02-11-2010
20100032297Electrophoresis Chip and Electrophoresis Apparatus - An electrophoresis chip that enables an apparatus to be small, analysis time to be short and glycosylated hemoglobin to be analyzed highly accurately is provided. The electrophoresis chip includes an upper substrate 02-11-2010
20100032294METHOD FOR ANALYZING HEMOGLOBIN BY CAPILLARY ELECTROPHORESIS AND ADDITIVE USED THEREIN - The present invention provides a method for analyzing hemoglobin by capillary electrophoresis, that allows the apparatus to be smaller in size, allows a highly precise analysis to be obtained, and allows the analysis to be performed in a short period of time. The analytical method of the present invention are methods for analyzing hemoglobin by capillary electrophoresis, comprising: a sample-providing step of providing a sample containing hemoglobin; a capillary tube-providing step of providing a capillary tube containing a buffer solution; and an electrophoresis step of carrying out electrophoresis of the sample, by introducing the sample into the buffer solution in the capillary tube, and applying a voltage across both ends of the capillary tube; wherein the electrophoresis is carried out following at least one of modes (A) and (B) below: (A) the electrophoresis is carried out with a surfactant (a) added to the buffer solution, the surfactant (a) being a non-ionic surfactant having an alkyl group as a hydrophobic portion and a sugar as a hydrophilic portion; and (B) the electrophoresis is carried out with a surfactant (b) added to the sample, the surfactant (b) being a betaine-type amphoteric surfactant.02-11-2010
20100021600FLAVOR IMPROVING AGENT FOR FOOD AND BEVERAGE - A flavor improving agent using material that has dietary history, i.e. material that has been eaten as food is provided, wherein the flavor improving agent suppresses peculiar smell of food and beverage. A composition containing extract from at least one plant selected from the group consisting of genus 01-28-2010
20100014085Method for Automatically Discriminating Control Solution - The present invention relates to a method for automatically discriminating a control solution from a sample in a measurement system for measuring a target ingredient in the sample by using a measurement wavelength and a reference wavelength, wherein as the control solution, a control solution having a response value lower than a lower limit value (threshold) of a response value, such as absorbance, supposed when luminance of the sample is measured at the reference wavelength and having a response value higher than an upper limit value (threshold) of a response value supposed when luminance of the sample is measured at the detection wavelength for detecting whether the sample is supplied is used.01-21-2010
20100009016DEHYDROEPIANDROSTERONE PRODUCTION PROMOTER AND USE THEREOF - A new orally administerable DHEA production promoter is provided. A composition containing an extract of at least one selected from the group consisting of plants of 01-14-2010
20090325315DETECTION METHOD OF TARGET SUBSTANCE, DETECTION REAGENT USED FOR THE SAME, AND THE USES THEREOF - A new detection method, for detecting a target substance using formation of an aggregate due to binding of a target substance and a binding substance that binds thereto, that is excellent in detection accuracy, and sensitivity, and a new detection reagent used for the same are provided. Modifying substances having a maximum diameter of about 50 nm or less bind to a binding substance that binds to a target substance, and a modified binding substance is prepared as a binding reagent. A target substance in a sample is detected by bringing this modified binding reagent into contact with the sample, and optically detecting an aggregate that is formed by binding of the modified binding substance and the target substance in the sample. Preferably, the modifying substance includes biotin or a biotin derivative and further includes avidin or an avidin derivative, and the avidin or the avidin derivative binds to the biotin or the biotin derivative. Further, preferably, the biotin or the biotin derivative binds to the binding substance via a spacer.12-31-2009
20090317912Method of Measuring Glycated Hemoglobin Concentration - The present invention relates to a method and an apparatus that measure the concentration of glycated hemoglobin by an optical technique. A wavelength in which the molecular extinction coefficient of oxyhemoglobin agrees or substantially agrees with the molecular extinction coefficient of deoxyhemoglobin is adopted as a measurement wavelength. Preferably, the measurement wavelength is set at from 417 to 421 nm. In the present invention, the concentration of glycated hemoglobin is measured by making use of column chromatography and of using a sample prepared from red blood cells in blood.12-24-2009
