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Patent application numberTitlePublished
20120129709SENSOR FOR DETECTION OF NUCLEIC ACID - A sensor for detection of target nucleic acid comprising (a) a semiconductor nanostructure; and (b) a nucleic acid detection probe immobilized on the semiconductor nanostructure capable of hybridizing with the target nucleic acid, the detection probe comprising a polymer with a substantially non-ionic backbone.05-24-2012
20120129257Apparatus For Culturing Anchorage Dependent Cells - The invention relates to an apparatus (05-24-2012
20120126906Relaxation Oscillator - A relaxation oscillator and a method for offset cancellation in a relaxation oscillator. The relaxation oscillator comprises two comparator units, each comparator unit comprising a comparator element and a memory element; and a switch control generator coupled to each of the comparator units; wherein each comparator unit, in a reset state, stores an input-offset voltage on the memory element under the control of the switch control generator such that, in a comparison state, the input-offset voltage is applied to both inputs of the comparator for implementing an offset-free threshold.05-24-2012
20120122159PCR-BASED METHOD OF SYNTHESIZING A NUCLEIC ACID MOLECULE - There is provided a method of synthesizing a nucleic acid molecule and in one aspect, the method comprises assembling a full length template nucleic acid molecule by PCR in a PCR reaction mixture comprising a set of assembly oligonucleotides having a first average melting temperature and a set of outer amplification primers having a second average melting temperature that is lower than the first average melting temperature, wherein said assembling comprises subjecting the PCR reaction mixture to a first annealing temperature that is higher than the second average melting temperature and; amplifying the full length template nucleic acid molecule by PCR in the PCR reaction mixture wherein said amplifying comprises subjecting the PCR reaction mixture to a second annealing temperature that permits annealing of the outer amplification primers to the full length template nucleic acid molecule.05-17-2012
20120117018METHOD FOR THE SYSTEMATIC EVALUATION OF THE PROGNOSTIC PROPERTIES OF GENE PAIRS OF MEDICAL CONDITIONS, AND CERTAIN GENE PAIRS IDENTIFIED - A method is proposed identification of pairs of genes for which the respective gene expression values in a subject are statistically significant in relation to a medical condition, for example cancer, or more particularly breast cancer. Many pairs of genes are generated, and for each pair of genes clinical data is used to fit a statistical model to obtain the statistical significance of the ratio of the corresponding expression values. The clinical data characterizes for each of the patients the level of expressions of the genes and times until a clinical endpoint of interest.05-10-2012
20120114167REPEAT CLIP IDENTIFICATION IN VIDEO DATA - A method and System for identifying repeat clip instances in video data. The method comprises partitioning the video data into ordered video units utilising content-based keyframe sampling, wherein each video unit comprises a sequence interval between two consecutive keyframes; creating a fingerprint for each video unit; grouping at least two consecutive video units into one time-indexed video segment; and identifying the repeat clip instances based on correlation of the video segments. The method can be used for both discovering unknown repeat video clips and identifying instances of known repeat video clips automatically. The method can be used to identify short repeat video clips from less than a second long to a few minutes, such as tv station logos, program logos, tv commercials which are widely used in news video and other daily broadcasting programs.05-10-2012
20120112218Light Emitting Diode with Polarized Light Emission - An apparatus for emitting polarized light and a method for fabricating such apparatus are provided. The apparatus includes a surface emission light emitting diode (LED), a first electrode, and a sub-wavelength metal grating (SWMG). The surface emission LED includes a first contact surface and a second contact surface. The first electrode is coupled to the first contact surface. The SWMG is formed on a surface of the surface emission LED.05-10-2012
20120107413PRE-NATAL MESENCHYMAL STEM CELLS - We describe an pre-natal mesenchymal stem cell obtainable from a pre-natal tissue such as a foetal tissue, a descendent of such a mesenchymal stem cell, a cell culture or a cell line comprising either. The pre-natal mesenchymal stem cell, cell culture or cell line may comprise a cell line F1Ib, F2lb, F3lb, F1ki or F3li. We further describe a conditioned medium conditioned by such a pre-natal mesenchymal stem cell, cell culture or cell line. These may comprise cardioprotective activity, and may in particular be used to treat or prevent a range of cardiac disorders of diseases.05-03-2012
20120100545METHOD AND/OR PRIMERS FOR THE DETECTION OF MYCOBACTERIUM TUBERCULOSIS - The invention provides oligonucleotide(s) for simple, specific and/or sensitive test(s) for the presence of 04-26-2012
20120100144Biomarker and Treatment for Cancer - A correlation between expression of JMJD6 polypeptide and breast cancer metastasis exists accordingly the present invention relates a diagnostic, prognostic and therapeutic biomarker to distinguish between early and advanced/metastatic cancer particularly breast cancer, including compounds and methods to treat the same.04-26-2012
20120088938METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL - Disclosed is a method for producing an optically active alcohol including reacting a titanium compound, an aromatic magnesium compound and a carbonyl compound in the presence of an optically active biphenol compound having a predetermined structure and an ether compound having a predetermined structure.04-12-2012
20120087899Heparan Sulphate - Heparan sulphate from bone marrow stroma is disclosed together with the use of heparan sulphate from bone marrow stroma in the differentiation and/or lineage commitment of stem cells.04-12-2012
20120087418Communication Device and Method of Determining a Ranging Value in the Communication Device - A communication device and a method of determining a ranging value in the communication device are provided. The communication device, includes: a transmitter path, including: a transmitter clock generating circuit configured to generate a transmitter clock signal; a receiver path, including: a clock recovery circuit configured to recover a receiver clock signal from a received signal; a comparator circuit coupled to the clock recovery circuit and configured to compare the receiver clock signal and the transmitter clock signal to generate an output signal; a ranging determination circuit configured to determine a ranging value based on the output signal.04-12-2012
20120086802SYSTEM AND METHOD FOR MONITORING WATER QUALITY - A system and system for monitoring water quality. The system comprises a container for receiving a flow of water to be monitored, the container containing a plurality of fish and configured such that a substantially 3-dimensional group behaviour of the fish is accommodated; a first imaging device disposed above the container for obtaining top view video data of the fish; and means for identifying individual fish based on foreground object detection.04-12-2012
20120082865METHOD FOR FORMING A MAGNETIC RECORDING MEDIUM AND A MAGNETIC RECORDING MEDIUM FORMED THEREOF - A method for forming magnetic media is provided. The method of forming the magnetic media includes forming a plurality of regions of resist material on a top surface of a substrate which defines a plurality of regions of exposed substrate on the top surface of the substrate between adjacent ones of the plurality of regions of resist material. The method also includes forming magnetic material on the plurality of regions of resist material and the plurality of regions of exposed substrate and depositing material over the magnetic material, the material encapsulating a portion of the magnetic material formed on the plurality of regions of exposed substrate. A magnetic recording medium formed in accordance with the method is also provided.04-05-2012
20120077841METHODS FOR CANCER THERAPY AND STEM CELL MODULATION - The present invention relates to a method of modulating pluripotency and/or self-renewing characteristics of a stem/progenitor cell. The method comprises administering to the respective cell a compound of the general formula (I)03-29-2012
20120063973Flexible Fluid Storage and Warming Bag and a Fluid Storage and Warming System - In an embodiment, a flexible fluid storage and warming bag may be provided. The flexible fluid storage and warming bag may include two flexible main walls, each including a surrounding edge, the two flexible main walls overlapping each other and being fluid-tightly sealed together along the surrounding edges thereof, the bag including a single non-partitioned fluid chamber defined by and between the two flexible main walls and by the sealed surrounding edges; at least one fluid transfer port extending into the single non-partitioned fluid chamber and being configured to allow transfer of the fluid into and out of the bag; and an electrical heating element integrated with at least one of the two flexible main walls of the bag. A fluid storage and warming system may also be provided.03-15-2012
20120045760Single Nucleotide Polymorphism Within An Intronic P53 Binding Motif of the Prkag2 Gene - The present invention relates to single nucleotide polymorphism (SNP). In particular, it relates to a SNP within an intronic p53 binding motif of the PRKAG2. Nucleic acid molecules and methods for aiding assessment of a patient's risk of developing cancer by determining the patient's genotype for a p53 binding motif within the PRKAG2 gene are included in the present invention.02-23-2012
20120045514ANTI-CANCER MICROPARTICLE - The present invention relates to a microparticle and its use. The microparticle has a width of at least about 1 micron. The microparticle includes a biocompatible polymer, a nanoparticle, and an anti-cancer agent.02-23-2012
20120037208THIN FILM SOLAR CELL STRUCTURE - A thin film solar cell structure and method of fabricating a thin film solar cell structure. The thin film solar cell structure comprises a photoelectric conversion structure; a grating coupler for coupling incident light into the photoelectric conversion structure; and a resonator structure for providing a light trapping in the photoelectric conversion structure.02-16-2012
20120035288FORMING COPOLYMER FROM BICONTINUOUS MICROEMULSION COMPRISING MONOMERS OF DIFFERENT HYDROPHILICITY - A copolymer defines interconnected pores and comprises polymerized monomers. The monomers comprise a first monomer more hydrophilic than 2-hydroxyethyl methacrylate (HEMA), and a second monomer as hydrophilic as, or less hydrophilic than, HEMA. In a method of forming a polymer, a bicontinuous microemulsion comprising water, a surfactant, and a combination of monomers copolymerizable for forming a porous copolymer is provided. The combination of monomers comprises the first and second monomers. The monomers in the bicontinuous microemulsion are polymerized to form the porous copolymer. The first monomer may comprise N-vinylpyrrolidone (NVP) or methacrylic acid (MAA). The second monomer may comprise HEMA or methyl methacrylate (MMA).02-09-2012
20120032122METHOD FOR FORMING A CADMIUM CONTAINING NANOCRYSTAL - The present invention provides a method of forming a nanocrystal of the composition CdA, with A being S or Se. The method includes forming in a suitable solvent a solution of cadmium, or a compound thereof, in a form suitable for the generation of a nanocrystal. The solvent includes a compound selected from an ether and an amine. The method further includes bringing the solution to a temperature selected in the range from about 20° C. to about 200° C. The method also includes adding at the temperature selected in the range from about 20° C. to about 200° C. the element A in a form suitable for the generation of a nanocrystal. Thereby the forming of a nanocrystal of the composition CdA is allowed.02-09-2012
20120028352Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.02-02-2012
20120016595TRANSCRIPT MAPPING METHOD - A transcript mapping method according to an embodiment of the invention is described hereinafter and combines short tag based (SAGE and MPSS) efficiency with the accuracy of full-length cDNA (flcDNA) for comprehensive characterization of transcriptomes. This method is also referred to as Gene Identification Signature (GIS) analysis. In this method, the 5′ and 3′ ends of full-length cDNA clones are initially extracted into a ditag structure, with the ditag concatemers of the ditag being subsequently sequenced in an efficient manner, and finally mapped to the genome for defining the gene structure. As a GIS ditag represents the 5′ and 3′ ends of a transcript, it is more informative than SAGE and MPSS tags. Segment lengths between 5′ and 3′ tag pairs are obtainable including orientation, ordering and chromosome family for efficient transcript mapping and gene location identification. Furthermore, a compressed suffix array (CSA) is used for indexing the genome sequence for improve mapping speed and to reduce computational memory requirements.01-19-2012
20120013351METHOD FOR CONVERTING A SENSOR CAPACITANCE UNDER PARASITIC CAPACITANCE CONDITIONS AND A CAPACITANCE-TO-VOLTAGE CONVERTER CIRCUIT - A method for converting a sensor capacitance under parasitic capacitance conditions and a capacitance-to-voltage (CV) converter circuit for converting a sensor capacitance under parasitic capacitance conditions are provided. The method comprises the step of using a two stage operational amplifier (op-amp) in non-unity-gain configuration, wherein the two stage op-amp is chosen to be unstable in unity-gain configuration for reducing power consumption.01-19-2012
20120009645CULTURE OF PLURIPOTENT AND MULTIPOTENT CELLS ON MICROCARRIERS - A method is disclosed for culturing pluripotent or multipotent cells in vitro, the method comprising attaching pluripotent or multipotent cells to a plurality of microcarriers to form microcarrier-cell complexes, and culturing the microcarrier-cell complexes in suspension culture in the presence of a ROCK inhibitor.01-12-2012
20120004430PRODUCTION OF HYDROXYMETHYLFURFURAL - The invention provides a process for making hydroxymethylfurfural comprising exposing a saccharide, e.g. glucose or fructose, to a metal complex of an N-heterocyclic carbene.01-05-2012
