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ALPHORA RESEARCH INC.

ALPHORA RESEARCH INC. Patent applications
Patent application numberTitlePublished
20110184192PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN - Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A:07-28-2011
20110112312PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN - Fused cyclopentane-4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A:05-12-2011
20100063330PARICALCITOL PURIFICATION - Paricalcitol, a synthetic vitamin D analog, is purified to a purity greater than 99.7% by crystallization from solution in isopropyl acetate solvent, followed by filtration and vacuum drying. Isopropyl acetate appears to be unique among commonly available and pharmaceutically acceptable solvents in its ability to precipitate paricalcitol in this high purity, essentially free of isomers thereof.03-11-2010
20100063307PARICALCITOL PURIFICATION - Paricalcitol, a synthetic vitamin D analog, is purified to a purity greater than 99.7% by crystallization from solution in isopropyl acetate solvent, followed by filtration and vacuum drying. Isopropyl acetate appears to be unique among commonly available and pharmaceutically acceptable solvents in its ability to precipitate paricalcitol in this high purity, essentially free of isomers thereof. In addition, paricalcitol of purity of at least 99.9% has been shown to have exceptional storage stability.03-11-2010
20100056808PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN - Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A:03-04-2010
20100056807PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN - Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A:03-04-2010
20080312465INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF DRONABINOL - Dronabinol, the tetrahydrocannabinol compound which comprises the active constituent of marijuana and is pharmaceutically useful as an antiemetic, is prepared by a process involving reaction of cis-menth-1-ene-3,8-diol with olivetol to form 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxyprop-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene; and cyclizing the 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxypropr-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene so formed to obtain dronabinol. A novel synthesis of cis-menth-1-ene-3,8-diol is also provided.12-18-2008

Patent applications by ALPHORA RESEARCH INC.