UNIVERSITEIT GENT Patent applications |
Patent application number | Title | Published |
20160030909 | Deposition Tool for Combinatorial Thin Film Material Libraries - A system for combinatorial deposition of a thin layer on a substrate is described. The system comprises at least one deposition material source holder and a substrate holder. The system also comprises a rotatable positioning system for subsequently positioning the at least one substrate in parallel and in non-parallel configuration with at least one deposition material source. The system comprises at least one mask holder arranged for positioning a mask between at least one of the target holder and the positioning system, for allowing variation of the material flux across the at least one substrate when the combinatorial deposition is performed. The mask holder is in a fixed arrangement with respect to the at least one deposition material source holder during the combinatorial depositing. | 02-04-2016 |
20160025931 | INTEGRATED GRATING COUPLER AND POWER SPLITTER - An optical device is provided for coupling an external optical signal into a plurality of on-chip photonic sub-circuits provided on a substrate. The optical device comprises: a planar waveguide layer on the substrate; a diverging grating coupler configured to couple the external optical signal to the planar waveguide layer and to thereby create an on-chip diverging optical beam in the planar waveguide layer; and a plurality of channel waveguides formed in the waveguide layer. Each channel waveguide of the plurality of channel waveguides comprises a waveguide transition structure having a waveguide aperture oriented towards the diverging grating coupler. For each channel waveguide of the plurality of channel waveguides the position and the width of the corresponding waveguide aperture and the angle and the shape of the waveguide transition structure are individually selected to capture a predetermined portion of the on-chip diverging optical beam. | 01-28-2016 |
20150366594 | ARTICULAR FRACTURE FIXATION SYSTEM AND METHOD - Provided herein is an osteosynthesis device for articular fracture fixation, more particularly for fixation of shoulder, knee, elbow, ankle and wrist fractures. The osteosynthesis device comprises an articular supportive plate for supporting the articular surface of a long bone, said articular supportive plate comprising (i) at least one pin receiving feature for receiving a pin or a screw; and (ii) at least one fin projecting from a first side of said articular supportive plate, said fin being provided with one or more pin receiving features for receiving a pin or screw. Further provided herein are systems for articular fracture fixation, and methods of fixating an articular fracture in a long bone using such systems. | 12-24-2015 |
20150333481 | Hybrid Waveguide Lasers and Methods for Fabricating Hybrid Waveguide Lasers - The present disclosure relates to a method for integrating a sub-micron III-V waveguide laser on a semiconductor photonics platform as well as to a corresponding device/system. The method comprises providing on a semiconductor substrate an electrically insulating layer, etching a trench having a width in the range between 50 nm and 800 nm through the electrically insulating layer, thereby locally exposing the silicon substrate, providing a III-V layer stack in the trench by local epitaxial growth to form a channel waveguide, and providing a light confinement element for confining radiation in the local-epitaxial-grown channel waveguide. | 11-19-2015 |
20150285996 | Integrated Photonic Coupler - The present invention relates to an integrated photonic device comprising a photonic substrate, and an integrated waveguide provided in or on this substrate. The waveguide is adapted for conducting radiation of a predetermined wavelength. The device further comprises a sub-wavelength grating optically connected to the waveguide, which provides a first periodic variation of the refractive index in at least one first spatial direction. The device also comprises a diffracting grating arranged over the sub-wavelength grating for coupling radiation of the predetermined wavelength in and/or out of the integrated waveguide via the sub-wavelength grating. The diffracting grating provides a second periodic variation of the refractive index in at least one second spatial direction. The first periodic variation has a first pitch that is less than half of the predetermined wavelength, while the second periodic variation has a second pitch that is at least half of the predetermined wavelength. | 10-08-2015 |
20150280950 | Signal Processing - Described herein is a multi-level to binary converter in which a cascade of differential limiting amplifiers are utilised for each signal path to provide both increased gain and increased bandwidth without having to trade one off against the other. Where the multi-level data is duobinary, cascaded amplifiers are coupled to a XOR logic gate. In each path, a copy of the duobinary signal is level shifted using an adjustable threshold before amplification in an amplifier. The shifted and amplified signal is then fed to another amplifier where it undergoes the same steps. The outputs from each path are fed to the XOR logic gate to generate the desired binary signal, corresponding to a decoded synchronized NRZ data stream. Such a multi-level to binary converter is capable of performing at data rates of 50 to 80 Gb/s and above, and can easily be integrated within a chip for high-speed electrical backplane communication, optical backplanes or optical fibre links. | 10-01-2015 |
20150276953 | CALIBRATION OF MONOLITHIC CRYSTAL-BASED DETECTORS - A calibration method for calibrating at least one gamma radiation detector includes a monolithic scintillation crystal. The calibration method comprises obtaining event data for a plurality of scintillation events. The event data for each scintillation event includes a plurality of location sensitive signals observed by the at least one gamma radiation detector to be calibrated, applying an unsupervised learning algorithm to embed the event data on a low-dimensional manifold, and obtaining calibration data considering the low-dimensional manifold embedding. | 10-01-2015 |
20150276873 | Test Circuits - Described herein is a feed forward equalizer that is configured to operate in a normal operational mode and in a test operational mode. The feed forward equalizer has an input port and an output port which are used for the normal operational mode. A test input port and a test output port are provided in the feed forward equalizer, and are used for the test operational mode. Buffers may be provided for matching the impedance of respective ones of the input, output, test input, and test output ports. The feed forward equalizer allows testing during development, and once mounted in an integrated circuit, without interfering with the normal operational mode. | 10-01-2015 |
20150265687 | COOPERIA VACCINE - The present invention relates to nucleotide sequences encoding | 09-24-2015 |
20150251230 | TREATMENT OF CLAY OR DREDGED SEDIMENT WITH POLYMER INCREASES ADSORPTION CHARACTERISTICS - The disclosure relates to the field of lining materials which are used to isolate landfill sites in order to avoid pollution of surrounding soil by ions such as heavy metals. Further disclosed is a process to increase the ion adsorption capacity of clay or dredged sediment. More specifically, the disclosed is a process comprising: a) mixing the clay or dredged sediment with an anionic polymer, and b) subsequently drying the mixture, results in a lining material having superior ion adsorption characteristics. | 09-10-2015 |
20150244547 | Circuitry and Method for Multi-Level Signals - Circuitry for converting a multi-level signal into at least one binary signal, having a period T and comprising n signal levels, includes comparing and splitting circuitry configured for comparing a value of the multi-level signal with (n−1) different reference values, and having N sets of (n−1) output terminals for outputting N sets of (n−1) output signals indicating whether the value of the multi-level signal is below or above the (n−1) reference values. The circuitry also includes N sets of (n−1) sample-and-hold circuits having an input and an output and being configured for operating at a clock period N*T, wherein each output terminal is connected to the input of a sample-and-hold circuit. Further, the circuitry includes logical circuitry connected to the outputs of the N sets of (n−1) sample-and-hold circuits for generating at least one binary signal having a period N*T. | 08-27-2015 |
20150225240 | MEMBRANES, AZEOTROPIC & CATALYTIC COMPONENTS - This invention relates generally to new findings to improve a method of thermal energy storage or heat pump, i.e. increase the thermal energy from an external heat source, using a reversible condensation reaction with an inorganic oxoacid compound. It accordingly provides components to be used in said improved process as well as the use thereof in the aforementioned method, including the use in the manufacture of products of the condensation products or in the manufacture of the hydrolysis products. | 08-13-2015 |
