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AMSTERDAM MOLECULAR THERAPEUTICS (AMT) IP B.V.

AMSTERDAM MOLECULAR THERAPEUTICS (AMT) IP B.V. Patent applications
Patent application numberTitlePublished
20110081332TREATMENT OF NON-ALCOHOLIC STEATOTIC HEPATITIS (NASH) - The present invention relates to a method for treating non-alcoholic steatotic hepatitis (NASH) in a subject by administering an effective amount of a lipoprotein lipase (LPL) therapeutic to the subject. The LPL therapeutic is advantageously a S447X protein or a derivative or variant thereof, or a nucleic acid encoding such a protein. The LPL therapeutic may be used in a gene therapy vector.04-07-2011
20100261254BACULOVIRAL VECTORS COMPRISING REPEATED CODING SEQUENCES WITH DIFFERENTIAL CODON BIASES - The present invention relates to production of proteins in insect cells whereby repeated coding sequences are used in baculoviral vectors. In particular the invention relates to the production of parvoviral vectors that may be used in gene therapy and to improvements in expression of the viral rep proteins that increase the productivity of parvoviral vectors.10-14-2010