| Actelion Pharmaceuticals Ltd. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120115916 | OXAZOLE AND THIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS - The invention relates to oxazole and thiazole derivatives of formula (I), wherein A, E, X, R | 05-10-2012 |
| 20120115841 | BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS - The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R | 05-10-2012 |
| 20120040989 | 2-HYDROXYETHYL-1H-QUINOLIN-2-ONE DERIVATIVES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY - The invention relates to antibacterial compounds of formula I | 02-16-2012 |
| 20110245259 | 5-Amino-2-(1-Hydroxy-Ethyl)-Tetrahydropyran Derivatives - The invention relates to antibacterial compounds of formula I | 10-06-2011 |
| 20110201595 | OXAZOLIDINYL ANTIBIOTICS - The invention relates to antibacterial compounds of formula I | 08-18-2011 |
| 20110195961 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS - The invention relates to antibacterial compounds of formula I | 08-11-2011 |
| 20110195949 | 2-BENZOTHIOPHENYL- AND 2-NAPHTHYL-OXAZOLIDINONES AND THEIR AZAISOSTERE ANALOGUES AS ANTIBACTERIAL AGENTS - The invention relates to antibacterial compounds of formula (I) | 08-11-2011 |
| 20110124636 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R | 05-26-2011 |
| 20110082132 | [4-(1-AMINO-EHTYL) - CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-EHTYL) -TETRAHYDRO-PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS - The invention relates to antibacterial compounds of formula I | 04-07-2011 |
| 20110039836 | TRICYCLIC ANTIBIOTICS - The invention relates to antibacterial compounds of formula (I) | 02-17-2011 |
| 20110039823 | OXAZOLIDINONE ANTIBIOTICS - The invention relates to compounds of formula (I) wherein U, V, W, X, R1, R2, R3, R4, R5, R6, A, B, D, E, G, m, and n are as defined in the description, to pharmaceutically acceptable salts of such compounds for use in the manufacture of a medicament for the prevention or treatment of a bacterial infection. Certain compounds of formula (I) are new and are also part of this invention. | 02-17-2011 |
| 20110021581 | DOSING REGIMEN FOR A SELECTIVE S1P1 RECEPTOR AGONIST - The present invention relates to a dosing regimen for a selective S1P | 01-27-2011 |
| 20100331318 | AZATRICYCLIC ANTIBIOTIC COMPOUNDS - The invention relates to antibacterial compounds of formula I | 12-30-2010 |
| 20100331308 | OXAZOLIDINONE DERIVATIVES - The invention relates to compounds of Formula (I) | 12-30-2010 |
| 20100240717 | NOVEL THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS - The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH | 09-23-2010 |
| 20100234396 | Tetrhydropyridoindole Derivatives - The invention relates to tetrahydropyridoindole derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions comprising one or more of those compounds and methods of treatment comprising administration of said compounds. | 09-16-2010 |
| 20100222600 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel azetidine compounds of formula (I), wherein R | 09-02-2010 |
| 20100190830 | (3-Amino-1,2,3,4-Tetrahydro-9H-Carbazol-9-yl)-Acetic Acid Derivatives - The present invention relates to (3-amino-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-acetic acid derivatives of Formula (I) wherein R | 07-29-2010 |
| 20100179135 | 3-AMINO-6-(1-AMINO-ETHYL)-TETRAHYDROPYRAN DERIVATIVES - Antibacterial compounds including 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives are provided, and methods of treatment or prevention of bacterial infection with such compounds are provided. | 07-15-2010 |
| 20100168005 | Pyridin-3-yl derivatives as immunomodulating agents - The invention relates to pyridin-3-yl derivatives of Formula (I) wherein R | 07-01-2010 |
| 20100137290 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES - The invention relates to antibacterial compounds of formula I | 06-03-2010 |
| 20100087495 | PHENYL DERIVATIVES AND THEIR USE AS IMMUNOMODULATORS - The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. | 04-08-2010 |
| 20100075946 | NOVEL THIOPHENE DERIVATIVES - The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. | 03-25-2010 |
| 20100069376 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE ANTIBACTERIALS - The invention relates to novel chimeric antibiotics of formula I | 03-18-2010 |
| 20100063108 | Pyridin-4-yl derivatives as immunomodulating agents - The invention relates to pyridine derivatives of Formula (I) wherein A, R | 03-11-2010 |
| 20100048648 | Thiophene derivatives as S1P1/EDGE1 receptor agonists - The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. | 02-25-2010 |
| 20100035895 | 2-AMINOCARBONYL-PYRIDINE DERIVATIVES - The present invention relates to 2-aminocarbonyl-pyridine derivatives of Formula (I) and their use as P2Y | 02-11-2010 |
| 20100029623 | 4-(1-AMINO-ETHYL)-CYCLOHEXYLAMINE DERIVATIVES - The invention relates to compounds of formula (I) wherein R | 02-04-2010 |
