| ADVANCED NEUROMODULATION SYSTEMS, INC. Patent applications |
| Patent application number | Title | Published |
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| 20120089203 | ELECTRICAL CONNECTIONS FOR USE IN IMPLANTABLE MEDICAL DEVICES - There is disclosed various embodiments of an electrical connection for electrically connecting implantable medical devices together, such as an electrical connector for connecting an implantable pulse generator to a medical lead. In one embodiment, the electrical connection may include a body having a longitudinal opening defined therein for receiving an electrode of the medical lead and a spring coupled to the body and positioned within the opening, the spring having a curved surface for engaging the surface of the electrode. | 04-12-2012 |
| 20120078319 | STIMULATION DESIGN FOR NEUROMODULATION - The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds. | 03-29-2012 |
| 20120061358 | METHOD OF FABRICATING A STIMULATION LEAD FOR DELIVERING ELECTRICAL PULSES TO TISSUE OF A PATIENT - In one embodiment, a method of fabricating stimulation leads, the method comprises: providing a spool of polymer film; providing a plurality of payout carriers of wires; drawing the polymer film from the spool and the wires from the plurality of payout carriers over a rotating drum, wherein the drum comprises a plurality of grooves over an outer circumferential surface of the drum for directing the wires from the plurality of payout carriers, wherein a distance of each groove from an edge of the drum is varied about the circumference of the drum; bonding the wires to the polymer film while performing the drawing to form an intermediate assembly comprising the polymer film as a carrier with the bonded wires in a repeating pattern along a length of the intermediate assembly. | 03-15-2012 |
| 20120022611 | METHODS AND APPARATUS FOR EFFECTUATING A LASTING CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. The methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain). | 01-26-2012 |
| 20120010671 | NOTCHED ELECTRODE FOR ELECTROSTIMULATION LEAD - According to one embodiment, an electrode for use in electrostimulation is provided, where the electrode comprises a notch that operates to substantially eliminate gaseous material from being trapped about the electrode during a molding process of an electrostimulation lead. | 01-12-2012 |
| 20110319969 | ELECTRIC MODULATION OF SYMPATHETIC NERVOUS SYSTEM - A method is described for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure. | 12-29-2011 |
| 20110273225 | PULSE GENERATOR HAVING AN EFFICIENT FRACTIONAL VOLTAGE CONVERTER AND METHOD OF USE - Disclosed are systems and methods which provide voltage conversion in increments less than integer multiples of a power supply (e.g., battery) voltage. A representative embodiment provides power supply voltage multipliers in a binary ladder distribution to provide a desired number of output voltage steps using a relatively uncomplicated circuit design. By using different sources in various combinations and/or by “stacking” different sources in various ways, the voltage multiplier circuit may be used to provide desired voltages. In order to minimize the number of components used in a voltage converter of an embodiment, a capacitive voltage converter circuit uses one or more storage capacitors in place of pump capacitors in a voltage generation cycle. Also, certain embodiments do not operate to generate an output voltage until the time that voltage is needed. | 11-10-2011 |
| 20110243423 | SYSTEM AND METHOD FOR INSPECTING ELECTRICAL STIMULATION LEADS - In one embodiment, a method of inspecting a lead body comprising a plurality of wire conductors helically wound in groups separated by respective gaps, the system comprises: providing a lead body comprising a plurality of wire conductors, helically wound in groups separated by respective gaps, in transparent insulative material, in a channel of a fixture; providing a sensor module; scanning the sensor module along a substantial length of the lead body to obtain image, interferometric, or other data of the lead body; electronically processing the data to calculate respective distances from given turns within a group of the wire conductors from an other sheath of the lead body; determining whether the calculated respective distances correspond to expected values within defined tolerances; and generating an inspection report for the lead body based on the determining. | 10-06-2011 |
| 20110208265 | MULTI-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 08-25-2011 |
| 20110178568 | ELECTRIC MODULATION OF SYMPATHETIC NERVOUS SYSTEM - A method is described for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure. | 07-21-2011 |
| 20110167631 | METHOD FOR PRODUCING A MULTIELECTRODE LEAD - A wire wrapping device that includes a turntable assembly that is made up of a turntable and a driver adapted to rotate the turntable. Also, a set of payout carriers are mounted on the turntable, each payout carrier adapted to let out wire to be wrapped. A driver is adapted to turn each payout carrier relative to the turn table, the driver being user adjustable to turn each payout carrier by a selectable amount, per each complete rotation of the turntable. | 07-14-2011 |
| 20110098778 | STIMULATION SYSTEM AND METHOD TREATING A NEUROLOGICAL DISORDER - According to one aspect, a method of treating a patient by electrically stimulating a predetermined site to treat a neurological condition. The method includes implanting a lead into subcutaneous tissue of the C | 04-28-2011 |
| 20100298919 | WINGED ELECTRODE BODY FOR SPINAL CORD STIMULATION - An implantable stimulation system including epidural lead for spinal cord stimulation that includes a paddle having a curved proximal end and lateral winged tips and an array of electrodes coupled to conductors within a lead body. The conductors couple to a pulse generator or other stimulation device. The curved and winged paddle provides more complete electrical stimulation coverage to targeted human tissue by minimizing the potential gap between electrodes and targeted fibers. | 11-25-2010 |