20090311797ANALYSIS METHOD AND ANALYSIS APPARATUS - An analysis method includes the steps of causing a moist sample to react with a reagent and measuring concentration of a particular component contained in the sample based on the state after the reaction of the sample with the reagent. The reaction step and the measurement step are performed while the amount of moisture contained in the air in a space accommodating the sample and the reagent is directly or indirectly measured. The method further includes the step of correcting the measurement result of the concentration of the particular component based on the amount of moisture contained in the air.12-17-2009
20090311770Method of collecting microorganisms using fine particles, method of collecting nucleic acids using fine particles, and kits for use in the these methods - The present invention provides a method of collecting microorganisms and a method of collecting nucleic acids, which both can be carried out easily and can achieve a high collection rate. A method of collecting microorganisms according to the present invention includes a microorganism adsorption step of bringing a sample into contact with fine particles so as to cause microorganisms contained in the sample to be adsorbed onto the fine particles. In this method, the fine particles have a particle diameter of 6 μm or less and a specific surface area of 50 m12-17-2009
20090306696Lancet - The present invention relates to a lancet 12-10-2009
20090304550ANALYTICAL TOOL - The present invention relates to an analytical tool (12-10-2009
20090297402ANALYZING INSTRUMENT, TEMPERATURE CONTROL METHOD FOR LIQUID IN ANALYZING INSTRUMENT, AND ANALYZING APPARATUS - This invention relates to a technique for adjusting the temperature of a liquid held on an analyzing instrument (12-03-2009
20090275119Liquid Chromatograph - The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator 11-05-2009
20090269756PRIMER SET FOR AMPLIFYING CYP2C19 GENE, REAGENT FOR AMPLIFYING CYP2C19 GENE CONTAINING THE SAME, AND THE USES THEREOF - Primer sets for amplifying target regions containing sites to be detected in the CYP2C19 gene by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Two pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 12 and 32 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 22 and 48, respectively. The use of these primer sets makes it possible to amplify two target regions including parts where two types of polymorphisms (CYP2C19*2 and CYP2C19*3) of the CYP2C19 gene are generated, respectively, in the same reaction solution at the same time.10-29-2009
20090269754METHOD OF PRODUCING AMPLIFICATION PRODUCT BY PCR AND USAGE THEREOF - A method of producing a PCR amplification product is provided that suppresses an effect of precipitate, turbidity, or the like derived from a whole blood sample on a detection in the detection of an amplified nucleic acid by an optical unit. The amplification product complementary to a target nucleic acid in the whole blood sample is produced by PCR in a condition where a ratio of the whole blood sample in a PCR reaction solution is in the range of 0.1 to 0.9% by volume or 0.01 to 1.8 g/L in term of hemoglobin content. When the PCR is carried out with such conditions, even with an untreated whole blood sample, a monitoring of the amplification product by the optical unit can be done while suppressing the effect of the precipitate or the turbidity.10-29-2009
20090236248Case Unit - A case unit C09-24-2009
20090233322COLORIMETRIC METHOD AND REAGENT USED FOR THE SAME - The present invention provides a colorimetric method that can perform a simple and reliable analysis in a short time. The method includes transferring an electron from an analyte to a coloring reagent that produces color by reduction via a mediator by using an oxidoreductase; and performing qualitative or quantitative analysis of the analyte by measuring color produced in the coloring reagent. The enzyme reaction of this method is a single stage reaction, and the color production reaction occurs via the mediator. Therefore, the measurement can be performed in a short time. Since this reaction requires neither hydrogen peroxide nor oxygen, the measured values are highly reliable.09-17-2009