20150193242 | INSTRUCTION WINDOW CENTRIC PROCESSOR SIMULATION - A method and system are described for simulating a set of instructions to be executed on a processor. The method comprises performing a performance simulation of the processor over a number of simulation cycles. Performing the performance simulation of the processor comprises modeling an instruction window for the cycle and deriving a performance parameter of the processor without modeling a reorder buffer, issue queue(s), register renaming, load-store queue(s) and other buffers of the processor. | 07-09-2015 |
20150148627 | Sensing of Components in Liquids - A sensing system and method for sensing a component in a liquid is disclosed. The system comprises a microfluidic channel, the microfluidic channel comprising a first end and a second end, wherein the microfluidic channel is open at the first end and closed at the second end. The system also comprises at least one measurement sensor positioned adjacent the first end, the measurement sensor being arranged for detecting a measurement signal and a reference sensor positioned in the microfluidic channel adjacent the second end, the reference sensor being arranged for detecting a reference signal of the liquid. The system further is configured for combining the measurement signal and the reference signal so as to filter out background influences. | 05-28-2015 |
20150107799 | MANUFACTURING HEAT EXCHANGER FROM POROUS MEDIUM AND CONDUITS - The present invention relates to a method for producing a heat exchanger. The heat exchanger comprising at least one heat conducting conduit for passage of a first medium and at least one block of an open cell porous medium for passage of a second medium. The method comprises providing at least one groove in the open cell porous medium. Thereafter, the porous medium is bent in a direction such that at least part of the grooves are opened and heat conducting conduits are applied in this at least one opened groove. Thereafter, the porous medium is rebend such that the heat conducting conduits are locked in said open cell porous medium. | 04-23-2015 |
20140363127 | Integrated Photonics Waveguide Grating Coupler - A photonic integrated device comprises a waveguide embedded in a photonic substrate. The waveguide has a waveguide radiation exit surface and the waveguide is optically connected to a two dimensional grating. The photonic integrated device also comprises a two dimensional grating having a plurality of curved elongate scattering elements. The two dimensional grating is adapted for diffracting radiation received from the waveguide toward a direction out of the photonic substrate and the curved elongate scattering elements are oriented with respect to the waveguide such that, for points of the scattering elements which can be irradiated by radiations stemming from the waveguide, normal lines to at least the curved elongate scattering element closest to the waveguide radiation exit surface do not substantially intersect with the waveguide radiation exit surface of the waveguide. | 12-11-2014 |
20140335567 | LACTONASE DERIVED FROM CANDIDA BOMBICOLA AND USES THEREOF - The present disclosure relates to an enzyme derived from | 11-13-2014 |
20140319378 | OPTICAL FLUORESCENCE-BASED CHEMICAL AND BIOCHEMICAL SENSORS AND METHODS FOR FABRICATING SUCH SENSORS - An optical fluorescence-based sensor comprising at least one sensing element is disclosed. In one aspect, the at least one sensing element comprises a waveguide comprising a waveguide core, a light source optically coupled to an input part of the waveguide core, and a photodetector optically coupled to an output part of the waveguide core, the waveguide core being made of a material comprising a mixture of an optical material and a fluorescent dye. | 10-30-2014 |
20140291897 | PRODUCTION AND USE OF LAMINATED NANOFIBROUS STRUCTURES - An electrospinning device for providing a predetermined distance profile for the distance between outlets of the electrospinning device and the receiving surface. The latter may be obtained by geometrically adapting the electrospinning device or by moving the outlets with respect to the receiving surface during growth of the fibrous structure. | 10-02-2014 |
20140285124 | CONTROL METHOD AND DEVICE THEREFOR - In one embodiment, a method of forming a circuit to control an electrical machine may include, configuring the circuit to obtain voltage and current information of the voltage over and current in one or more stator coils; configuring the circuit to determine a stator current vector and a stator voltage vector; configuring the circuit to determine an amplitude and phase of a fundamental vector of the stator voltage vector and stator current vector; and configuring the circuit to determine a fundamental vector of a back-EMF. | 09-25-2014 |
20140255604 | Synthesis of Nanomaterials - A method is disclosed for synthesis of nanoparticles of metal selenide, metal selenide alloys, metal chalcogenide comprising at least selenium or metal chalcogenide alloys comprising at least selenium. The method comprises obtaining a heterogeneous dispersion of powder at least selenium in a first solvent at a first temperature, the first temperature being such that the heterogeneous dispersion comprises at least a fraction of undissolved powder in the solvent. The method also comprises introducing the heterogeneous dispersion into a second solvent containing a metal cation precursor, the second solvent being at a second temperature higher than said first temperature allowing, upon introduction of the heterogeneous dispersion, dissolution of at least the fraction of the power resulting in nucleation of the nanoparticles. The method results in efficient and easy production of nanoparticles. | 09-11-2014 |
20140247089 | Two Stage Source-Follower Based Filter - A filter, comprising: two source-follower stages connected in series and in between input nodes and output nodes, wherein inner nodes connect the two stages; and a frequency dependent feedback circuit connected between the input and output nodes, wherein the filter comprises additional frequency dependent feedback circuits connected between input nodes and inner nodes and between output nodes and inner nodes, the additional frequency dependent feedback circuits comprising capacitors. | 09-04-2014 |
20140242105 | VACCINES FOR CHLAMYDIA - The present invention relates to means and methods to protect against disease caused by bacteria belonging to the genus | 08-28-2014 |
20140220597 | NEUREGULIN-1-BASED PROGNOSIS AND THERAPEUTIC STRATIFICATION OF COLORECTAL CANCER - The present invention relates to the prognosis, therapeutic stratification and treatment of colorectal cancer. More in particular, the present invention discloses that significantly increased levels of transmembrane type 1 neuregulin-1 in tumor-associated mesenchymal cells present in a sample of a patient indicate that the patient has a worse prognosis when compared to patients having low levels of transmembrane type 1 neuregulin-1 in tumor-associated mesenchymal cells. Moreover, the present invention relates to the usage of transmembrane type 1 neuregulin-1 expression in tumor-associated mesenchymal cells to predict resistance to HER1 inhibitors during colorectal cancer therapy and/or to predict whether a patient would benefit from a therapy based on the prevention of neuregulin-1 and/or HER3 activity. | 08-07-2014 |
20140220568 | MEANS AND METHODS FOR THE DETERMINATION OF PREDICTION MODELS ASSOCIATED WITH A PHENOTYPE - The disclosure provides methods and means for identifying plants comprising a plant phenotype of interest. In particular, the disclosure provides breeding tools that can be used for the selection of a plant comprising a phenotype of interest and for the selection of an optimal plant genotype for the introduction of a trait. | 08-07-2014 |
20140212454 | PREVENTION OF SALMONELLA RECRUDESCENSE - The present invention relates to novel | 07-31-2014 |
20140207044 | MINIMALLY-ADVANCING LUMINAL CATHETER - The present invention relates to an implantable catheter ( | 07-24-2014 |
20140192689 | NODE AND A WIRELESS SENSOR NETWORK COMPRISING THE NODE - A computer-implemented method to generate or receive, process and transmit information packets in a node that is in a network with embedded devices using at least one of heterogeneous data formats and protocols at different network layers. The method includes, for each packet, steps of dynamically determining and selecting by the node one or more of a plurality of protocols for processing the packet in the node based on protocol rules that specify when a protocol can be used; and activating by the node at runtime the one or more selected protocols for processing the packet. At least two different protocols of the plurality of protocols are selectable and activateable by the node for processing two different packets for the same network layer. A node configured to perform the method. | 07-10-2014 |
