ARES TRADING S.A. Patent applications |
Patent application number | Title | Published |
20150150847 | USE OF N-ACETYL-5-METHOXYTRYPTAMINE OR ANALOGUES THEREOF, FOR PROMOTING THE MECHANISM OF IMPLANTATION OF THE EMBRYO AND RELATED COMPOSITIONS AND CULTURE MEDIA - The present invention refers to the use of N-acetyl-5-methoxytryptamine (melatonin) and/or an analogue thereof, for use in the medical or veterinary field in the assisted reproduction for promoting the mechanism of implantation of the embryo, and in particular for the prevention of implantation failure into the uterus, by topical administration of an effective amount in a mammalian subject female in need of such treatment, and related compositions, culture media and medical devices. | 06-04-2015 |
20150141396 | PYRIMIDINE PYRAZOLYL DERIVATIVES - The present invention provides compounds of Formula (I) for the treatment of cancer, rheumatoid arthritis and other diseases. | 05-21-2015 |
20150133507 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS - The invention relates to pharmaceutical compositions comprising PPAR agonists and Nrf2 activators and methods of using combinations of PPAR agonists and Nrf2 activators for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis. | 05-14-2015 |
20150111882 | SPIRO TETRAHYDRO - BENZOTHIOPHEN DERIVATIVES USEFUL FOR THE TREATMENT NEURODEGENERATIVE DISEASES - The present invention provide compounds of Formula (I) used as BACE inhibitors for the treatment of neurodegenerative diseases. | 04-23-2015 |
20150098950 | LIQUID FORMULATIONS OF TUMOR NECROSIS FACTOR-BINDING PROTEINS - The invention relates to a stable, pharmaceutically acceptable, aqueous formulation of TNF-binding protein, comprising a TNF-binding protein, a buffer and an isotonicity agent. | 04-09-2015 |
20140328869 | METHODS FOR IMPROVING THE DESIGN, BIOAVAILABILITY, AND EFFICACY OF RANDOM SEQUENCE POLYMER COMPOSITIONS VIA SERUM PROTEIN-BASED DETECTION OF RANDOM SEQUENCE POLYMER COMPOSITIONS - There exist in the art methods of detecting simple peptides. However, methods to determine the effective plasma concentration of mixtures of peptides as a group, rather than for individual peptides with a defined amino acid sequence, are complicated by the heterogeneity of the peptides to be detected. This application provides improved methods of detecting and assessing random sequence polymer (RSP) compositions, methods for the detection and quantitation of RSP compositions, means to determine and enrich a subset of peptides in an RSP composition based on the subset's interactions with certain capture polypeptides, and methods for administering RSP compositions to a subject in need thereof, wherein the dosage regimen and quantity may be determined or evaluated based on the above-mentioned methods for detection and quantitation. | 11-06-2014 |
20140249089 | METHODS OF TREATING DISEASE WITH RANDOM COPOLYMERS - The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein. | 09-04-2014 |
20140121162 | FREEZE-DRIED FORMULATIONS OF FGF-18 - The invention relates to the field of pharmaceutical formulations. More particularly it is directed to freeze-dried formulations of Fibroblast Growth Factor 18 (FGF-18) compound and to methods of producing such formulations. The freeze-dried formulations according to the invention are stable upon storage for an appropriate period of time. They can be used, after reconstitution, for the treatment of cartilage disorders such as osteoarthritis or cartilage injury. | 05-01-2014 |
20140105858 | IFN-BETA COMPOSITIONS, PREPARATION METHODS AND USES THEREOF - The present invention pertains to interferon-beta (IFN-beta) compositions comprising interferon-beta and a grafted poly(glutamic acid) polymer having an average molecular weight between 26,000 and 40,000 g/mol, grafted with alpha-tocopherol substituents, the average molar grafting ratio being 4.5-5.5 moles %, the weight/weight ratio between said grafted poly(glutamic acid) polymer and IFN-beta being between 24 and 125. The present invention also pertains to the preparation methods of such compositions and their application to obtain therapeutic compositions in dosage unit form delivering IFN-beta over an extended period of time. | 04-17-2014 |
20140088012 | GENOMIC MARKERS FOR PREDICTION OF LONG-TERM RESPONSE TO 2 YEARS OF GROWTH HORMONE (GH) THERAPY - The present invention relates to the use of genetic markers to identify the response to growth hormone treatment in Growth Hormone Deficiency (GHD) or Turner Syndrome (TS) patients as well as a method of treating GHD or TS patients and kits for genotyping. | 03-27-2014 |
20130172391 | PHARMACEUTICAL COMPOSITIONS - The invention relates to pharmaceutical compositions comprising PPAR agonists and Nrf2 activators and methods of using combinations of PPAR agonists and Nrf2 activators for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis. | 07-04-2013 |
