| ADVANCED CARDIOVASCULAR SYSTEMS, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120079706 | Stent Crimping Methods - A process for crimping stents includes a multi-stage process producing a desired stent retention and crimped profile in a reduced amount of time. The process achieves results by utilizing particular combinations of heat and pressure during the crimping process, which was found to produce the desired results. | 04-05-2012 |
| 20120064098 | Intracoronary Device And Method Of Use Thereof - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 03-15-2012 |
| 20120029616 | Stent Support Devices - Various embodiments of methods and devices for coating stents are described herein. | 02-02-2012 |
| 20110293675 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS - An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided. | 12-01-2011 |
| 20110268607 | Reduced Temperature Sterilization of Stents - Methods and systems for reduced temperature radiation sterilization of stents are disclosed. | 11-03-2011 |
| 20110265426 | Reduced Temperature Sterilization of Stents - Methods and systems for reduced temperature radiation sterilization of stents are disclosed. | 11-03-2011 |
| 20110224778 | STENT PATTERN FOR POLYMERIC STENTS - A stent having a stent pattern including a plurality of cylindrical rings, each ring including a plurality of diamond-shaped cells having four curved elements defining apices of the diamond-shaped cells is disclosed herein. | 09-15-2011 |
| 20110212139 | HIGH-DENSITY LIPOPROTEIN COATED MEDICAL DEVICES - Method are disclosed for local and systemic administration HDL, recombinant HDL or HDLm for the prevention, treatment, or amelioration of a vascular disorder, disease or occlusion such as restenosis or vulnerable plaque. | 09-01-2011 |
| 20110211990 | Radiation Sterilization of Medical Devices - A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam. | 09-01-2011 |
| 20110207843 | Polymer-Bioceramic Composite Implantable Medical Devices - Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed. | 08-25-2011 |
| 20110202126 | Polymer-Bioceramic Composite Implantable Medical Device with Different Types of Bioceramic Particles - Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed. | 08-18-2011 |
| 20110200660 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY - A method of forming a coating on a medical device having a controlled morphology is described. A medical device having a controlled morphology is described. | 08-18-2011 |
| 20110200482 | Radiation Sterilization of Medical Devices - A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam. | 08-18-2011 |
| 20110196471 | Delivery of a Stent at an Elevated Temperature - Methods and systems of delivering a stent at an elevated temperature are disclosed herein. | 08-11-2011 |
| 20110190875 | Drug Delivery After Biodegradation Of The Stent Scaffolding - Disclosed herein is a stent comprising: a bioabsorbable polymeric scaffolding; and a coating comprising a bioabsorbable material on at least a portion of the scaffolding, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the coating. | 08-04-2011 |
| 20110153004 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY - A method of forming a coating on a medical device having a controlled morphology is described. A method of treating a disorder in a patient using the medical device is described. | 06-23-2011 |
| 20110152764 | BALLOON CATHETER HAVING IMPROVED BALLOON SEAL - The end cap is preferably formed of a relatively high durometer material with an inner surface on an outer surface of the shaft and on an outer surface of the balloon skirt section, and contacts a compression member on the balloon outer surface. The configuration prevents or inhibits failure at the balloon seals which otherwise results from the compression member moving or the balloon pulling off the shaft and out from under the compression member during inflation of the balloon. As a result, the balloon catheter of the invention has an improved consistent burst pressure and/or failure mode. | 06-23-2011 |
| 20110151104 | POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY - A method of forming a coating on a medical device having a controlled morphology is described. | 06-23-2011 |
| 20110144741 | Coating Construct With Enhanced Interfacial Compatibility - The present invention provides a method of forming a coating on a medical device having a topcoat and a basecoat and an improved compatibility between a topcoat and a basecoat on the medical device. | 06-16-2011 |
| 20110112627 | Stents with Enhanced Fracture Toughness - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 05-12-2011 |
