SPIROGEN LIMITED Patent applications |
Patent application number | Title | Published |
20110256157 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF - Conjugates and compounds for making conjugates which are PBD molecules linked via the N10 position are disclosed, along with the use of the conjugates for treating proliferative diseases, including cancer. | 10-20-2011 |
20110201803 | PYRROLOBENZODIAZEPINES - The invention relates to certain pyrrolobenzodiazepines (PBDs), and in particular pyrrolobenzodiazepine dimers bearing C2 substitutions, including compounds of formula (T): wherein: R | 08-18-2011 |
20110196148 | UNSYMMETRICAL PYRROLOBENZODIAZEPINE-DIMERS FOR TREATMENT OF PROLIFERATIVE DISEASES - Claimed are unsymmetrical Pyrrolobenzodiazepine-dimers (PBD-dimers) of formula (I), that are unsymmetrical due at least to the values that the variables R | 08-11-2011 |
20110162227 | PYRROLOBENZODIAZEPINES - Methods of preparing ZC-423 (I) which result in varying enantiomeric ratios. | 07-07-2011 |
20110160192 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS - Compounds of formula (I): Z′-CO-A-B—NH-Z (I) wherein: Z is H or an amino protecting group; Z′ is OH, a protected or activated hydroxyl group or Cl; A is an optionally substituted C | 06-30-2011 |
20100113425 | PYRROLOBENZODIAZEPINES - Compounds of the formula I: | 05-06-2010 |
20080214525 | Alkyl 4- [4- (5-Oxo-2,3,5, 11A-Tetrahydo-5H-Pyrrolo [2, 1-C] [1,4] Benzodiazepine-8-Yloxy) -Butyrylamino]-1H-Pyrrole-2-Carboxylate Derivatives and Related Compounds For the Treatment of a Proliferative Disease - A compound of formula (I); or a salt or solvate thereof, wherein: the dotted line indicates the optional presence of a double bond between C2 and C3; R | 09-04-2008 |