20090233288PRIMER SET FOR GENE AMPLIFICATION, REAGENT FOR GENE AMPLIFICATION INCLUDING THE SAME, AND USES THEREOF - Primer sets for amplifying two genes (the CYP2C9 gene and the VKORC1 gene) by a gene amplification method are provided, wherein the primer sets can amplify respective target regions of the two genes specifically and efficiently in the same reaction system simultaneously. Two pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 5 and 29 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 18 and 38, respectively. The use of these primer sets makes it possible to specifically amplify target regions including sites where polymorphisms to be detected are generated in the CYP2C9 gene and the VKORC1 gene, in the same reaction solution simultaneously.09-17-2009
20090216259Insertion Needle and Lancet With the Same - The present invention relates to a puncture needle (08-27-2009
20090215026METHOD FOR STORING TETRAZOLIUM COMPOUND, STABILIZER USED IN THE SAME, AND TETRAZOLIUM COMPOUND REAGENT SOLUTION USING THE METHOD - A method for storing a tetrazolium compound stably is provided. The tetrazolium compound is stored in the presence of sodium azide. The tetrazolium compound (A) and the sodium azide (B) are present at a ratio (A:B) in the range from 1:0.02 to 1:6.2. Furthermore, when the tetrazolium compound is stored as a solution, the concentration of the sodium azide is in the range from 0.08 to 3.2 mmol/L and the concentration of the tetrazolium compound is in the range from 0.5 to 8 mmol/L. As the tetrazolium compound, it is preferable to use 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt.08-27-2009
20090208954PRIMER SET FOR AMPLIFICATION OF UGT1A1 GENE, REAGENT FOR AMPLIFICATION OF UGT1A1 GENE CONTAINING THE SAME, AND THE USES THEREOF - Primer sets for amplifying target regions containing sites to be detected in the UGT1A1 gene by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Three pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 4 or 81, 21, and 42 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 13 or 91, 29 and 48, respectively. The use of these primer sets makes it possible to amplify three target regions including parts where three types of polymorphisms (UGT1A1*6, UGT1A1*27, and UGT1A1*28) of the UGT1A1 gene are generated, respectively, in the same reaction solution at the same time.08-20-2009
20090200166Method of Analyzing Hemoglobin by Capillary Eletrophoresis - The present invention is directed to methods of analyzing hemoglobin by capillary electrophoresis involving electrophoresing a hemoglobin-containing sample in the presence of chaotropic anion.08-13-2009
20090177067Glucose Sensor and Glucose Level Measuring Apparatus - The present invention relates to a glucose sensor (07-09-2009
20090176231PROBE FOR DETECTING ABL GENE MUTATION AND USES THEREOF - Detection probes are provided that are capable of detecting a sequence to be detected containing a mutation even when a sequence not to be detected containing no mutation coexists with the sequence to be detected containing a mutation, which are different only in a single base from each other. At least one oligonucleotide selected from the group consisting of SEQ ID NOs: 2˜16 is used as a probe. Even in a sample containing an abl gene in which a mutation has occurred and an abl gene in which no mutation has occurred, the use of such probes in, for example, Tm analysis allows the mutation to be detected.07-09-2009
20090171246Method and Implement for Opening Hole in Soft Material - An hole-opening implement (07-02-2009
20090151792Liquid Feeding Method and Cartridge To Be Used Therein - A liquid feeding method for feeding liquid in a minute flow path is provided. The minute flow path includes flow paths 06-18-2009
20090145840BLOOD CELL SEPARATION MEMBRANE AND BLOOD RETENTION TOOL USING THE SAME - The present invention provides a blood cell separation membrane for separating blood into serum or plasma and blood cells while preventing hemolysis of the blood cells. Such a blood cell separation membrane can be obtained by impregnating a porous membrane for separating blood cells from blood supplied thereto with a solution containing a hydrophobic aminocarboxylic acid, a protein derived from silk, Tris, TES, ε-aminohexanoic acid, tranexanmic acid, or heparin and then drying the membrane.06-11-2009