20120003689HYDROPHOBIC MAGNETIC PARTICLES - A process for making a particulate material comprising mesoporous particles having granules of a metal containing species in at least some of the pores thereof, said process comprising: allowing a compound of the metal to enter pores of hydrophobic mesoporous particles, said compound being thermally decomposable at a decomposition temperature to form a metal containing species and said particles being substantially thermally stable at said decomposition temperature; and heating the hydrophobic mesoporous particles having the compound in the pores thereof to the decomposition temperature so as to decompose the compound and to form the mesoporous particles having granules of the metal containing species in at least some of the pores thereof.01-05-2012
20120003259MOLECULE - We describe an Fve polypeptide being a fragment, homologue, variant or derivative of Fve protein, which comprises at least one biological activity of Fve protein. uses of such a polypeptide, etc, and nucleic acids encoding these, in the treatment and prevention of allergy and cancer are also disclosed.01-05-2012
20110319629TITANIUM COMPOUNDS AND PROCESS FOR CYANATION OF IMINES - The present invention relates to titanium catalysts for synthesis reactions produced by bringing a reaction mixture comprising a titanium alkoxide and a ligand in contact with water, wherein the ligand is represented by the general formula (e): wherein R12-29-2011
20110318831CHINESE HAMSTER APOPTOSIS-RELATED GENES - Provided is an isolated polypeptide comprising a 12-29-2011
20110318317CHINESE HAMSTER APOPTOSIS-RELATED GENES - Provided is an isolated polypeptide comprising a 12-29-2011
20110318316CHINESE HAMSTER APOPTOSIS-RELATED GENES - Provided is an isolated polypeptide comprising a 12-29-2011
20110311417Apparatus for Biopolymer Synthesis - The present invention relates to an apparatus for biopolymer synthesis wherein said apparatus comprises at least one support having a plurality of microwells and wherein said microwells comprise a porous substrate providing a surface area for biopolymer synthesis.12-22-2011
20110310387METHOD AND APPARATUS FOR TESTING MAGNETIC PROPERTIES OF MAGNETIC MEDIA - A method and apparatus for testing a magnetic medium. The method comprises applying a magnetic field of a time-varying strength; directing a polarized optical beam towards a portion of the medium that is in the magnetic field, wherein the optical beam is reflected by a surface of the medium at a point of incidence in the magnetic field; moving the medium relative to the optical beam so as to cause the point of incidence to repeatedly traverse each of a plurality of sectors along a track on the surface; obtaining a series of Kerr signal measurements of the reflected optical beam; grouping measurements into ensembles such that the measurements in an individual ensemble are those obtained while the point of incidence was in a corresponding one of the sectors; and determining at least one magnetic property of at least one of the sectors from the measurements in the corresponding ensemble.12-22-2011
20110303909PLANAR CONJUGATED COMPOUNDS AND THEIR APPLICATIONS FOR ORGANIC ELECTRONICS - The invention relates to organic semiconducting materials, methods for their preparation and organic electronic devices incorporating the said organic semiconducting materials. The organic semiconductors contain a compound of formula (I)12-15-2011
20110299519COOPERATIVE COMMUNICATION METHODS AND DEVICES - Cooperative communication methods for a wireless communication network (12-08-2011
20110296271METHOD OF COMMUNICATION - A method of communication comprising determining whether to use distributing coding between a source (S), relay (R) and destination (D), based on a predetermined transmission rate; if the determination is positive, determining a forward error correction scheme using distributed Alamouti space-time coding, wherein the scheme is determined based on the predetermined transmission rate, a channel signal-to-noise ratio (SNR) and a network topology; relaying coded data from the S to the D using the determined forward error correction.12-01-2011
20110296176METHOD AND SYSTEM FOR SHARING DATA - A method of sharing data between a first and a second party, a system for sharing data between a first and a second party and a computer readable data storage medium having stored thereon computer code means for instructing respective computer processors of a first party and a second party to execute a method of sharing data between the first and the second parties are provided. The method comprises the steps of performing respective randomization processes on data sets of the first and second parties; performing an exchange process between the first and second parties; performing an audit trail check process at the first and second parties respectively; and proceeding with performing a matching process at the first and second parties respectively only after a successful audit trail check by each party in the audit trail check process and the matching process is such that each party can determine whether the other party has provided a correct re-obfuscating number for determining common records between the first and second party.12-01-2011
20110294210Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.12-01-2011
20110293144Method and System for Rendering an Entertainment Animation - Systems and methods for rendering an entertainment animation. The system can comprise a user input unit for receiving a non-binary user input signal; an auxiliary signal source for generating an auxiliary signal; a classification unit for classifying the non-binary user input signal with reference to the auxiliary signal; and a rendering unit for rendering the entertainment animation based on classification results from the classification unit.12-01-2011
20110284926AVALANCHE PHOTODIODE STRUCTURE - An avalanche photodiode structure, to a method of fabricating an avalanche photodiode structure, and to devices incorporating an avalanche photodiode structure. The avalanche photodiode structure comprises a Ge doped region having a first polarity; a GaAs doped region having a second polarity opposite to the first polarity; and an undoped region between the Ge doped region and the GaAs doped region forming a heterojunction; wherein the undoped region comprises Ge and Al11-24-2011
20110284824LIGHT EMITTING DIODE STRUCTURE AND A METHOD OF FORMING A LIGHT EMITTING DIODE STRUCTURE - A light emitting diode structure and a method of forming a light emitting diode structure are provided. The structure comprises a superlattice comprising, a first barrier layer; a first quantum well layer comprising a first metal-nitride based material formed on the first barrier layer; a second barrier layer formed on the first quantum well layer; and a second quantum well layer comprising the first metal-nitride based material formed on the second barrier layer; and wherein a difference between conduction band energy of the first quantum well layer and conduction band energy of the second quantum well layer is matched to a single or multiple longitudinal optical phonon energy for reducing electron kinetic energy in the superlattice.11-24-2011
20110282897METHOD AND SYSTEM FOR MAINTAINING A DATABASE OF REFERENCE IMAGES - A method and system for maintaining a database of reference images, the database including a plurality of sets of images, each set associated with one location or object. The method comprises the steps of identifying local features of each set of images; determining distances between each local feature of each set and the local features of all other sets; identifying discriminative features of each set of images by removing local features based on the determined distances; and storing the discriminative features of each set of images.11-17-2011
20110275574METHOD OF INHIBITING PROLIFERATION OF HEPATIC STELLATE CELLS - There is presently provided a method of inhibiting proliferation of a hepatic stellate cell comprising directly down-regulating the hepatic stellate cell proliferation activity of connexin-43 in the hepatic stellate cell for the treatment of hepatic fibrosis or related disorder. This method primarily involves down regulating connexin-43 with agents such as Snai1, siRNAs, antisense RNA and DNA enzymes directed against the connexin-43 transcript. As a result the proliferation of activated hepatic stellate cells is down regulated.11-10-2011
20110269946PROTEIN SEPARATION DEVICE - The invention provides a protein separation device comprising a chaperone protein immobilized on a substrate. In one embodiment, the chaperone protein is an Hsp60 chaperone, preferably a group one chaperone, preferably GroEL. The invention also provides a method for isolating a protein from a biological sample using a protein separation device of the invention.11-03-2011
20110269812NOVEL BENZYLIDENE-INDOLINONE AND THEIR MEDICAL AND DIAGNOSTIC USES - The present invention relates generally to organic chemistry, biochemistry, pharmacology and medicine. More particularly, it relates to 3-benzylidene-indolin-2-one derivatives and their physiologically acceptable salts and prodrugs which modulate the activity of protein kinases (“PKs”), especially protein tyrosine kinase, and, therefore, are expected to exhibit a salutary effect against disorders related to abnormal PK activity. The present invention is further directed to methods of using of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of protein kinase-mediated diseases and disorders, such as cancer.11-03-2011
20110269226Microfluidic Continuous Flow Device for Culturing Biological Material - The present invention refers to a microfluidic continuous flow devices for culturing biological material each comprising a cultivation chamber being dimensioned to retain a biological material and having an inlet and an outlet to allow flow of a cultivation medium through the cultivation chamber. The present invention also refers to a method using the microfluidic continuous flow device of the present invention and the uses for these devices. In one example a microfluidic continuous flow device of the present invention is connected to a gradient generator.11-03-2011
20110268970MESOPOROUS NANOPARTICLES - The present invention provides a process for making mesoporous nanoparticles. The process comprises providing an acidic mixture comprising a fluorocarbon surfactant, a second surfactant and a silica precursor. The silica precursor is then reacted to form the mesoporous nanoparticles.11-03-2011
20110268711PANCREATIC STELLATE CELL SPECIFIC PROMOTER AND USES THEREOF - There is presently provided a method for effecting pancreatic stellate cell-specific gene expression comprising delivering a nucleic acid comprising a glial fibrillary acidic protein promoter operably linked to a coding sequence to a pancreatic stellate cell.11-03-2011
20110268274Authentication and Key Establishment in Wireless Sensor Networks - A wireless sensor network (WSN) and a method for establishing a communication key between devices in a WSN. The WSN comprises a first device configured for sending a request message to a second device, the request identifying at least a third device for communication with which a communication key is intended, a first random number, and a first authentication code generated using a first secret key shared between the first and second devices; the second device configured for authenticating the first authentication code based on the first secret key, for generating the communication key based on the first secret key, the first random number, and a second random number using a hash function, for sending an approval message to the third device, the approval message comprising, in encrypted form based on a second secret key shared between the second and third device, the communication key and the first and second random numbers; the third device configured for decrypting the communication key and the first and second random numbers based on the second secret key and for sending a notice message to the first device, the notice message comprising the first and the second random numbers; and the first device configured for recalculating the communication key, based on the first secret key and said received first and second random numbers using said hash function.11-03-2011
20110256574Microfluidic Continuous Flow Device - A microfluidic continuous flow device comprising a channel which comprises a first and a second area wherein the first area of the channel is a compartment which is defined by partitioning elements and the second area of the channel is a space outside the compartment; wherein through passages which are formed between the partitioning elements are dimensioned such as to retain a biological material and optionally a sustained release composition which can be comprised in the compartment within the compartment; wherein the channel has a first inlet to the compartment through which biological material can be introduced into the compartment; a second inlet for introducing a cultivation medium into a space of the channel arranged outside of the compartment, and an outlet. The present invention further refers to methods of using the devices of the present invention and kits comprising the microfluidic continuous flow devices of the present invention.10-20-2011
20110250649PCR-BASED METHOD OF SYNTHESIZING A NUCLEIC ACID MOLECULE - There is provided a method of synthesizing a nucleic acid molecule and in one aspect, the method comprises assembling a full length template nucleic acid molecule by PCR in a PCR reaction mixture comprising a set of assembly oligonucleotides having a first average melting temperature and a set of outer amplification primers having a second average melting temperature that is lower than the first average melting temperature, wherein said assembling comprises subjecting the PCR reaction mixture to a first annealing temperature that is higher than the second average melting temperature and; amplifying the full length template nucleic acid molecule by PCR in the PCR reaction mixture wherein said amplifying comprises subjecting the PCR reaction mixture to a second annealing temperature that permits annealing of the outer amplification primers to the full length template nucleic acid molecule.10-13-2011
20110250407METHOD OF MAKING A SUBSTRATE HAVING MULTI -LAYERED STRUCTURES - A method of making a substrate having multi-layered structures thereon, the method comprising the steps of (a) applying a mold having an imprint forming surface to the substrate to form an array of imprint structures that projects from the substrate; and (b) applying a lateral force that is substantially normal to said projecting imprint structures to cause said imprint structures to move angularly towards said substrate and thereby form a pattern of multi-layered structures thereon.10-13-2011
20110249776METHOD FOR DETERMINING AS TO WHETHER A RECEIVED SIGNAL INCLUDES A DATA SIGNAL - A method of determining as to whether a received signal includes a data signal is provided. The method provided includes determining a first value based on a cyclic auto-correlation of the received signal and determining a second value based on the cyclic auto-correlation of the received signal. The method provided further includes determining as to whether a received signal includes a data signal based on a comparison of the first value and the second value.10-13-2011
