| Amorepacific Corporation Patent applications |
| Patent application number | Title | Published |
|---|
| 20120129803 | COMPOSITION CONTAINING CHITOOLIGOSACCHARIDE FOR RECOVERING FROM FATIGUE - Disclosed is an anti-fatigue composition containing chitooligosaccharide as an active ingredient. The composition exhibits a fatigue recovery effect, and thus can be widely used in the health food or medical field. | 05-24-2012 |
| 20120107427 | COMPOSITION FOR PROMOTING ADIPOCYTE DIFFERENTIATION CONTAINING AN EXTRACT OF REHMANNIA GLUTINOSA, LICORICE, COICIS SEMEN, HORDEI FRUCTUS, CHAENOMELIS FRUCTUS, ACANTHOPANACIS CORTEX OR PUERARIAE RADIX - Disclosed is a composition containing an active ingredient comprising one or more extracts selected from the group consisting of | 05-03-2012 |
| 20120095208 | POSITIVE AND NEGATIVE EXTRACTION DEVICE AND EXTRACTION METHOD - Provided is a pressure-cycling type of extraction device comprising: an extraction unit for accommodating and extracting an extraction target substance; a compression unit for increasing the pressure inside the extraction unit; and a decompression unit for decreasing the pressure inside the extraction unit; wherein the pressure inside the extraction unit is increased and decreased by alternately operating the compression unit and the decompression unit, and the extraction unit comprises a bubbling nozzle for supplying bubbles into the extraction target substance. Further provided is a pressure-cycling type of extraction method in which a compression process and a decompression process are carried out alternately, and compositions produced by the method. The extraction device and method allow low temperature extraction, permit outstanding extraction efficiency and can prevent colour changes, olfactory changes and thermal denaturation of the extraction target substance. | 04-19-2012 |
| 20120022151 | METHOD FOR PREVENTING DAMAGE TO NUCLEAR MEMBRANE OF SKIN CELL BY ADMINISTERING AMENTOFLAVONE - Provided are a method for preventing damage to the nuclear membrane of skin cell including administering an effective amount of amentoflavone to a subject and a method for anti-aging including administering an effective amount of amentoflavone to a subject. By controlling the expression of defective lamin A induced by UV radiation or controlling the expression of phosphorylated H2A histone family, member X (H2AX) induced by UV radiation, the disclosed method prevents nuclear membrane damage and thus prevents skin cell damage. Accordingly, a composition containing amentoflavone as an active ingredient may be used as a cosmetic composition or a pharmaceutical composition. | 01-26-2012 |
| 20120015058 | PERFUME AND COSMETIC COMPOSITION WITH ANTI-STRESS AND RELAXING EFFECT - Disclosed is a perfume composition including grapefruit oil and bergamot oil and further including one or more selected from a group consisting of pine oil, lemon oil, cypress oil, rose oil and armoise oil. The perfume composition is useful in the field of beauty care, cosmetics, or the like. | 01-19-2012 |
| 20120010226 | Composition for skin external application containing gallocatechin gallate for moisturizing effect on the skin - The present invention relates to a composition for external skin application having a skin-moisturizing effect, which comprises gallocatechin gallate as an active ingredient. More particularly, the composition for external skin application comprises gallocatechin gallate as an active ingredient to activate peroxisome proliferator activated receptor isoform alpha (PPAR-α), to stimulate expression of filaggrin and involucrin that are skin-moisturizing factors, and thus to provide excellent anti-drying and skin-moisturizing effects. More particularly, the composition for external skin application may further comprise theobromine and quercetin in addition to gallocatechin gallate to maximize such effects. | 01-12-2012 |
| 20110274635 | WHITENING COMPOSITION FOR EXTERNAL SKIN APPLICATION CONTAINING OLDENLANDIA DIFFUSA WILLD, RHEUM UNDULATUM, AND BROUSSONETIA KAZINOKI EXTRACT - Disclosed is a whitening composition for external skin application. Containing one or more of | 11-10-2011 |
| 20110268824 | COMPOSITION FOR PREVENTING OR TREATING ARTHEROSCLEROSIS - A composition according to the present invention is a composition containing extract of | 11-03-2011 |
| 20110250315 | METHOD FOR PREPARING FERMENTED TEA USING BACILLUS SP. STRAINS (As Amended) - Disclosed is a method for manufacturing fermented tea having superior flavor using | 10-13-2011 |