20130158077 | PHARMACEUTICAL COMPOSITIONS - The invention relates to pharmaceutical compositions comprising PPAR agonists and Nrf2 activators and methods of using combinations of PPAR agonists and Nrf2 activators for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis. | 06-20-2013 |
20120282296 | METHODS FOR IMPROVING THE DESIGN, BIOAVAILABILITY, AND EFFICACY OF DIRECTED SEQUENCE POLYMER COMPOSITIONS VIA SERUM PROTEIN-BASED DETECTION OF DIRECTED SEQUENCE POLYMER COMPOSITIONS - There exist in the art methods of detecting simple peptides. However, methods to determine the effective plasma concentration of directed sequence polymers (DSPs), are complicated because DSPs are complex mixtures of peptides, as opposed to individual peptides with a defined amino acid sequence. This application provides improved methods of detecting and assessing DSP compositions, methods for the detection and quantitation of DSP compositions, means to determine and enrich a subset of peptides in a DSP composition based on the subset's interactions with certain capture polypeptides, and methods for administering DSP compositions to a subject in need thereof, wherein the dosage regimen and quantity may be determined or evaluated based on the above-mentioned methods for detection and quantitation. | 11-08-2012 |
20120276135 | METHODS FOR IMPROVING THE DESIGN, BIOAVAILABILITY, AND EFFICACY OF RANDOM SEQUENCE POLYMER COMPOSITIONS VIA SERUM PROTEIN-BASED DETECTION OF RANDOM SEQUENCE POLYMER COMPOSITIONS - There exist in the art methods of detecting simple peptides. However, methods to determine the effective plasma concentration of mixtures of peptides as a group, rather than for individual peptides with a defined amino acid sequence, are complicated by the heterogeneity of the peptides to be detected. This application provides improved methods of detecting and assessing random sequence polymer (RSP) compositions, methods for the detection and quantitation of RSP compositions, means to determine and enrich a subset of peptides in an RSP composition based on the subset's interactions with certain capture polypeptides, and methods for administering RSP compositions to a subject in need thereof, wherein the dosage regimen and quantity may be determined or evaluated based on the above-mentioned methods for detection and quantitation. | 11-01-2012 |
20120071818 | Injection Device With A Capacitive Proximity Sensor - An injection device for injecting medication to a patient, comprising a surface ( | 03-22-2012 |
20110305669 | PROCESS FOR THE PREPARATION OF GLYCOSYLATED INTERFERON BETA - The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern. | 12-15-2011 |
20110201998 | Hand-Held Electronically Controlled Injection Device For Injecting Liquid Medications - A medication delivery device includes a housing, a door coupled to the housing and moveable between a closed position and an open position. The door permits insertion of a medication container, containing liquid medication, into the housing in the open position. A door opening mechanism is coupled to the door. A push member is axially moveable between a retracted position and a non-retracted position and located external to the medication container. The push member enters the medication container and pushes the liquid medication out of the medication container. A lock mechanism is coupled to the door opening mechanism and prevents opening of the door when the push member is in the non-retracted position inside the medication container, wherein the lock mechanism automatically unlocks the door opening mechanism when the push member is in the retracted position. | 08-18-2011 |
20110097306 | ORAL FORMULATIONS OF CLADRIBINE - Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral administration of cladribine. | 04-28-2011 |
20110015145 | CLADRIBINE FORMULATIONS FOR IMPROVED ORAL AND TRANSMUCOSAL DELIVERY - Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral and buccal administration of cladribine. | 01-20-2011 |
20100261887 | TACI-IMMUNOGLOBULIN FUSION PROTEINS FOR TREATMENT OF RELAPSING MULTIPLE SCLEROSIS - The invention relates to TACI-Immunoglobulin fusion proteins for the treatment of relapsing multiple sclerosis. | 10-14-2010 |
20100227819 | Serum-Free Cell Culture Medium for Mammalian Cells - The invention relates to a process for the manufacturing of a protein in mammalian cells cultured in a serum-free medium. | 09-09-2010 |
20100196349 | REELER DOMAIN CONTAINING PROTEIN - This invention relates to protein INSP 171, herein identified as containing a Reeler domain, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease. | 08-05-2010 |
20100166703 | USE OF IL-6/IL-6 CHIMERA IN HUNTINGTON'S DISEASE - The invention relates to the use of an IL-6R/IL-6 chimera, a mutein, isoform, fused protein, functional derivative, active fraction or circularly permutated derivative or a salt thereof, for the manufacture of a medicament for the treatment and/or prevention of Huntington's disease. | 07-01-2010 |