20110244659WAFER CUTTING METHOD AND A SYSTEM THEREOF - A method for cutting a semiconductor wafer by generating a crack within the wafer, and a system thereof, are provided. The method comprises irradiating a laser beam towards a surface of the wafer and converging the laser beam to form a focal point so that a focal volume defined by the focal point and a boundary of the laser beam within the wafer is formed. Energy encompassed within the focal volume causes the wafer located at the periphery of the focal volume to contract faster than the wafer located within the focal volume, thereby generating a crack within the wafer.10-06-2011
20110244002MESOPOROUS MATERIAL EXCIPIENTS FOR POORLY AQUEOUS SOLUBLE INGREDIENTS - The present invention encompasses formulations and methods for producing solid dispersions comprising mesoporous materials with poorly aqueous soluble active ingredients. The active ingredient is formed in the amorphous state and entrapped in the nanosized pores of the mesoporous excipients using a co-spray drying process. The pore walls of mesoporous channels stabilize the amorphous form of active ingredient against re-crystallization. The amorphous active ingredient entrapped in mesoporous channels exhibits good stability during extended storage under stress test conditions and possesses significantly enhanced dissolution rates.10-06-2011
20110243851GLUCOSE-PEG CONJUGATES FOR REDUCING GLUCOSE TRANSPORT INTO A CELL - There is provided a glucose-PEG conjugate comprising a PEG moiety conjugated to a linear glucose moiety at the C1 position of the glucose moiety. The glucose-PEG conjugate may be used to reduce glucose transport into a cell and may be used to treat a proliferative disorder.10-06-2011
20110243821CARBON DIOXIDE REDUCTION - The invention provides a process for reducing carbon dioxide comprising the step of exposing the carbon dioxide to a silane in the presence of an N-heterocyclic carbene (NHC) or a carboxylate thereof or both, to produce a methylsilyl ether.10-06-2011
20110243197TWO-DIMENSIONAL CODE SPREADING FOR INTERLEAVED FDMA SYSTEM - A transmitter comprises a first spreading unit configured to multiply each of multiple data symbols with a first spreading code sequence of a first spreading factor; a compression and repetition unit configured to compress output signals of the first spreading unit in time domain and repeat the compressed signal L times (where L is a natural number greater than or equal to 2); a phase modulation unit configured to multiply the compressed and repeated signal with a user dependent phase and output a data block consisting of L sub-blocks; a second spreading unit configured to replicate the data block according to a second spreading factor and multiply each set of the replicated sub-blocks with a second spreading code sequence of the second spreading factor to produce a two-dimensionally spread signal; and a wireless transmission unit configured to transmit the two-dimensionally spread signal using a single-carrier transmission scheme.10-06-2011
20110237000Method for detecting an analyte molecule - The invention relates to a method for detecting the presence or amount of an analyte, said method comprising (a) coupling the analyte to a carrier molecule, wherein the carrier molecule is larger in size, electrically charged and/or polar, to form an analyte:carrier molecule complex; (b) contacting the analyte:carrier molecule complex of (a) with an analyte-binding molecule coupled to a semiconducting nanostructure; and (c) determining the change in conductance upon binding of the analyte:carrier molecule complex to the analyte-binding molecule and correlating the determined change in conductance to the presence or amount of the analyte. Alternatively, the analyte:carrier molecule complex of (a) is immobilized on the nanostructure and the immobilized analyte:carrier molecule complex is contacted with the analyte-binding molecule.09-29-2011
20110236639METHOD OF MAKING AN IMPRINT ON A POLYMER STRUCTURE - There is disclosed a method of making an imprint on a polymer structure comprising the steps of: a) providing an imprinted substrate mold having a defined imprinted surface pattern on a first side and a defined imprinted surface pattern on a second side, opposite to the first side; b) pressing a polymer structure against the first side of the imprinted substrate mold to form an imprint thereon; and c) pressing another polymer structure against the second side of the imprinted substrate mold to form an imprint thereon.09-29-2011
20110233468PROCESS OF FORMING A CADMIUM AND SELENIUM CONTAINING NANOCRYSTALLINE COMPOSITE AND NANOCRYSTALLINE COMPOSITE OBTAINED THEREFROM - Provided is a process of forming a Cd and Se containing nanocrystalline composite. The nanocrystalline composite has a composition of one of (a) Cd, M, Se, (b) Cd, Se, A, and (c) Cd, M, Se, A, with M being an element of group (12) of the PSE other than Cd and A being an element of group (16) of the PSE other than O and Se. In one embodiment in a suitable solvent a solution of the element Cd, or a precursor thereof, and, where applicable, of M, or a precursor thereof is formed. To the solution the element Se and, where applicable, A is added and thereby a reaction mixture formed. The reaction mixture is heated for a sufficient period of time at a temperature suitable for forming the Cd and Se containing nanocrystalline composite and then the reaction mixture is allowed to cool. Finally the Cd and Se containing nanocrystalline composite isolated. In another embodiment the reaction mixture is formed by adding into a suitable solvent the element Cd, or a precursor thereof, Se, where applicable M and where applicable A. In this embodiment the reaction mixture is heated and water formed during the process is being removed.09-29-2011
20110217350SUBSTRATE HAVING A SURFACE FOR INHIBITING ADHESION OF A TARGET CELL THEREON AND A METHOD OF PREPARING THE SAME - A substrate having a surface for inhibiting adhesion of a target cell thereon, the substrate comprising an array of generally longitudinal projections having a longitudinal axis that extends from the surface of said substrate and having an aspect ratio of at least 2.5, wherein adjacent projections of said array are configured on the substrate such that the projections at least partially inhibit adhesion of a target cell thereon.09-08-2011
20110211786SILICON-BASED ELECTRO-OPTIC DEVICE - In an electro-optic device, a stack structure including a first silicon layer of a first conductivity type and a second silicon layer of a second conductivity type has a rib waveguide shape so as to form an optical confinement area, and a slab portion of a rib waveguide includes an area to which a metal electrode is connected. The slab portion in the area to which the metal electrode is connected is thicker than a surrounding slab portion. The area to which the metal electrode is connected is set so that a range of a distance from the rib waveguide to the area to which the metal electrode is connected is such that when the distance is changed, an effective refractive index of the rib waveguide in a zeroth-order mode does not change.09-01-2011
20110211549MULTIPLE ACCESS COMMUNICATION SYSTEM - A multiple access communication system is disclosed herein. In a described embodiment, there is disclosed a method of allocating system bandwidth of the communication system and the method comprises, at step (09-01-2011
20110210891Communication Device And Method For Controlling An Antenna Arrangement - A communication device is described comprising an antenna arrangement, an orientation determining device configured to determine the orientation of the antenna arrangement, and a controller configured to control the directivity of the antenna arrangement based on the determined orientation of the antenna arrangement.09-01-2011
20110206657ANTIBODIES BINDING TO AN INTRACELLULAR PRL-1 OR PRL-3 POLYPEPTIDE - We provide an antibody capable of 08-25-2011
20110205929 METHOD OF OPTIMISING BANDWIDTH ALLOCATION IN A WIRELESS COMMUNICATION NETWORK - A method for communication (08-25-2011
20110193183NANOWIRE SENSOR, NANOWIRE SENSOR ARRAY AND METHOD OF FABRICATING THE SAME - A method of fabricating a sensor comprising a nanowire on a support substrate with a first semiconductor layer arranged on the support substrate is disclosed. The method comprises forming a fin structure from the first semiconductor layer, the fin structure comprising at least two supporting portions and a fin portion arranged there between; oxidizing at least the fin portion of the fin structure thereby forming the nanowire being surrounded by a first layer of oxide; and forming an insulating layer above the supporting portions; wherein the supporting portions and the first insulating layer form a microfluidic channel. A nanowire sensor is also disclosed. The nanowire sensor comprises a support substrate, a semiconducting fin structure arranged on the support substrate, the fin structure comprising at least two semiconducting supporting portions and a nanowire arranged there between; and a first insulating layer on a contact surface of the supporting portions; wherein the supporting portions and the first insulating layer form a microfluidic channel.08-11-2011
20110192726DEVICE AND METHOD FOR DETECTION OF ANALYTE FROM A SAMPLE - There is presently provided a device for detecting an analyte particle in a sample. The device comprises a chamber having an interior surface upon which is located an electrode array. The electrode array comprises pairs of electrodes, each pair having an inner electrode and an outer electrode that substantially surrounds the inner electrode. Each pair of electrodes is coated with a capture molecule that recognises and binds the analyte particle that is to be identified and quantified. The device uses a combination of dielectrophoresis and impedance measurements to capture and measure analyte particles from a sample.08-11-2011
20110191350METHOD AND SYSTEM FOR CONCENTRATION DETECTION - A method and system for concentration detection. The method for concentration detection comprises the steps of extracting temporal features from brain signals; classifying the extracted temporal features using a classifier to give a score x08-04-2011
20110188859WDM-PON ARCHITECTURE BASED ON EXTERNALLY SEEDED OPTICAL SOURCE - A wavelength-division-multiplexed passive optical network (WDM PON) comprising: a remote node (RN) comprising a light source for generating a seeding signal; and one or more optical network units (ONUs), each ONU comprising a laser source configured for receiving a portion of the seeding light signal from the RN.08-04-2011
20110188557METHOD, DEVICE AND COMPUTER READABLE MEDIUM FOR DETERMINING WHETHER TRANSMISSION SIGNALS ARE PRESENT IN RECEIVED SIGNALS - A method is provided for determining whether transmission signals are present in received signals, the method comprising: receiving a first signal via a first radio resource; receiving a second signal via a second radio resource; determining whether a first transmission signal is present in the received first signal based on the received second signal; and determining whether a second transmission signal is present in the received second signal based on the received first signal.08-04-2011
20110182336METHOD FOR DETERMINING A SIGNAL VECTOR AND DETECTION CIRCUIT - A method for determining a signal vector comprising a plurality of components from a received signal vector is provided comprising generating an estimation of the signal vector; determining a channel matrix characterizing the communication channel via which the signal vector was received; carrying out a plurality of determination iterations based on the channel matrix, wherein for each iteration a first set of possible sub-vectors of the signal vector is determined based on a second set of possible sub-vectors for the previous iteration and from the first set of possible sub-vectors, a number of sub-vectors is selected based on the distance of the sub-vectors to the estimated signal vector according to a pre-selected metric to form a strict subset of the first set as the second set of possible sub-vectors for the iteration; determining the signal vector based on a possible sub-vector for the last iteration.07-28-2011
20110178040METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS - There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.07-21-2011
20110176534COMMUNICATION DEVICE AND METHOD FOR SYNCHRONISATION - A communication device is provided, the communication device comprising a receiving circuit configured to receive a message from another communication device; a time base circuit providing a time base signal that specifies a plurality of time periods; a determining circuit configured to determine, based on an expected reception time of the message and a reception time of the message, a parameter value characterizing a time base offset between the communication device and the other communication device; an offset generating circuit configured to generate a time period offset value specifying a time offset from a point in time, the time period offset value corresponding to a number of time periods from the plurality of time periods, wherein the number of time periods is determined according to the parameter value.07-21-2011
20110171183Markers of Induced Pluripotent Stem Cells - The disclosure relates to the expression of podocalyxin-like protein (PODXL) on the surface of induced pluripotent stem cells and particularly, although not exclusively, to the use of PODXL as a marker of induced pluripotent stem cells.07-14-2011
20110167346METHOD AND SYSTEM FOR CREATING A MULTI-MEDIA OUTPUT FOR PRESENTATION TO AND INTERACTION WITH A LIVE AUDIENCE - A method and system for creating a multi-media output for presentation to and interaction with a live audience. The method comprises the steps of playing a substantially continuous multi-media clip using a multi-media unit for substantially real-time display on a display unit; receiving, during the substantially real-time display of the multi-media clip, multi-media content from one or more persons in the live audience via one or more multi-media devices, wherein said multi-media devices are remotely coupled to the multi-media unit; providing a user interface of the multi-media unit for accessing and manipulating said received multi-media content; and incorporating at least a portion of said received multi-media content into the substantially continuous multi-media clip using the multi-media unit.07-07-2011
20110165218Therapeutic Bone Growth and Regeneration - The use of Herapan Sulphate 2 (HS-2) in therapeutic bone growth and regeneration is described. Herapan Sulphate 2 was identified as a variant of Heparan Sulphate purified from embryonic day (E10) of murine neuroepithelia.07-07-2011