20090142787Albumin Denaturing Agent - An albumin denaturing agent for digesting an albumin by a protease efficiently is provided. The albumin denaturing agent contains quaternary ammonium having a hydrocarbon group with a carbon number of 12 or more, or a salt of the quaternary ammonium. The albumin in a sample is digested by the protease in the presence of the albumin denaturing agent, a glycated part of the thus obtained albumin digestion product and a FAOD effect a reaction, and a redox reaction between the glycated part and the FAOD is measured, thereby determining a ratio (GA (%)) of the glycated albumin of the glycated albumin with respect to the albumin.06-04-2009
20090124931LANCING UNIT AND LANCING APPARATUS - A lancing unit (U05-14-2009
20090120806Method for Detecting Sample Supply Condition, and Analyzer - The present invention relates to an analytical tool 05-14-2009
20090118361SUPPRESSOR OF EXPRESSION OF MCP-1, AND AMELIORATING AGENT FOR INFLAMMATORY DISEASE, PHARMACEUTICAL, SUPPLEMENT, FOOD, BEVERAGE OR FOOD ADDITIVE USING THE SUPPRESSOR - A suppressor of the expression of MCP-1 is provided that is excellent in safety and is widely applicable to, for example, foods. The suppressor of the expression of MCP-1 according to the present invention is characterized by containing auraptene. Auraptene is contained in citrus fruits such as Hassaku, Amanatsu, Natsumikan, and grapefruit. Since these citrus fruits have been eaten for a long time, the present invention has no problem in safety. Furthermore, even when added to, for example, foods, auraptene does not impair the flavor thereof because it is substantially tasteless and odorless. Since auraptene has a low calorific value, for example, an obese person or a diabetic patient can ingest it over a long period of time. Auraptene suppresses the expression of MCP-1 at a genetic level (see FIG. 05-07-2009
20090114673Dispensing unit for measuring articles - A measuring instrument (A) includes: a storage (05-07-2009
20090113980METHOD OF VERIFYING PERFORMANCE OF OPTICAL DETECTION APPARATUS AND STANDARD REAGENT USED THEREFOR - A method is provided in which with respect to an optical detection apparatus including an optical detection unit and a temperature control unit, whether optical signal detection and temperature control are performed accurately, i.e. the performance thereof, can be verified simply with high reliability. With respect to an optical detection apparatus including an optical detection unit for detecting an optical signal of a sample and a temperature control unit for controlling temperature of the sample, the optical signal detection performance and temperature control performance are verified by the following method. First, a standard sample containing a nucleic acid sequence and a strand complementary thereto that have a known optical signal intensity and Tm value is provided, the temperature of the standard sample is increased or decreased with the temperature control unit, and optical signal intensity of the standard sample is measured with the detection unit. On the other hand, the melting temperature of the standard sample is determined from a change in the optical signal intensity accompanying a change in the temperature. The measured optical signal intensity and melting temperature of the standard sample are compared to the known optical signal intensity and melting temperature of the standard sample, respectively, and thereby it is verified whether the optical signal detection performance of the detection unit and the temperature control performance of the temperature control unit are accurate.05-07-2009
20090109433ANALYZER - An analyzer in which optical measurement is performed with respect to a sample placed in optically transparent cells of an analysis tool includes a light source unit, a light-receiving unit, a tray on which the tool is placed, and a drive mechanism for driving the tray. The tray includes a holding section that holds the tool in a predetermined position. The drive mechanism reciprocates the tray between a first position where the tool placed on the tray is exposed to the outside of the analyzer and a second position where the tool is accommodated inside the analyzer. The light source unit is disposed so that emitted light is incident on a cell of the tool when the tray is located in the second position. The light-receiving unit is disposed so as to receive light transmitted through the cell when the tray is located in the second position.04-30-2009