| 20110098803 | Controlled Degradation Of Stents - Stents fabricated from hydrolytically degradable polymers with accelerated degradation rates and methods of fabricating stents with accelerated degradation rates are disclosed. | 04-28-2011 |
| 20110098740 | METHOD AND APPARATUS FOR CAPTURING OBJECTS BEYOND AN OPERATIVE SITE IN MEDICAL PROCEDURES | 04-28-2011 |
| 20110086162 | Concentration Gradient Profiles For Control of Agent Release Rates From Polymer Matrices - The present invention generally encompasses methods of coating which control of the release rate of agents from a polymeric matrix. This control over the release rate of agents provides for control over, inter alia, the therapeutic, prophylactic, diagnostic, and ameliorative effects that are realized by a patient in need of such treatment. In addition, the control of the release rate of agents also has an effect upon the mechanical integrity of the polymeric matrix, as well as a relationship to a subject's absorption rate of the absorbable polymers. | 04-14-2011 |
| 20110076386 | Stent Fixture and Method for Reducing Coating Defects - A stent fixture for supporting a stent during formation of a coating is provided. | 03-31-2011 |
| 20110073036 | Selectively Coating Luminal Surfaces of Stents - With abluminal side of a stent masked, the luminal side of the stent is selectively coated with a substance, such as an anti-coagulant, a platelet inhibitor and/or a pro-healing substance. The stent can be masked by inserting it into a rigid mandrel chamber or by compressing a masking sleeve onto the outer side of the stent. A spray nozzle inserted into the masked stent spray coats the substance onto the luminal side. The sprayed coating can be cured onto the stent such as by inserting an electrical-resistance heater bar into the stent. | 03-31-2011 |
| 20110070355 | POLYMERIC MARKER WITH HIGH RADIOPACITY FOR USE IN MEDICAL DEVICES - High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution and a wetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guidewire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion. | 03-24-2011 |
| 20110070283 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 03-24-2011 |
| 20110029008 | GUIDE WIRE WITH EMBOLIC FILTERING ATTACHMENT - A separate deliverable embolic protection device filter that attaches to a helical coil at a distal end of a conventional guide, for use in a blood vessel when an interventional procedure is being performed to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filter assembly with a proximal end and a distal end, and a guide wire connector attached to the distal end of the filter assembly. The guide wire connector is able to couple with the helical coil of the guide wire. A restraining sheath placed over the filter assembly in a coaxial arrangement maintains the filter assembly in a collapsed position and delivers the filter assembly separately to the helical coil of the guide wire, and then the guide wire connector is joined to the helical coil. Alternatively, the guide wire can include a rotatable coil section forming a portion of the distal tip coil on the guide wire which is adapted to be coupled to the filter assembly. This arrangement allows the filter assembly to be rotatably mounted onto the guide wire. | 02-03-2011 |
| 20110028072 | Surface Treatment of a Polymeric Stent - Methods of treating the polymeric surfaces of a stent with a fluid including a solvent for the surface polymer are disclosed. | 02-03-2011 |
| 20110027336 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 02-03-2011 |
| 20110027188 | Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers - An implantable medical device is disclosed having a plurality of smaller particles contained in a plurality of larger particles and configured to be released from the larger particles when the device is implanted in a patient. The smaller particles and the larger particles are made of bioabsorbable metal, glass or ceramic. A substance can be associated with the smaller particles. The larger particles can be embedded within at least a portion of the device. | 02-03-2011 |
| 20110015726 | Copolymer-Bioceramic Composite Implantable Medical Devices - Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed. The bioceramic comprises calcium sulfate. | 01-20-2011 |
| 20110009948 | Fiber Reinforced Composite Stents - Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed. | 01-13-2011 |
| 20110008529 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-13-2011 |
| 20110003068 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-06-2011 |