| 20100029617 | 1,4,5,6,7,8-HEXAHYDRO-1,2,5-TRIAZA-AZULENE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives and their use as orexin receptor antagonists. | 02-04-2010 |
| 20100004274 | Stable pharmaceutical compositions comprising a pyrimidine-sulfamide - Stable pharmaceutical compositions include the compound of the below formula, or pharmaceutically acceptable salts, solvates, hydrates or morphological forms thereof: | 01-07-2010 |
| 20090318459 | Therapeutic Compositions Comprising a Specific Endothelin Receptor Antagonist and a PDE5 Inhibitor - The invention relates to a product containing the compound of formula (I) below | 12-24-2009 |
| 20090291962 | 2-PHENYL-6-AMINOCARBONYL-PYRIMIDINE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR - The invention relates to 2-phenyl-6-aminbcarbonyl-pyrimidinc derivatives and their use as P2Y | 11-26-2009 |
| 20090275588 | NOVEL SULFONAMIDE COMPOUNDS - The invention relates to novel sulfonamide compounds and their use as orexin receptor antagonists. | 11-05-2009 |
| 20090270414 | 2,3,4,9- TETRAHYDRO-1H-CARBAZOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS - The invention relates to novel tetrahydro-1H-carbazole derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administration of said compounds to patients. | 10-29-2009 |
| 20090270375 | SPIRO ANTIBIOTIC DERIVATIVES - The invention relates to compounds of formula (I) wherein R | 10-29-2009 |
| 20090247578 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS - The invention relates to novel chimeric antibiotics of formula I | 10-01-2009 |
| 20090105232 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES - The invention relates to antibiotic cyclohexyl or piperidinyl carboximide derivatives of formula (I) | 04-23-2009 |
| 20090099228 | PYRAZOLO-TETRAHYDRO PYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel pyrazolo-tetrahydropyridines compounds and their use as orexin receptor antagonists. | 04-16-2009 |
| 20090088457 | Primary Amines as Renin Inhibitors - The invention relates to novel primary amine derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin. | 04-02-2009 |
| 20090082394 | Tetrahydroisoquinoline Derivatives to Enhance Memory Function - The invention relates to the use of tetrahydroisoquinoline derivatives for the preparation of a medicament to enhance, maintain and/or restore all stages and/or types of short-, middle- and/or long-term memory. | 03-26-2009 |
| 20090062342 | AMINES - The invention relates to novel amine derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin. | 03-05-2009 |
| 20090023775 | 1-[2-(4-BENZYL-4-HYDROXY-PIPERIDIN-1 -YL )-ETHYL]-3-(2-METHYL-QUINOLIN- 4-YL)- UREA AS CRYSTALLINE SULFATE SALT - The invention relates to 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline, stoichiometrically defined and non-hygroscopic sulfate salt and a process for its preparation. Further, the present invention relates to the use of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline, stoichiometrically defined and non-hygroscopic sulfate salt alone or in combination with other compounds. Further, the present invention relates to formulations of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline, stoichiometrically defined and non-hygroscopic sulfate salt in the preparation of pharmaceutical compositions. The invention also relates to the use of such sulfate salts in formulations as neurohormonal antagonists. | 01-22-2009 |
| 20090005421 | Novel Pyridine Derivatives - The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. | 01-01-2009 |
| 20090005368 | Ethanol or 1,2-Ethanediol Cyclohexyl Antibiotic Derivatives - The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C | 01-01-2009 |
| 20080318955 | Novel Thiophene Derivatives as Sphingosine-1-Phosphate-1 Receptor Agonists - The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. | 12-25-2008 |
| 20080312242 | 7-ARYL-3, 9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES - The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin. | 12-18-2008 |
| 20080300294 | Novel Thiophene Derivatives - The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. | 12-04-2008 |
| 20080280962 | NOVEL THIAZOLIDIN-4-ONE DERIVATIVES - The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents. | 11-13-2008 |
| 20080280888 | Antibiotics Derivatives - The invention relates to antibiotic derivatives of formula I | 11-13-2008 |
| 20080234272 | Novel Piperazines as Antimalarial Agents - The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria. | 09-25-2008 |
| 20080233188 | Stable Pharmaceutical Compositions Comprising a Pyrimidine - Sulfamide - The invention relates to stable pharmaceutical compositions comprising the compound of the below formula, or pharmaceutically acceptable salts, solvates, hydrates or morphological forms thereof. | 09-25-2008 |
| 20080214598 | Novel Piperidine Carboxylic Acid Amide Derivatives - The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin. | 09-04-2008 |