20140186395 | PERMISSIVE CELLS AND USES THEREOF - Described are methods for determining the permissiveness of a cell for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular, for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Further described are methods and compositions related to the generation of host cells permissive for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular, for PRRSV. Methods of utilzing the cells thus identified or thus generated, in preparing a culture of a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, as well as the use of the virus for the purpose of vaccine production or diagnosis, are also described. | 07-03-2014 |
20140185042 | MOLECULAR ANALYSIS DEVICE - In the present invention, a molecular analysis device comprises a substrate, and a waveguide with a planar integrating element and filter or reflector element adjacent thereto is disposed on the substrate. The waveguide comprises a coupling means configured for coupling a predetermined frequency range of laser radiation into the waveguide. At least one metallic nanostructure is disposed on or adjacent to the planar integrating element, at least one metallic nanostructure is configured such that the field intensity and the gradient of the laser radiation, that is coupled into the waveguide, are enhanced over a sufficiently large volume around the nanostructure to simultaneously cause plasmonic based optical trapping of analyte(s) in a medium, and plasmonic based excitation of the particles to produce Raman scattered radiation. A Raman scattered radiation collection means is disposed on the substrate for collecting said Raman scattered radiation produced by the particles. | 07-03-2014 |
20140178471 | MULTI-LAYERED RELEASE FORMULATION - The present invention in general relates to a pharmaceutical dosage form comprising a multi-layered release formulation formed by co-extrusion. Said formulation in particular comprises a core layer comprising at least one polymer selected from polycaprolactone, ethylcellulose, or combinations thereof; and a coat layer comprising at least one (co)polymer selected from the list comprising: polyethylene oxide; polyethylene glycol; Basic Butylated Methacrylate (co)polymer; a (co)polymer of polyvinylcaprolactam, PEG and polyvinylacetate; or combinations thereof. | 06-26-2014 |
20140176957 | Integrated Optical Sensor Circuit - A photonics integrated system is disclosed, comprising a substrate, an integrated interferometer integrated in the substrate and being configured for receiving radiation from a radiation source, and an integrated spectral filter integrated in the substrate and being configured for receiving radiation from the interferometer. The integrated interferometer has a period and the integrated spectral filter has a bandwidth such that the period of the integrated interferometer is smaller than the bandwidth of the integrated spectral filter. The integrated spectral filter has a periodic transfer characteristic with a period and the system has a bandwidth such that the period of the periodic transfer characteristic of the integrated spectral filter is larger than the bandwidth of the system. | 06-26-2014 |
20140161384 | Integrated Photonic Devices with Reduced Sensitivity to External Influences - One aspect of the invention relates to a photonic device having a wavelength-dependent transmission or filter characteristic, comprising: a Splitter Polarization Rotator receiving polarized light and providing a first resp. second wave; a first resp. second waveguide arm connected to the SPR for propagating a first resp. second polarization mode (TM, TE) of the first resp. second wave, the second polarization mode being different from the first polarization mode; and a Polarization Rotator and Combiner for combining the propagated first resp. second waves; wherein the dimensions of the first and second arm are selected to cancel the influence of an external effect on the wavelength-dependent characteristic. Another aspect of the invention relates to a method for reducing the sensitivity of said integrated photonic device, comprising splitting a polarized light beam, propagating light waves of different polarity through two waveguide arms of specific dimensions, and recombining them. | 06-12-2014 |
20140154738 | PROTEIN GLYCOSYLATION MODIFICATION IN METHYLOTROPHIC YEAST - The present invention provides genetically engineered strains of | 06-05-2014 |
20140154293 | INTRAVAGINAL DELIVERY SYSTEM - The present invention in general relates to an intravaginal delivery system as well as uses thereof and methods for manufacturing and use of the same. In particular the present invention relates to an intravaginal delivery system for the controlled release of one or more organic acids, such as lactic acid; said intravaginal delivery system being characterized in that it comprises a combination of ethylene vinyl acetate (EVA) copolymers and carboxylic polymers, such as for example methacrylic acid-methacrylic ester copolymers. | 06-05-2014 |
20140121218 | METHOD FOR TREATING OCULAR CANCER - It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53 activator. In particular embodiments, the p53 activator blocks the interaction between DM2 or DMX and p53. As the p53 activator induces ocular cancer cell death, a method for preventing or treating ocular cancer is also provided. | 05-01-2014 |
20140039081 | SULPHUR-CONTAINING THERMOPLASTIC POLYMERS - A process For the production of a thermoplastic polymer including carbon and sulphur in an atomic ration of C:S of at least 4 and at most 36 using thiol-ene addition polymerization, preferably with feedstocks obtained from renewable resources such as fatty acids from vegetable origin. The product is preferably aliphatic, meaning that at most 70% of the protons are present as aromatic hydrogen atoms and, if oxygen atoms are present in ester functions, the atomic ratio of the oxygen atoms present in ester functions relative to the number of sulphur atoms in the polymer is less than 1.0. The polymer may be used to produce a shaped article. | 02-06-2014 |
20140037646 | MMP8 INACTIVATING ANTIGEN BINDING PROTEINS - Described are MMP8 inactivating antigen binding proteins, such as antigen binding proteins comprising an amino acid sequence that comprises 4 framework regions and 3 complementary determining regions; further described is the use of such antigen binding proteins to treat inflammation, such as, but not limited to, systemic inflammatory response syndrome, sepsis, LPS induced inflammation, renal ischemia/reperfusion injury, ventilation induced lung injury, periodontal inflammation, rheumatoid arthritis, multiple sclerosis, ankylosing spondylitis, Lyme arthritis and osteoarthritis. | 02-06-2014 |
20140030746 | KINASE SUBSTRATE SENSOR - The disclosure relates to a cytoplasmic protein complex comprising: (a) a first recombinant fusion protein comprising a kinase, fused to a first interaction polypeptide; and (b) a second recombinant fusion protein comprising a domain comprising a reporter phosphorylation site, whereby the domain is fused to a second interaction polypeptide. The disclosure relates further to a method to detect compound-compound-interaction using the cytoplasmic protein complex, and to cells comprising such cytoplasmic protein complex. | 01-30-2014 |
20130333741 | LOW VOLTAGE DROP UNIDIRECTIONAL SMART BYPASS ELEMENTS - Described herein is a low-voltage unidirectional bypass element connected across a solar cell and operable to allow current to flow when the operation of the solar cell is suspended. The bypass element includes a single field effect transistor connected between first and second terminals as a switch, and a detection circuit for detecting suspension of the solar cell's operation and activating the switch to bypass the solar cell in the event of its operation suspension. Diodes are connected in parallel with the normally-open switch and receive current, when the solar cell's operation is suspended, to trigger operation of the detection circuit. The detection circuit includes a charge pump, a timer circuit, a control generation unit and a switch control circuit. The switch control circuit generates a control signal to close the switch and to allow current to bypass the solar cell. | 12-19-2013 |
20130315916 | RESPIRATORY SYNCYTIAL VIRUS VACCINE - Described is a vaccine against Respiratory Syncytial Virus (RSV). More specifically, described is a recombinant subunit vaccine comprising the ectodomain of the RSV-encoded Small Hydrophobic (SH) protein. The ectodomain of SH is referred to as SHe. The ectodomain is typically presented as an oligomer, or a pentamer. Further described are antibodies, raised against the ectodomain or specific for the ectodomain, and their use for protecting a subject against RSV infection and/or for treatment of an infected subject. | 11-28-2013 |
20130306268 | METHODS AND COMPONENTS FOR THERMAL ENERGY STORAGE - A method is provided for storing thermal energy or increasing the thermal energy of a heat pump using reversible chemical reactions in which inorganic oxoacid compounds and/or their salts are hydrolysed and condensed or polymerized in order to release and capture heat. | 11-21-2013 |