| 20110230570 | MASK PACK COMPRISING COSMETIC COTTON-LIKE MATERIAL PREPARED FROM PAPER MULBERRY - The present invention relates to a cosmetic cotton-like material having excellent air permeability that is prepared from the paper mulberry by removing fiber-binding substances such as pectin and lignin from the paper mulberry fiber, a preparation method thereof and a mask pack comprising the cotton-like material. | 09-22-2011 |
| 20110224166 | COMPOSITION FOR ACTIVATING MITOCHONDRIA (As Amended) - The present invention relates to a composition for activating mitochondria which contains a chitooligosaccharide as an active constituent. The chitooligosaccharide can increase the activity of mitochondrial enzymes and increase the amount of mitochondrial DNA, and thus it can be suitably used as an active constituent in the composition for activating mitochondria. | 09-15-2011 |
| 20110217371 | CONTROLLED-RELEASE MICROPARTICLES AND METHOD OF PREPARING SAME - Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparticle not only allows effective dual release control of a drug but can also exhibit outstanding dissolution characteristics even when a small amount of coating substance is used. | 09-08-2011 |
| 20110212455 | METHOD OF SCREENING MATERIAL FOR IMPROVING SKIN FUNCTIONS - A method of screening a material for improving skin functions includes: (a) treating a skin cell with a candidate material; (b) detecting a change in a relative expression level of membrane-associated protein 17 (MAP17) gene; and (c) selecting a candidate material inducing the change in the expression level of the gene as a material for improving skin functions. | 09-01-2011 |
| 20110212169 | METHOD FOR PRODUCING POWDER CONTAINING NANOPARTICULATED SPARINGLY SOLUBLE DRUG, POWDER PRODUCED THEREBY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME (As Amended) - Disclosed are a method for preparing a powder containing a nanoparticulated sparingly soluble drug, a powder prepared thereby, and a pharmaceutical composition containing the same. The disclosed method includes: providing a uniformly dispersed solution of a sparingly soluble drug which is formed into nanoparticles in the presence of a surface stabilizer; mixing the uniformly dispersed solution with a water-soluble dispersant solution; and drying the mixed solution to obtain the powder. | 09-01-2011 |
| 20110160137 | COMPOSITION CONTAINING COLLAGEN PEPTIDE FOR IMPROVING SKIN CARE - The present invention relates to an oral composition for improving the beauty of the skin, which exhibits the effects of reducing skin wrinkles and inhibiting wrinkle formation. The composition contains a collagen peptide and at least one selected from the group consisting of elastin protein, hyaluronic acid and vitamin C. Particularly, the composition contains the collagen peptide, the elastin protein, hyaluronic acid and vitamin C at the optimum ratio, and when it is taken into the human body, it has no side effect, maximizes the biosynthesis of collagen in the skin dermal layer, shows excellent in vivo retention rate, and exhibits the effects of inhibiting skin wrinkle formation, maintaining or improving skin elasticity and moisturizing the skin. Thus, the composition will be useful as a health functional food for improving the beauty of the skin and preventing skin aging. | 06-30-2011 |
| 20110152318 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on. | 06-23-2011 |
| 20110135773 | COMPOSITION FOR EXTERNAL SKIN APPLICATION CONTAINING PINE KNOT EXTRACT AND METHOD FOR PREPARATION OF THE SAME - Disclosed is a composition for external skin application for preventing skin aging comprising pine knot extract as an effective ingredient. The composition prevents and improves wrinkles through of skin cell proliferation and collagen biosynthesis, and may be widely applied in the field of skin beauty care and cosmetics. | 06-09-2011 |
| 20110124719 | COMPOSITION FOR PROMOTING PRODUCTION OF HYALURONIC ACID CONTAINING KAEMPFEROL AND QUERCETIN - Disclosed is a composition for promoting a production of hyaluronic acid containing at least one of kaempferol and quercetin. Kaempferol and quercetin of the invention increase an expression of a hyaluronic acid synthase (HAS) gene existing in a skin cell line of human epidermis, thereby promoting a production of hyaluronic acid in the human cell. Accordingly, the composition containing at least one of kaempferol and quercetin according to the invention can be usefully used as a cosmetic composition for increasing skin elasticity and preventing skin dryness or aging, or a pharmaceutical composition for treating or preventing a degenerative arthritis. | 05-26-2011 |
