Althea Technologies, Inc.
|Althea Technologies, Inc. Patent applications|
|Patent application number||Title||Published|
|20140086988||Stabilized Protein Crystals, Formulations Containing Them and Methods of Making Them - This invention relates to methods for the stabilization, storage and delivery of biologically active macromolecules, such as proteins, peptides and nucleic acids. In particular, this invention relates to protein crystals, formulations and compositions comprising them. Provided are methods and compositions for encapsulating proteins, glycoproteins, enzymes, antibodies, hormones and peptide crystals or crystal formulations into compositions for biological delivery.||03-27-2014|
|20120282464||Spherical Protein Particles and Methods of Making and Using Them - This invention relates to SPPs, spherical nanocrystalline composite particles or crystalline SPPs of biologically active proteins or compositions, including formulations, comprising such SPPs, spherical nanocrystalline composite particles or crystalline SPPs. More particularly, methods are provided for the production of SPPs, spherical nanocrystalline composite particles or crystalline SPPs of high concentrations of biologically active proteins, and for the preparation of stabilized SPPs, spherical nanocrystalline composite particles or crystalline SPPs for use alone, or in dry or slurry compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active proteins using SPPs, spherical nanocrystalline composite particles or crystalline SPPs. The present invention further relates to methods using SPPs, spherical nanocrystalline composite particles or crystalline SPPs, or compositions or formulations comprising such SPPs, spherical nanocrystalline composite particles or crystalline SPPs, for biomedical applications, including biological delivery to humans and animals.||11-08-2012|
|20120088724||Human Growth Hormone Formulations - Formulations containing complexed human growth hormone crystals are described. Also described are needleless injection systems for crystalline proteins.||04-12-2012|
|20110171268||URICASE COMPOSITIONS AND METHODS OF USE - Compositions containing uricase are disclosed. Methods of treating a disorder associated with elevated uric acid concentrations using uricase are also described. Compositions containing uricase and catalase are also disclosed. Methods of treating a disorder associated with elevated uric acid concentrations using uricase and catalase are also described.||07-14-2011|
|20110092387||Expression profiling using microarrays - The invention provides novel compositions and methods for the analysis of gene expression (e.g., expression profiling) using microarray-based technology. In some embodiments of the invention, the novel methods use gene-specific as well as universal amplification primers during sample preparation, and the methods permit the simultaneous analysis of multiple samples on the same microarray. Furthermore, some embodiments of the invention incorporate barcode sequences into the amplified products, thereby permitting the use of generic arrays and generic labeled probes.||04-21-2011|
|20090149346||Strategies for gene expression analysis - The invention provides methods for screening compound or chemical libraries by analyzing expressed RNA samples from biological samples treated with members of a compound library in a high throughput format.||06-11-2009|
|20090148838||Methods for analysis of gene expression - This invention provides methods, compositions and kits for gene expression analysis and gene expression profiling. The methods of the invention are highly sensitive; have a wide dynamic range; are rapid and inexpensive; have a high throughput; and allow the simultaneous differential analysis of a defined set of genes. The methods, compositions and kits of the invention also provide tools for gene expression data collection and relational data analysis.||06-11-2009|
|20090110639||PREDICTING VACCINE EFFICACY - The present invention provides methods for evaluating a vaccine, combinations of tests and reaction mixtures that can be used as part of such methods, and collections of results comprising results obtained from such methods. The methods, combinations, and collections are useful for determining whether a vaccine is effective and, for example, for comparing the efficacy of different vaccines.||04-30-2009|
Patent applications by Althea Technologies, Inc.