20090104616PRIMER SET FOR AMPLIFYING SULT1A1 GENE, REAGENT FOR AMPLIFYING SULT1A1 GENE CONTAINING THE SAME, AND THE USES THEREOF - A primer set for amplifying a region including sites to be detected of SULT1A1*2 and SULT1A1*3 in the SULT1A1 gene by a gene amplification method is provided, wherein the primer set can amplify the region specifically. A pair of primer set is used including a forward primer consisting of the base sequence of SEQ ID NO: 7 as well as a reverse primer consisting of the base sequence of SEQ ID NO: 18. The use of this primer set makes it possible to specifically and efficiently amplify, a region including both sites where two types of polymorphisms (SULT1A1*2 and SULT1A1*3) of the SULT1A1 gene are generated.04-23-2009
20090101499Protein-Immobilized membrane, method for immobilization of protein, enzyme-immobilized electrode, and biosensor - The present invention relates to a protein-immobilized membrane (04-23-2009
20090100915Method of Sampling Specimen, Test Method and Dropping Pipette and Specimen Sampler to be Used Therein - A method for taking a sample according to the present invention includes the steps of drawing blood B04-23-2009
20090093832LANCET DEVICE - A lancet device includes a shot prevention mechanism for preventing re-shooting using a used lancet, that inhibits movement to a shot-ready completion state where a puncture body is held at different positions within a casing before and after use. A holding position of the puncture body within the casing before use is different than a holding position after use. When the used lancet is fitted to a main body, a stopper plate does not operate, and a setting release button remains in a depressed state and does not pushed up.04-09-2009
20090088787LANCET AND LANCING APPARATUS - The present invention provides a lancet (X04-02-2009
20090081718Protein cleavage method and thereof - The present invention provides a method for cleaving a glycated protein to obtain an amino acid or a peptide efficiently with a protease. By treating the glycated protein with the protease in the presence of a compound represented by R—X, the amino acid or the peptide is obtained by the cleavage. The R represents an alkyl compound with a carbon number of 9 or more, and preferably is straight-chain alkyl or straight-chain acyl with a carbon number of 9 to 16, branched-chain alkyl or branched-chain acyl with a carbon number of 10 to 40 and a main-chain carbon number of 9 to 16, or straight-chain alkyl that is substituted by cycloalkyl (a carbon number of the cycloalkyl ranges from 3 to 8, and a carbon number of the straight chain ranges from 4 to 13), where X is a sugar residue. Moreover, the glycated protein is, for example, glycated hemoglobin, and preferably β-chain N-terminal amino acid or a β-chain N-terminal peptide is cleaved by the protease treatment.03-26-2009
20090074617SENSOR CARTRIDGE, SENSOR FEEDER, AND MEASURING INSTRUMENT - A sensor cartridge (03-19-2009
20090053823Liquid Reagent of Color Former and Method of Stabilizing The Same - A liquid reagent in which a methylene blue compound color former is stably stored in a liquid state; and a method of stabilizing a methylene blue compound color former in a liquid state. A methylene blue compound color former is stabilized by causing it to coexist with either a quaternary ammonium compound having a C02-26-2009
20090036916LANCET DEVICE - A lancet device includes a puncture needle that receives a biasing force applied by a coil spring and is projected toward the tip side, and is retracted by the biasing force applied by a return spring. In the lancet device a colliding part and the a collision receiving part are made to collide when the puncture needle is projected, and an abutting stopping member elastically deforms. The colliding part is a part of the lancet holder that holds a puncture needle. The collision receiving part is a part of the abutting stopping member. The contact part of the abutting stopping member moves in the direction of the colliding part and comes into contact with the colliding part by the elastic deformation of this abutting stopping member, and the force that retracts the lancet holder is weakened.02-05-2009
20090031829Analyzer - The present invention relates to an analytical tool including a plurality of flow paths 02-05-2009
20090000949Method And Apparatus Of Concentration And Purification Of Nucleic Acid - In a method for concentration and purification method of nucleic acids using electrophoresis, cationic surfactant is added to a sample containing nucleic acids so as to adjust electric charge of impurities in the sample, and then the sample is placed in an electric field for electrophoresis so as to concentrate and purify the nucleic acids. The cationic surfactant (01-01-2009

Patent applications by ARKRAY, INC.