| 20110123583 | MULTI-LAYERED LAMELLAR GRANULE AND SKIN EXTERNAL APPLICATION COMPOSITION CONTAINING SAME - Provided are: a multi-layered lamellar granule comprising a nucleating agent, a ceramide-containing artificial stratum corneum lipid lamellar layer which encases the nucleating agent and a polymer layer disposed on the artificial stratum corneum lipid lamellar layer; and an external skin application composition comprising the same. The external skin application composition shows improved moisturizing and barrier repair capabilities when applied to the skin, which can be advantageously used in cosmetics and pharmaceuticals. | 05-26-2011 |
| 20110118638 | SKIN MASSAGER - Disclosed is a skin massage device, the proposed idea capable of a skin massage device of scrubbing a skin applied with a massage cream, then giving physical stimulus on the skin at a massage thus helping the relaxation of muscles and activating matabolism to serve an elastic, healty skin, characterized in that an operation device | 05-19-2011 |
| 20110118222 | PSEUDOLIPID COMPLEX MIXTURE AND A SKIN EXTERNAL APPLICATION COMPOSITION CONTAINING SAME - Provided is a pseudolipid complex mixture comprising a pseudoceramide and a stearic acid and an external skin application composition comprising the same. The complex mixture has improved phase stability and a structure similar to that of the stratum corneum which can retain water and other beneficial materials, and accordingly the composition comprising the same can be used as an external skin application composition having improved moisturization and barrier repair capabilities. | 05-19-2011 |
| 20110117220 | PREPARATION METHOD OF PLANT EXTRACT USING HIGH PRESSURE-ENZYMATIC DECOMPOSITION TECHNIQUE AND THE COSMETIC COMPOSITION CONTAINING THE EXTRACT - The present invention relates to a method of preparing a plant extract using a high-pressure enzymatic decomposition technique (HPED technique) and to a cosmetic composition containing the prepared plant extract as an active ingredient. The plant extract prepared using the high-pressure enzymatic decomposition technique developed according to the present invention contains various kinds and large amounts of effective components compared to extracts prepared using other extraction techniques, such that the effects of the effective components can be maximized. | 05-19-2011 |
| 20110015230 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - This present disclosure relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. | 01-20-2011 |
| 20100297270 | COMPOSITION FOR TREATMENT OF ISCHEMIC HEART DISEASE, FACILITATION OF BLOOD CIRCULATION AND ANGIOGENESIS, IMPROVING SKIN BEAUTY, IMPROVING MALE SEXUAL FUNCTION CONTAINING GINSENG BERRY EXTRACT - A composition containing ginseng berry extract as active ingredient is for facilitation of blood circulation, for prevention of vascular aging, for treatment of vascular inflammation, for facilitation of angiogenesis, for treatment of ischemic heart disease, for improvement and treatment of local blood circulation insufficiency, for improvement of skin beauty and for improvement of male sexual function. More particularly, the compositions containing ginseng berry extract as active ingredient facilitate nitric oxide (NO) generation in endothelial cells, improve viability of endothelial cells, and facilitate angiogenesis through increased mobility of endothelial cells and vascular tube formation; provide antioxidative effect, facilitate biosynthesis of collagen, provide skin aging inhibiting and wrinkle improving effects through inhibition of MMP-1, provide skin whitening effect through inhibition of melanin synthesis, and provide skin moisturizing effect; and improve male sexual function through relaxation of the corpus cavernosum and enhancement of penial erection, and, as used in combination with l-arginine, which is a substrate of nitric oxide synthase, provide synergically enhanced NO generation. | 11-25-2010 |
| 20100254969 | Cosmetic Composition For Exfoliating Skin Keratin - The present invention relates to a cosmetic composition containing enzymes, and more particularly to a cosmetic composition, which contains, as active ingredients, 1) papain, and 2) at least one selected from the group consisting of theanine and N-acetyl glucosamine, and thus functions to control the skin turnover cycle and promote the exfoliation of skin keratin. | 10-07-2010 |