20100160857 | Hand-Held Electronically Controlled Injection Device For Injecting Liquid Medications - A medication delivery device includes a housing, a door coupled to the housing and moveable between a closed position and an open position. The door permits insertion of a medication container, containing liquid medication, into the housing in the open position. A door opening mechanism is coupled to the door. A push member is axially moveable between a retracted position and a non-retracted position and located external to the medication container. The push member enters the medication container and pushes the liquid medication out of the medication container. A lock mechanism is coupled to the door opening mechanism and prevents opening of the door when the push member is in the non-retracted position inside the medication container, wherein the lock mechanism automatically unlocks the door opening mechanism when the push member is in the retracted position. | 06-24-2010 |
20100137195 | Production of Recombinant IL-18 Binding Protein - The invention relates to a process for the production of IL-18 binding protein (IL-18BP), and to a composition comprising IL-18BP characterized by a specific glycosylation pattern. | 06-03-2010 |
20100048467 | Cystine-Knot Fold Cytokine - This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease. | 02-25-2010 |
20100016223 | TREATMENT OF CARTILAGE DISORDERS WITH FGF-18 - This invention concerns the treatment of cartilage disorder and osteoarthritis in particular. More specifically, it relates to the use of FGF-18 in treatment regimens and for the manufacture of a medicament for the treatment of patients having a cartilage disorder such as osteoarthritis, such as for example knee osteoarthritis or secondary hip osteoarthritis. Specifically provided is a preferred treatment scheme comprising once weekly administration of an FGF-18 compound per treatment cycle. | 01-21-2010 |
20090324711 | Oral Pharmaceutical Composition of Anilinopyrimidine, Preparation and Use Thereof - An oral pharmaceutical composition comprising a capsule dosage form containing a liquid fill composition including an anilinopyrimidine derivative of Formula (I) and a pharmaceutically acceptable excipient selected from the group consisting of polyethylene glycol, a glyceryl ester of capric acid or a mixture thereof. The liquid fill composition is formulated in a hard gelatin capsules and can be used for the preparation of a medicament for the treatment of cancer in particular AML. | 12-31-2009 |
20090312713 | METHOD FOR MARKING PHARMACEUTICAL ARTICLES - A method for marking pharmaceutical articles is characterized by comprising marking the pharmaceutical articles with an ink that is invisible under normal light conditions and that is visible under specific light conditions, such as under UV light. | 12-17-2009 |
20090311732 | ANALYTICAL METHOD FOR ANALYZING C-TERMINUS TRUNCATION - This invention relates to analytical methods for quantification of truncation at the C-terminus of an Fc-containing protein. | 12-17-2009 |
20090286855 | INTERLEUKIN-18 MUTANTS, THEIR PRODUCTION AND USE - The invention provides mutants of IL-18 with lower affinity to IL-18BP than the wild type IL-18 molecule. | 11-19-2009 |
20090216182 | INJECTION DEVICE WITH A CAPACITIVE PROXIMITY SENSOR - An injection device for injecting medication to a patient, comprising a surface ( | 08-27-2009 |
20090215672 | Cys-Rich, Cell Surface Glycoproteins - This invention relates to novel proteins, termed INSP206 and INSP208 herein identified as Cys-rich, cell surface glycoproteins, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease. | 08-27-2009 |
20090214548 | TGR3-Like Protein Receptor - There are provided proteins containing a domain corresponding to the C-terminal half of a ZP domain similar to that identified in TGF-beta Receptor III and the use of the proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of diseases. In particular, the present invention relates to the use of the disclosed proteins for modulating the activity of proteins belonging to the TGF-beta superfamily. | 08-27-2009 |
20090209454 | METHOD FOR PURIFYING FSH OR A FSH MUTANT - The invention relates to a method for purifying a glycoprotein, preferably FSH or a FSH mutant comprising the steps of subjecting a liquid containing said FSH or a FSH mutant to: (1) a dye affinity chromatography; (2) a weak anion exchange chromatography; (3) a hydrophobic interaction chromatography; and (4) a strong anion exchange chromatography; which may be carried out in any order. | 08-20-2009 |
20090196726 | Device for Overturning Containers - The invention relates to a device ( | 08-06-2009 |