| 20110001271 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-06-2011 |
| 20100289191 | METHODS OF FABRICATING STENTS WITH ENHANCED FRACTURE TOUGHNESS - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 11-18-2010 |
| 20100276857 | COATING ABLUMINAL SURFACES OF STENTS AND OTHER IMPLANTABLE MEDICAL DEVICES - A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces. | 11-04-2010 |
| 20100269752 | COATING ABLUMINAL SURFACES OF STENTS AND OTHER IMPLANTABLE MEDICAL DEVICES - A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces. | 10-28-2010 |
| 20100269751 | COATING ABLUMINAL SURFACES OF STENTS AND OTHER IMPLANTABLE MEDICAL DEVICES - A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces. | 10-28-2010 |
| 20100266659 | IMPLANTABLE DEVICES FORMED ON NON-FOULING METHACRYLATE OR ACRYLATE POLYMERS - Implantable devices formed of or coated with a material that includes a polymer having a non-fouling acrylate or methacrylate polymer are provided. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 10-21-2010 |
| 20100222872 | Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers - Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed. | 09-02-2010 |
| 20100221409 | Stent Fixture Having Rounded Support Structures and Method for Use Thereof - A stent fixture for supporting a stent during the application of a coating substance is provided. | 09-02-2010 |
| 20100198343 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198342 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198341 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198340 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198339 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100183799 | Stent Coating Method And Apparatus - An apparatus includes a mandrel for supporting a stent during a composition deposition process. The mandrel includes an elongated body for insertion into a longitudinal bore of a stent. The body comprises carbide. | 07-22-2010 |
| 20100174355 | DELIVERY AND RECOVERY SHEATHS FOR MEDICAL DEVICES - A deployment control system provides controlled deployment of an embolic protection device which may include a guide wire, an expandable filter attached to the guide wire near its distal end, and a restraining sheath that maintains the expanded filter in a collapsed position. The deployment control system includes a torque control device which allows the physician to torque the guide wire into the patient's anatomy and a mechanism for preventing the guide wire from buckling as the restraining sheath is being retracted to deploy the expandable filter. A recovery control system for recovering the embolic protection device includes an inner catheter which extends within a lumen of an outer recovery sheath in a coaxial arrangement. A distal portion of the inner catheter extends beyond another recovery sheath during advancement of the recovery system into the vasculature. The recovery sheath can be advanced over the inner catheter to collapse the expandable filter. The proximal ends of the inner catheter and recovery sheath include handle portions having snap mechanisms which hold the components together as the recovery system is being advanced into the patient's vasculature. | 07-08-2010 |
| 20100174303 | INTRAVASCULAR STENT FOR TREATING VULNERABLE PLAQUE AND METHOD OF USE - An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque. | 07-08-2010 |
| 20100173065 | Methods For Immobilizing Anti-Thrombogenic Material Onto A Medical Device Or Into A Coating Thereon - The present invention is directed to a medical device having a polymerized base coat layer for the immobilization of an anti-thrombogenic material, such as heparin, thereon. The binding coat layer is comprised of various chemically functional groups which are stable and allow for the immobilization of the anti-thrombogenic material thereto. Methods for immobilizing the anti-thrombogenic material within the base coat layer posited on a surface of the medical device are also provided. | 07-08-2010 |
| 20100168843 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 07-01-2010 |
| 20100162950 | Stent Mandrel Fixture and Method for Selectively Coating Surfaces of a Stent - A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided. | 07-01-2010 |
| 20100152769 | LOCKING COMPONENT FOR AN EMBOLIC FILTER ASSEMBLY - A locking component for locking a medical device onto a guide wire. Such medical devices include, for example, an embolic filter assembly used to capture embolic material that may be created and released into a patient's vasculature during a stenting or angioplasty procedure. The embolic filter assembly tracks along the guide wire, and is delivered to a treatment site where it is locked in place and deployed. The locking component enables the filter assembly to lock onto any standard guide wire, and does not require a modified guide wire that has a specially-designed fitting or stop to accomplish the locking function. | 06-17-2010 |