| 20100200013 | DEFORMABLE MASCARA BRUSH - A mascara brush is provided. The mascara brush includes a brush stick which is provided in a cap; a brush which is provided at the end of the brush stick; and an elevating bar which is connected to the brush stick in the manner of screw. The brush gets straightened to make eyelash voluminous when the elevating bar is elevated down and the brush gets curved to make eyelash curled when the elevating bar is elevated up. | 08-12-2010 |
| 20100136119 | CONTROLLED-RELEASE PREPARATION CONTAINING CILOSTAZOL AND PROCESS FOR THE PREPARATION THEREOF - A controlled release preparation which comprises particles containing cilostazol or its pharmaceutically acceptable salt dispersed in a solubilizing agent and an erodible material encasing said particles which is capable of forming a hydrogel, can maintain a constant level of cilostazol in the blood through its slow release during its prolonged residence time in the stomach and intestines, thereby minimizing adverse effects caused by rapid release of the drug or solubilizing agent. | 06-03-2010 |
| 20100120711 | AMPK POTENTIATOR CONTAINING CHITO-OLIGOSACCHARIDE - Disclosed herein is a composition for promoting AMPK activity, which comprises a chito-oligosaccharide as an active ingredient. The present composition affects the enzymes related to AMPK and lipid metabolism, and thus helps recovery from the condition lacking energy by various functions of controlling metabolism. Therefore, the present composition can enhance energy metabolism, thus making the composition effective for improving exercise capacity and reducing fatigue. The present composition can be used in the preparation of food or medicinal product as an endurance builder or for the prevention and improvement of fatigue. | 05-13-2010 |
| 20100120042 | METHOD OF SCREENING MATERIAL FOR IMPROVING SKIN FUNCTIONS - A method of screening a material for improving skin functions includes: (a) treating a skin cell with a candidate material; (b) detecting a change in a relative expression level of membrane-associated protein 17 (MAP17) gene; and (c) selecting a candidate material inducing the change in the expression level of the gene as a material for improving skin functions. That is to say, a material for improving skin functions is screened using MAP17 gene as a marker, on the basis of the change in the expression level of the MAP17 gene. A material for improving skin functions, which is useful in improving skin barrier function, promoting skin moisturization, preventing skin aging, or ameliorating skin troubles, may be effectively screened. | 05-13-2010 |
| 20100119628 | Anti-aging cosmetic composition - The present invention relates to an anti-aging cosmetic composition, and more particularly, the present invention relates to an anti-aging cosmetic composition containing | 05-13-2010 |
| 20100113372 | Method For Preparing Kaempferol-3-0-Rutinoside and Composition of Skin External Application Comprising Thereof - Disclosed is a method for the preparation of kaempferol-3-O-rutinoside and a composition of a skin external application comprising kaempferol-3-O-rutinoside as an active ingredient. The method for isolating kaempferol-3-O-rutinoside through hydrolysis uses an enzyme or microbe that removes the sugar selectively from kaempferol-3-O-rutinoside glycosides in a plant extract. Disclosed also is a composition of a skin external application comprising kaempferol-3-O-rutinoside that prevents skin wrinkle. | 05-06-2010 |
| 20100104522 | COMPOSTION FOR SKIN EXTERNAL USE CONTAINING OMEGA-3 FATTY ACID - Stable preparations containing omega-3 fatty acid as an effective ingredient are disclosed. Further, uses of omega-3 fatty acid in preventing or alleviating skin aging, moisturizing skin, improving skin roughness, restoring or strengthening skin barrier function, improving skin elasticity, recovering or preventing skin damage induced by UV are disclosed. | 04-29-2010 |
| 20100098759 | CONTROLLED-RELEASE PREPARATION CONTAINING CILOSTAZOL AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to a controlled-release formulation comprising cilostazol and a method for preparing said formulation. The inventive controlled-release formulation comprising cilostazol or a pharmaceutically acceptable salt thereof, a solubilizing agent, a swelling agent, a swell-controlling agent and a gas generating material has advantages in that it maintains a constant cilostazol level in the blood through a slow release while it resides in the stomach and intestines over a long period of time, thereby increasing the absorption of cilostazol in the small intestine, the major absorption site of cilostazol, as well as minimizing adverse effects caused by rapid release and making it easy for a patient to take the drug. | 04-22-2010 |