20130302857 | TREHALOSE PHOSPHORYLASES AND THEIR USE IN THE BIOCATALYTIC PRODUCTION OF TREHALOSE-ANALOGUES AND GLYCOSYL PHOSPHATES - The present invention relates to trehalose phosphorylases which are useful for the industrial production of trehalose-analogues and glycosyl phosphates. More specifically, the invention discloses trehalose phosphorylases which are mutated in specific amino acid regions. These specific mutations result in modified substrate specificities of the enzymes. In addition, the present invention discloses a wild type trehalose phosphorylase from the marine organism | 11-14-2013 |
20130293787 | Fast Channel Switching - A method, a coding format and a device is provided for switching from a first data channel to a second data channel of a digital television system. At least the second data channel is coded in a multilayer scalable video coding format comprising a base layer and at least one enhancement layer. The multilayer coding is used for switching between channels, and at least one of the enhancement layers may be adapted for providing fast switching by providing it with more random access points, e.g. more IDR-frames, than the base layer. | 11-07-2013 |
20130289239 | METHOD FOR CROSS-LINKING PEPTIDES - The present invention relates to a method for cross-linking peptides using an activated furan-moiety. In particular, the present invention provides a method for cross-linking peptides comprising the steps of: a) providing a composition comprising furan-peptides, said furan-peptides comprising at least one amino acid comprising a furan-moiety; b) contacting said composition comprising furan-peptides with second peptides, thereby obtaining a mixture comprising furan-peptides and second peptides; c) adding an activation signal to said mixture of step b), thereby activating said furan-peptides to activated furan-peptides, and d) reacting said activated furan-peptides with said second peptides, thereby cross-linking said activated furan-peptides with said second peptides. | 10-31-2013 |
20130248463 | FIBROUS FILTERS - A method for fabricating a micro- or nanofibrous filter is described. The method comprises obtaining at least a first carrier substrate, providing adhesive on at least a first carrier substrate, heating the adhesive above its melting temperature for inducing an interaction of at least part of the adhesive with the at least a first carrier substrate and then cooling below the melting temperature of the adhesive thus creating at least one adhesive carrier substrate. Thereafter, a layer of micro- or nanofibres is provided on the adhesive-side of the at least one adhesive carrier substrate to form a further structure. The further structure is then brought above the melting temperature of the adhesive for inducing an interaction between the adhesive and the micro- or nanofibres. Finally the temperature is again reduced below the melting temperature of the adhesive thus obtaining the micro- or nanofibrous filter. | 09-26-2013 |
20130245606 | HYDROGEL BASED OCCLUSION SYSTEMS - A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a target occlusion location. The hydrogel is configured to permanently occlude the target occlusion location in the swollen state. The hydrogel may be an electro-activated hydrogel (EAH) which could be electro-activated with a delivery system to control the degree of swelling/shrinking. | 09-19-2013 |
20130203161 | TECHNOLOGY AND METHOD TO STUDY MICROBIAL GROWTH AND ADHESION TO HOST-RELATED SURFACES AND THE HOST-MICROBIOTA INTERACTION - A method is provided for co-culturing viable cells and microorganisms for at least 48 hours in which an adhesion module is provided including a basal compartment and a luminal compartment separated by a semi-permeable membrane, and a continuous or semi-continuous flow of fresh medium is applied to the basal compartment. | 08-08-2013 |
20130195835 | Glycosylation of Molecules - Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders. | 08-01-2013 |
20130190253 | Glycosylation of Molecules - Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders. | 07-25-2013 |
20130168071 | 3D POROUS MATERIAL COMPRISING MACHINED SIDE - 3D porous material comprises at least one machined side. The machined side has a solid percentage P | 07-04-2013 |
20130158239 | HYDROLYSIS OF MANNOSE-1-PHOSPHO-6-MANNOSE LINKAGE TO PHOSPHO-6-MANNOSE - Described herein are methods and genetically engineered cells useful for uncapping a mannose-6-phosphate residue on an oligosaccharide. | 06-20-2013 |
20130145959 | CLAYEY BARRIERS - The present invention relates to improved clayey barriers, such as compacted clay liners or geosynthetic clay liners, which can be used, among other uses, to isolate waste liquids from the environment. More in particular, the present invention relates to clay which is treated with an anionic polymer and is subsequently dehydrated before it is used as a barrier. The latter improved clays are surprisingly well, and for a long term, protected from chemical attack by aggressive electrolyte solutions present in, for example, sea water or waste liquids. | 06-13-2013 |
20130137140 | INCREASED PROTEIN EXPRESSION THROUGH INCREASED MEMBRANE FORMATION - The present application relates to the field of protein expression technologies. More specifically, it is demonstrated that cells with increased levels of phosphatidic acid, which can be achieved through either or both of phosphatidic acid inhibition and diacylglycerol kinase overexpression, display increased membrane formation from which increased levels of proteins can be recovered. | 05-30-2013 |
20130122553 | METABOLICALLY ENGINEERED ORGANISMS FOR THE PRODUCTION OF ADDED VALUE BIO-PRODUCTS - The present invention relates to genetically engineered organisms, especially microorganisms such as bacteria and yeasts, for the production of added value bio-products such as specialty saccharide, activated saccharide, nucleoside, glycoside, glycolipid or glycoprotein. More specifically, the present invention relates to host cells that are metabolically engineered so that they can produce said valuable specialty products in large quantities and at a high rate by bypassing classical technical problems that occur in biocatalytical or fermentative production processes. | 05-16-2013 |
20130096268 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS - This invention relates to monodisperse or nearly monodisperse (co)polymers containing acrylic or (α-substituted)acrylic acid moieties, polymeric precursors thereof as well as methods for making them by at least partial hydrolysis of said polymeric precursors. The invention also relates to compositions comprising such (co)polymers optionally in combination with polymer processing additives for use in various fields of technology including imaging applications. | 04-18-2013 |
20130089892 | YEAST STRAINS MODIFIED IN THEIR SOPHOROLIPID PRODUCTION AND USES THEREOF - The present invention relates to yeast species which are normally capable of producing sophorolipids but which are modified in such way that they are incapable producing the latter compounds. These sophorolipid-negative strains surprisingly display equal growth characteristics and biomass formation as their wild type counterparts and are hence useful for the production of compounds such as recombinant proteins, glycolipids, polyhydroxyalkanoates and carotenoides. In addition, the present invention discloses two glucosyltransferase genes with key-functions in sophorolipid production. | 04-11-2013 |
20130075876 | SEALED POROUS MATERIALS, METHODS FOR MAKING THEM, AND SEMICONDUCTOR DEVICES COMPRISING THEM - A method for at least partially sealing a porous material is provided, comprising forming a sealing layer onto the porous material by applying a sealing compound comprising oligomers wherein the oligomers are formed by ageing a precursor solution comprising cyclic carbon bridged organosilica and/or bridged organosilanes. The method is especially designed for low k dielectric porous materials to be incorporated into semiconductor devices. | 03-28-2013 |
20130064795 | IMMUNE MODULATION - The invention provides a layered double hydroxide compound for use in modulating an immune response to an antigen, and an immune modulator composition comprising the layered double hydroxide and an antigen. The compound is of formula (I), (II), or (III) | 03-14-2013 |
20130063846 | ESD Protection Device With Reduced Clamping Voltage - Disclosed is an ESD protection circuit comprising a plurality of bipolar transistors, namely a plurality of ESD current conducting transistors (Q | 03-14-2013 |
20130059340 | BIOCATALYTIC PRODUCTION OF GLYCOSIDES - The present invention relates to the biocatalytic production of glycosides. In particular, the invention discloses a method to produce alkylcellobiosides, arylcellobiosides, cellobiolipids, cellotriolipids, glucosophorolipids and cellobiosesophorolipids via the usage of a cellodextrin phosphorylase (CDP) derived from | 03-07-2013 |
20130052230 | SALMONELLA VACCINE - The present invention relates to novel | 02-28-2013 |