| 20100140105 | HIGH STRENGTH MEMBER FOR INTRACORPOREAL USE - This invention is directed to an intracorporeal device formed of a high strength Co—Ni—Cr alloy and is particularly suitable for forming a composite product with a pseudoelastic member formed of NiTi alloy. Suitable intracorporeal products include guidewires and stents. The high strength alloy consists essentially of about 28 to about 65% cobalt, about 2 to about 40% nickel, about 5 to about 35% chromium, up to about 12% molybdenum, up to about 20% tungsten, up to about 20% iron and the balance inconsequential amounts of impurities and other alloying constituents, with a preferred alloy composition including about 30 to about 45% cobalt, about 25 to about 37% nickel, about 15 to about 25% chromium and about 5 to about 15% molybdenum. Intravascular devices such as guidewires, stents and the like can be formed of this high strength Co—Ni—Cr alloy. | 06-10-2010 |
| 20100126655 | BALLOON CATHETER HAVING IMPROVED BALLOON SEAL - The end cap is preferably formed of a relatively high durometer material with an inner surface on an outer surface of the shaft and on an outer surface of the balloon skirt section, and contacts a compression member on the balloon outer surface. The configuration prevents or inhibits failure at the balloon seals which otherwise results from the compression member moving or the balloon pulling off the shaft and out from under the compression member during inflation of the balloon. As a result, the balloon catheter of the invention has an improved consistent burst pressure and/or failure mode. | 05-27-2010 |
| 20100122768 | CATHETER SHAFT JUNCTION HAVING A POLYMERIC MULTILAYERED SLEEVE WITH A LOW PROCESSING TEMPERATURE OUTER LAYER - One aspect of the invention is directed to a balloon catheter with a multilayered polymeric sleeve at the rapid exchange intermediate section, having an outer layer formed of a polymer with a relatively low processing temperature (i.e., melting temperature for semi-crystalline polymers or glass transition temperature for amorphous polymers), and having an inner layer. | 05-20-2010 |
| 20100121374 | SHEATHLESS EMBOLIC PROTECTION SYSTEM - A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be compressed for insertion thereof through a patient's vasculature so as to cross the stenosis in a low profile, and to enable release of compression thereof for expansion and deployment of the device at a location distal to the interventional procedure site. | 05-13-2010 |
| 20100069721 | ROTATABLE FERRULES AND INTERFACES FOR USE WITH AN OPTICAL GUIDEWIRE - The invention is directed to devices and methods for passing optical radiation into and out of a body lumen. In particular, the invention is directed to a rotatable ferrule for use in an optical guidewire and methods for using a rotatable ferrule. The rotatable ferrule may be either rotatably captured by and free to rotate within a guidewire, or may rotate upon release from a releasable, mechanically stable friction-fit engagement with a guidewire. The invention is further directed to sterile interfaces for readily connecting and disconnecting an optical guidewire with and from other optical instrumentation while maintaining the sterility of the guidewire, and methods for using a sterile interface device. The invention is also directed to interface devices that provide either direct or indirect optical and mechanical connection between an optical guidewire and peripheral instrumentation. | 03-18-2010 |
| 20100049305 | CONVERTIBLE DELIVERY SYSTEMS FOR MEDICAL DEVICES - A delivery system for a medical device or other devices to be deployed within a biological body including a sheath having a longitudinal joint. The joint can be either resealable or non-resealable. The joint remains intact during delivery of the medical device, thereby facilitating accurate delivery of the medical device. During removal of the sheath, the joint is separated, thereby permitting the sheath to be peeled from the medical device while maintaining the position of the device. The delivery system allows a single operator to deploy the medical device and remove the sheath. | 02-25-2010 |
| 20100047315 | Stent for Increasing Blood Flow to Ischemic Tissues and a Method of Using the Same - Stents and a method of using the stents to increase blood flow to ischemic tissues in a patient are disclosed. | 02-25-2010 |
