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Apeiron Biologics Forschungs- Und Entwicklungsgese llschaft M.B.H.

Apeiron Biologics Forschungs- Und Entwicklungsgese llschaft M.B.H. Patent applications
Patent application numberTitlePublished
20100261214Method for Determining ACE2 Activity - The present invention relates to a method of determining ACE2 activity, comprising the following steps: providing ACE2-binding units immobilized on a solid carrier and specific for a part of ACE2 which is not involved in the catalytic activity of ACE2; contacting the immobilized ACE2-binding units with a sample which potentially includes the ACE2, wherein the ACE2 is bound by the ACE2-binding unit; removing the non-binding portions of the sample from the ACE2 bound to the ACE2-binding units; adding a substrate of the ACE2 which is reacted by the ACE2 activity, with the reaction providing a signal; and measuring the change in the signal during a specific period of time, wherein the change can be correlated with the ACE2 activity.10-14-2010