20130036829 | OPTICAL SHEAR SENSOR AND METHOD OF PRODUCING SUCH AN OPTICAL SHEAR SENSOR - An optical shear sensor that includes a first and second outer surface at opposing sides and a sensing element is disclosed. In one aspect, the sensing element has an optoelectronic source for emitting light of a predetermined wavelength and having a source front surface where light exits the optoelectronic source, and a photodetector for detecting light of the predetermined wavelength and having a detector front surface where light of the optoelectronic source is received. The optoelectronic source is positioned along the first outer surface and emits light towards the second outer surface. A flexible sensing layer transparent to the predetermined wavelength covers the front surface of the optoelectronic source and the front surface of the photodetector. Upon application of a shear stress, the sensing layer deforms elastically and the outer surfaces are displaced along directions parallel to each other and the source front surface so the intensity of light detected by the photodetector changes. | 02-14-2013 |
20130029384 | THERMOSTABLE SUCROSE PHOSPHORYLASE - The present invention relates to a sucrose phosphorylase from | 01-31-2013 |
20130022312 | Deep-Shallow Optical Radiation Filters - An optical coupler for processing radiation is described. The optical coupler comprises a first deep-shallow waveguide and a second deep-shallow waveguide for guiding radiation in a propagation direction. Each of the deep-shallow waveguides is a waveguide comprising a shallow etched portion and an unetched portion having a width substantially constant along the propagation direction. The width of the shallow etched portion is substantially larger than the width of the unetched portion. The shallow etched portion of the first deep-shallow waveguide and the shallow etched portion of the second deep-shallow waveguide are arranged sufficiently close for coupling radiation from the first deep-shallow waveguide to the second deep-shallow waveguide. | 01-24-2013 |
20120293797 | METHODS AND SYSTEMS FOR OPTICAL CHARACTERISATION - An optical device is described for irradiating at least one object in a medium. The optical device may be a microfluidics device, and comprises at least one integrated planar waveguide that enables providing sheet irradiation of objects in the medium. A characterization system including such an optical device and a corresponding method of characterizing an object or a fluid are described. | 11-22-2012 |
20120288971 | Co-Integration of Photonic Devices on a Silicon Photonics Platform - Disclosed are methods for co-integration of active and passive photonic devices on a planarized silicon-based photonics substrate. In one aspect, a method is disclosed that includes providing a planarized silicon-based photonics substrate comprising a silicon waveguide structure, depositing a dielectric layer over the planarized silicon-based photonics substrate, selectively etching the dielectric layer, thereby exposing at least a portion of the silicon waveguide structure, selectively etching the exposed portion of the silicon waveguide structure to form a template, using the silicon waveguide structure as a seed layer to selectively grow in the template a germanium layer that extends above the dielectric layer, and planarizing the germanium layer to form a planarized germanium layer, wherein the planarized germanium layer does not extend above the dielectric layer. | 11-15-2012 |
20120245326 | SPIDER MITE SILK PROTEINS - Described are silk proteins derived from spider mite, more specifically derived from | 09-27-2012 |
20120160031 | OPTICAL TACTILE SENSORS - A sensor for sensing pressure is disclosed. The sensor may be a pressure sensor for sensing pressure, or a tactile sensor for sensing tactile events through pressure measurement. In one aspect, the sensor includes at least one pressure sensor having at least one VCSEL on a substrate. It further includes a compressible sensor layer covering a top surface of the at least one VCSEL, and a reflecting element covering a top surface of the sensor layer. A method of manufacturing such a sensor is also disclosed. | 06-28-2012 |
20120097547 | Method for Copper Electrodeposition - The present invention is related to a method for electroplating a copper deposit onto a substrate, wherein the method comprises the steps of: a) immersing the substrate into an electroplating bath having a copper ion concentration comprised between 0.5 mmol·l | 04-26-2012 |
20120093456 | Coupling Methods and Systems Using a Taper - Disclosed are optical devices for coupling radiation between an optical waveguide and an external medium. In one embodiment, an optical device is disclosed comprising a semiconductor die comprising an integrated optical waveguide core and an overlying optical waveguide comprising a waveguide taper and a waveguide facet. The overlying optical waveguide at least partially overlies the integrated optical waveguide core, and the waveguide facet is between about 1 μm and 200 μm from an edge of the semiconductor die. In another embodiment, a method is disclosed comprising providing a substrate comprising an integrated semiconductor waveguide and forming on the substrate an overlying waveguide comprising a waveguide taper and a waveguide facet. The overlying waveguide at least partially overlies the integrated semiconductor waveguide. The method further includes cutting the substrate about 1 μm and 200 μm from the waveguide facet. | 04-19-2012 |
20120064836 | Amplifier Circuit for a Ranging Transceiver - An amplifier circuit is disclosed. In one embodiment, the amplifier circuit includes an input configured to receive an input signal. The amplifier circuit further includes an amplifier connected to the input that is configured to receive the input signal and generate a modulated input signal based on the input signal and one of a first amplification level and a second amplification level. The amplifier comprises a first transistor configured to receive the input signal and a second transistor connected in cascode with the first transistor. The amplifier circuit further includes a switching component configured to switch the amplifier between the first amplification level and the second amplification level. The amplifier circuit still further includes an output connected to the amplifier and configured to output the modulated input signal. | 03-15-2012 |
20120064180 | USE OF NO AND NO DONORS FOR TERMINATING DORMANCY IN INVERTEBRATES - The present invention relates to a method for terminating dormancy in an invertebrate, wherein said invertebrate is brought in contact with nitric oxide and/or a nitric oxide donor. The method can be used in pest management of unfavourable species, in eliminating dormant stages of aquatic invertebrates in ballast water in promoting termination of dormancy in beneficial species and/or in stimulating production of live food in aquacultures. | 03-15-2012 |
20120062978 | METHOD FOR OPERATING A MICROMIRROR DEVICE WITH ELECTROMECHANICAL PULSE WIDTH MODULATION - A method of operating by pulse width modulation a micromirror device is disclosed. In one aspect, the method includes providing a micromirror device having a micromirror element electrostatically deflectable around a rotation axis between a first and second position. The micromirror element is controllable by applying voltage signals to a first and second electrode on one side of the rotation axis and a third and fourth electrode on the other side. The method includes associating an intermediate value of intensity to the micromirror element during a time frame, the intensity being between a first value corresponding to the first position and a second value corresponding to the second position. The method includes switching the micromirror element between the first and second position. The intermediate value corresponds to the ratio of periods in the time frame in which the micromirror element is in the first or second position. | 03-15-2012 |
20120058551 | TECHNOLOGY AND METHOD TO STUDY MICROBIAL GROWTH AND ADHESION TO HOST-RELATED SURFACES AND THE HOST-MICROBIOTA INTERACTIONS - The present invention relates to in vitro adhesion modules that allow growth, stabilization and study of microbial communities that adhere to and colonize host-related surfaces, that mimic transport of chemical compounds across epithelial surfaces and simulate host-microorganism interactions and adaptation. It includes the provision of micromolar amounts of oxygen via the basal side of a mucus layer towards the adhered microorganisms thus establishing the microaerophilic conditions prevailing at the base of a biofilm. It can also include cells, simulating the host, in a chamber on the basal side of a functional layer comprising said mucus layer. The adhesion module of the present invention can be placed between the different compartments of the SHIME—the Simulator of the Human Intestinal Microbial Ecosystem. An extension of the SHIME is made where the duodenum, jejunum and ileum are separately mimicked. | 03-08-2012 |
20120029174 | METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step. | 02-02-2012 |
20120023624 | MEANS AND METHODS FOR MEDIATING PROTEIN INTERFERENCE - The present invention belongs to the field of functional proteomics and more particularly to the field of protein aggregation. The invention discloses a method for interfering with the function of a target protein and uses a non-naturally, user-designed molecule, designated as interferor, that has a specificity for a target protein and which induces aggregation upon contact with said target protein. The present invention also discloses such interferor molecules and their use in agrobiotech applications. | 01-26-2012 |