20110165132Heparan Sulphate Which Binds BMP2 - The invention relates to heparan sulphate GAGs obtained by affinity chromatography using the heparin-binding domain of BMP2. The GAGs were obtained from osteoblast extracellular matrix and from a commercially available heparan sulfate (Celsus HS).07-07-2011
20110159071Isolation and Identification of Glycosaminoglycans - The isolation and identification of glycosaminoglycans capable of binding to proteins having a heparin-binding domain is disclosed, as well as the use of the glycosaminoglycans isolated in the growth and/or development of tissue.06-30-2011
20110151173INORGANIC GRADED BARRIER FILM AND METHODS FOR THEIR MANUFACTURE - The present invention refers to a graded barrier film comprising a layered structure, wherein the layered structure comprises a first layer consisting of metal oxide; an intermediate layer consisting of metal nitride or metal oxynitride which is arranged on the first layer; and a third layer consisting of a metal oxide which is arranged on the intermediate layer. The present invention further refers to a sputtering method for manufacturing this graded barrier film and a device encapsulated with this graded barrier film.06-23-2011
20110149407RUGGED VARIABLE FOCUS LIQUID LENSES AND ACTUATORS FOR ACTUATION OF LIQUID LENSES - An optical device (06-23-2011
20110149285OPTICAL RESONATOR AND OPTICAL SENSING SYSTEM COMPRISING THE SAME - An embodiment of the invention relates to an optical resonator. The optical resonator includes an input optical waveguide and a closed loop coupled to the input optical waveguide. The closed loop is adapted to receive light from the input optical waveguide, wherein the closed loop includes at least one hole formed within a portion of the closed loop.06-23-2011
20110146364METHOD AND APPARATUS FOR FORGING - An apparatus (06-23-2011
20110143433Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.06-16-2011
20110135749LOW SHRINKAGE MULTIFUNCTIONAL SSQ RESINS - The present invention relates to low shrinkage multi functionalized silsesquioxane (SSQ) derivatives, to nanocomposite materials comprising these SSQ's and to the use of the nanocomposite material as a polymerizable resin in biologically compatible materials.06-09-2011
20110132449MULTILAYER FILM FOR ENCAPSULATING OXYGEN AND/OR MOISTURE SENSITIVE ELECTRONIC DEVICES - The present invention refers to a multilayer barrier film capable of encapsulating a moisture and/or oxygen sensitive electronic or optoelectronic device, the barrier film comprises at least one nanostructured layer comprising reactive nanoparticles capable of interacting with moisture and/or oxygen, the reactive nanoparticles being distributed within a polymeric binder, and at least one ultraviolet light neutralizing layer comprising a material capable of absorbing ultraviolet light, thereby limiting the transmission of ultraviolet light through the barrier film06-09-2011
20110129944WATER-SOLUBLE NANOCRYSTALS AND METHODS OF PREPARING THEM - Disclosed is a water soluble nanocrystal having a core comprising at least one metal M1 selected from an element of subgroup IIb, subgroup VIIa, subgroup VI11a, subgroup 1b, subgroup IV, main group II or main group III of the periodic system of the elements (PSE), at least one element A selected from an element of the main group V or VI of the periodic system of the elements, wherein a capping reagent is attached to the surface of the core of the nanocrystal, and wherein the capping reagent forms a host guest complex with a water soluble host molecule. Also disclosed is a water soluble nanocrystal having a core comprising at least one metal M1 selected from an element of subgroup I1b, subgroup VI1a, subgroup VI11a, subgroup 1b, subgroup IV, main group II or main group III of the periodic system of the elements (PSE), and at least one element A selected from an element of the main group V or VI of the periodic system of the elements, wherein a capping reagent is attached to the surface of the core of the nanocrystal, and wherein the capping reagent is covalently linked to a water soluble host molecule. Also disclosed is a water soluble nanocrystal having a core comprising at least one metal M1 selected from an element of subgroup I1b, subgroup VI1a, subgroup VI11a, subgroup 1b, subgroup IV, main group II or main group III of the periodic system of the elements (PSE), wherein a capping reagent is attached to the surface of the core of the nanocrystal, and wherein the capping reagent forms a host guest complex with a water soluble host molecule. Finally, compositions and uses of such nanocrystals are disclosed.06-02-2011
20110129927CHINESE HAMSTER APOPTOSIS-RELATED GENES - Provided is an isolated polypeptide comprising a 06-02-2011
20110129924Porous Polymeric Articles - Porous polymeric articles, and more specifically, porous polymeric articles for tissue engineering and organ replacement, are described. In some embodiments, methods described herein include use of a polymer-solvent system (e.g., phase inversion) to generate porosity in a structure. The process may include formation of a structure precursor material including a first crosslinkable component and a second component that can be precipitated in a precipitation medium. The structure precursor material may be shaped into a three-dimensional shape by a suitable technique such as three-dimensional printing. Upon shaping of the structure precursor material, at least a portion of the first component may be crosslinked. The structure may then be contacted with a precipitation medium to remove the precursor solvent from the structure, which can cause the second polymer component to precipitate and form a porous structure containing a network of uniform pores. In some embodiments, the porous structure is constructed and arranged for use as a template for ultrafiltration, cell growth, and/or for forming complex, biomimetic, porous biohybrid organs, where living cells can be immobilized and perform their normal physiological functions.06-02-2011
20110129919Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.06-02-2011
20110124831SELF-ASSEMBLED OLEFIN POLYMERIZATION CATALYST - The present invention relates to a self-assembled olefin polymerization catalyst comprising a transition metal compound according to formula (I) L05-26-2011
20110124755Polyisocyanurates - The invention relates to a polyisocyanurate comprising isocyanurate rings linked by linker groups coupled to the nitrogen atoms of said rings. The polyisocyanurate may be microporous or mesoporous or both microporous and mesoporous.05-26-2011
20110122976METHOD AND SYSTEM FOR DETERMINING WHETHER A TRANSMITTED DATA SIGNAL COMPRISING A CYCLIC PREFIX IS PRESENT IN A RECEIVED SIGNAL - A method for determining whether a transmission signal comprising a cyclic prefix is present in a received signal is described which includes determining a plurality of received signal values from the received signal; forming a plurality of different pairs of the received signal values based on a predefined periodicity of the cyclic prefix; determining a correlation term value for each of the plurality of pairs of the received signal values; and determining whether a data signal is present in the received signal based on a combination of the correlation term values.05-26-2011
20110122504VARIABLE FOCUS MICROLENS - A microlens chip comprises a variable focus fluidic microlens and actuator. The actuator varies the pressure in a fluidic channel in the microlens chip which is coupled to an aperture opening containing the microlens. Applying an electric field to the actuator creates changes in fluid pressure in the fluidic channel, which in turn changes the radius of curvature (i.e., focal length) of the fluidic microlens.05-26-2011
20110116093SENSOR CHIP FOR BIOLOGICAL AND CHEMICAL SENSING - A sensor chip comprising: 05-19-2011
20110114970LIGHT EMITTING DIODE STRUCTURE, A LAMP DEVICE AND A METHOD OF FORMING A LIGHT EMITTING DIODE STRUCTURE - A light emitting diode structure, a lamp device and a method of forming a light emitting diode structure are provided. The structure has a substrate coated with a first reflective material; an electrode coated with a second reflective material, one or more layers of light emitting material, the layers disposed between the substrate and electrode; wherein in use, the first reflective material and second reflective material reflects light out of the structure via at least one light emitting surface and in a direction away from the electrode.05-19-2011
20110112310AZIRIDINE SYNTHESIS - The invention relates to a process for making an aziridine. wherein an aldehyde, a nitroso compound and a Michael acceptor are reacted in the presence of an N-heterocyclic carbene (NHC) catalyst.05-12-2011
20110111711High Efficiency Linear Transmitter - A highly efficient linear transmitter uses a control module to compare an input signal with a threshold. The transmitter includes one or more power amplifiers (05-12-2011
20110111498Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.05-12-2011
20110105942SYSTEM AND METHOD FOR DETECTING SKIN PENETRATION - A system and method for detecting skin penetration. The system comprises an invasive component for penetrating the skin; a dummy electrode for making contact with the surface of the skin; at least one penetrating electrode disposed in the invasive component; and a Wheatstone bridge circuit; wherein a resistance across the dummy electrode and the penetrating electrode constitutes one of the resistive legs of the Wheatstone bridge circuit and skin penetration of the invasive component is detected based on a differential output voltage from the Wheatstone bridge circuit.05-05-2011
20110103545COMPUTED TOMOGRAPHY METHOD AND APPARATUS FOR CENTRE-OF-ROTATION DETERMINATION - A method and apparatus is disclosed for determining the central ray of scanning an object on a detector in a computer tomography system. The method comprises producing a fan beam of x-rays at a fixed x-ray source and detecting the x-rays at the detector. The scanning projection data of the object under examination is received and the object is rotated under examination using a manipulator. After calculating the opposite projection pixel position and projection angle for each pixel, a mismatching is measured between the grey levels of all pixels and their calculated opposite projection pixels with a set of assumed central ray, and identifying the minimum of the measurement as the true central ray.05-05-2011
20110102079High efficiency linear amplifier - A high efficiency linear amplifier is disclosed. The amplifier comprises an input module having an input coupled to receive an input signal, a first output configured to provide a first signal component, and a second output configured to provide a second signal component. The amplifier also comprises a switching module having a switch input coupled to receive a switch signal, a first input coupled to the first output of the input module, a second input coupled to the second output of the input module, and at least a first output configured to provide a first composite signal. The amplifier further comprises an amplifier module having at least a first input coupled to the first output of the switching module and at least a first output, wherein the first and second signal components comprise constant envelope phase varying signals having different phase relationships and which correspond to the input signal, and wherein the first composite signal comprises temporally sequenced portions of the first and second signal components.05-05-2011
20110098218MODULATORS OF STAT3 SIGNALLING - The invention relates to methods for identifying compounds which modulate the interaction between STAT3 an SP1. A peptide is provided which is able to bind STAT3 and interfere with the interaction of STAT3 and SP1. The invention provides methods for identifying compounds which are capable of binding to the peptide and thus release interference with the interaction between STAT3 and SP1, as well as methods for identifying inhibitors and enhancers of the STAT3 SP1 interaction. Compounds identified by the methods of the invention are useful in the repression or stimulation of appetite in a patient, useful for the treatment of leptin resistance, obesity and anorexia.04-28-2011
20110095324METHOD FOR FABRICATING MICRO AND NANO STRUCTURES - A method of forming an array of selectively shaped optical elements on a substrate, the method including the steps of providing the substrate, the substrate having an optical layer placed thereon; placing a layer of particles on the optical layer; performing an etching cycle. The cycle includes the steps of: etching the layer of particles, using a first etching process so as to reduce the size of the particles within the layer, then; simultaneously etching the optical layer and the layer of particles, using a second etching process, the further reducing particles forming a mask over areas of the optical layer to create discrete optical elements from the optical layer.04-28-2011
20110092518Antifouling Compounds And Use Thereof - The present invention relates to the use of compounds which have the following general formula (I), wherein R04-21-2011
20110091464NOVEL PEPTIDES AND PROTEIN AND USES THEREOF - The present invention relates to a novel gene encoding a protein termed Coiled Coil Domain Containing 95 (CCDC95) or a peptide fragments thereof. The present invention also relates to the use of CCDC95 in Modulation of RGK small binding protein via altering concentration or sub-cellular localisation of RGK small binding protein with CCDC95 or a peptide fragments thereof.04-21-2011
20110084669POWER SUPPLY DEVICE AND SYSTEM - A power supply device and system have an electrically polarized element in which a remnant electrical polarization is formed and retained. Electrodes are formed on the electrically polarized elements and the remnant electrical polarization generates an electrical potential on the electrodes. Electrical circuits are coupled to the electrically polarized element to control the external electric charges attracted and distributed on the electrodes, for establishing the electrical potential on the electrodes. The electrodes can output electric currents by controlling the external electric charges distribution. The electrically polarized element may be made of ferroelectric material, including a ferroelectric bulk ceramic, ferroelectric multilayer ceramic, ferroelectric single crystal, ferroelectric thin film, ferroelectric thick film and ferroelectric polymer, and all the other materials with electric polarization retained therein. Power supply devices and systems made according to the present invention have very long standby time, small in size and efficient for many applications including RF systems.04-14-2011