| 20100004674 | DEVICE FOR, AND METHOD OF, BLOCKING EMBOLI IN VESSELS SUCH AS BLOOD ARTERIES - A filtering device has a directional member and filtering member disposable in a vessel (e.g. blood artery) at a position past a lesion in the direction of fluid flow. The filtering member is made from a resilient material having properties of passing the fluid while blocking the passage of emboli in the fluid. This material may be selected from a group consisting of blood filter material and a braided/woven biocompatible material with the properties specified above. The inner end of the filtering member is attached to a shaft which provides for the disposition of the members in the vessel at the position past the lesion and the withdrawal of the members from the vessel. The directional member has a length extending at least to the vessel wall. The directional member is made from a pliable and elongatable material with properties of blocking fluid and emboli passage. The directional member is deployable within the vessel by the fluid flow in the vessel and directs the fluid in the vessel and any emboli in the fluid into the filtering member. The filtering and directional members are disposed at an acute angle relative to the shaft to create a trapping pocket. Restraining wires attached to the directional member are used to collapse the directional member and draw at least a part of the directional member into an outer sheath to prevent emboli from backflowing into the vessel. | 01-07-2010 |
| 20100004673 | EMBOLIC FILTERING DEVICES FOR BIFURCATED VESSELS - An embolic filtering device for use in a bifurcated vessel includes delivery device having a first guide wire and a second guide wire. The second guide wire diverges from the distal-end region of the first guide wire. The filter device also includes a filter support having a first deployment member and a second deployment member. These deployment members can be formed as a first loop and a second loop. A bifurcated filter element is coupled to the filter support. The distal-end region of the first guide wire extends through a first leg of the filter element and the second guide wire extends through a second leg of the filter element. During use, the first leg of the filter element is deployed within a first branch of the bifurcated vessel and the second leg of the filter element is deployed within a second branch of the bifurcated vessel. | 01-07-2010 |
| 20100004562 | COMPOSITE GUIDEWIRE WITHDRAWN AND FILLED TUBE CONSTRUCTION - The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone. | 01-07-2010 |
| 20090299463 | Modified Surface For An Implantable Device And A Method Of Producing The Same - Implantable devices, such as stents, having a surface modified with TiN | 12-03-2009 |
| 20090291196 | Abluminal Stent Coating Apparatus And Method Using A Brush Assembly - The apparatus and method use an optical feedback system to align a brush assembly with a stent strut. Once alignment is achieved, a coating is dispensed onto the stent strut via the brush assembly and the brush assembly is moved along the stent strut to coat the stent strut. | 11-26-2009 |
| 20090285874 | Implantable Devices For Accelerated Healing - Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided. | 11-19-2009 |
| 20090270973 | STENT ASSEMBLY FOR THE TREATMENT OF VULNERABLE PLAQUE - An intravascular stent assembly for implantation in a body lumen, such as a coronary artery, is designed to treat a lesion with vulnerable plaque by reducing the fibrous cap stresses. A polymeric sleeve having first and second ends interconnects a first metallic stent and a second metallic stent. The first end is bonded to a distal end region of the first stent and the second end to a proximal end region of the second stent. The polymeric sleeve can be loaded with a therapeutic drug or agent to further control local thrombosis and/or induce healing if the plaque fibrous cap ruptures during or after implantation. Methods of making an intravascular stent assembly for the treatment of vulnerable plaque are also provided. | 10-29-2009 |
| 20090259289 | METHOD OF STENT MOUNTING TO FORM A BALLOON CATHETER HAVING IMPROVED RETENTION OF A DRUG DELIVERY STENT - A method of mounting a drug delivery stent on a balloon of a balloon catheter. The method securely mounts the drug delivery stent on the balloon without damaging the drug delivery layer of the stent. In one embodiment, the method generally comprises positioning a drug delivery stent on a balloon of a balloon catheter, and positioning the balloon with the drug delivery stent thereon within a polished bore of a mold formed at least in part of a metallic material. The balloon is pressurized and heated within the mold as the mold radially restrains the stent from expanding, to mount the stent on the balloon without damaging the drug delivery layer of the stent. | 10-15-2009 |
