4SC AG Patent applications |
Patent application number | Title | Published |
20150335636 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES - Imidazoquinolines of formula I that contain substituted amine or amide functionality at 1-position and that are effective as Toll like Receptor 7 activators are disclosed. These compounds are useful as anticancer agents. | 11-26-2015 |
20120035175 | Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents - The present invention relates to a salt selected from the group comprising the N-methyl-D-glucamine salt (NMG), the diethylamine salt (DEA) salt, the magnesium salt, the tromethamine salt, the choline salt, the L-arginine salt, the zinc salt, and the 4-(2-hydroxyethyl)morpholine (HEM) salt of compounds of the general formula (I) | 02-09-2012 |
20120029034 | Novel calcium salts of Compound as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents - The present invention relates to calcium salts of compounds of the general formula (I) | 02-02-2012 |
20120028985 | COMBINATIONAL THERAPY FOR TREATING AUTOIMMUNE DISEASE - The present invention relates to the treatment and prevention of immunological and inflammatory disorders with a compound of formula (I) in combination with methotrexate, | 02-02-2012 |
20120022068 | NOVEL HETEROCYCLIC NF-kB INHIBITORS - The present invention relates in one embodiment to compounds of formula (Ih) and/or a pharmaceutically acceptable salt thereof with an acid or a base, and/or a pharmaceutically acceptable prodrug and/or a stereoisomer thereof, | 01-26-2012 |
20110263486 | Inhibitors of Cancer Cell, T-Cell and Keratinocyte Proliferation - The invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, | 10-27-2011 |
20110245289 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES - Imidazoquinolines of formula I that contain substituted amine or amide functionality at 1-position and that are effective as Toll like Receptor 7 activators are disclosed. These compounds are useful as anticancer agents. | 10-06-2011 |
20110201643 | NOVEL N-SUBSTITUTED TETRAHYDROISOQUINOLINE/ISOINDOLINE HYDROXAMIC ACID COMPOUNDS - Compounds of a certain formula (I) wherein R1, R2, R3, X, Y, r, s, t, u and v have the meanings as defined in the specification, and the salts, solvates and hydrates thereof are novel effective HDAC 6 inhibitors. | 08-18-2011 |
20110172241 | Benzazole analogues and uses thereof - The present invention relates to compounds of the general formulas (I), (Ia) and (II) and salts and physiologically functional derivatives thereof, | 07-14-2011 |
20110105568 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS - Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II′): wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof. | 05-05-2011 |
20110091889 | CENTROSOME-ASSAY - The present invention provides a centrosome assay for the identification of preferably, Eg | 04-21-2011 |
20110086897 | (E)-N-(2-Amino-phenyl)-3--acrylamide salts - A salt of (E)-N-{2-amino-phenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)-beπzenesulfonyl]-1H-pyrrol-3-yl)-acrylamide selected from the group consisting of the hydrobromide, methansulfonate, hemi ethane-1,2-disulfonate, benzenesulfonate, toiuenesulfonate and 2-naphthalenesulfonate. | 04-14-2011 |
20110077404 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE INDOLOPYRIDINES - The invention relates to a novel process for the preparation of pharmacologically interesting indolopyridine derivatives containing tetracyclic tetrahydro-β-carboline-hydantoines linked to a basic side chain and the corresponding salts, which can be used as Eg5 inhibitor, with very high overall chemical yield and enantiomeric purity. | 03-31-2011 |
20110065734 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES - The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth. | 03-17-2011 |
20110027226 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5) - Compounds of a certain formula I, in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity. | 02-03-2011 |
20110021494 | NOVEL TETRAHYDRO-FUSED PYRIDINES AS HISTONE DEACETYLASE INHIBITORS - The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases. | 01-27-2011 |
20100280081 | ANTI-INFLAMMATORY AGENTS AS VIROSTATIC COMPOUNDS - The present invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, | 11-04-2010 |
20100267717 | Novel Heterocyclic NF-kB Inhibitors - The present invention relates in one embodiment to compounds of formula (Ih) and/or a pharmaceutically acceptable salt thereof with an acid or a base, and/or a pharmaceutically acceptable prodrug and/or a stereoisomer thereof, | 10-21-2010 |
20100197640 | NOVEL SULFAMOYL-PHENYL-UREIDO COMPOUNDS AND THEIR USE AS MEDICAMENT - The present invention relates to novel sulfamoyl-phenyl-ureido compounds having the formula (I) or a physiologically acceptable salt or derivative thereof which are suitable for the therapy of infections caused by protozoa and in particular uncomplicated or severe malaria caused by plasmodia. | 08-05-2010 |
20100048583 | Novel Heterocyclic NF-kB Inhibitors - The present invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, | 02-25-2010 |
20100048574 | NOVEL HETEROCYCLIC NF-kB INHIBITORS - The present invention relates to compounds of the general formula (II): | 02-25-2010 |
20100004258 | Novel Heterocyclic NF-kB Inhibitors - The present invention relates to compounds of the general formula (III): | 01-07-2010 |
20090270410 | BENZAZOLE ANALOGUES AND USES THEREOF - The present invention relates to compounds of the general formulas (I), (Ia) and (II) and salts and physiologically functional derivatives thereof, | 10-29-2009 |