ADVANCED CANCER THERAPEUTICS, LLC Patent applications |
Patent application number | Title | Published |
20150368207 | METHOD FOR TREATING MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)-IMPLICATED DISEASES AND CONDITIONS WITH IODO PYRIMIDINE DERIVATIVES - Compounds useful for the inhibition of macrophage migration inhibitory factor (MIF) are provided herein, having the Formula I: | 12-24-2015 |
20130059879 | Small Molecule Inhibitors of PFKFB3 and Glycolytic Flux and Their Methods of Use as Anti-Cancer Therapeutics - Small molecule inhibitors of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) having the following formula: Formula (1) are provided herein. Also provided herein are pharmaceutical compositions containing Formula I compounds, together with methods of treating cancer, methods of inhibiting PFK.FB3 enzymatic activity, methods of inhibiting glycolytic flux, and methods of treating tumors by administering an effective amount of a Formula I compound. | 03-07-2013 |
20120177749 | FAMILY OF PFKFB3 INHIBITORS WITH ANTI-NEOPLASTIC ACTIVITIES - A methods and compounds for inhibiting 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer, and screening compounds to determine their ability to inhibit PFKFB3. | 07-12-2012 |
20110257211 | Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics - Small molecule choline kinase inhibitors having the following formula: | 10-20-2011 |