| 20090254118 | EMBOLIC PROTECTION GUIDE WIRE - A sheath attached to a guide wire, a tubular shaft member slidable on the guide wire and a filtering assembly constricted within the sheath are movable in a vessel to a position distal to a lesion in the direction of fluid flow. The filtering assembly may be formed from a plurality of angularly spaced splines and a mesh disposed on the splines having properties of passing fluid in the vessel while blocking the passage of emboli in the fluid. The splines may be provided with shape memory for expanding against the wall of the vessel when released from constriction by the sheath. The sheath may be moved relative to the filtering assembly and the support member to release the filter for expansion against the vessel wall. An interventional device can be used to treat the lesion. Any emboli released into the vessel as a result of the interventional treatment are blocked by the filter member while fluid is allowed to pass there through. | 10-08-2009 |
| 20090247946 | CATHETER WITH A MULTILAYERED SHAFT SECTION HAVING A POLYIMIDE LAYER - A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material. | 10-01-2009 |
| 20090240163 | Methods and Apparatus for Localization, Diagnosis, Contact or Activity Detection of Bio-Electric Tissue - Methods and apparatus for localization, diagnosis, contact or activity detection of bio-electric tissue providing improved sensitivity to the distance between a sensing electrode and bio-electric tissue and providing the means to measure the impedance of the tissue between a sensing electrode and bio-electric tissue. In accordance with the method, a controlled effective input impedance is provided to the monitor, which input impedance can be set to cause a significant portion of the bio-electric tissue signal to be dropped across the tissue between a sensing electrode and the bio-electric tissue when the two are separated by a predetermined or arbitrary distance. Various illustrative embodiments and forms of construction are disclosed. | 09-24-2009 |
| 20090238949 | Methods For Coating Implantable Medical Devices - Methods for coating an implantable medical device, such as a stent, are provided. | 09-24-2009 |
| 20090214756 | Methods For Electrostatic Coating Of An Abluminal Stent Surface - A stent mandrel fixture for supporting a stent during the electrostatic application of a coating substance is provided. | 08-27-2009 |
| 20090197850 | Coatings Comprising Self-Assembled Molecular Structures - A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. | 08-06-2009 |
| 20090192589 | INTRAVASCULAR STENT - The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter. | 07-30-2009 |
| 20090171446 | LOW PROFILE STENT WITH FLEXIBLE LINK - The invention provides an improved stent design for repairing vasculature, the stent having rings including struts defining first peaks and second peaks, selected second peaks of adjacent rings being connected by links. The stent design incorporates non-linear links with undulating portions extending generally perpendicular to or circumferentially with respect to a longitudinal axis of the stent and adjacent first peaks with different longitudinal lengths such that stent flexibility is increased without sacrificing stent compression for delivery. | 07-02-2009 |
| 20090136556 | System And Method For Coating Implantable Devices - A method and system of coating an implantable device, such as a stent, are provided. | 05-28-2009 |
| 20090131971 | GUIDE WIRE WITH EMBOLIC FILTERING ATTACHMENT - A separate deliverable embolic protection device filter that attaches to a helical coil at a distal end of a conventional guide, for use in a blood vessel when an interventional procedure is being performed to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filter assembly with a proximal end and a distal end, and a guide wire connector attached to the distal end of the filter assembly. The guide wire connector is able to couple with the helical coil of the guide wire. A restraining sheath placed over the filter assembly in a coaxial arrangement maintains the filter assembly in a collapsed position and delivers the filter assembly separately to the helical coil of the guide wire, and then the guide wire connector is joined to the helical coil. Alternatively, the guide wire can include a rotatable coil section forming a portion of the distal tip coil on the guide wire which is adapted to be coupled to the filter assembly. This arrangement allows the filter assembly to be rotatably mounted onto the guide wire. | 05-21-2009 |