20090136450 | THERAPY FOR NEUROLOGICAL DISEASES - The present invention relates to compositions and methods for treating neurological diseases in a subject. More specifically, the invention relates to combination therapies for treating such diseases, using a c-kit inhibitor and a neuroactive compound. The invention may be used against a variety of demyelinating diseases, including multiple sclerosis, in any mammalian subject, particularly human subjects, and at various stages of disease progression. | 05-28-2009 |
20090124006 | Serum-Free Culture Medium for the Production of Recombinant Gonadotropins - The present invention is in the field of the manufacture of recombinant proteins. More specifically, it relates to the use of a serum-free culture medium comprising an antioxidant for the production of recombinant dimeric gonadotropins. The antioxidant may be selected from the group consisting of L-glutathione, 2-mercaptoethanol, L-methionine and a combination of ascorbic acid and of (+)-alpha-tocoplierol. | 05-14-2009 |
20090104197 | vWFA and/or ANT_IG Domain Containing Proteins - This invention relates to novel proteins (herein termed INSP141, INSP142, INSP143, and INSP144), herein identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease. | 04-23-2009 |
20090074710 | METHOD OF TREATMENT USING A CYTOKINE ABLE TO BIND IL-18BP TO INHIBIT THE ACTIVITY OF A SECOND CYTOKINE - The present invention relates to the use of a cytokine-1, preferably from the IL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein, functional derivative or fragment thereof capable of binding to IL-18BP or a mutein, fused protein, functional derivative or fragment thereof and capable of inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for the treatment or prevention of a disease which is caused or aggravated by inducing said receptor of cytokine-2. | 03-19-2009 |
20090054627 | PROCESS FOR THE PURIFICATION OF IL-18 BINDING PROTEIN - The invention relates to a process for the purification of IL-18 binding protein (IL-18BP) from a fluid using aqueous two-phase partitioning. | 02-26-2009 |
20080264794 | Dielectrophoretic Process for Retaining Polarizable Target-Particles and Device for Performing that Process - A process and a device for retaining polarizable target-particles from a fluid suspension of polarizable target-particles comprising the steps of pumping that suspension into a vertical or inclined channel and applying an alternating electric field inducing a negative dielectrophoretic force on the target-particles, the force being sufficient to push them a distance of at least or about 25 m from the surface of an electrode-bearing wall, thereby creating an upward-moving clarified fluid zone in the vicinity of that wall and a downward-moving target-particle containing fluid zone at a distance from that wall. | 10-30-2008 |
20080260690 | Interferon in Influenza - The use of an interferon (IFN) for the manufacture of a medicament for treatment and/or prevention of influenza, preferably avian influenza, is described in the present invention. | 10-23-2008 |
20080254451 | Compositions and Methods for Treating Schizophrenia and Related Disorders - The present invention relates, generally, to methods and compositions for detecting or treating mental disorders, such as schizophrenia. The present invention more particularly discloses the identification of human genes which can be used for the diagnosis, prevention and treatment of schizophrenia and related disorders, as well as for the screening of therapeutically active drugs. The invention further discloses specific polymorphisms or alleles of the CNTFR gene that are related to schizophrenia, as well as diagnostic tools and kits based on these markers. The invention can be used in the diagnosis of or predisposition to, detection, prevention and/or treatment of schizophrenia and related disorders. | 10-16-2008 |
20080254035 | Lipocalin Protein - The invention is based on the discovery that the human protein referred to herein as INSP181 protein is a lipocalin. | 10-16-2008 |
20080226640 | C1q Related Protein - This invention relates to a novel protein, termed INSP162, herein identified as a secreted protein containing c1q and collagen domains and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease. | 09-18-2008 |
20080219952 | Process For the Preparation of Glycosylated Interferon Beta - The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern. | 09-11-2008 |
20080213286 | Mam Domain Containing Protein - This invention relates to a novel protein, termed INSP152, herein identified as a secreted protein, in particular, as a MAM domain containing protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment. | 09-04-2008 |
20080200658 | Process For The Purification Of Il-18 Binding Protein - The invention relates to a process for the production of purified IL-18 binding protein (IL-18BP) from a fluid comprising affinity chromatography. | 08-21-2008 |