| 20100269339 | METHOD OF FABRICATING STIMULATION LEAD BY FUSING CONNECTOR SEGMENT BETWEEN LEAD BODY AND ELECTRODE PORTION OF THE LEAD - In one embodiment, a process, for fabricating a medical lead comprises: providing a splicing tube having a plurality of angularly spaced longitudinal grooves; placing a first plurality of conductors within the plurality of angularly spaced grooves defined on an exterior surface of the splicing tube; placing a second plurality of conductors within the plurality of angularly spaced grooves and adjacent to the first plurality of conductors such that a portion of the distal ends overlap a portion of the proximal ends; positioning conductive filler material adjacent to the overlapped portions of the distal and proximal ends; electrically coupling the proximal ends of the first plurality of electrodes to respective proximal ends of the second plurality of electrodes; molding insulative material about at least the electrode assembly and the splicing tube; and fusing the splicing tube with the insulative material from the molding and the lead body. | 10-28-2010 |
| 20100269338 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a process, for fabricating a medical lead for stimulation of tissue of a patient, comprises: providing a plurality of wires; increasing an exterior surface area of each wire of the plurality of wires; arranging the plurality of wires angularly around a longitudinal axis; extruding polymer material of the plurality of wires; forming a lead body with a proximal end and a distal end after performing the extruding; and forming a plurality of terminals at a proximal end of the lead body; forming a plurality of segmented electrodes at a distal end of the lead body. | 10-28-2010 |
| 20100269337 | MEDICAL LEADS WITH SEGMENTED ELECTRODES AND METHODS OF FABRICATION THEREOF - In one embodiment, a process, for fabricating a medical lead for stimulation of tissue of a patient, comprises: forming a plurality of electrode assemblies wherein each electrode assembly of the plurality of electrode assemblies comprises a respective plurality of segmented electrodes angularly separated by ribs formed in one or more segments of thermoplastic tape; electrically coupling a conductor to each segmented electrode; molding polymer material around each segmented electrode of the plurality of segmented electrodes to interlock each segmented electrode with polymer material to form a distal end of the medical lead; and fusing the one or more segments of thermoplastic tape of each of the plurality of electrode assemblies with the polymer material. | 10-28-2010 |
| 20100262205 | STIMULATION DESIGN FOR NEUROMODULATION - The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds. | 10-14-2010 |
| 20100241189 | Nerve Stimulation For Treatment of Obesity, Metabolic Syndrome, and Type 2 Diabetes - A tissue modulation device, for treating at least one of obesity, metabolic syndrome, and Type 2 diabetes in a patient, is described. In some embodiments, the device includes a storage module having computer-readable instructions for delivering an electrical stimulation pattern to a splanchnic nerve of the patient. The stimulation pattern includes at least one on-time. The on-time includes at least one of a suprathreshold period and a subthreshold period. The splanchnic nerve is selected from the group consisting of the greater splanchnic nerve, the lesser splanchnic nerve, and the least splanchnic nerve. The pattern is effective to ameliorate at least one attendant condition of obesity, metabolic syndrome, and Type 2 diabetes in the patient. The attendant condition includes dyslipidemia, hypertension, hyperinsulinemia, hyperglycemia, and/or insulin resistance. | 09-23-2010 |
| 20100204749 | STIMULATION SYSTEM AND METHOD TREATING A NEUROLOGICAL DISORDER - According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area, or stimulating cervical nerve roots and/or stimulating cranial nerves and/or stimulating any area associated with the occipital area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition. | 08-12-2010 |
| 20100193065 | METHOD FOR PRODUCING A MULTIELECTRODE LEAD - A wire wrapping device that includes a turntable assembly that is made up of a turntable and a driver adapted to rotate the turntable. Also, a set of payout carriers are mounted on the turntable, each payout carrier adapted to let out wire to be wrapped. A driver is adapted to turn each payout carrier relative to the turn table, the driver being user adjustable to turn each payout carrier by a selectable amount, per each complete rotation of the turntable. | 08-05-2010 |
| 20100145428 | METHOD OF USING SPINAL CORD STIMULATION TO TREAT NEUROLOGICAL DISORDERS OR CONDITIONS - The present invention involves methods and systems for using electrical stimulation to treat neurological disorders. More particularly, the method comprises surgically implanting an electrical stimulation lead that is in communication with spinal nervous tissue associated with a first, second, or third cervical vertebral segment to result in spinal nervous tissue stimulation, thus treating a wide variety of neurological disorders. | 06-10-2010 |