20120014749 | REMEDIATION OF POLLUTED MATERIALS OR SITES - The invention relates to a method and a system for controlling a remediation of a site polluted by contaminants, the method comprising the steps of determining a concentration gradient of gaseous emissions exhausting from the polluted site taking into account the measured indications measured at a plurality of spatially distinct positions, and controlling a remediation technique taking into account the concentration gradient. Automatic feedback for controlling the underlying remediation technique is thus enabled taking into account the concentration gradient. | 01-19-2012 |
20110311227 | Systems and Methods for Transferring Single-Ended Burst Signal Onto Differential Lines, Especially for Use in Burst-Mode Receiver - Systems and methods for transferring incoming single-ended burst signals of which at least one characteristic varies widely from burst to burst onto a pair of differential lines. The systems comprise an input for receiving an incoming burst signal, a signal adaptation block for adapting said widely varying characteristic and a single-ended-to-differential converter. In a first aspect a reset signal for resetting a settings determination block, which controls the signal adaptation block, is sent backwards over the differential lines, preferably using a common-mode signal. In a second aspect, a status freezing mechanism is employed for freezing the settings of the settings determination block after the end of the preamble of an incoming burst. | 12-22-2011 |
20110300562 | GDF15 AS A DIFFERENTIAL MARKER FOR SPONDYLOARTHROPATHY - In vitro methods for differential diagnosis of spondyloarthropathy are disclosed which involve determining the levels of GDF15 in biological samples. | 12-08-2011 |
20110300548 | GDF15 AS MOLECULAR TOOL TO MONITOR AND ENHANCE PHENOTYPIC STABILITY OF ARTICULAR CHONDROCYTES - The present invention relates to GDF15 as a molecular marker in in vitro assays determining phenotypic stability of articular chondrocytes and predicting the outcome of chondrocyte transplantation. | 12-08-2011 |
20110294864 | AQUEOUS COACERVATE COMPOSITIONS SUITABLE FOR MAKING POWDERS AND WATER-SOLUBLE FORMULATIONS OF BIOLOGICALLY-ACTIVE AGENTS - Aqueous gel-free two-phase coacervate compositions including a coacervate phase and an equilibrium water phase, comprising a mixture of:
| 12-01-2011 |
20110278441 | Transparent Photonic Integrated Circuit - Photonic structures and methods of operating the photonic structures are disclosed. In one embodiment, the photonic structure includes a detector configured to detect radiation of a first wavelength range. The radiation of the first wavelength range is received from an external radiation guide, and the detector is substantially transparent to radiation of a second wavelength range that differs from the first wavelength range. The photonic structure further includes a coupling structure configured to free space couple out of the photonic structure radiation of the second wavelength range. The photonic structure further includes a guiding structure configured to optically guide the radiation of the second wavelength range through the detector. | 11-17-2011 |
20110222856 | All-Optical 2R Regeneration - A method is provided for all-optical regeneration of intensity modulated optical signals. A DFB laser diode is selected such that it has a gain bandwidth comprising the signal wavelength, the signal wavelength being outside the stopband of the DFB laser diode. Furthermore, the DFB laser diode is selected such that it can have a bistable amplification characteristic for the signal wavelength showing a hysteresis with an ascending branch and a descending branch, the ascending branch located at a higher input power level than the descending branch. The DFB laser diode is driven such that it operates in the bistable amplification regime, the descending branch of the hysteresis curve located at an input power level above the lower power level of the optical signal pulses and the ascending branch of the hysteresis curve located at an input power level below the upper power level of the optical signal pulses. | 09-15-2011 |
20110191913 | CELLS PRODUCING GLYCOPROTEINS HAVING ALTERED GLYCOSYLATION PATTERNS AND METHOD AND USE THEREOF - The present application relates to the field of glyco-engineering, more specifically to eukaryotic cells wherein both an endoglucosaminidase and a glycoprotein are present. These cells can be used to deglycosylate or partly deglycosylate the (exogenous) glycoprotein, in particular without the need for adding an extra enzyme. Methods are also provided for the application of these cells in protein production. According to one specific aspect, the eukaryotic cells and methods are glyco-engineered yeast cells in which additionally at least one exogenous enzyme needed for complex glycosylation is present, e.g. allowing easier separation of differentially glycosylated glycoproteins. | 08-04-2011 |
20110190273 | METHODS AND COMPOSITIONS IN THE TREATMENT OF CORONAVIRUSES - The invention relates generally to the field of virology, and relates to the identification and characterization of the targets involved in the evasion strategy of viruses and to the use thereof in methods to identify anti-viral compounds. More in particular to identify compounds which are modulators of myosin light chain kinase (MLCK), a target within said entry and immune-evasion strategy. Other aspects of the invention are directed to anti-viral compounds identified using the models and methods of the present invention, as well as to the use thereof in treating viral infections, such as for example caused by the feline infectious peritonitis virus (FIPV), a coronavirus which belongs to an antigenic group which comprises in particular feline enteric coronavirus (FECV), canine coronavirus (CCV), swine transmissible gastroenteritis coronavirus (TGEV), porcine respiratory coronavirus (PRCV) and human coronavirus (HCV), and which induces, in a host-dependent manner, a range of symptoms which range from mild enteritis to the severe debilitating disease, and, in some cases, up to death. In a particular aspect the present invention provides the use of MLCK inhibitors for the treatment of feline infectious peritonitis (FIP). | 08-04-2011 |
20110184049 | LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF - The present invention relates to nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy. | 07-28-2011 |
20110162109 | Plants Having Modified Growth Characteristics and a Method for Making the Same - The present invention relates generally to the field of molecular biology and concerns a method for improving various economically important growth characteristics in plants. More specifically, the present invention concerns inter alia a method for modifying growth characteristics in plants by modulating expression in a plant of a nucleic acid encoding a HUB1 (Histone Monoubiquitination 1) polypeptide or encoding another protein useful in the methods of the present invention. The modified growth characteristics comprise a modification of light regulated phenotypes, such as modified circadian clock and/or circadian clock responses, or modified plant architecture. | 06-30-2011 |
20110150940 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 06-23-2011 |
20110136240 | DIAGNOSTIC TEST FOR THE DETECTION OF EARLY STAGE LIVER CANCER - The invention provides methods and kits to detect early stage hepatocellular carcinoma or a change in the gradation of hepatocellular carcinoma in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. | 06-09-2011 |
20110129525 | MUCOSAL MEMBRANE RECEPTOR AND USES THEREOF - The invention is based on the identification of aminopeptidase N (APN) as the receptor for F4 fimbriae of enterotoxigenic | 06-02-2011 |
20110116735 | Retro-Reflective Structures - A photonic integrated circuit ( | 05-19-2011 |
20110108646 | PROCESS AND APPARATUS FOR CONTINUOUS WET GRANULATION OF POWDER MATERIAL - An apparatus for wet granulating a powder material comprises:—a barrel having a granulation chamber and being provided with a first inlet ( | 05-12-2011 |
20110104183 | USE OF SIP1 AS DETERMINANT OF BREAST CANCER STEMNESS - The present invention relates to the diagnosis and treatment of cancer. More specifically, it relates to the use of SIP1 nucleic acid and/or protein for the detection of breast cancer stem cells, and the repression of the gene and/or the inactivation of the protein to repress the differentiation of cells into cancer cells and to inhibit metastasis of breast cancer tumors. | 05-05-2011 |
20110103743 | METHOD AND SYSTEM FOR COUPLING RADIATION - The present invention relates to a coupler ( | 05-05-2011 |
20110100816 | BLOOD SERUM MARKER FOR DETECTION AND DIAGNOSIS OF ALZHEIMER'S DISEASE - The present invention relates to a blood marker for early detection and diagnosis of Alzheimer's disease. More specifically, it relates to an analysis of the protein glycan profile in the blood, and the identification of specific peak ratio's when compared to healthy aged matched subjects that are typical for Alzheimer's dementia. | 05-05-2011 |
