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Agence Nationale de Recherches Sur le Sida Et Les Hepatitis Virales

Paris, FR

Agence Nationale de Recherches Sur le Sida Et Les Hepatitis Virales Patent applications
Patent application numberTitlePublished
20110182937Dendritic Cell Vaccines - Compositions and methods for the prophylaxis and treatment of human immunodeficiency virus (HIV) infections are disclosed herein. More specifically the present invention discloses describes an autologous dendritic cell (DC) vaccine product derived by culturing a patient's monocytes with granulocyte macrophage colony stimulating factor (GM-CSF) and interferon alpha 2b (IFN-α), loading the DC with a mixture of five lipopeptides of Gag, Nef and Pol HIV antigens, and, optionally activating the DC with lipopolysaccharide (LPS).07-28-2011