20110077538ELECTROCARDIOGRAM SIGNAL PROCESSING SYSTEM - According to embodiments of the present invention, an electrocardiogram signal processing system is provided which includes: a wavelet transformation unit comprising a plurality of outputs, each output being connected to one of a plurality of scales, wherein the wavelet transformation unit is adapted to transform an input electrocardiogram signal into a set of wavelets, each wavelet being output to one of the scales; a plurality of signal processing blocks, each of the signal processing blocks coupled to a respective output of the wavelet transformation unit and configured to receive and process the wavelet from the respective output, wherein the signal processing blocks provide processing functions which differ from one another.03-31-2011
20110073811COATED WATER SOLUBLE NANOPARTICLES - Nanoparticles and methods of making nanoparticles are provided. The nanoparticles may include semiconductor nanocrystals. A shell may encapsulate a nanoparticle core, and the shell may include non-organic material and may be silica. The shell may also include additional species such as PEG. In some embodiments, a passivation layer is in contact with the core.03-31-2011
20110070208HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF - There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.03-24-2011
20110064117METHODS FOR NETWORK THROUGHPUT ENHANCEMENT - A method for transmitting OFDM symbols by a plurality of ad-hoc radio communication devices in an ad-hoc radio communication devices' group is provided. The method includes a first ad-hoc radio communication device of the ad-hoc radio communication devices' group transmitting a first OFDM symbol in a first frequency sub-range of a frequency range selected for transmission in accordance with a frequency hopping pattern, the frequency range comprising a plurality of frequency sub-ranges, and in the same transmission time period, a second ad-hoc radio communication device of the ad-hoc radio communication devices' group transmitting a second OFDM symbol in a second frequency sub-range of the frequency range, wherein the second frequency sub-range is different from the first frequency sub-range.03-17-2011
20110062972METHOD OF DETERMINING A SENSITIVITY OF A BIOSENSOR ARRANGEMENT, AND BIOSENSOR SENSITIVITY DETERMINING SYSTEM - According to an embodiment of the present invention, a method of determining or adjusting the sensitivity of a biosensor arrangement comprising at least one field effect biosensor is provided, each of the at least one field effect biosensor comprising: a semiconductor substrate comprising a source region, a drain region and a channel region disposed between the source region and the drain region; a gate isolation layer covering the channel region; and a reference electrode disposed over the gate isolation layer such that a electrolytic solution to be sensed can be provided between the reference electrode and the gate isolation layer. The method comprises the following processes carried out for each field effect biosensor: providing an electrolytic solution between the reference electrode and the gate isolation layer; applying a source/drain voltage between the source region and the drain region; varying a reference voltage supplied to the reference electrode over a voltage range; measuring a resulting drain current while varying the reference voltage in order to obtain a corresponding drain current function; and determining the sensitivity of the field effect biosensor based on the reference voltage supplied to the reference electrode and the corresponding drain current function.03-17-2011
20110053882METHODS AND COMPOUNDS FOR PREVENTING AND TREATING A TUMOUR - The invention relates to a method of preventing, inhibiting, arresting or reversing tumourigenesis in a cell as well as a method of inducing apoptosis in a tumour cell. The method includes increasing the amount and/or the activity of a DACT protein, or a functional fragment thereof, in the cell. Also provided is a pharmaceutical composition that comprises a compound of general formula (I), wherein A is CH or N, R03-03-2011
20110053095MANUFACTURING METHOD OF PLANAR OPTICAL WAVEGUIDE DEVICE WITH GRATING STRUCTURE - A method for manufacturing a planar optical waveguide device including a core of which a top face is provided with a groove section filled with a groove section filler made of a low refractive index material having a refractive index lower than that of the core, the method including; a first high refractive index material layer forming step of forming a high refractive index material layer; a low refractive index material layer forming step of forming a low refractive index material layer made of the low refractive index material on the high refractive index material layer; a groove section filler forming step of forming the groove section filler by trimming both lateral portions of the low refractive index material layer; and a second high refractive index material layer forming step of forming a high refractive index material layer so as to fill the both sides of the lateral portions of the groove section filler.03-03-2011
20110053050METHOD OF FUNCTIONALIZING A CARBON MATERIAL - The present invention relates to a method of functionalizing a carbon material. A carbon material is contacted with a carboxylic acid, whereby a mixture is formed. The mixture is heated for a suitable period of time at a temperature below the thermal decomposition temperature of the carbon material.03-03-2011
20110049735MANUFACTURING METHOD OF PLANAR OPTICAL WAVEGUIDE DEVICE WITH GRATING STRUCTURE - A method for manufacturing a planar optical waveguide device of which a core includes a plurality of alternatively arranged fin portions and valley portions to form a grating structure, in which the core widths of the valley portions vary along the longitudinal direction, the method including: a high refractive index material layer forming step of forming a high refractive index material layer; a photoresist layer forming step of forming a photoresist layer on the high refractive index material layer; a first exposure step of forming shaded portions on the photoresist layer using a phase-shifting photomask; a second exposure step of forming shaded portions on the photoresist layer using a binary photomask; a development step of developing the photoresist layer; and an etching step of etching the high refractive index material layer using the photoresist pattern resulted from the development step.03-03-2011
20110047630METHOD AND SYSTEM FOR TAMPER PROOFING A SYSTEM OF INTERCONNECTED ELECTRONIC DEVICES - A method and system for tamper proofing a system of interconnected electronic devices. The method comprises splitting embedded software of each electronic device into at least two executable parts, a stationary part residing in memory of said each electronic device and a non-stationary part residing in memory of another electronic device.02-24-2011
20110046945METHOD AND DEVICE OF BITRATE DISTRIBUTION/TRUNCATION FOR SCALABLE AUDIO CODING - Embodiments of the invention provides a method and device for assigning bitrates to a plurality of channels in a scalable audio encoding/truncation process. Different bitrates are assigned to different channels in the scalable audio encoding/truncation process.02-24-2011
20110045094ENCAPSULATED QUANTUM DOT - A particle comprising a quantum dot encapsulated by an amphiphilic polymer. These particles are suitable for use in biological and biomedical research and may emit fluorescence and may be water-soluble and biocompatible. The encapsulated quantum dot may be introduced into a living system without any substantial toxic or immunological effects.02-24-2011
20110044376METHOD OF TRANSMITTING DATA TO A RECEIVER - A method of transmitting data to a receiver, wherein the data is transmitted using a plurality of sub-carriers, is provided. The method provided includes determining, for each sub-carrier and for each of a plurality of combinations of the sub-carrier and an antenna of a plurality of antennas to be used for transmitting the data, a transmission characteristic of a transmission of the sub-carrier using the antenna; and selecting, for each sub-carrier, an antenna of the plurality of antennas to be used for the transmission of the sub-carrier based on the transmission characteristic of the transmission of the sub-carrier between the antenna and the receiver.02-24-2011
20110042720Magneto-Electric Field Effect Transistor for Spintronic Applications - The present invention is directed to a magneto-electric field effect transistor comprising a channel region, a source connected to one side of the channel region and adapted to inject electrons into the channel region, a drain connected to the opposite side of the channel region and adapted to detect spin polarized electrons; and a gate comprising at least one magnetic double pair element comprising four magnetic elements each magnetic element being adapted to induce a magnetic field into the channel region, wherein the total induced magnetic field of the magnetic double pair element is controllable to be substantially zero, and wherein the gate is further adapted to induce an electrical field into the channel region.02-24-2011
20110039715INFLUENZA B VIRUS DETECTION METHOD AND KIT THEREFOR - The invention provides oligonucleotide(s) for simple, specific and/or sensitive test(s) for the presence of Influenza virus. In particular, the present invention provides oligonucleotide(s) for test(s) for the Influenza B virus. Kit(s) comprising the oligonucleotide(s) for use as probe(s) and/or primer(s) useful in the test(s) are also provided.02-17-2011
20110034700CHIRAL BISOXAZOLINE CATALYSTS - The present invention describes a heterogeneous chiral catalyst comprising a heterogeneous chiral catalyst precursor complexed with a metal species. The precursor comprises a chiral bisoxazoline group coupled to an inorganic substrate. The heterogeneous chiral catalyst may be capable of catalysing a chemical reaction, for example cyclopropanation, and the chemical reaction may be capable of generating a chiral product.02-10-2011
20110033368METHODS OF FORMING A NANOCRYSTAL - Methods of forming a nanocrystal are provided. The nanocrystal may be a binary nanocrystal of general formula M1A or of general formula M1O, a ternary nanocrystal of general formula M1M2A, of general formula M1AB or of general formula M1M2O or a quaternary nanocrystal of general formula M1M2AB. M1 is a metal of Groups II-IV, Group VII or Group VIII of the PSE. A is an element of Group VI or Group V of the PSE. O is oxygen. A homogenous reaction mixture in a non-polar solvent of low boiling point is formed, that includes a metal precursor containing the metal M1 and, where applicable M2. For an oxygen containing nanocrystal the metal precursor contains an oxygen donor. Where applicable, A is also included in the homogenous reaction mixture. The homogenous reaction mixture is under elevated pressure brought to an elevated temperature that is suitable for forming a nanocrystal.02-10-2011
20110031658METHOD OF REDUCING THE DIMENSION OF AN IMPRINT STRUCTURE ON A SUBSTRATE - A method of reducing the dimension of an imprint structure on a substrate, the method comprising the steps of: 02-10-2011
20110030874LOW TEMPERATURE METHOD OF BONDING SUBSTRATES HAVING AT LEAST ONE SURFACE THAT INCLUDES A LAYER OF SU8 - A method of bonding at least two substrates, each substrate having at least one surface that includes a layer of SU8, said method comprising soft baking at least a portion of the layer of SU8 of the first and second substrates, exposing at least the portion of the layer of SU8 of the first and second substrates to ultraviolet (UV) radiation to cross-link at least the portion of the layer of SU8 of the second substrate to a suitable degree, post exposure baking at least the portion of the layer of SU8 of the first substrate at a temperature greater than or equal to 20 degree Celsius (° C.) and less than or equal to 50 degree Celsius (° C.) to cross-link at least the portion of the layer of SU8 of the first substrate to a suitable degree. The method also includes compressing the portion of the cross-linked layer of SU8 of the first substrate against the portion of the cross-linked layer of SU8 of the second substrate at a suitable starting temperature (T02-10-2011
20110023692APPARATUS AND METHOD FOR TRANSFORMING AN INPUT SOUND SIGNAL - An apparatus for transforming an input sound signal comprises a synthesiser which manipulates, in accordance with a manipulation parameter, a pitch deviation envelope to derive a manipulated pitch deviation envelope. A filter transforms the input sound signal from a resampling of the input sound signal with respect to the manipulated pitch deviation envelope. The manipulation parameter may be a user-defined peak pitch deviation of an output sound signal. Another apparatus for transforming an input sound signal comprises a synthesiser which manipulates, in accordance with a manipulation parameter, a pitch deviation envelope selected with reference to the manipulation parameter to derive a manipulated pitch deviation envelope.02-03-2011
20110020317BREAST TUMOUR GRADING - We describe a method of assigning a grade to a breast tumour, which grade is indicative of the aggressiveness of the tumour, the method comprising detecting the expression of a gene selected from the genes set out in Table D1 (SWS Classifier 0).01-27-2011
20110018138NANO-INTERCONNECTS FOR ATOMIC AND MOLECULAR SCALE CIRCUITS - A method for forming interconnects in a substrate, the substrate comprising a semiconductor layer on an oxide layer forming a silicon-on-oxide substrate, the method comprising forming a plurality of holes into the substrate to the semiconductor layer, and metalizing the plurality of holes to form the interconnects.01-27-2011
20110018053MEMORY CELL AND METHODS OF MANUFACTURING THEREOF - A memory cell is provided. The memory cell comprises a first wire shaped channel structure; and a charge trapping structure surrounding the perimeter surface of the first wire shaped channel structure, the charge trapping structure comprising two charge trapping partial to structures, wherein each charge trapping partial structure is formed of a different material capable of storing electrical charges. Methods of manufacturing the memory cell are also provided.01-27-2011
20110015402RECIRCULATING REACTOR - The invention provides a recirculating reactor for converting a substrate to a product. The reactor comprises a reaction chamber and a recirculation system, said recirculation system comprising a separator. The reaction chamber contains a catalyst, and comprises a chamber body, a chamber inlet and a chamber outlet. The recirculation system is adapted for recirculating liquid from the chamber outlet to the chamber inlet, and the separator is used for separating a by-product from the liquid.01-20-2011
20110014693Microcarriers For Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.01-20-2011
20110014692METHOD OF DERIVING PROGENITOR CELL LINE - We disclose a method comprising: (a) providing an embryonic stem (ES) cell; and (b) establishing a progenitor cell line from the embryonic stem cell; in which the progenitor cell line is selected based on its ability to self-renew. Preferably, the method selects against somatic cells based on their inability to self-renew. Preferably, the progenitor cell line is derived or established in the absence of co-culture, preferably in the absence of feeder cells, which preferably selects against embryonic stem cells. Optionally, the method comprises (d) deriving a differentiated cell from the progenitor cell line.01-20-2011