| 20100145427 | METHODS AND APPARATUS FOR EFFECTUATING A LASTING CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The following disclosure describes several methods and apparatus for intracranial electrical stimulation to treat or otherwise effectuate a change in neural-functions of a patient. Certain embodiments of methods in accordance with the invention electrically stimulate the brain at a stimulation site where neuroplasticity is occurring or is expected to occur. The stimulation site may be different than the region in the brain where neural activity is typically present to perform the particular neural function according to the functional organization of the brain. In one embodiment in which neuroplasticity related to the neural-function occurs in the brain, the method can include identifying the location where such neuroplasticity is present or expected to occur. In an alternative embodiment in which neuroplasticity is not occurring in the brain, an alternative aspect is to induce neuroplasticity at a stimulation site where it is expected to occur. Several embodiments of these methods that are expected to produce a lasting effect on the intended neural activity at the stimulation site use electrical pulses that increase the resting membrane potential of neurons at the stimulation site to a subthreshold level. | 06-10-2010 |
| 20100141676 | SYSTEM FOR REGIONAL DATA ASSOCIATION AND PRESENTATION AND METHOD FOR THE SAME - A database methodology that concerns the mapping of any arbitrary object into a plurality of regions, enabling the assignment of multiple region-specific attributes thereto and facilitating the concurrent, graphical presentation of any assigned attributes. Attribute storage, manipulation, and presentation are driven by the individual regions and characteristics of the object. | 06-10-2010 |
| 20100131034 | SYSTEMS AND METHODS FOR AUTOMATICALLY OPTIMIZING STIMULUS PARAMETERS AND ELECTRODE CONFIGURATIONS FOR NEUROSTIMULATORS - Test procedures for determining a neural stimulation threshold of a patient. In one embodiment, the procedure includes applying a test stimulation signal to the patient and monitoring the patient for a response to the test stimulation signal. The procedure can further include determining a first neural stimulation threshold and calculating a second neural stimulation threshold. The first neural stimulation threshold corresponds to the lowest intensity test stimulation signal that evokes a patient response. The second neural stimulation threshold corresponds to a treatment stimulation signal directed toward affecting a neural activity within the patient. | 05-27-2010 |
| 20100131030 | METHODS AND APPARATUS FOR EFFECTUATING A CHANGE IN A NEURAL-FUNCTION OF A PATIENT - The present disclosure is directed generally to methods and apparatus for effectuating a change in a neural function of a patient. A method in accordance with a particular embodiment includes implanting an electrode at a cortical stimulation site selected to promote recovery of the affected neural-function, with the cortical stimulation site being at least proximate to the cortex. The method can further include estimating a threshold for the specific patient at which an electrical signal delivered via the implanted electrode directly triggers a neural reaction associated with the stimulation site in response to the delivered electrical signal, and electrically stimulating the cortical stimulation site by Passing an electrical current through the electrode. | 05-27-2010 |
| 20100114193 | METHOD OF TREATING DEPRESSION, MOOD DISORDERS AND ANXIETY DISORDERS USING NEUROMODULATION - The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety. | 05-06-2010 |
| 20100057160 | Stimulation of the amygdalohippocampal complex to treat neurological conditions - A system and/or method treating for a neurological disorder by brain region stimulation. The system and/or method comprises a probe and a device to provide stimulation. The probe has a stimulation portion implanted in communication with a predetermined brain region site. The stimulation portion of the probe may be implanted in contact with a predetermined brain region. | 03-04-2010 |
| 20100004637 | System and method for implantation of devices having unknown biocompatible materials - There is disclosed a system and method for allowing use within a body of devices having material not known for its biocompatibility with the body. In one embodiment, a magnetically controlled solenoid/valve is used where portions of the valve are directly in contact with compositions that are to be delivered to a target site. Advantage is taken of an existing solenoid/valve having chromium alloy parts by coating the portions of the valve that contact the deliverable composition with a known biocompatible material having good wear resistance. In one embodiment, titanium nitride (TiN) is used as the coating material. | 01-07-2010 |
| 20090292344 | METHODS AND SYSTEMS FOR INTRACRANIAL NEUROSTIMULATION AND/OR SENSING - Methods and systems for intracranial neurostimulation and/or sensing are disclosed. An intracranial signal transmission system in accordance with an embodiment of the invention includes a generally electrically insulating body having a head portion configured to be positioned at least proximate to an outer surface of a patient's skull, and a shaft portion configured to extend into an aperture in the patient's skull. The system can further include at least one electrical contact portion integrated with the support body. The at least one electrical contact portion can be positioned to transfer electrical signals to, from, or both to and from the patient's brain via an aperture in the patient's skull. | 11-26-2009 |
| 20090143845 | NOTCHED ELECTRODE FOR ELECTROSTIMULATION LEAD - According to one embodiment, an electrode for use in electrostimulation is provided, where the electrode comprises a notch that operates to substantially eliminate gaseous material from being trapped about the electrode during a molding process of an electrostimulation lead. | 06-04-2009 |
| 20090024187 | MULIT-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 01-22-2009 |
| 20080297527 | SYSTEM FOR REGIONAL DATA ASSOCIATION AND PRESENTATION AND METHOD FOR THE SAME - A database methodology that concerns the mapping of any arbitrary object into a plurality of regions, enabling the assignment of multiple region-specific attributes thereto and facilitating the concurrent, graphical presentation of any assigned attributes. Attribute storage, manipulation, and presentation are driven by the individual regions and characteristics of the object. | 12-04-2008 |