20110092374 | METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step. | 04-21-2011 |
20110082046 | METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE - The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step, wherein the identification purpose step is a detection step for the detection of an encoded microcarrier having an anisotropy in its shape. The invention further relates to an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscoper and means for the positioning and orientation of the microcarriers. | 04-07-2011 |
20110078825 | Modulation of plant cell number - The invention relates to the use of the ANG4 gene, or a variant thereof, to modulate the cell number of a plant organ. The modulation can be used to increase the plant biomass, or to adapt the plant architecture. | 03-31-2011 |
20110075970 | Integrated Photonics Device - The present invention relates to an integrated photonic device ( | 03-31-2011 |
20110075446 | Circuit for Converting a Pulsed Input Voltage to a DC Voltage - The present disclosure presents a circuit for converting a pulsed input voltage to a DC output voltage. The circuit comprises input nodes for receiving the pulsed input voltage and output nodes for outputting the DC output voltage. The circuit further comprises a first transistor and a second transistor connected between the input and the output nodes in a synchronous rectifier configuration. The first and second transistors each have a gate connected to a driving circuit configured for alternately charging the gates of the transistors whereby the driving circuit comprises an auxiliary circuit not directly connected to the input nodes and configured for providing a predetermined auxiliary supply voltage to the gates. In an embodiment, the auxiliary circuit comprises a buck DC-DC converter of which an input node is connected to the output nodes and of which an output node is connected to the gates. | 03-31-2011 |
20110069952 | Circuit for End-of-Burst Detection - A circuit for end-of-burst detection in a portion of a received bit stream is disclosed. The circuit comprises:
| 03-24-2011 |
20110065638 | NOVEL CRUSTACEAN ANDROGENIC GLAND HORMONE - The present invention relates to a novel crustacean androgenic gland hormone. More specifically, the invention relates to an androgenic gland hormone derived from | 03-17-2011 |
20110038887 | Novel Vaccine Against Trypanosoma Cruzi Infection - The present invention relates to a vaccine against | 02-17-2011 |
20110037179 | SEMICONDUCTOR PACKAGE - A semiconductor package is disclosed. In one aspect, the package includes a base frame and a wiring substrate mounted on the base frame. The base frame has two pieces made of a material with respectively a first and a second coefficient of thermal expansion and connected to each other via resilient connecting structures. The wiring substrate has electric wiring tracks providing the electric connection between first and second bond pads, provided for being electrically connected to bond pads on respectively a die and a printed wiring board. The electrical wiring tracks have flexible parts provided to expand and contract along with the resilient connecting structures. | 02-17-2011 |
20110027377 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from above about 20% to 50% by weight of the composition, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 85% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharma-ceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 02-03-2011 |
20110026921 | Systems and Methods for Transferring Single-Ended Burst Signal Onto Differential Lines, Especially for Use in Burst-Mode Receiver - Systems and methods for transferring incoming single-ended burst signals of which at least one characteristic varies widely from burst to burst onto a pair of differential lines. The systems comprise an input for receiving an incoming burst signal, a signal adaptation block for adapting said widely varying characteristic and a single-ended-to-differential converter. In a first aspect a reset signal for resetting a settings determination block, which controls the signal adaptation block, is sent backwards over the differential lines, preferably using a common-mode signal. In a second aspect, a status freezing mechanism is employed for freezing the settings of the settings determination block after the end of the preamble of an incoming burst. | 02-03-2011 |
20110021378 | NUCLEIC ACIDS OF PICHIA PASTORIS AND USE THEREOF FOR RECOMBINANT PRODUCTION OF PROTEINS - The present invention provides the genome sequence of | 01-27-2011 |
20110020406 | VIRAL INACTIVATION PROCESS - The invention relates generally to the field of virology. More particularly, the present invention relates to methods for determining the effect of a viral inactivation procedure on the antigenicity of the inactivated virus. In particular for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The invention further provides methods to determine the antigenicity of an inactivated virus as well as methods to screen for anti-viral compounds using any one of the aforementioned methods Methods of using the inactivated and immunogenic virus thus obtained, in particular in the manufacture of a vaccine are also provided by the present invention. | 01-27-2011 |
20110013874 | Method for Effective Refractive Index Trimming of Optical Waveguiding Structures and Optical Waveguiding Structures - A method for trimming an effective refractive index of optical waveguiding structures made for example in a high refractive index contrast material system. By compaction of cladding material in a compaction area next to patterns or ridges that are formed in the core material for realizing an optical waveguiding structure, the effective index of refraction of the optical waveguiding structure can be trimmed. Thus, the operating wavelength of an optical component comprising such an optical waveguiding structure can be trimmed. An optical waveguide structure thus obtained is also disclosed. | 01-20-2011 |
20110008454 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from 0.5% to 20% by weight of the composition, and excipients, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 80% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharmaceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 01-13-2011 |
20100330036 | MARKERS OF MATRIX GENE EXPRESSION AND CELLULAR DIFFERENTIATION IN CHONDROCYTES - The invention relates generally to the field of tissue engineering. More particularly, the present invention relates to methods for identifying a population of cells suitable for the repair of connective tissue, including cartilage. The invention further provides methods and compositions related to the generation of a population of cells suitable for the repair of cartilage, in particular in the repair of cartilage degeneration associated with osteoarthritis. Methods of using said cells thus identified or thus generated, in methods to extend the period of cell manipulation, i.e. to increase the yield of cells suitable in the aforementioned methods, are also provided by the present invention. | 12-30-2010 |
20100322555 | Grating Structures for Simultaneous Coupling to TE and TM Waveguide Modes - Disclosed are an integrated optical coupler, and a method of optically coupling light, between an optical element and at least one integrated optical waveguide. The optical coupler includes a grating structure and is adapted for coupling light to waveguide modes with different polarization with low polarization dependent loss. For example, polarization dependent loss may be smaller than 0.5 dB. The waveguide modes may include a Transverse Electric (TE) waveguide mode and a Transverse Magnetic (TM) waveguide mode. The optical coupler may further include a two-dimensional grating structure adapted for providing polarization splitting for a first optical signal of a first predetermined wavelength and for coupling both polarizations forward or backward. | 12-23-2010 |
20100321072 | Device and Method for Signal Detection in a TDMA Network - The present invention is related to a circuit ( | 12-23-2010 |
20100307241 | COMBINED MEMS ACCELEROMETER AND GYROSCOPE - A MEMS structure for a combined gyroscope and accelerometer unit ( | 12-09-2010 |
20100278484 | Waveguide Coupling Probe and Methods for Manufacturing Same - A waveguide coupling probe ( | 11-04-2010 |
20100234482 | FUNCTIONALISED POLYURETHANES - The present invention relates to a method for producing an isocyanate-based polymeric material by polymerizing a reaction mixture which comprises different reaction components, including at least one polyisocyanate component and at least one component which is reactive towards said polyisocyanate component. The reaction components comprise at least one anchor component which has at least one anchor group which enables to bond a functional component covalently to the polymeric material. The anchor group is a reactive unsaturated group which does not react during the polymerisation process so that the polymerisation process is not interfered. The anchor group is selected to that it can bind the functional component by a click chemistry reaction to the polymeric material. It is more particularly selected so that it can participate in a catalysed Huisgen 1,3-dipolar cycloaddition reaction or in a Diels-Alder cycloaddition reaction The invention also relates to the obtained isocyanate-based polymeric material, to the use thereof to produce a functionalised polymeric material and to this functionalised polymeric material. | 09-16-2010 |