20110012090SILICON-GERMANIUM NANOWIRE STRUCTURE AND A METHOD OF FORMING THE SAME - A silicon-germanium nanowire structure arranged on a support substrate is disclosed, The silicon-germanium nanowire structure includes at least one germanium-containing supporting portion arranged on the support substrate, at least one germanium-containing nanowire disposed above the support substrate and arranged adjacent the at least one germanium-containing supporting portion, wherein germanium concentration of the at least one germanium-containing nanowire is higher than the at least one germanium-containing supporting portion. A transistor comprising the silicon-germanium nanowire structure arranged on a support substrate is also provided. A method of forming a silicon-germanium nanowire structure arranged on a support substrate and a method of forming a transistor comprising forming the silicon-germanium nanowire structure arranged on a support substrate are also disclosed.01-20-2011
20110008298METHOD OF DERIVING PROGENITOR CELL LINE - We disclose a method comprising: (a) providing an embryonic stem (ES) cell; and (b) establishing a progenitor cell line from the embryonic stem cell; in which the progenitor cell line is selected based on its ability to self-renew. Preferably, the method selects against somatic cells based on their inability to self-renew. Preferably, the progenitor cell line is derived or established in the absence of co-culture, preferably in the absence of feeder cells, which preferably selects against embryonic stem cells. Optionally, the method comprises (d) deriving a differentiated cell from the progenitor cell line.01-13-2011
20110007864METHOD AND APPARATUS FOR REORIENTATED RESCONSTRUCTION OF COMPUTED TOMOGRAPHY IMAGES OF PLANAR OBJECTS - A system and method for micro computed tomography (CT) reconstruction of position scan data of planar objects, such as stacked integrated circuit chips and/or PCB, that automatically determines object orientation is disclosed for a preferred orientation of the reconstructed images. The object orientation of the sinogram of the scanning data is determined such that the reconstruction may be performed with any starting position. Additionally, planar object scan reconstructions with either a higher resolution in the thickness dimension without increasing the total computation resource or a faster processing speed under a given resolution in the thickness dimension may be achieved. The tilting angle with respect to the rotation axis may also be determined to perform a image rotation after a multi-slice reconstruction or cone-beam reconstruction.01-13-2011
20100331550THIENOTHIOPHENE DERIVATIVES - An organic compound represented by the following general formula (I) and characterised by the conjugation of thieno[3,2-b]thiophene, thiophene and phenylene units in the conjugated compound.12-30-2010
20100323027MESENCHYMAL STEM CELL CONDITIONED MEDIUM - We disclose a method of preparing a conditioned cell culture medium, the method comprising the steps of: (a) culturing a mesenchymal stem cell (MSC), a descendent thereof or a cell line derived therefrom in a cell culture medium; and (b) optionally isolating the cell culture medium; in which the mesenchymal stem cell (MSC) is obtained by propagating a cell obtained by dispersing a embryonic stem (ES) cell colony, or a descendent thereof, in the absence of co-culture in a serum free medium comprising FGF2.12-23-2010
20100322496METHOD AND SYSTEM FOR ANATOMY STRUCTURE SEGMENTATION AND MODELING IN AN IMAGE - A method is proposed for segmenting one or more ventricles in a three-dimensional brain scan image (e.g. MR or CT). The image is registered against a brain model, which ventricle models of each of the one or more ventricles. Respective regions of interest are defined based on the ventricle models. Object regions are first obtained by applying region growing procedure in the regions of interest, and then trimmed based on anatomical knowledge. A 3D surface model of one or more objects is constructed within a 3D space from the segmented structure. A 3D surface is edited and refined by a user selecting amendment points in the 3D space which are indicative of missing detail features. A region of the 3D surface near the selected points is then warped towards the amendment points smoothly, and the modified patch is combined with the rest of the 3D surface yields the accurate anatomy structure model.12-23-2010
20100315145 APPARATUS FOR GENERATING A PLURALITY OF SIGNALS - An apparatus for generating a plurality of signals is provided. The apparatus provided includes a first signal generation unit, including an input receiving a reference signal, and a plurality of outputs providing a first plurality of output signals being generated based on the reference signal, wherein any two of the output signals have a different phase. The apparatus provided further includes a second signal generation unit, including at least two inputs receiving at least two signals selected from the first plurality of output signals generated by the first signal generation unit, and a plurality of outputs providing a second plurality of output signals generated by interpolating the respective phases of the received at least two signals selected from the first plurality of output signals. The apparatus provided further includes a selection unit, including a first plurality of inputs receiving the first plurality of output signals generated by the first signal generation unit, a second plurality of inputs receiving the second plurality of output signals generated by the second signal generation unit, and a plurality of outputs providing the plurality of signals wherein each of the signals is selected from the first plurality of output signals generated by the first signal generation unit and the second plurality of output signals generated by the second signal generation unit, wherein any two signals of the plurality of signals have a different phase.12-16-2010
20100314752FORMING AN ETCHED PLANARISED PHOTONIC CRYSTAL STRUCTURE - A method of forming a photonic crystal (PhC) structure and a PhC structure formed by such method. The method comprises forming holes in a Si-based host layer; filling the holes with a high-density plasma (HDP) deposited Si-based oxide and such that a surface of the Si-based host layer is directly covered with the Si-based oxide; performing at least a selective wet etching step for etching the Si-based oxide such that a surface of the resulting PhC structure is planarized.12-16-2010
20100314041METHOD OF MAKING A MULTILAYER SUBSTRATE WITH EMBEDDED METALLIZATION - A method of making a substrate includes providing an upper insulative layer and a lower insulative layer, wherein the upper insulative layer includes an inlet opening, the lower insulative layer includes a channel, and the inlet opening is in fluid communication with the channel, flowing a non-solidified material through the inlet opening into the channel, and then solidifying the non-solidified material by applying energy to the non-solidified material, thereby forming embedded metallization in the channel. The substrate can be a microfluidic device, an electrical interconnect or other electronic devices.12-16-2010
20100309560Method for Forming Variable Focus Liquid Lenses in a Tubular Housing - The present invention provides a variable focus fluid lens wherein the focal length is controllable by changing the contact angle of a fluid meniscus. A liquid (12-09-2010
20100300978DEVICE, SYSTEM AND METHOD FOR WASHING AND ISOLATING MAGNETIC PARTICLES IN A CONTINOUS FLUID FLOW - A device for washing and isolating magnetic particles from a continuous fluid flow in at least one fluidic channel having an inlet at one end and an outlet at another end, said device comprising at least one magnetic source carrier arranged proximate to the at least one fluidic channel. The at least one magnetic source carrier is moveable between a first position and a second position. The at least one magnetic source carrier comprises at least one first magnetic source, wherein a movement of the at least one magnetic source carrier to the first position places the at least one first magnetic source at a first spatial location along the at least one fluidic channel such that said at least one first magnetic source generates a maxima magnetic field at said first spatial location that attracts the magnetic particles from the continuous fluid flow and assembles said magnetic particles at said first spatial location. A movement of the at least one magnetic source carrier to the second position places the at least one first magnetic source distal from the first spatial location such that said magnetic field at said first spatial location is at a minima and the magnetic particles disperse from said first spatial location.12-02-2010
20100299136 Dialogue System and a Method for Executing a Fully Mixed Initiative Dialogue (FMID) Interaction Between a Human and a Machine - A method for executing a fully mixed initiative dialogue (FMID) interaction between a human and a machine, a dialogue system for a FMID interaction between a human and a machine and a computer readable data storage medium having stored thereon computer code for instructing a computer processor to execute a method for executing a FMID interaction between a human and a machine are provided. The method includes retrieving a predefined grammar setting out parameters for the interaction; receiving a voice input; analysing the grammar to dynamically derive one or more semantic combinations based on the parameters; obtaining semantic content by performing voice recognition on the voice input; and assigning the semantic content as fulfilling the one or more semantic combinations.11-25-2010
20100298504AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME - Disclosed are an amphiphilic polymer, its synthesis and uses thereof. The polymer has a hydrocarbon backbone with —COOH side groups. It further has first aliphatic moieties with a main chain of about 3 to about 20 carbon atoms and 0 to about 3 heteroatoms, and second aliphatic moieties that have a main chain of about 3 to about 80 carbon atoms and about 2 to about 40 heteroatoms. The second aliphatic moieties have a copolymerisable group. In the synthesis a maleic anhydride polymer of formula (I) where n is an integer from about 10 to about 10000 and R1 is H or methyl, is reacted with a monofunctional compound with an alkyl chain of about 3 to about 20 carbon atoms and 0 to about 2 heteroatoms, and with an at least bifunctional compound with an alkyl chain of about 3 to about 80 carbon atoms and 0 to about 40 heteroatoms. The functional group of the monofunctional compound and one functional group of the at least bifunctional compound can form a linkage with an anhydride. Another functional group of the at least bifunctional compound, which is not allowed to react with the maleic anhydride polymer, is copolymerisable.11-25-2010
20100295750ANTENNA FOR DIVERSITY APPLICATIONS - An antenna for ultra-wideband applications is disclosed. The antenna has a first radiating element shaped for defining a first notch, the first radiating element having a first feeding structure. The antenna further has a second radiating element operatively couplable to the first radiating element and shaped for defining a second notch. The second radiating element having a second feeding structure, the first and second feeding structures being substantially orthogonal to each other and the first and second radiating elements having an inter-displacement. More specifically, the first radiating element and the first feeding structure is substantially symmetrical to the second radiating element and the second feeding structure respectively about a line of symmetry passing through the inter-displacement between the first and second radiating elements for achieving orthogonal polarization and radiating pattern diversity between the first and second radiating elements.11-25-2010
20100292298METHOD AND REAGENTS FOR TREATING HEPATIC FIBROSIS AND INFLAMMATION - The invention relates to methods for identifying an anti-fibrotic or anti-inflammatory agent comprising determining cathepsin S expression in activated hepatic stellate cells which have been exposed to a test compound and comparing expression to non-exposed hepatic stellate cells. The invention also relates to methods for treating a disorder characterised or caused by hepatic fibrosis or inflammation, comprising administering a cathepsin S inhibitor to a subject.11-18-2010
20100291723METHOD OF MANUFACTURING AN ORGANIC ELECTRONIC OR OPTOELECTRONIC DEVICE - A method of manufacturing an organic electronic or optoelectronic device, the method comprising the steps of: (a) providing a substrate having a plurality of banks formed thereon with alternating well formations formed therebetween, the surface of said banks having imprint formations formed thereon of a dimension conferring a selected wetting property to the surface of said banks that is different from the surface of said wells; and (b) depositing an organic solution into said well formations, wherein the wetting property of said banks causes any organic solution deposited thereon to be at least partially repelled.11-18-2010
20100288689MICROFLUIDIC FILTRATION UNIT, DEVICE AND METHODS THEREOF - A microfluidic filtration unit for trapping particles of a predetermined nominal size present in a fluid is provided. The unit comprises a fluid chamber connected to an inlet for introducing the fluid to be filtered and an outlet for discharging filtered fluid, a filtration barrier arranged within the fluid chamber, said filtration barrier comprising a plurality of pillars arranged substantially perpendicular to the path of fluid flow when fluid is introduced into the fluid chamber, said pillars being aligned to form at least one row extending across said path of fluid flow, wherein each of said at least one row of pillars in the filtration barrier comprises at least one fine filtration section comprising a group of pillars that are spaced apart to prevent particles to be filtered from the fluid from moving between adjacent pillars, and at least one coarse filtration section comprising a group of pillars that are spaced apart to permit the movement of particles between adjacent pillars.11-18-2010
20100288382FLUID CARTRIDGE, PUMP AND FLUID VALVE ARRANGEMENT - A fluid cartridge, comprising a channel layer within which at least one circumferentially sealed fluid channel is formed, the channel layer comprising a substrate and an elastic layer fixedly arranged on the substrate, wherein the substrate has a rigidity being greater than that of the elastic layer, and wherein the at least one fluid channel is defined on at least one side thereof by the elastic layer.11-18-2010
