KOREAN RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY Patent applications |
Patent application number | Title | Published |
20100173430 | CYSTEINE-TAGGED STAPHYLOCOCCAL PROTEIN G VARIANT - The present invention relates to an N-terminal cysteine-tagged Streptococcal protein G variant. Since the variant binds in a directional manner to a surface of a biochip or a biosensor, the variant provides a biochip and a biosensor having an improved antibody-immobilizing capability, compared with an untagged protein G variant. | 07-08-2010 |
20100151505 | METHODS FOR MODULATING THERMOSTABILITY AND ACID TOLERANCE OF MICROBES - The present invention relates a method for modulating thermostability or acid tolerance of a microbe, comprising the steps of: (a) conferring a substitution mutation to a homoserine o-succinyltransferase (MetA)-encoding nucleotide sequence; and (b) transforming the MetA-encoding nucleotide sequence into a microbial cell. The mutated MetA of the present invention shows stability notably enhanced at high-temperatures and/or under acid conditions or decreased at mild temperature, and the microbe, particular bacteria expressing the mutated MetA of the present invention represents a growth rate improved in a vigorous environment such as higher-temperatures and/or lower acid conditions. | 06-17-2010 |