| 20100069483 | DUAL INHIBITION OF CYCLOOXYGENASE-2 AND CARBONIC ANHYDRASE - Compounds of Formula I potently inhibit both cyclooxygenase-2 and carbonic anhydrases. Inhibition of carbonic anhydrases by a cyclooxygenase-2 inhibitor may affect significantly the safety and efficacy profiles of such a dual inhibitor in the treatment of cyclooxygenase-2 mediated disorders, compared to a cyclooxygenase-2 inhibitor without carbonic anhydrase inhibitory activity. | 03-18-2010 |
| 20100068310 | EXTERNAL COMPOSITION FOR SKIN CONTAINING SCROPHULARIA BUERGERIANA MIQ. EXTRACT AND THE USE THEREOF FOR THE SKIN MOISTURIZING COSMETICS - Disclosed herein is a skin external composition for alleviating dry skin symptoms, which contains an extract of | 03-18-2010 |
| 20100062492 | Method For Preparing Icariside II, Cosmetic Composition Containing The Same and the Use Thereof For Skin Whitening - Disclosed are a method for preparing icariside II represented by Formula 1, which inhibits the glycosylation of glycoprotein enzyme tyrosinase by inhibiting the enzymatic activity of alpha-glucosidase, which is an enzyme in the glycosylation of tyrosinase, as well as a skin whitening composition. | 03-11-2010 |
| 20100015187 | MACRO-SIZED LIPID CAPSULE EMULSION COMPOSITION AND COSMETIC COMPOSITION CONTAINING THE SAME - An emulsion composition of the invention has macro-sized (0.01 to 5 mm) lipid capsule particles and it is for a skin cosmetic composition. An emulsion composition of the invention exhibits improved stability for its particle size by adjusting a size of the particle through a combination of liquid phase oil and integument lipid or lipoid material and encapsulating the liquid phase oil with the integument lipid. The emulsion composition of the invention has unique outward appearance and use feeling due to the macro-sized particles in it, also exhibits excellent skin safety and moisture persistence by containing no surfactant and maintains an activity of an oleophilic effective ingredient which is apt to be oxidized for a long time. | 01-21-2010 |
| 20100003332 | Process For Preparing Powder Comprising Nanoparticles of Sparingly Soluble Drug - A powder comprising nanoparticles of a sparingly water-soluble drug prepared in accordance with the present invention exhibits enhanced bioavailability without generating adverse side effects caused by impurities, while the nano-particle size of the drug remains unchanged when administered. Accordingly, the powder can be useful for the development of a formulation of a sparingly water-soluble drug for oral and parenteral administration. | 01-07-2010 |
| 20090252782 | Transdermal Preparations Containing Hydrophoic Non-Steroidal Anti-Inflammatory Drugs - Disclosed is a transdermal preparation containing a hydrophobic drug. As a method of continuing the high drug permeation, it is used an unique hydrophilic polymer system in which the drug can be contained in a high concentration under no water environment, a solubility of the hydrophobic drug is decreased as the water is introduced to the patch from the skin, so that the drug is maintained at the saturation concentration even though the drug content is decreased as the drug is permeated to the skin. During the application of the transdermal preparation to the skin, it is possible to continuously permeate the high amount of drug, to maintain the sufficient adhesion during the use and to minimize the skin side effect, because the hydrophilic polymer absorbs the water from the skin. The hydrophilic polymer system can serve the function thereof through the hydrophobic adhesive layer capable of preventing the water quickly absorbed from the skin from being evaporated to the outside of the patch. | 10-08-2009 |
| 20090176810 | COMPOSITION FOR SKIN EXTERNAL APPLICATION CONTAINING GALLOCATECHIN GALLATE FOR MOISTURIZING EFFECT ON THE SKIN - The present invention relates to a composition for external skin application having a skin-moisturizing effect, which comprises gallocatechin gallate as an active ingredient. More particularly, the composition for external skin application comprises gallocatechin gallate as an active ingredient to activate peroxisome proliferator activated receptor isoform alpha (PPAR-α), to stimulate expression of filaggrin and involucrin that are skin-moisturizing factors, and thus to provide excellent anti-drying and skin-moisturizing effects. More particularly, the composition for external skin application may further comprise theobromine and quercetin in addition to gallocatechin gallate to maximize such effects. | 07-09-2009 |