| 20090131913 | COMPOSITE GUIDE WIRE WITH DRAWN AND FILLED TUBE CONSTRUCTION - The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone. | 05-21-2009 |
| 20090082843 | SELF-EXPANDING STENT WITH ENHANCED DELIVERY PRECISION AND STENT DELIVERY SYSTEM - The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent. The proximal end of the outer tubular member is attached to a pull-back handle which is slidably mounted on the base of the housing assembly. When the pull-back handle is retracted, the restraining sheath is retracted to deploy the sheath, while the inner tubular member remains stationary. | 03-26-2009 |
| 20090062773 | GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS - The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device. | 03-05-2009 |
| 20090053393 | Stent Mandrel Fixture And Method For Reducing Coating Defects - A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. | 02-26-2009 |
| 20090036972 | Stent With Flexible Sections In High Strain Regions - A stent for treating a bodily lumen with a flexible section in a high strain region is disclosed. A flexible section may be selectively positioned to reduce an amount of strain in the high strain region when subjected to the applied stress during use to inhibit or prevent fracturing in the high strain region. | 02-05-2009 |
| 20090030509 | Stent Mandrel Fixture And Method For Reducing Coating Defects - A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. | 01-29-2009 |
| 20090030508 | Stent Mandrel Fixture And Method For Reducing Coating Defects - A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. | 01-29-2009 |
| 20090030445 | DELIVERY SYSEMS FOR EMBOLIC FILTER DEVICES - A delivery system for an expandable filter device includes a dual lumen delivery sheath which has a lumen for receiving the expandable filter device and a lumen for receiving a primary guide wire. The primary guide wire is utilized to place the delivery sheath and expandable filter into the desired region of the patient's vasculature via an over-the-wire or rapid-exchange arrangement. The delivery sheath can be protracted over the expandable filter device to allow the filter to be deployed within the patient's vasculature at the desired location. The delivery system can be embodied in an alternative design in which the primary guide wire extends through a guide wire lumen located in an obturator which forms part of the expandable filter device. Again, the primary guide wire is utilized to maneuver the filter device into the desired area via an over-the-wire arrangement. A slit extending longitudinally along the length of the sheath facilitates the removal of the guide wire and delivery sheath from the patient's vasculature. | 01-29-2009 |
| 20090029030 | POLYMER LINK HYBRID STENT - The present invention is directed to an expandable polymer link hybrid stent for implantation in a body lumen, such as a coronary artery along with a method of making the stent. The stent generally includes a series of metallic cylindrical rings longitudinally aligned on a common axis of the stent and interconnected by a series of polymeric links. The polymer links are formed by applying polymer layers between the rings and laser ablating the excess material. The polymeric material forming the polymeric links, provides longitudinal and flexural flexibility to the stent while maintaining sufficient column strength to space the cylindrical rings along the longitudinal axis. The metallic material forming the rings provides the necessary radial stiffness. | 01-29-2009 |
| 20090005732 | REDUCED SLIPPAGE BALLOON CATHETER AND METHOD OF USING SAME - A balloon catheter having a balloon with a reduced slippage lubricious coating, and a method of performing a medical procedure such as a balloon dilatation procedure in a patient's blood vessel. The second coating (i.e., the balloon coating) is lubricious to facilitate movement of the catheter in the patient's body lumen, yet has sufficiently low lubricity such that the slippage of the inflated balloon from a desired site within the blood vessel is reduced compared to a balloon coated with the first lubricious coating. | 01-01-2009 |
| 20080317939 | Method and System for Irradiation of a Drug Eluting Implantable Medical Device - A method and system for modifying a drug delivery polymeric substrate for an implantable device, such as a stent, is disclosed. | 12-25-2008 |
