| ALVERIX, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120129272 | LATERAL FLOW ASSAY SYSTEMS AND METHODS - In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements. | 05-24-2012 |
| 20110275162 | ASSAY READER OPERABLE TO SCAN A TEST STRIP - Low-cost assay test strip readers are disclosed. Such readers enable creation of profiles of analyte reactions detected on an assay test strip utilizing a simple detector fixedly mounted to a body of the reader. The detector may be a single detector, such as a photodetector, which detects an optical signal at a single point. The assay test strip is inserted and/or removed from the test strip reader and the detector detects the optical elements of the strip during such insertion and/or removal. The movement of the test strip with respect to the body enables the detector to scan a length of the test strip, such that a one-dimensional profile of the optical signals can be generated. The reader may convert the detected profile into a displayable indication of analyte concentrations for diagnostic purposes. Moving the test strip relative to an array of detectors enables creation of a two-dimensional profile. | 11-10-2011 |
| 20100177930 | METHODS FOR DETERMINING A WAVEFRONT POSITION - The present disclosure relates to methods for determining a wavefront position of a liquid on a surface of an assay test strip placing a liquid on the surface of the test strip; and acquiring one or more signals from the surface of the test strip at one or more times, comparing the one or more acquired signals to a threshold, wherein the wavefront position is a position on the surface of the test strip where a signal is greater than or less than a threshold (e.g., fixed or dynamic threshold). Such methods may be used to determine the wavefront velocity of a liquid on a surface of an assay test strip and the transit time of a liquid sample to traverse the one or more positions on the surface of the assay test strip. | 07-15-2010 |
| 20100177176 | VIDEO-FRAME DATA RECEIVER WITH LOW FRAME CAPTURE RATE - The present disclosure relates generally to a video frame data receiver that is capable of image acquisition at low frame rates. Such video frame data receivers may be used to capture images from diagnostic tests or assays in which lower frame capture rates are sufficient including, for example, lateral flow test strips. | 07-15-2010 |
| 20100176279 | METHODS AND MATERIALS FOR DETECTING LIGHT RELEASED FROM A LABELING MATERIAL - The present disclosure relates generally to methods and materials for detecting light absorbed or released from a labeling material. In particular, the present disclosure provides a detection architecture and devices employing the detection architecture for real-time subtraction of a background light from a light absorbed or released from a labeling material. Devices employing the detection architecture of the present disclosure may be used in methods for detecting a light absorbed or released from a labeling material by contacting a labeling material with a light source, wherein the fluorescent label absorbs or releases a first light; detecting the first light after the light source is enabled with a detector, wherein the detector produces a first signal from the first light; turning on a first switch at a first time for a fixed interval to receive the first signal from the first light; detecting a background noise with a detector after the light source is disabled, wherein the detector produces a second signal from the background noise; turning on a second switch at a second time for a fixed interval to receive the second signal from the second light; feeding the first signal and the second signal into a differential amplifier, wherein the differential amplifier subtracts the second signal from the first signal and produces an output signal; and measuring the output signal emitted from the differential amplifier. | 07-15-2010 |
| 20100176274 | METHODS AND MATERIALS FOR DETECTING LIGHT RELEASED FROM A LABELING MATERIAL USING SELF TRIGGERING EXCITATION. - The present disclosure relates generally to methods and materials for detecting light released from a labeling material using self triggering excitation. In particular, the present disclosure provides an architecture for a detection system that detects accumulated phase shifts in the form of a ring-oscillator frequency. The present disclosure provides devices for detection of a light released by a labeling material, the device comprising: a start-up circuit that provides power to a pulse generator block that drives an LED driver, a photodetector that detects the light released by a labeling material and provides a first signal; a variable reference that provides a second signal; a slicer for comparing the first signal to the second signal, wherein the slicer generates an output signal with a delay that triggers the pulse generator block after the start-up circuit is disabled; a frequency reference; and a frequency counter for comparing the output from the slicer to the frequency reference thereby producing a output signal. | 07-15-2010 |
| 20100175455 | METHODS AND MATERIALS FOR CALIBRATION OF A READER - The present disclosure relates generally to devices that may be used to calibrate a reader. Such devices may comprise an electrical memory chip, a calibration device comprising an optical check, and an interface that allows interaction with the reader. | 07-15-2010 |
| 20090214383 | ASSAY TEST STRIPS WITH MULTIPLE LABELS AND READING SAME - In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described. | 08-27-2009 |