| 20090131686 | Sesamol Derivatives or Their Salts, The Process for Preparing the Same, and the Skin External Composition Containing the Same - The present invention relates to a sesamol derivative or its salt, and a skin external composition containing the same. More particularly, the invention relates to a sesamol derivative or its salt, which consists of sesamol and 3-aminopropane phosphoric acid, linked with each other by a phosphoric acid diester bond, and can be degraded into sesamol and 3-aminopropane phosphoric acid by enzymes present on the skin so as to simultaneously show the physiological activities of sesamol and 3-aminopropane phosphoric acid, as well as a preparation method thereof and a skin external composition containing the same. | 05-21-2009 |
| 20090105258 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salt thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease. | 04-23-2009 |
| 20090068277 | PHARMACEUTICAL COMPOSITION COMPRISING LIPASE INHIBITOR AND LIPOPHILIC OIL ABSORBENT AND ORAL FORMULATION PREPARED THEREFROM - This invention provides a pharmaceutical composition comprising a lipase inhibitor; a lipophilic oil absorbent selected from the group consisting of hydrogenated castor oil, hydrogenated vegetable oil, glyceryl behenate, glyceryl palmitostearate and a mixture thereof; and a pharmaceutically acceptable additive, an oral formulation of a lipase inhibitor prepared there from and a method for preparing said formulation. The formulation of the present invention can minimize side effects such as oily spotting, fatty/oily stool, abdominal distension and flatus, and thus it can be advantageously used for preventing or treating obesity and hyperlipaemia. | 03-12-2009 |
| 20090062217 | Promoter For The Production Of Hyaluronic Acid Containing Ginsenoside Compound K - There are provided a promoter containing ginsenoside compound K for the production of hyaluronic acid, and more particularly, a new efficacy of 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (compound K), a chief metabolite of ginseng saponin, to increase the expression of hyaluronic acid synthase gene in human cell and thereby to promote the production of hyaluronic acid, and an anti-aging agent containing the promoter for the production of hyaluronic acid as an effective ingredient. | 03-05-2009 |
| 20090036501 | 2-Cyclopenten-1-One Oxime Derivatives Inhibiting Production of TNF-Alpha - 2-cyclopenten-1-one oxime derivatives represented by Formula (I), or pharmaceutically acceptable salts thereof inhibit the production of TNF-α or PDE4, and therefore show therapeutic effect in inflammatory or immunological disorders mediated through TNF-α or PDE4. | 02-05-2009 |
| 20080314403 | Mascara Brush - Provided is a disk-type mascara brush, used to makeup eyelash with mascara solution applied thereto, whose brush portion is formed whole at the end of a wand and in such a shape that pluralities of triangle-like elliptic disks are piled consecutively with an alternated arrangement with the angle of 120 degree. In a disk-type mascara brush where a brush portion | 12-25-2008 |
| 20080312234 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on. | 12-18-2008 |
| 20080306146 | Dosing Regimens for Cox-2 Inhibitor - The present invention relates to a potent cyclooxygenase-2 inhibitor and dosing regimens thereof to safely treat cyclooxygenase-2 mediated disorders. | 12-11-2008 |
| 20080300301 | Composition for Promoting Production of Hyaluronic Acid Containing Kaempferol and Quercetin - Disclosed is a composition for promoting a production of hyaluronic acid containing at least one of kaempferol and quercetin. Kaempferol and quercetin of the invention increase an expression of a hyaluronic acid synthase (HAS) gene existing in a skin cell line of human epidermis, thereby promoting a production of hyaluronic acid in the human cell. Accordingly, the composition containing at least one of kaempferol and quercetin according to the invention can be usefully used as a cosmetic composition for increasing skin elasticity and preventing skin dryness or aging, or a pharmaceutical composition for treating or preventing a degenerative arthritis. | 12-04-2008 |