| 20080279898 | Biologically Degradable Compositions For Medical Applications - A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water. | 11-13-2008 |
| 20080245474 | MEDICAL DEVICE CHEMICALLY MODIFIED BY PLASMA POLYMERIZATION - Medical devices, and particularly intracorporeal devices for therapeutic or diagnostic uses, having a component chemically modified by plasma polymerization. The medical device comprises a substrate with a plasma polymerized functionality bonded to a surface of at least a section thereof. The plasma polymerized film on a first component of the medical device allows for bonding an agent or a second component to the first component. In one embodiment, the plasma polymerized film facilitates fusion or adhesive bonding of a first component to a second component formed of a material which is dissimilar to, incompatible with, or otherwise not readily bondable to the substrate material of the first component. In another embodiment, a bioactive agent is bonded to the plasma polymerized film on the component, for presenting or delivering the bioactive agent within a body lumen of the patient. | 10-09-2008 |
| 20080233268 | Stent Spin Coating Method - A method is disclosed for spin coating a stent. The method comprises applying a coating substance to the stent; rotating the stent about an axis of rotation, the axis of rotation being perpendicular to a longitudinal axis of the stent; and rotating the stent about the longitudinal axis of the stent contemporaneously with rotating the stent about the axis of rotation. The axis of rotation can intersect a center of the mass of the stent. | 09-25-2008 |
| 20080230000 | Stent Spin Coating Apparatus - A system or device for spin coating an implantable medical device, such as a stent, is disclosed. The device includes a coating table to support the stent, the stent being positioned on top of the coating table and supported on the table by a support fixture. The coating table has an axis of rotation. The axis of rotation of the table can intersect a center of the mass of the stent. A driving means can be provided for rotating the stent about the longitudinal axis of the stent and for rotating the coating table about the axis of rotation. | 09-25-2008 |
| 20080215084 | DELIVERY SYSTEMS FOR EMBOLIC FILTER DEVICES - A delivery system for an expandable filter device includes a dual lumen delivery sheath which has a lumen for receiving the expandable filter device and a lumen for receiving a primary guide wire. The primary guide wire is utilized to place the delivery sheath and expandable filter into the desired region of the patient's vasculature via an over-the-wire or rapid-exchange arrangement. The delivery sheath can be protracted over the expandable filter device to allow the filter to be deployed within the patient's vasculature at the desired location. The delivery system can be embodied in an alternative design in which the primary guide wire extends through a guide wire lumen located in an obturator which forms part of the expandable filter device. Again, the primary guide wire is utilized to maneuver the filter device into the desired area via an over-the-wire arrangement. A slit extending longitudinally along the length of the sheath facilitates the removal of the guide wire and delivery sheath from the patient's vasculature. | 09-04-2008 |
| 20080208244 | VARIABLE THICKNESS EMBOLIC FILTERING DEVICES AND METHODS OF MANUFACTURING THE SAME - A strut assembly to be used in conjunction with an embolic filtering device has varying strut thicknesses, with the thickness selected based at least in part on the flexing characteristics of the particular portion of the strut assembly. The strut assembly is formed with patterns having flexing portions and stable portions, with the flexing portions contributing to the flexibility of the strut assembly during delivery and recovery in the patient's vasculature. The stable portions remain relatively unflexed and stiff when being delivered or recovered from the patient's vasculature. The stable portions provide strength and increased radiopacity to the strut assembly which is needed when the strut assembly is deployed in the body vessel. The flexing portions act much like a mechanical hinges in providing the needed flexibility to resiliently bend when being delivered through tortuous anatomy of the patient. | 08-28-2008 |
| 20080206207 | Intracoronary Device And Method Of Use Thereof - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 08-28-2008 |
| 20080200879 | COMPOSITE GUIDEWIRE WITH DRAWN AND FILLED TUBE CONSTRUCTION - The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone. | 08-21-2008 |