20100285948Catalyst Preparation and Methods of Using Such Catalysts - A process for the pre-treatment of Mo/ZSM-5 and Mo/MCM-22 catalysts is provided, which process comprises heating the catalyst at 500° C. in the presence of propane. The treated catalyst, when used in the non-oxidative dehydrogenation of methane demonstrates improved benzene yield and catalyst stability as compared to catalysts pre-treated with He, methane or H11-11-2010
20100285601METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE - The method is performed by means of a pair of electrodes that are arranged at a distance and within a sensing zone. A nucleic acid capture molecule with an uncharged backbone and a nucleotide sequence that is at least partially complementary to at least a portion of a strand of the target nucleic acid molecule, is immobilised on an immobilisation unit. The immobilisation unit, which is arranged within the sensing zone, is contacted with a solution suspected to comprise the target nucleic acid molecule, which hybridizes to the nucleic acid capture molecule. An activation agent is added, which has an electrostatic net charge complementary to the net charge of the target nucleic acid molecule. It associates to the complex of nucleic acid capture molecule and target nucleic acid molecule. Added is a water soluble polymer with at least one polymer strand and with an electrostatic net charge that is complementary to the net charge of the activation agent. Thus the polymer associates to the activation agent. A metal salt is added, which can act as an oxidant and the metal ions of which have an electrostatic net charge complementary to the net charge of the polymer. The metal ions associate to the polymer. Upon adding a reducing agent, the latter reduces the metal ions, forming a metal wire. The presence of the analyte molecule is determined based on an electrical characteristic of a region in the sensing zone that is affected by the metal wire.11-11-2010
20100285475FUSED GENES - There is provided at least one isolated fused gene comprising at least one first gene and/or fragment thereof fused to at least one second gene and/or fragment thereof, wherein at least the first and/or the second gene, independently, is selected from the group consisting of: RCC2, CENPF, ARFGEF2, SULF2, MTAP, ATXN7, BCAS3, RPS6KB1, TMEM49, EAP30, a gene having the nucleotide sequence SEQ ID NO:1, and a gene having the nucleic acid SEQ ID NO:2, or a fragment thereof. There is also provided a diagnostic method and/or a kit for detecting the susceptibility, prognosis, and/or to tumour in a subject.11-11-2010
20100276310METHOD OF COATING A PARTICLE - Disclosed is a method of coating a particle, the method comprising contacting (i) a particle, wherein the surface of the particle comprises functional groups suitable to undergo a coupling reaction with at least a hydroxyl group, a halogen group or an alkoxy group, with (ii) molecules of formula (Ia) and/or (Ib): (Ia) or (Ib) wherein A is a metal or a metalloid, R11-04-2010
20100272737Novel Peptides and Protein and Uses Thereof - The present invention relates to a novel gene encoding a protein termed voltage gated calcium channels β subunit anchoring regulator protein (VDCC BARP) or a peptide fragments thereof. The present invention also relates to the use of VDCC BARP in Modulation of voltage gated calcium channels via altering the concentration of VDCC BARP or a peptide fragments thereof.10-28-2010
20100261251MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE - Two novel microorganisms, 10-14-2010
20100261165Methods, Compositions and Kits for Use in Prognosis, Characterization and Treatment of Cancer - The present invention provides methods, compositions and kits for the prognosis, characterization and treatment of cancers. The methods, compositions and kits of the invention comprise a set of markers whose expression is correlated with estrogen receptor beta function. Therefore, the methods, compositions and kits of the invention find particular use in endocrine-related cancers such as breast cancers.10-14-2010
20100253170LOW PROFILE SPINDLE MOTOR - A low profile spindle motor for supporting and rotating media disk or disks of a hard disk drive includes a plurality of stator teeth, a winding layer which may be formed by printed circuit board or the like, and a rotor. The plurality of stator teeth are disposed in an annular region surrounding an axis of rotation of the motor, and have projected ends for increasing the tooth area facing a magnet ring of the rotor. The winding layer has a plurality of windings disposed surrounding the axis of rotation. Each winding is coupled to one of the plurality of stator teeth. The magnet ring is positioned radially spaced apart and coplanar with the annular region. The magnet ring has magnetic poles annularly distributed to generate magnetic fluxes along radial direction. Spindle motor formed according to the invention has a low profile, improved performance and manufacturability.10-07-2010
20100249443TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES - The present invention relates to titanium catalysts for asymmetric synthesis reactions produced by bringing a reaction mixture obtained by contacting water and a titanium alkoxide into contact with an optically active ligand represented by the general formula (a), wherein R1, R2, R3, and R4 are independently a hydrogen atom, an alkyl group, or the like, and A* represents a group with two or more carbon atoms having an asymmetric carbon atom or axial asymmetry. The invention further relates to a process for asymmetric cyanation of imines, wherein the process comprises reacting an imine with a cyanating agent in the presence of the titanium catalyst.09-30-2010
20100227437SEMICONDUCTOR DEVICES GROWN IN SPHERICAL CAVITY ARRAYS AND ITS PREPARATION METHOD - A method for fabricating an array of semiconductor devices comprising the steps of providing a non-metallic substrate, placing a layer of spheres on said substrate, reducing diameter of the spheres, encapsulating the spheres in a matrix of rigid material, finishing an upper surface of said matrix to expose a portion of said spheres, removing the spheres to form an array of cavities within said matrix, and forming features in said cavities in contact with said substrate so as to form the device.09-09-2010
20100220815Method for Processing a Data Signal, Data Processing Unit and Computer Program Conduct - A method for processing a data signal received via a communication channel is described, comprising determining a first matrix comprising components describing characteristics of the communication channel and inverting the first matrix by sub-dividing the first matrix into at least four sub matrices, inverting a first sub matrix of the four sub matrices generating a second matrix by multiplying a second sub matrix of the four sub matrices with the inverted first matrix and a third sub matrix of the four sub matrices, determining the difference matrix between the second matrix and a fourth sub matrix of the four sub matrices inverting the difference matrix and calculating the inverted matrix based on the inverted difference matrix. The data signal is processed using the inverted first matrix.09-02-2010
20100219496WAFER ARRANGEMENT AND A METHOD FOR MANUFACTURING THE WAFER ARRANGEMENT - The wafer arrangement (09-02-2010
20100216413LEAKAGE SUPPRESSING CIRCUIT - A leakage suppressing circuit for a communication device is provided. The leakage suppressing circuit comprises a signal transforming unit having an input for receiving an input signal, a first output and a second output, the signal transforming unit being configured such that the phase of an output signal at the first output is at least substantially the same as or at least substantially opposite to the phase of an output signal at the second output, and the power of the output signal at the first output is at least substantially equal to the power of the output signal at the second output, a first signal directing unit, a second signal directing unit, and a combining unit.08-26-2010
20100208049IMAGING CHAMBER WITH WINDOW AND MICRO-NEEDLE PLATFORM MAGNETICALLY BIASED TOWARD EACH OTHER - A device for imaging a tissue culture comprises a chamber for housing a tissue to be cultured and imaged. The chamber comprises a transparent window. The device also includes a platform facing the window. Micro-needles are mounted on the platform and are connected for fluid communication with a fluid source. The platform and the window are magnetically biased toward each other to press the micro-needles into a tissue sandwiched between the window and platform for injecting a fluid into the tissue. One or more spacers are placed between the platform and the window for preventing over-compression of the tissue by the platform and the window. During use, a fluid is supplied to the tissue through the needles from the fluid source and the tissue is imaged through the window of the chamber.08-19-2010
20100202671METHOD AND DEVICE FOR DETERMINING A SIMILARITY VALUE BETWEEN MINUTIAE TEMPLATES - Embodiment of the invention provide a method and a device for determining a similarity value between a first template and a second template. A first cluster characteristic for each first cluster of a plurality of first clusters is determined, wherein each first cluster includes a plurality of first minutiae comprised in the first minutiae template. A second cluster characteristic for each second cluster of a plurality of second clusters is determined, wherein each second cluster includes a plurality of second minutiae comprised in the second minutiae template. The similarity value between the first minutiae template and the second minutiae template is determined based on the first cluster characteristics and the second cluster characteristics.08-12-2010
20100198760APPARATUS AND METHODS FOR MUSIC SIGNAL ANALYSIS - An apparatus for modelling layers in a music signal comprises a rhythm modelling module configured to model rhythm features of the music signal; a harmony modelling module configured to model harmony features of the music signal; and a music region modelling module configured to model music region features from the music signal.08-05-2010
20100197920N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS - The present invention generally relates to materials and methods for catalytic reactions, including transition metal-catalyzed cross-coupling reactions. The materials may be stable metal complexes that do not require special handling or processing conditions. In some cases, materials of the invention advantageously may be synthesize in one synthetic step without the need for isolation of intermediate compounds. Also, materials of the invention may be synthesized from inexpensive and readily available starting materials, under relatively mild reaction conditions that do not require the exclusion of air, water, and the like. In some embodiments, the material is a N-heterocyclic carbene metallacycle complex. Such materials and methods may be useful in the production of fine chemicals, advanced materials and specialty polymers.08-05-2010
20100194409METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE - The invention provides a method of electrically detecting a biological analyte molecule by means of a pair of electrodes. The electrodes are arranged at a distance from one another within a sensing zone. A capture molecule, which has an affinity to the analyte molecule and which is capable of forming a complex with the analyte molecule, is immobilised on an immobilisation unit. The immobilisation unit is contacted with a solution suspected to comprise the analyte molecule. The analyte molecule is allowed to form a complex with the capture molecule. The invention also provides a probe defined by a nanoparticulate tag that comprises or consists of electrically conducting matter that is capable of chemically interacting with the analyte molecule. In the method of the invention the electrically conducting nanoparticulate tag is added. Thereby the electrically conducting nanoparticulate tag is allowed to associate to the complex formed between the capture molecule and the analyte molecule. The presence of the analyte molecule is determined based on an electrical characteristic, influenced by the electrically conducting nanoparticulate tag, of a region in the sensing zone.08-05-2010
20100193993METHOD OF MAKING A SECONDARY IMPRINT ON AN IMPRINTED POLYMER - There is disclosed a method of making an imprint on a polymer structure comprising the step of pressing a mold having a defined surface pattern against the surface of a primary imprint of a polymer structure to form a secondary imprint thereon.08-05-2010
20100193781MICROMECHANICAL STRUCTURE AND A METHOD OF FABRICATING A MICROMECHANICAL STRUCTURE - A micromechanical structure and a method of fabricating a micromechanical structure are provided. The micromechanical structure comprises a silicon (Si) based substrate; a micromechanical element formed directly on the substrate; and an undercut formed underneath a released portion of the micromechanical element; wherein the undercut is in the form of a recess formed in the Si based substrate.08-05-2010
20100185699SYSTEM AND METHOD FOR REPRESENTING N-LINKED GLYCAN STRUCTURES - A fixed-length alpha-numeric code for representing N-linked glycan structures commonly found in secreted glycoproteins from mammalian cell cultures. The code employs a pre-assigned alpha-numeric index to represent the monosaccharides attached in different branches to the core glycan structure. The present branch-centric representation allows visualization of the structure while the numerical nature of the code makes it machine readable. A difference operator can be defined to quantitatively differentiate between glycan structures for further analysis. The code can be incorporated in a retrievable format into an information management system. A method is also provided for representing the structure of at least a portion of an oligosaccharide, using the fixed-length alpha-numeric code.07-22-2010
20100185000TITANIUM COMPOUND AND PROCESS FOR ASYMMETRIC CYANATION OF IMINES - The present invention relates to titanium catalysts for asymmetric synthesis reactions produced by bringing a reaction mixture obtained by contacting water and a titanium alkoxide into contact with an optically active ligand represented by the general formula (a), wherein R07-22-2010
20100182203BROADBAND ANTENNA FOR WIRELESS COMMUNICATIONS - An antenna formable on a ground plane for wireless communications is disclosed. The antenna has a first structure spatially displaced from a ground plane. The antenna also has a second structure coupled to the first structure and extending away from the ground plane. The antenna further has a third structure configured for disposing at least a portion of the first structure between the third structure and the ground plane, the third structure being grounded to the ground plane and being spatially displaced from the second structure, the second structure and the third structure being inter-configured for electromagnetic coupling therebetween for forming a magnetic loop. More specifically, electromagnetic field generated by the first structure and the second structure electromagnetically couples the third structure for inducing generation of broadband electromagnetic waves from the first, second and third structures.07-22-2010