20100183750 | FORTIFICATION OF PLANTS WITH FOLATES BY METABOLIC ENGINEERING - The invention relates to a transgenic plant overexpressing a polynucleotide encoding a plant GTP cyclohydrolase I (GTPCHI) enzyme. The present invention also relates to a product comprising the transgenic plant of the invention or a harvestable part, plant organ, plant tissue, plant cell, seed, or a propagule of said plant. The present invention further elucidate the use of the plant of the invention to cross breed with other plants, as biofortification to enrich the quality of the food intake of an animal or human subject, for the manufacture of a medicament to prevent folate insufficiency, or, for the treatment of folate insufficiency or diseases or disorders resulting from said insufficiency in an animal or human subject. | 07-22-2010 |
20100160455 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS - Novel vitamin D analogues are useful for making pharmaceutical compositions for the prevention or treatment of bone disorders such as osteoporosis | 06-24-2010 |
20100152253 | NON-STEROIDAL BRASSINOSTEROID MIMETIC - The present invention relates to non-steroidal mimetics of brassinosteroids. More specifically, it relates to non-steroidal monocyclic compounds, capable of rescuing the brassinosteroid receptor null mutation bri1-116. Preferably, said compounds are low molecular weight, monocyclic halogenated compound. | 06-17-2010 |
20100119229 | METHOD AND SYSTEM FOR MULTIPLEXER WAVEGUIDE COUPLING - An optical device for optically multiplexing or demultiplexing light of different predetermined wavelengths is provided, the optical device comprising at least one first waveguide ( | 05-13-2010 |
20100093807 | SUBSTITUTED 7-AZABICYCLO[2.2.1]HEPTYL DERIVATIVES USEFUL FOR MAKING PHARMACEUTICAL COMPOSITIONS - This invention provides 1-substituted-7-azabicyclo[2.2.1]heptyl derivatives, intermediates and methods for producing them, which are therapeutic agents useful for the prevention and treatment of central nervous system disorders and diseases mediated by a Nicotinic Acetylcholine Receptor such as Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, pain, nicotine addiction and dementia. | 04-15-2010 |
20090326078 | PROCESS FOR PREPARING A SOLID DOSAGE FORM - This invention provides a process for preparing a solid dosage form, comprising:—preparing an aqueous slurry, solution or suspension of (a) a powder material, and (b) a mixture of one or more polyols and one or more maltodextrins, and—spray drying the resultant aqueous slurry, solution or suspension, thereby obtaining particles which are directly compressible into a solid dosage form being able to disintegrate in an aqueous medium within no more than 15 minutes. | 12-31-2009 |
20090317639 | METHOD FOR MANUFACTURING A STRETCHABLE ELECTRONIC DEVICE - A method for manufacturing a stretchable electronic device is disclosed. In one aspect, the device comprises at least one electrically conductive channel connecting at least two components of the device. The method comprises forming the channel by laser-cutting a flexible substrate into a predetermined geometric shape. | 12-24-2009 |
20090298066 | Sex-Specific Marker for Shrimps and Prawns - The present invention relates to a sex-specific marker for shrimps and prawns. More specifically, it relates to a sex-specific PCR-based molecular marker, derived from | 12-03-2009 |
20090285856 | HELICOBACTER SPECIES AND CULTIVATION THEREOF - The present invention relates to the isolation and cultivation of “Candidatus | 11-19-2009 |
20090275616 | STRAIGHTFORWARD ENTRY TO 7-AZABICYCLO[2.2.1]HEPTANE-1-CARBONITRILES AND SUBSEQUENT SYNTHESIS OF EPIBATIDINE ANALOGUES - The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction. | 11-05-2009 |
20090263863 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST - The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided. | 10-22-2009 |
20090239900 | QUININE AND QUINIDINE SALTS, METHODS FOR MAKING THEM, AND PHARMACEUTICAL FORMULATIONS COMPRISING THEM - The present invention provides a combination of:
| 09-24-2009 |
20090222952 | Plants Having Improved Growth Characteristics And A Method For Making The Same - The present invention concerns a method for increasing plant yield and/or increased stress resistance by decreasing the level of activity of a DEL1 polypeptide. One such method comprises introducing into a plant a nucleic acid comprising a variant DEL1 nucleic acid. Another method comprises downregulating expression of a DEL1 gene. The invention also relates to transgenic plants having introduced therein a variant DEL1 nucleic acid thereof, which plants have increased yield and/or increased stress resistance relative to control plants. The present invention also concerns a novel DEL1 protein and its encoding sequence, and constructs useful in the methods of the invention. | 09-03-2009 |
20090151021 | Novel Stress-Related MicroRNA Molecules and Uses Thereof - Naturally occurring and synthetic novel stress-related miRNAs are provided which can be used to modify the stress tolerance of plants. | 06-11-2009 |
20090107704 | COMPOSITE SUBSTRATE - A composite substrate is disclosed. In one aspect, the substrate has a stretchable and/or flexible material. The substrate may further have patterned features embedded in the stretchable and/or flexible material. The patterned features have one or more patterned conducting layers. | 04-30-2009 |
20090100545 | Means and Methods to Modulate Flavonoid Biosynthesis in Plants and Plant Cells - The present invention provides a method for increasing the flavonoid content of plants and plant cells wherein said method comprises increasing the activity of genes implicated in the flavonoid biosynthesis pathway. The invention further relates to recombinant plant and plant cells obtainable by the process of the invention and to flavonoids made there from. | 04-16-2009 |
20090087882 | Protein secretion in eukaryotic cells - The invention relates to the use of a glucosidase II mutation to increase protein secretion in yeast cells. The invention relates further to the use of yeast cells, comprising a mutant glucosidase II gene, possibly in combination with the expression of a recombinant α-1,2-mannosidase gene and/or a recombinant N-acetylglucosaminyl-transferase gene, as a host for protein secretion. | 04-02-2009 |
20090041852 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 02-12-2009 |
20090029999 | Synephrine derivatives useful as anti-inflammatory agents - This invention provides compounds having the structural formula: | 01-29-2009 |
20090028892 | Ostertagia Vaccine - The present invention relates to nucleic acid sequences encoding | 01-29-2009 |
20080312190 | Organophosphoric Derivatives Useful as Anti-Parasitic Agents - The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, C | 12-18-2008 |
20080310456 | Communication System over a Power Line Distribution Network - The present disclosure provides a system for receiving signals over a power line distribution. Typically, problems of noise and interference are being solved at the receiver side. Systems of the present disclosure, however, are not limited to the receiver-side solution. Systems according to the present disclosure may also be used at the transmitter side. The receiver comprises a high pass filter, a preselect crossover filter, and an analog front-end receiver architecture. | 12-18-2008 |
20080271208 | Modulation of Plant Cell Number - The present invention relates to the use of the ANG4 gene, or a variant thereof, to modulate the cell number of a plant organ. Said modulation can be used to increase the plant biomass, or to adapt the plant architecture. | 10-30-2008 |
20080262160 | Monodisperse Polymers Containing (Alkyl)Acrylic Acid Moieties, Precursors and Methods for Making them and their Applications - This invention relates to monodisperse or nearly monodisperse (co)polymers containing acrylic or (α-substituted)acrylic acid moieties, polymeric precursors thereof as well as methods for making them by at least partial hydrolysis of said polymeric precursors. The invention also relates to compositions comprising such (co)polymers optionally in combination with polymer processing additives for use in various fields of technology including imaging applications. | 10-23-2008 |
20080254069 | VACCINES FOR IMMUNIZATION AGAINST HELICOBACTER - The invention relates to the immunisation of pigs against | 10-16-2008 |
20080220473 | Endo-N-Acetyl-Beta-D-Glucosaminidase Enzymes of Filamentous Fungi - The present invention discloses mannosyl-glycoprotein endo-beta-N-acetylglucosamidase (E.C.3.2.1.96, endo-N-acetyl-beta-D-glucosaminidase acting on the di-N-acetylchitobiosyl part of N-linked glycans) from filamentous fungi such as | 09-11-2008 |