| 20080286375 | Method for Preparing Sustained-Release Microparticles Comprising Sucrose Acetate Isobutyrate - A sustained release microparticles which is capable of releasing a protein drug continuously over a long period of time without initial burst release of the drug can be simply prepared by a method including the steps of a) dissolving a protein drug in an aqueous solution to obtain a water phase; b) dissolving sucrose acetate isobutyrate (SAIB) and a biodegradable polymer in an organic solvent to obtain an oil phase; c) adding the water phase obtained in step a) to the oil phase obtained in step b) to form a primary emulsion; and d) adding the primary emulsion to an external aqueous continuous phase to form a secondary emulsion and recovering the solid product formed in the secondary emulsion. | 11-20-2008 |
| 20080280838 | Composition Containing Ginsenoside F1 and Egcg for Preventing Skin Damage - The present invention relates to a skin-care composition containing ginsenoside F1 and EGCG. More particularly, the present invention relates to an inhibitor of UV-induced apoptosis in epidermal cells showing an excellent skin-care effect by the synergistic interaction of the said ginsenoside F1 and EGCG even at low concentrations, and to a method for inhibiting apoptosis in epidermal cells. | 11-13-2008 |
| 20080280335 | Manufacturing Method of Kaempferol - Disclosed is a kaempferol preparing method comprising isolating kaempferol from kaempferol glucosides using an acid, a base, an enzyme or a microbe producing the enzyme. More specifically, the method comprises obtaining a plant extract containing kaempferol glycosides from a plant using water or an organic solvent; and hydrolyzing the plant extract using an acid, a base, an enzyme or a microbe producing the enzyme to isolate kaempferol. The kaempferol glycosides comprise camelliaside A or camelliaside B. The plant extract is derived from a seed or leaf of green tea. When using the method of the invention, it is possible to mass-produce kaempferol, which is one of main physiological activating ingredients, from a plant, particularly a seed or leaf of green tea. | 11-13-2008 |
| 20080268035 | Cationic Polymer Nanoparticles Encapsulating An Active Ingredients, And The Cosmetic Composition Containing The Same - Disclosed herein are cationic polymer nanocapsules encapsulating an oil-soluble active ingredient, and a cosmetic composition containing the same. The cationic polymer nanocapsules have a molecular weight of 5,000-100,000, a surface potential of 5-100 mV and a particle size of 50-500 nm. Also, disclosed is a cosmetic composition containing said cationic polymer nanocapsules. | 10-30-2008 |
| 20080268004 | Stable Water-In-Oil-In-Water Multiple Emulsion System Produced By Hydrodynamic Dual Stabilization And A Method For Preparation Thereof - The present invention relates to a water-in-oil-in-water multiple emulsion system and a method for preparation thereof, characterized by hydrodynamically stabilizing the multiple emulsion system by using hydrodynamic dual stabilization (HDS) technology. The HDS technology hydrophobizes water molecules in the internal aqueous phase by using a hydrogen bonding inhibitor and by improving the aggregating force between water molecules in the internal aqueous phase by using a water molecule aggregating agent. | 10-30-2008 |
| 20080261899 | AGENT FOR CONTROLLING Bcl-2 EXPRESSION COMPRISING GINSENOSIDE F1 AS AN ACTIVE COMPONENT - The present invention relates to an agent for controlling Bcl-2 expression comprising ginsenoside F1 (20-O-β-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the following formula 1 as an active component. | 10-23-2008 |
| 20080255238 | COMPOSITION CONTAINING A THIOUREA DERIVATIVE FOR PREVENTING OR TREATING PRURITIC OR IRRITANT SKIN DISEASES - Disclosed herein is a composition for preventing or treating pruritic or irritant skin diseases which comprises, as a vanilloid receptor antagonist, a thiourea derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, together with a pharmaceutically acceptable carrier. | 10-16-2008 |
| 20080226738 | Sustained-Released Pellet Formulation of Alpha1-Receptor Antagonist and Process For the Preparation Thereof - A sustained-release pellet formulation comprising: a pellet core comprising an α1-receptor antagonist, a pellet-forming substance and a pharmaceutically acceptable excipient and a coating layer comprising an enteric coating substance and a water-insoluble polymer, which is coated on said pellet core maintains a therapeutically effective drug level in the blood for a sufficient time without an initial burst and sustains the release of the drug even in the small intestine due to the water-insoluble polymer in the coating layer | 09-18-2008 |