20100179343METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE - The present invention relates to a method of producing an optically active cyanohydrin derivative, which comprises reacting an aldehyde or an asymmetrical ketone with a cyanating agent in the presence of a Lewis base and a titanium compound produced from a partial hydrolysate of titanium tetraalkoxide and an optically active ligand represented by formula (II) or a titanium oxoalkoxide compound represented by formula (I) [Ti07-15-2010
20100172553LOCALIZATION OF BRAIN LANDMARKS SUCH AS THE ANTERIOR AND POSTERIOR COMMISSURES BASED ON GEOMETRICAL FITTING - A method of estimating the location of the anterior and posterior commissures in a brain scan image is proposed. Firstly, a geometrical object is constructed using points on a brain scan image of an individual which are on the surface of the brain, such as an ellipse fitting the cerebral surface of a sagittal image of the mid-sagittal plane, or an adjacent sagittal plane. The locations on the MSP of the AC and PC landmarks (and optionally other landmarks) are estimated using the five parameters which define the ellipse, plus numerical values obtained in advance from statistical analysis of other individuals.07-08-2010
20100170086DEVICE, UNIT, SYSTEM AND METHOD FOR THE MAGNETICALLY-ASSISTED ASSEMBLING OF CHIP-SCALE, AND NANO AND MICRO-SCALE COMPONENTS ONTO A SUBSTRATE - A magnetically-assisted chip assembly unit for assembling at least one chip having a mounting surface and an attachment surface, wherein the attachment surface supports a magnetisable layer thereon and opposes said mounting surface, onto a substrate that has a corresponding chip mounting surface. The unit comprises a template wafer having at least one recess adapted to accommodate therein said chip; and a master wafer having at least one magnetisable element; wherein the template wafer is mounted on the master wafer and said magnetisable element is located at least proximate to the at least one recess such that the magnetisable element is capable of manipulating the chip into the recess, via its magnetisable layer when the magnetisable element is magnetized and generates a magnetic field. Once in the recess, the attachment surface of the chip faces at least a portion of the recess and the mounting surface of the chip faces an opening of the recess.07-08-2010
20100165913METHODS OF TRANSMITTING AND RECEIVING DATA - A method of transmitting data from a first communication device to a second communication device, comprising receiving a first signal on a first frequency channel from the second communication device, generating data, wherein the data comprises a reception status indicating whether there is interference on the first frequency channel due to a second signal transmitted by a third communication device, transmitting a third signal on a second frequency channel to the second communication device, wherein the transmission is carried out for a predetermined duration, receiving a fourth signal on the second frequency channel from the second communication device; and transmitting the data generated on the second frequency channel to the second communication device.07-01-2010
20100159508THERMALLY RESPONSIVE MICELLES - The invention provides an amphiphilic copolymer comprising monomer units derived from a first monomer and monomer units derived from a second monomer. The copolymer has at least one hydrophobic endgroup. The first monomer is such that the copolymer is thermally responsive and the second monomer comprises a carboxylic acid or carboxylate group.06-24-2010
20100150274Method and System for Determining a Signal Vector - A method for determining a signal vector comprising a plurality of components from a received signal vector is provided comprising performing a QR decomposition of a channel matrix characterizing the communication channel via which the signal vector was received and being expanded by variance information about the noise on the communication channel carrying out a plurality of determination steps using the QR decomposition of the expanded channel matrix, wherein in each step a set of possible sub-vectors of the signal vector is determined and wherein in each step, the number of possible sub-vectors in the set is lower than a predefined maximum number, and selecting one vector of the set of possible sub-vectors determined in the last step of the plurality of determination steps as the signal vector.06-17-2010
20100145214 SYSTEM AND METHOD FOR PROCESSING BRAIN SIGNALS IN A BCI SYSTEM - A system and method for processing brain signals in a BCI system. The method of processing brain signals in a BCI system includes the steps of processing the brain signals for control state detection to determine if a subject intends to use the BCI system; and processing the brain signals for command recognition if the control state detection method determines that the subject intends to use the BCI system.06-10-2010
20100136649Encapsulation of Cells in Biologic Compatible Scaffolds by Coacervation of Charged Polymers - This invention relates to a method for the encapsulation of cells in biologic compatible three dimensional scaffolds and the use of such cells encapsulated in a scaffold. The cells are embedded in a charged polymer that is complex coacervating with an oppositely charged polymer within biologic compatible scaffolds. The polymer complex embedding the cells is forming an ultra thin membrane on the surface of the three dimensional scaffold.06-03-2010
20100133117METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID - The invention provides methods and kits for the electrochemical detection and/or quantification of a target nucleic acid molecule by means of a detection electrode. In one method there is immobilized on the detection electrode a peptide nucleic acid (PNA) capture molecule, which has a nucleotide sequence that is at least partially complementary to at least a portion of the target nucleic acid molecule. The electrode is contacted with a solution expected to include the target nucleic acid molecule and the target nucleic acid molecule allowed to hybridize to the PNA, thereby allowing the formation of a complex between the PNA capture molecule and the target nucleic acid molecule. A polymerisable positively chargeable precursor is added, which associates to the complex formed between the PNA capture molecule and the target nucleic acid molecule. A suitable reactant molecule is added, initiating the polymerisation of the polymerisable positively chargeable precursor and the formation of an electroconductive polymer. An electrochemical measurement at the detection electrode is performed. In another method a nucleic acid capture molecule is immobilized on the electrode. In this method a polymerisable positively chargeable precursor, a suitable substrate molecule, and an enzyme attached to a detection probe nucleic acid molecule are used. The detection probe nucleic acid molecule is at least partially complementary to at least a portion of the target nucleic acid molecule. The detection probe hybridizes to a portion of the target nucleic acid that is different from the portion to which the capture nucleic acid molecule hybridises.06-03-2010
20100129608Modification of Surface Wetting Properties of a Substrate - A method of modifying the wetting properties of the surface of a substrate, the method comprising the step of applying a first mold having an imprint forming surface to said substrate to form a first imprint thereon, said imprint forming surface being chosen to modify the wetting properties of the substrate surface.05-27-2010
20100128272METHOD FOR DETECTING SURFACE PLASMON RESONANCE - There is disclosed a method and system for detecting a surface plasmon resonance associated with a fluid sample. The method includes the step of providing a piezoelectric substrate having at least two electrodes thereon, wherein at least one of said electrodes is coupled to a fluid sample. A light beam is transmitted toward the fluid sample to induce a oscillation frequency in the piezoelectric substrate. The oscillation frequency from said electrodes is then measured during transmittance of the light to detect the surface plasmon resonance associated with the fluid sample.05-27-2010
20100116682ELECTROCHEMICAL SENSOR WITH INTERDIGITATED MICROELECTRODES AND CONDUCTED POLYMER - The present invention generally relates to electronic devices and methods. In some cases, the invention provides a sensor device comprising a pair of interdigitated microelectrodes (05-13-2010
20100113832PALLADIUM CATALYSTS - The invention relates to a particulate substance comprising a particulate porous support coupled to a palladium species. The palladium species may comprise palladium nanoclusters. The particulate substance may be used as a catalyst for conducting a carbon-carbon coupling reaction or a reduction.05-06-2010
20100112943 RECEIVER ARRANGEMENT AND A TRANSMITTER ARRANGEMENT - A transmitter/receiver (a transceiver) having: a digital synthesizer signal generator (05-06-2010
20100108373DOUBLE-STACKED EBG STRUCTURE - In a double-stacked electromagnetic bandgap (EBG) structure, a first conductive plane and a second conductive plane are spaced apart in parallel. At least two EBG layers are embedded in parallel between the first conductive plane and the second conductive plane. The at least two EBG layers have different stopband characteristics. A plurality of vias connect the at least two EBG layers respectively to one of the first and second conductive planes. At least the vias connecting one of the EBG layers pass through via holes in cells of another EBG layer.05-06-2010
20100098248DEVICE AND METHOD OF GENERATING AND DISTRIBUTING ACCESS PERMISSION TO DIGITAL OBJECT - A system is provided, which includes at least one digital object owner client computing device, a trusted server computing device and at least one digital object consumer client computing device. Each of said at least one digital object owner client computing device is configured to transmit a created or amended access permission message to the trusted server computing device. The trusted server computing device is configured to generate, from the created or amended access permission message, at least one personalized access permission message, each of which is uniquely addressed to one of the at least one digital object consumer client computing device. The at least one digital object consumer client computing device is configured to enforce a download, from the trusted server computing device, of the at least one personalized access permission message uniquely addressed to the at least one digital object consumer client computing device.04-22-2010
20100093053Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.04-15-2010
20100090753CHARGE PUMP CIRCUIT - A charge pump circuit and a method of compensating current mismatch in a charge pump circuit. The charge pump circuit comprises a core charge pump circuit; a replica charge pump circuit for sensing a current mismatch in the core charge pump circuit and for converting the sensed current mismatch into a voltage signal V_ctrl; wherein V-ctrl is utilized for compensating the current mismatch in the core charge pump circuit.04-15-2010
20100085211SELF-POWERED IN-PIPE FLUID METER AND PIPING NETWORK COMPRISING A PLURALITY OF SUCH FLUID METERS - A self-powered in-pipe fluid meter to be mounted inside of a pipe carrying a fluid therein. The fluid meter comprises at least one sensing unit capable of measuring one or more parameters of the fluid inside of the pipe; a telemetric data transmission unit capable of telemetrically transmitting data including a measured fluid parameter to a host terminal and/or another fluid meter; and at least one fluid-driven power source unit capable of generating power from the fluid flow within the pipe and supplying power to the sensing unit and/or the transmission unit.04-08-2010
20100084032DISPENSER ARRANGEMENT FOR FLUIDIC DISPENSING CONTROL IN MICROFLUIDIC SYSTEM - A dispenser arrangement for fluidic dispensing control into a microfluidic component comprising an enclosed fluid holding area having a base portion and a top portion and a valve adapted to be movable between an open position and a closed position and positioned at least partially in the fluid holding area. The valve comprises an elongated hollow portion having a body and two ends adapted for fluid flow from the fluid holding area to the microfluidic component in the open position, a first opening on the body of the hollow portion positioned within the fluid holding area allowing fluid communication from the fluid holding area to the microfluidic component in the open position, a sealing portion connected to a first end of the hollow portion positioned within the fluid holding area adapted for sealing connection with the top portion of the fluid holding area in the closed position and a slant second opening at a second end of the hollow portion positioned outside of the fluid holding area. The slant second opening is adapted to pierce through a sealing layer covering the microfluidic component in the open position and to insert into a first substrate housing the microfluidic component in the closed position. A dispenser unit comprising a dispenser arrangement and an actuator, wherein the actuator is a piston is also disclosed.04-08-2010
20100080270RADIO FREQUENCY INDENTIFICATION TRANSCEIVER - A radio frequency identification transceiver is disclosed. The radio frequency identification transceiver includes: a transmitter path, including; a pulse shaper to tunably shape the pulse of a signal to be transmitted in different predefined frequency ranges; a modulator to modulate the shaped pulse to be transmitted into one of a plurality of predefined frequency ranges; a receiver path, including: a demodulator to demodulate a received signal from a plurality of predefined frequency ranges.04-01-2010
20100075915METHODS FOR CANCER THERAPY AND STEM CELL MODULATION - The present invention relates to a method of inducing apoptosis in a tumour cell as well as modulating pluripotency and/or self-renewing characteristics of a stem/progenitor cell. The method comprises administering to the respective cell a compound of general formula (I). In general formula A is C or N. R03-25-2010
20100068691TISSUE SYSTEM AND METHODS OF USE - Apparatus and methods of use of a tissue system for culture and perfusion. The apparatus comprises needles for injecting a fluid into the tissue.03-18-2010

Patent applications by Agency For Science, Technology and Research